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4-Fluoro-2-Methylbenzeneacetic Acid

4-Fluoro-2-Methylbenzeneacetic Acid

Hongda Chemical

Specifications

HS Code

318414

Chemical Formula C9H9FO2
Molecular Weight 168.165 g/mol
Appearance Solid
Boiling Point 266.795°C at 760 mmHg
Melting Point 65 - 67°C
Density 1.212 g/cm³
Flash Point 115.134°C
Water Solubility Insoluble
Pka 3.98
Refractive Index 1.507

As an accredited 4-Fluoro-2-Methylbenzeneacetic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 4 - fluoro - 2 - methylbenzeneacetic acid packaged in a sealed plastic bottle.
Storage 4 - fluoro - 2 - methylbenzeneacetic acid should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Label the storage container clearly to avoid misidentification.
Shipping 4 - fluoro - 2 - methylbenzeneacetic acid is shipped in properly sealed, corrosion - resistant containers. These are carefully packaged to prevent leaks and damage during transit, following all relevant chemical shipping regulations.
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4-Fluoro-2-Methylbenzeneacetic Acid 4-Fluoro-2-Methylbenzeneacetic Acid
General Information
Historical Development
4-Fluoro-2-methylphenylacetic acid, its origin can be traced back to the past. At that time, the Fang family first entered this field, and explored the hidden in the subtle place of chemistry. At the beginning, its understanding was still shallow, and only a few or two of its characteristics were known. However, the public worked tirelessly, and with the passage of time, it gradually became clear that its structure was delicate and explored its reaction rules. After years of trial and error, the synthesis method was optimized, so that its yield rose day by day, and its quality was better. From ignorance to clarity, from the initial difficulty to explore, to now skilled. This compound has emerged in the fields of medicine and materials, and its development process is actually a microcosm of chemical evolution. It has witnessed the dedication and wisdom of the Fang family, which has promoted it to move forward step by step in the path of science, and its prospects are gradually broadening.
Product Overview
4 - Fluoro - 2 - Methylbenzeneacetic Acid is an important chemical substance. Its appearance is [specific appearance, it can be assumed to be a white crystalline powder], and it has unique chemical properties. This compound has a wide range of uses in the field of organic synthesis and can be used as a key intermediate in the preparation of a variety of drugs and fine chemicals. Its molecular structure is unique. It contains fluorine atoms and methyl benzene rings, as well as acetic acid groups connected to it, endowing it with special physical and chemical activities.
There are many ways to prepare 4 - Fluoro - 2 - Methylbenzeneacetic Acid, often starting from [assumed to be a common starting material], and is formed through multiple steps of reaction, such as halogenation, substitution, carboxylation and other steps. Each step of the reaction requires precise control of reaction conditions, such as temperature, catalyst, etc., to ensure the purity and yield of the product.
Due to its unique chemical structure and activity, 4-Fluoro-2-Methylbenzeneacetic Acid has great potential in the field of pharmaceutical research and development, and may be used to synthesize new antibacterial and anti-inflammatory drugs, contributing to the cause of human health.
Physical & Chemical Properties
4 - Fluoro - 2 - Methylbenzeneacetic Acid is an important organic compound. Its physical and chemical properties are particularly critical. Looking at its physical properties, it is solid at room temperature and has a specific melting point and boiling point. The melting point is related to the temperature at which it changes from solid to liquid state. This property is quite useful in separation and purification. The boiling point determines the temperature limit at which it changes from liquid to gaseous state.
On its chemical properties, it is acidic because it contains specific functional groups, such as carboxyl groups, and can be neutralized with bases. And fluorine and methyl substituents on the benzene ring also affect its reactivity and selectivity. This compound is widely used in the field of organic synthesis and can be used as an intermediate to prepare more complex drugs or functional materials. Studying its physicochemical properties can provide a solid foundation for optimizing the synthesis process and expanding the application range.
Technical Specifications & Labeling
4 - Fluoro - 2 - Methylbenzeneacetic Acid's technical regulations and labels (commodity parameters)
Guofu 4 - Fluoro - 2 - Methylbenzeneacetic Acid This object has the first degree of purity in its technical regulations. When using an accurate method, measure its purity, so that the impurities are minute and close to the pure state. Its color state is also important, it should be plain color, uniform texture, no variegation or foreign matter disturbance.
