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What is the chemical structure of 4-Fluoro-α [2-Methyl-1-Oxopropyl] -γ-Oxo-N, β-Diphenylbenzene Butanamide
This is the chemical structure analysis of 4-fluoro - α - [ 2-methyl-1-oxopropyl ] - γ - oxo-N, β-diphenylphenylbutylamide. The name of this compound is long and complex, and its structure can be gradually analyzed according to its naming rules.
"4-fluorine" means that there are fluorine atoms connected at a specific position in the benzene ring, that is, at the No. 4 position. " Alpha - [2-methyl-1-oxopropyl] ", indicating that at the α position, there is a 2-methyl-1-oxopropyl substituent connected, which is a propyl structure containing methyl and carbonyl.
" γ-oxo ", indicating that there is a carbonyl group at the γ position." N, β-diphenyl "means that the nitrogen atom (N) and the β position are connected with phenyl groups, respectively." Phenylbutylamide "reveals that the main body of this compound is a structure of benzene ring connected to butylamide, and butylamide is formed by the combination of butyryl and amino group.
In summary, the structure of this compound consists of a benzene ring as the core, with fluorine atom substitution at position 4, a specific propyl substituent at position α, carbonyl at position γ, and phenyl at nitrogen atom and β position respectively, forming the basic structure of phenylbutylamide as a whole. Such a complex structure determines its unique chemical properties and possible chemical reactivity. In the field of organic chemistry, the research of such compounds may be of great significance for the development of new drugs, materials science, etc.
What are the main uses of 4-Fluoro-α [2-Methyl-1-Oxopropyl] -γ-Oxo-N, β-Diphenylbenzene Butanamide
4 - Fluoro - α - [ 2 - Methyl - 1 - Oxo propyl ] - γ - Oxo - N, β - Diphenylbenzene Butanamide, which is an organic compound. It has a wide range of uses in the field of medicine and is often used as a key intermediate for drug research and development. For example, in the creation of some anti-inflammatory drugs, its structural properties can interact with specific inflammation-related targets in the body. After reasonable modification and optimization, it may be able to obtain high-efficiency and low-toxicity anti-inflammatory drugs, bringing good news to patients with inflammatory diseases.
In the field of materials science, this compound may participate in the synthesis of polymer materials due to its unique molecular structure. With its polymerization with other monomers, it imparts novel properties to the material, such as improving the thermal stability and mechanical properties of the material, so that the material can be applied in high-end fields such as aerospace and electronic devices.
In organic synthesis chemistry, it is an important building block for building complex organic molecules. Chemists can use its specific functional groups to carry out various organic reactions, realize the total synthesis of complex natural products or organic compounds with special functions, promote the development of organic synthesis chemistry, and lay the foundation for the creation of new substances.
Furthermore, in biological activity research, it can be used as a lead compound. By studying its interaction mechanism with biomacromolecules, researchers can gain a deeper understanding of the physiological and pathological processes in vivo, providing theoretical basis and material basis for the development of new therapeutic drugs, biological probes, etc., which is of great significance for basic research in life sciences and the development of new drugs.
What are the physical properties of 4-Fluoro-α [2-Methyl-1-Oxopropyl] -γ-Oxo-N, β-Diphenylbenzene Butanamide
4 - Fluoro - α - [ 2 - Methyl - 1 - Oxo propyl ] - γ - oxo - N, β - Diphenylbenzene Butanamide, which is an organic compound whose physical properties are worth exploring.
Its appearance is often crystalline solid. This is due to the strong interaction forces between molecules, such as van der Waals forces and hydrogen bonds, which promote the orderly arrangement of molecules, resulting in the formation of a crystalline structure. Its color may be white to light yellow, which may be due to specific electron transitions and absorption spectral characteristics in the molecular structure.
In terms of melting point, due to the relatively complex molecular structure of the compound and the strong intermolecular forces, the melting point is relatively high. This property is due to the close arrangement and interaction between molecules, which requires high energy to destroy the lattice structure and convert the solid state into a liquid state.
In terms of solubility, the compound exhibits a certain solubility in organic solvents, but poor solubility in water. This is because its molecular structure is rich in non-polar benzene rings and alkyl groups, which are quite different from water molecules in polarity. According to the principle of "similar miscibility", the solubility in polar water is not good. In organic solvents such as ethanol and chloroform, the solubility is improved due to the formation of appropriate intermolecular interactions.
In addition, the density of the compound is also closely related to the molecular structure. Because the molecule contains atoms with relatively large atomic mass such as fluorine and oxygen, and the structure is relatively compact, the density may be relatively high.
