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What is the chemical structure of 4-Fluoro-alpha - (2-Methyl-1-Oxopropyl) -Y-Oxo-N, β-Diphenylbenzene Butaneamide?
This substance "4 - Fluoro - α - ( 2 - Methyl - 1 - Oxo propyl ) - γ - Oxo - N, β - Diphenylbenzene Butaneamide", according to organic chemistry naming rules, its structure is roughly as follows:
This substance belongs to phenylbutylamide derivatives. The core structure is phenylbutylamide, "4 - Fluoro" indicates that the 4 position of the benzene ring is connected with a fluorine atom ;“α - ( 2 - Methyl - 1 - Oxopropyl) "means that the carbon atom at the α position connected to the amide group is connected to a 2 - methyl - 1 - oxopropyl group, and the 1 position of the propyl group is a carbonyl group;" γ - Oxo "refers to the presence of a carbonyl group at the γ position of the butylamide;" N, β - Diphenyl "indicates that the nitrogen atom and the carbon atom at the β position are each connected to a phenyl group.
Specific structure description: First draw the basic skeleton of phenylbutylamide, that is, the benzene ring is connected to the tetracarbon chain, and the end is the amide group (-CONH -). A fluorine atom is added at the 4th position of the benzene ring; the carbon atom at the α position is connected to 2-methyl-1-oxopropyl, and the carbonyl at the 1st position of the propyl is connected to the carbon at the α position; a carbonyl is added to the carbon at the γ position; the nitrogen atom and the carbon at the β position are each connected with a phenyl group. This structure has a certain space complexity due to multiple substituents, and each substituent has an important influence on its physical and chemical properties, such as fluorine atoms enhance lipophilicity, and carbonyl and phenyl
What are the main uses of 4-Fluoro-alpha - (2-Methyl-1-Oxopropyl) -Y-Oxo-N, β-Diphenylbenzene Butaneamide
4-Fluoro-alpha- (2-methyl-1-oxopropyl) -gamma-oxo-N, beta-diphenylphenylbutylamide, which has a wide range of uses.
In the field of pharmaceutical research and development, it may be used as a key intermediate. Due to its unique structure and specific chemical activity and spatial configuration, it can be combined with other compounds through a series of chemical reactions to construct complex molecular structures with specific pharmacological activities. It can help develop new drugs for specific diseases or optimize the efficacy and safety of existing drugs. For example, for some inflammation-related diseases, it is hoped that drugs with stronger anti-inflammatory effects and fewer side effects can be prepared through delicate synthesis steps using this material as a starting material.
In the field of materials science, it also shows potential value. Due to its unique characteristics of intermolecular forces and chemical stability, it may be applied to the development of new polymer materials. For example, introducing it into the structure of polymers may improve the mechanical properties, thermal stability or optical properties of materials. Additives containing the structure of this material in plastic products can enhance the toughness and temperature resistance of plastics, and broaden their application range in high temperature environments.
In addition, in the academic research of organic synthetic chemistry, it is often used as a model compound. By exploring various reactions, researchers can deeply explore the reaction mechanism and optimize the reaction conditions, providing an important reference for the development of organic synthesis methodologies. By studying the reaction characteristics of it with different reagents, novel reaction pathways and synthesis strategies can be discovered, which can promote the progress of theory and practice in the field of organic chemistry.
What are the physical properties of 4-Fluoro-alpha - (2-Methyl-1-Oxopropyl) -Y-Oxo-N, β-Diphenylbenzene Butaneamide
4 - Fluoro - α - ( 2 - Methyl - 1 - Oxo propyl ) - γ - oxo - N, β - Diphenylbenzene Butaneamide, which is an organic compound. Its physical properties are quite critical and are related to applications in many fields.
Looking at its properties, under room temperature and pressure, or in a solid state, it is mostly white or white-like crystalline powder. This form makes it relatively stable during storage and transportation, and is not easy to be lost due to the variability of the morphology.
When it comes to the melting point, the melting point of this compound may be in a specific temperature range. The melting point is an inherent property of the substance, which is of great significance for the identification and purification of this compound. By measuring the melting point, its purity can be judged. If the melting point deviates from the theoretical value, or it implies that it contains impurities.
In terms of solubility, it varies in different solvents. In organic solvents such as ethanol and acetone, it may have a certain solubility, which is convenient for it to be separated and purified as a reactant or product in organic synthesis reactions. In water, its solubility may be low, which is related to the molecular structure of the compound. The molecule contains more hydrophobic groups, resulting in poor hydrophilicity.
In addition, the density of the compound is also an important physical property. The value of the density is clearly defined by the volume and mass relationship it occupies in the solution. In actual production and experimental operations, accurate knowledge of the density can accurately control the dosage.