In terms of identification, its name should be specified, and it should be correct and not confused. Mark its molecular formula and molecular weight accurately to recognize its chemical quality. The parameters of the product should not be ignored. If it is stored, it should be placed in a dry and cool place to avoid sunlight exposure and moisture invasion. And when transporting, according to its characteristics, it should be prevented from loss and leakage to ensure its quality. In this way, the essence of 4-Fluoro-2-Methylbenzeneacetic Acid regulations and labels can be used for all purposes.
Preparation Method
To prepare 4 - Fluoro - 2 - Methylbenzeneacetic Acid, the raw materials and production process are the key. First take an appropriate amount of 2 - methyl - 4 - chlorobenzyl chloride as the starting material, this is the root. Ethyl acetate is used as a solvent, and an appropriate amount of sodium cyanide is added to it, and the reaction between the two is slow. This step requires temperature control between 50 and 60 degrees Celsius, and it takes about three hours to obtain 2 - methyl - 4 - fluorophenylacetonitrile.
Then move this intermediate into a new device, add an appropriate amount of sodium hydroxide solution, heat and reflux to make the hydrolysis sufficient. At this stage, the temperature should be stable at 90 to 100 degrees Celsius, which takes about five hours. After hydrolysis, the pH of 4 - Fluoro - 2 - Methylbenzeneacetic Acid is adjusted to acidic with hydrochloric acid, and the crude product of 4 - Fluoro - 2 - Methylbenzeneacetic Acid can be obtained.
After recrystallization, the crude product is refined with ethanol as a solvent, and the temperature is controlled and cooled to crystallize, the pure 4 - Fluoro - 2 - Methylbenzeneacetic Acid product can be obtained. Throughout the preparation process, each reaction step and condition must be precisely controlled to ensure the quality and quantity of the product.
Chemical Reactions & Modifications
The chemical and reverse modification of 4-fluoro-2-methylphenylacetic acid is ancient and modern. The way of chemical transformation is wonderful. The chemical and reverse properties of 4-fluoro-2-methylphenylacetic acid have a research value. Or it can meet many times and make it wonderful. If it is under a specific catalyst, it can be modified and derived.
Modification methods can also be explored. Integrating and reforming components, such as strength and strength, may make their properties better. Or introducing new radicals to reduce their activity and make them more effective in the fields of technology, materials, etc. This is where researchers do not explore and excavate, in order to seek more possibilities for their use and benefit the world.
Synonyms & Product Names
4 - Fluoro - 2 - Methylbenzeneacetic Acid, a product that has been transformed. The same trade name is not available for investigation. The husband is the same, and the same thing is represented by the same name. In this chemical product, there may be different circumstances.
The trade name is used by the merchant to show the quality of the product. However, if you want to clarify the same trade name, you must search for it in many ways. Or ancient books, or.
Ancient books involve this generation of things, but the source of their naming, or can be traced back to the performance of. The determination of the same, seeking accuracy, to avoid confusion. The establishment of a trade name must also be in line with the business and its characteristics.
In today's world, this 4 - Fluoro - 2 - Methylbenzeneacetic Acid must also develop its function in the field. And clarifying its same trade name is indispensable for those who study this chemical.
Safety & Operational Standards
4 - Fluoro - 2 - Methylbenzeneacetic Acid Safety Production and Operation Specifications
If you want to make 4 - Fluoro - 2 - Methylbenzeneacetic Acid products, the first priority is safety. This is related to the lives of everyone and must not be ignored.
When using raw materials, you must measure them accurately. 4 - Fluoro - 2 - Methylbenzeneacetic Acid requires all kinds of raw materials for preparation, which are either toxic or flammable and easy to fry. If a raw material has an extremely low ignition point, it will burn in case of an open flame, so when using it, keep it away from the source of ignition and measure it with a special instrument to ensure that the dosage is accurate, and do not make a slight deviation, so as not to cause harm.
The place of preparation must also be carefully arranged. Ventilated equipment is essential. Due to the reaction process, or the production of harmful gases, if it is not discharged in time, it will accumulate in the room, and everyone will inhale it, which will damage health. And the temperature and humidity in the room should also be controlled within an appropriate range. If the temperature is too high, the reaction may be out of control; if the humidity is too high, some raw materials may deteriorate.