The physical properties of the compound, such as appearance, melting point, solubility and density, are determined by its unique molecular structure, and have a key impact on its application in chemical synthesis, materials science and other fields.
What is the synthesis method of 4-Fluoro-α - [2-Methyl-1-Oxopropyl] -γ-Oxo-N, β-Diphenylbenzene Butanamide
To prepare 4-fluoro - α - [ 2-methyl-1-oxopropyl ] - γ - oxo-N, β-diphenylphenylbutylamide, the following ancient method can be used:
First take an appropriate amount of fluorobenzene derivatives and place them in a clean reactor. Nitrogen must be used to replace air in the kettle to create an inert atmosphere to prevent impurities from interfering with the reaction. Fluorobenzene derivatives are reaction starting materials, and the fluorine atoms in their structures have a profound impact on the subsequent reaction process and product characteristics.
Prepare another 2-methyl-1-oxopropyl-related reagent, and slowly drop it into the reactor under low temperature stirring. This process requires strict control of temperature and dripping speed, and the temperature should be maintained in a specific low temperature range to prevent side reactions from breeding. If the dripping speed is too fast, the reaction may be too violent, resulting in impure products; if it is too slow, it will take too long and affect the efficiency.
After the dripping is completed, gradually raise the temperature to a suitable reaction range and continue to stir. At this stage, the interaction between molecules is complex, and chemical bond breaking and recombination are parallel. A specific catalyst is added in a timely manner to promote the reaction rate. The amount and activity of the catalyst must be precisely controlled. Excessive or excessive activity may cause the reaction to go out of control; if insufficient, the reaction will be slow and difficult to achieve expectations.
When the reaction reaches a certain level, a reactant containing γ-oxo-N, β-diphenyl structures is introduced. When this reactant is added, the reaction system environment needs to be finely regulated, and factors such as pH and temperature cannot be ignored. pH imbalance, or reaction stagnation; temperature deviation, or product structure variation.
During the follow-up reaction process, a variety of monitoring methods, such as thin-layer chromatography, spectral analysis, etc., are required to gain insight into the progress of the reaction and determine the end point of the reaction. After reaching the end point, the reaction mixture is poured into a specific separation medium, and the impurities are removed by extraction, column chromatography and other separation and purification methods to obtain pure 4-fluoro - α - [ 2-methyl-1-oxypropyl ] - γ - oxo-N, β-diphenylphenylbutylamide products. Every step needs to be careful, the difference is exact, or the product is thousands of miles away.
4-Fluoro-α [2-Methyl-1-Oxopropyl] -γ-Oxo-N, β-Diphenylbenzene Butanamide What are the precautions during use
4 - Fluoro - α - [ 2 - Methyl - 1 - Oxo propyl ] - γ - oxo - N, β - Diphenylbenzene Butanamide is an organic compound. During use, many matters need to be paid attention to.
This compound has specific chemical activity, and it must be stored in a dry and cool environment. Because it is sensitive to humidity and temperature, humid or high temperature environments can easily cause it to deteriorate, affecting its quality and performance. For example, if placed in a hot and humid place, chemical reactions may occur, changing its chemical structure, and then its original efficacy will be greatly reduced.
When using and operating, protective measures are indispensable. It is necessary to wear suitable protective equipment, such as laboratory clothes, gloves and goggles. Because it may cause irritation to the skin, eyes and respiratory tract, if inadvertently contacted, it may cause discomfort or even damage. If not wearing gloves for direct contact, it may cause skin allergies, redness and swelling and other symptoms.
Furthermore, the place of use should be well ventilated. When the compound is used, it may evaporate harmful gases. Good ventilation can discharge harmful gases in time, reduce the concentration of harmful substances in the air, and protect the health of users. If the ventilation is poor, harmful gases will accumulate, which will be easily inhaled by the human body and endanger the respiratory system.
At the same time, the use process should be strictly operated according to the standard process. Precisely control the dosage and reaction conditions. Due to differences in dosage and reaction conditions, different reaction results may be caused, or even dangerous. For example, the reaction temperature is not properly controlled, or the reaction is out of control, causing a safety accident.
In addition, the waste after the compound is used cannot be discarded at will, and it needs to be properly disposed of according to regulations. Due to its certain toxicity and environmental hazards, improper disposal will pollute the environment. Relevant environmental regulations should be followed and appropriate disposal methods should be selected to reduce the negative impact on the environment.