Its boiling point cannot be ignored. Under a specific pressure environment, when it reaches the boiling point, the compound changes from liquid to gaseous state. This property plays a significant role in separation technologies such as distillation, and it can be separated from other substances according to the difference in boiling point.
In short, 4 - Fluoro - α - ( 2 - Methyl - 1 - Oxo propyl ) - γ - oxo - N, β - Diphenylbenzene Butaneamide Many physical properties, such as properties, melting point, solubility, density and boiling point, are of great value to its research, production and application, providing a key basis for related work in the field of organic chemistry.
What is the synthesis method of 4-Fluoro-alpha - (2-Methyl-1-Oxopropyl) -Y-Oxo-N, β-Diphenylbenzene Butaneamide
To prepare 4 - Fluoro - α - ( 2 - Methyl - 1 - Oxo propyl ) - γ - Oxo - N, β - Diphenylbenzene Butaneamide, the method is as follows:
First take an appropriate amount of benzene derivatives, with specific reaction conditions, so that fluorine atoms are introduced into the benzene ring to obtain fluorine-containing benzene intermediates. This process requires temperature control and timing to ensure that fluorine atoms are accurately connected to the predetermined position.
Then, the fluorobenzene intermediate and the appropriate ketone compound are combined under the reaction principle of alkali catalysis, and the two are combined to form a product with a specific carbon chain and carbonyl structure. This product is an intermediate with the structure of alpha - (2-Methyl-1-Oxopropyl). During the reaction, the amount of base and the pH of the reaction system should be paid attention to to to avoid side reactions. After
, the intermediate is mixed with the phenethylamine compound in a suitable solvent, and a condensing agent is added to promote the formation of amide bonds, thereby constructing the N, β-Diphenyl structural part. The choice of solvent is crucial, and the effect on the solubility of the reactants and the reaction process needs to be considered.
Finally, a series of purification operations are carried out on the product, such as recrystallization, column chromatography, etc. During recrystallization, a suitable solvent is selected, and the difference in solubility between the product and the impurities in the solvent at different temperatures is used to precipitate the product and achieve the purpose of purification. Column chromatography realizes separation and purification according to the distribution coefficient of the product and the impurities between the stationary phase and the mobile phase. Finally, 4-Fluoro - α - ( 2-Methyl-1-Oxo propyl ) - γ - Oxo-N, β-Diphenylbenzene Butaneamide. Throughout the synthesis process, the conditions of each step of the reaction must be precisely controlled, and the structure and purity of each intermediate must be tested and confirmed before the next step of the reaction can be carried out to ensure the smooth synthesis of the target product.
What is the safety of 4-Fluoro-alpha - (2-Methyl-1-Oxopropyl) -Y-Oxo-N, β-Diphenylbenzene Butaneamide
This 4 - Fluoro - α - ( 2 - Methyl - 1 - Oxo propyl ) - γ - Oxo - N, β - Diphenylbenzene Butaneamide, is also an organic compound. However, its safety cannot be ignored and needs to be investigated in detail.
Discussing safety, first look at its toxicity. The toxicological properties of this compound are related to the health of organisms. If it enters the body, or interacts with biological macromolecules such as proteins and nucleic acids, it disrupts normal physiological functions. Or at the cellular level, it affects cell metabolism, proliferation and apoptosis, causing cell damage and even body diseases.
Then talk about its environmental safety. If this substance flows into the environment, in soil, water, atmosphere, or experiences complex physical, chemical, and biological processes. In soil, it may affect the structure and function of soil microbial community, destroying soil ecological balance; in water, it may endanger aquatic organisms, interfering with the material cycle and energy flow of aquatic ecosystems; in atmosphere, if it is volatile, or participates in atmospheric chemical reactions, affecting air quality.
Its stability is also tested. The interaction between atoms and groups in its chemical structure determines its stability under different conditions. If it is unstable, it is prone to decomposition, isomerization and other reactions, and the safety of the product also needs to be considered. And stability affects its existence, morphology, migration and transformation in the environment and organisms.
The preparation and use process also involves safety. During preparation, the raw materials used, the reaction conditions or the risks. High temperature, high pressure, toxic and harmful raw materials, etc., can cause safety accidents. During use, the operator is improperly protected, or the contact hazard is caused.
In summary, the safety of Ximing 4 - Fluoro - α - ( 2 - Methyl - 1 - Oxo propyl ) - γ - Oxo - N, β - Diphenylbenzene Butaneamide needs to be studied in detail in terms of autotoxicity, environmental impact, stability and operation process to ensure the safety of human health and ecological environment.