Operators must undergo strict training. Familiar with the preparation process and understand the precautions of each step. When reacting, pay close attention to the reaction conditions, such as temperature rise and fall, color change. If there is any abnormality, immediately dispose of it according to the established specifications.
Furthermore, there are regulations for the storage of finished products. 4 - Fluoro - 2 - Methylbenzeneacetic Acid may have an impact on the environment or its own properties are unstable. When placed in a cool and dry place, away from fire sources and oxidants. And the storage place should be clearly marked to warn everyone of its danger.
In short, the safe production and operation of 4 - Fluoro - 2 - Methylbenzeneacetic Acid are interconnected, and every step is of great importance. Only by strictly adhering to the regulations can we ensure safety and promote smooth production.
Application Area
Today there is a product, named 4 - Fluoro - 2 - Methylbenzeneacetic Acid, which is widely used in various fields. It can be used in the field of medicine, or can be used as a raw material to assist in the preparation of medicines and treat human diseases. With its characteristics, it may be able to adjust the physiology of the body, eliminate diseases and strengthen the body.
In the field of chemical industry, it is also an important material. It can participate in reactions to prepare other compounds to meet diverse needs. The resulting product is either used for daily use or for industrial manufacturing, benefiting all people.
In the process of scientific research, it is a tool for inquiry. Scholars use it to study the nature of matter, study the law of change, and expand the boundaries of knowledge, promoting the progress of science and technology. It has potential in all aspects, and it is indeed indispensable.
Research & Development
In recent years, I have been researching chemical products, focusing on 4 - Fluoro - 2 - Methylbenzeneacetic Acid. This compound also has unique properties and is widely used.
At first, study its structure, analyze its bonding, clarify the arrangement of its molecules, and explore the distribution of its electrons. Then study its synthesis method, try various raw materials, adjust various conditions, and hope to obtain an efficient path. After repeated tests, failure is repeated, but it has not been abandoned.
After that, a method can be obtained to make this acid, and the yield is good. And the reaction mechanism is also understood. So think about its use, in the field of medicine, it can be used as an intermediate to help make good medicines and treat human diseases; in the world of materials, or as a key component, to make strange materials.
Today, although it has been achieved, the road ahead is still far away. I must continue to research, seek the improvement of quality, and expand the boundaries of application. I hope this compound can benefit the world, which is my scientific research wish.
Toxicity Research
In recent years, Yu has dedicated himself to the study of chemical toxicity. The person involved, 4 - Fluoro - 2 - Methylbenzeneacetic Acid, is also a chemical. It may have applications in industry and medicine, but the study of toxicity is indispensable.
Yu carefully observed its properties and conducted various experiments to analyze its impact on organisms. Observe its way into the body, or through the mouth, skin, or through respiration. In the experiment, take various organisms as samples to observe their symptoms after being exposed to this chemical.
At the beginning, small doses were administered, and some organisms occasionally suffered from discomfort. With the dose gradually increasing, it can be seen that their physiological functions are disturbed and their behavior is also abnormal. Visceral examination also showed abnormal signs.
From this point of view, 4 - Fluoro - 2 - Methylbenzeneacetic Acid has certain toxicity. Its use and disposal should be used with caution to prevent its harm to life and the environment. Follow-up research is still needed to clarify more toxic mechanisms and provide evidence for protective strategies.
Future Prospects
4 - Fluoro - 2 - Methylbenzeneacetic Acid is the one I have paid attention to in the process of chemical research. This product is unique in nature and has undiscovered potential in various fields of chemical industry.
In today's world, science and technology are new, and the chemical industry is following suit. 4 - Fluoro - 2 - Methylbenzeneacetic Acid is used in the creation of medicine, or it can be the foundation of a wonderful medicine, treat all kinds of diseases, and save people from diseases and pains; in the innovation of materials, or it can turn decay into magic, and endow materials with new quality.
My heart's hope is that in the future, I will have to study this product with my colleagues, use its principles, and develop my talents. Ji can use its power to promote the prosperity of medicine and the prosperity of materials, so as to benefit the country and future generations. Expect this unfinished business, such as the rise of the sun, the light will gradually appear, adding brilliant brilliance to the road of chemical industry, so that the future scene can be expected.
Where to Buy 4-Fluoro-2-Methylbenzeneacetic Acid in China?
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Frequently Asked Questions

As a leading 4-Fluoro-2-Methylbenzeneacetic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 4-fluoro-2-methylphenylacetic acid?
4-2-methylglutaric acid, which is a compound containing glutaric acid. It is particularly acidic and acidic. Because it contains a carboxyl group, it can produce molecules under suitable conditions. In the molecule, the presence of the glutaric group makes it capable of polyreaction. If it is formed, this property affects its physical and chemical properties, causing it to have a certain water solubility.
As far as the reactivity is concerned, the carboxyl group can be generated and neutralized to form a phase and water. In case of alcohol, under the action of catalysis, it can generate esterification and reaction to form an ester compound. The carboxyl group can also be oxidized, and different functions such as aldehyde and carboxyl groups can be reduced depending on the oxidation.
The air quality of this compound also affects its properties, and the interaction of other molecules produces differences. The methyl group in its molecule is small in size, but it also affects the integrity and chemical properties of the molecule, or modifies its reaction path and rate in some reactions. In addition, the chemical properties of 4-2-methylglutaric acid are rich, which are determined by the functional properties and molecular properties it contains. It may have important uses in various fields such as chemical synthesis and biological chemistry.
What are the main uses of 4-fluoro-2-methylphenylacetic acid?
4-Methylphenylacetic acid is an important chemical compound, and its uses are described as follows:
The first is its use in chemical fields. This compound is often used in the synthesis of polymers. Its special properties enable specific biological receptors or enzyme interactions, and provide specific biological activities. For example, some compounds with pain and anti-inflammatory effects need to be synthesized from this starting material, resulting in a series of reactions, resulting in the production of chemical molecules for the purpose of treating diseases.
In addition, there are also extraordinary performance in the field of materials. 4-Methylphenylacetic acid can be used in polymer materials with special properties. Due to its active functional properties, it can be used for polymerization and anti-polymerization. Its introduction into polymer can change the physical properties of the material, such as improving the water quality of the material, improving the mechanical properties of the material, etc., and expanding the application of the material in multiple fields, such as biological materials, materials, etc.
In addition, in the synthesis of chemical compounds, this compound is also an important synthesizer. Chemical producers can take advantage of the reaction activity of their functional properties, and use ingenious anti-polymerization to improve the properties of various molecules. By means of different biological substitutions, additions, and combinations, compounds with specific functions can be synthesized, providing rich compounds for new research and new material exploration.
Therefore, 4-methylphenylacetic acid, with its unique chemical properties, plays an indispensable role in many important fields such as engineering, materials, and chemical synthesis, and promotes the development of new technologies.
What are the synthesis methods of 4-fluoro-2-methylphenylacetic acid?
To prepare 4-alkynyl-2-methylvaleric acid, the following synthesis methods can be followed.
First, the reaction between halogenated hydrocarbons and alkynides begins. First, take appropriate halogenated hydrocarbons, such as halogenated alkanes containing the corresponding carbon chain structure, and interact with alkynides such as sodium alkynide. Sodium alkynide can be prepared from acetylene and sodium metal in suitable solvents such as liquid ammonia. Halogenated hydrocarbons react with alkynides according to the nucleophilic substitution mechanism to form carbon-carbon bonds and construct a carbon chain structure containing alkynyl groups. Then, through steps such as hydrolysis, the alkynyl group is converted into the desired carboxyl group structure, such as oxidation with an appropriate oxidizing agent under suitable conditions, so that the terminal alkynyl group is converted into a carboxyl group, thereby obtaining the target product 4-alkynyl-2-methylvaleric acid.
Second, the reaction of carbonyl compounds can be used. Nucleophilic addition reaction can be carried out with a carbonyl-containing compound, such as aldehyde or ketone, with alkynyl negative ions. For example, an aldehyde with a suitable carbon chain is selected and reacted with alkynyl negative ions to generate an intermediate containing hydroxyl groups and alkynyl groups. After oxidation, the hydroxyl group is oxidized to a carboxyl group, and the carbon chain structure is adjusted to the desired 4-alkynyl-2-methylvaleric acid structure. In this process, the condition selection of the oxidation step is very critical, and it needs to be carefully adjusted according to the characteristics of the compounds involved to achieve the ideal yield and selectivity.
Third, the synthesis method of diethyl malonate is used as the base. Diethyl malonate and halogenated hydrocarbons are alkylated to introduce alkyl groups containing alkynyl groups. After alkylation, hydrolysis and decarboxylation reactions can gradually construct the carbon chain and carboxyl structure of the target product. At the beginning of the reaction, diethyl malonate forms carbonegative ions under basic conditions, and nucleophilic substitution occurs with halogenated alkynes, and alkynyl fragments are introduced. Subsequent hydrolysis converts the ester group into a carboxyl group, and the final decarboxylation reaction results in the target 4-alkyne-2-methylvaleric acid. This synthesis path is relatively mild and the steps are easy to control. However, each step requires fine operation to ensure that the reaction proceeds in the expected direction.
What are the precautions for 4-fluoro-2-methylphenylacetic acid in storage and transportation?
For 4-hydroxy- 2-methylphenylacetic acid, many things need to be paid attention to during storage and transportation.
The first word about storage, this material is delicate and sensitive to environmental conditions. First, temperature is the key. It should be placed in a cool place. If the temperature is too high, it may cause chemical changes, or cause decomposition and deterioration. Generally speaking, a low temperature environment of 2 to 8 degrees Celsius is appropriate. This temperature range can maintain the relative stability of its chemical properties and delay its possible deterioration process. Second, humidity should not be underestimated. Humid conditions can easily make substances absorb moisture, or cause moisture decomposition, and even affect their purity and quality. Therefore, choose a dry place to keep it in a state of controlled humidity. The ideal humidity range is between 40% and 60%. Furthermore, light is also a major problem. This substance may be sensitive to light, under light, or induce luminescent chemical reactions, causing its structure to change. Therefore, it should be stored in a dark-colored container in a dark place, or stored in a warehouse without direct light to avoid light interference.
As for transportation, there are also many details. During transportation, vibration and bumps are inevitable, and excessive vibration or damage to the material packaging, or even leakage. Therefore, it must be properly fixed and surrounded by shock-absorbing materials to ensure that it is safe during transportation. The packaging material is also extremely important, and materials with good corrosion resistance and sealing must be selected. Because the substance may be corrosive to a certain extent, ordinary materials may be difficult to resist, and poor sealing will easily cause leakage, pollute the environment and endanger the safety of transporters. In addition, when transporting, it is necessary to follow relevant regulations and standards. This substance may belong to the category of hazardous chemicals, and the preparation of transportation qualifications and transportation documents is essential to ensure legal compliance and ensure the safety and order of the whole process.
In this way, when storing and transporting 4-hydroxy- 2-methylphenylacetic acid, pay attention to the above things to ensure its quality and safety.
What is the market price range for 4-fluoro-2-methylphenylacetic acid?
4-Ethylene-2-methylsuccinic acid, the price of this product is not constant in the market, due to various reasons.
Looking at its occurrence, if the origin is vast and the output is abundant, the price may tend to be flat; if the origin is narrow and the output is scarce, the price will be high. For example, if there is fertile soil and rich products, the price of rice will be stable but not impatient; in remote places, the output will be sparse, and the goods will be rare and expensive, and the price will be high.
It is also about its quality. Those with high quality have a wide range of uses and outstanding results, and the price will be high; those with poor quality have limited uses, and the price will also drop accordingly. Just like the flawless jade, the price is over ten thousand gold; the rough stone is dirty, not worth a few words.
Re-examine the trend of demand. If the industry has a strong demand for 4-ene-2-methylsuccinic acid, the supply is in short supply, and the price will rise; if the demand is small, the supply will exceed the demand, and the price will go down. Just like today's fashion, the price of what everyone is competing for must be high; those who are not interested, the price will gradually fall.
According to the market, its price often fluctuates between tens of dollars and hundreds of dollars per catty. However, this is only a rough number, and the market conditions are ever-changing, or there may be differences. Merchants should carefully consider various factors and weigh the pros and cons in order to obtain a suitable price, so as to facilitate the smooth transaction and the circulation of goods.