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4-Fluoro-2-Iodo-1-Methylbenzene

4-Fluoro-2-Iodo-1-Methylbenzene

Hongda Chemical

Specifications

HS Code

219293

Chemical Formula C7H6FI
Molecular Weight 220.025 g/mol
Appearance Colorless to light yellow liquid
Boiling Point Around 197 - 199 °C
Density Around 1.77 g/cm³
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Flash Point Around 77 °C
Vapor Pressure Low at room temperature
Stability Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 4-Fluoro-2-Iodo-1-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 mL of 4 - fluoro - 2 - iodo - 1 - methylbenzene in a sealed glass bottle.
Storage 4 - fluoro - 2 - iodo - 1 - methylbenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent evaporation and contact with air or moisture. Store it separately from oxidizing agents and incompatible substances to avoid potential reactions. Label the storage container clearly for easy identification.
Shipping 4 - fluoro - 2 - iodo - 1 - methylbenzene is shipped in well - sealed, corrosion - resistant containers. They are carefully packed to prevent breakage. Shipment adheres to strict chemical transportation regulations to ensure safety during transit.
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4-Fluoro-2-Iodo-1-Methylbenzene 4-Fluoro-2-Iodo-1-Methylbenzene
General Information
Historical Development
The wise men of ancient times studied chemical things and often sought the rise and replacement of various things. In 4-Fluoro-2-Iodo-1-Methylbenzene, there is also a history of evolution. In the past, chemistry was not developed, and many people did not know about this substance. As science gradually flourished, the wise men worked hard to explore the physical properties. At the beginning, the preparation was difficult, and it was only occasionally obtained in the laboratory. However, the determination of scholars was unremitting, and after years of hard work, they studied the method of preparation, and the process became more and more exquisite. As a result, the output was gradually increased, and the application was also wide. In the field of medicine, it is a raw material for making good medicines; in the world of materials, it is possible to add new qualities. Looking at its development, it has come to light from the end, all thanks to the efforts of the wise men, so that this chemical substance can be used by the world and become the grand concept it is today.
Product Overview
4 - Fluoro - 2 - Iodo - 1 - Methylbenzene is also an organic compound. Among its molecular structures, above the benzene ring, the fluorine atom occupies the 4th position, the iodine atom occupies the 2nd position, and the methyl group occupies the 1st position. This compound has unique physical and chemical properties. Its appearance may be a colorless to slightly yellow liquid, with a certain degree of volatility. In chemical reactions, the presence of fluorine, iodine and methyl gives it special reactivity. Fluorine atoms have high electronegativity, which can affect the electron cloud density distribution of benzene rings; iodine atoms are large in size, but they are good leaving groups, which makes the compound active in reactions such as nucleophilic substitution. Methyl has a donator effect on benzene rings, which further affects its reaction characteristics. In the field of organic synthesis, 4 - Fluoro - 2 - Iodo - 1 - Methylbenzene is often used as an important intermediate, which can be converted into various higher-value organic compounds through various chemical reaction pathways. It has potential applications in drug development, materials science and many other fields.
Physical & Chemical Properties
4 - Fluoro - 2 - Iodo - 1 - Methylbenzene is an organic compound, and its physicochemical properties are particularly important. Looking at its physical properties, it is mostly liquid at room temperature, with a special odor and high volatility. This is due to the relatively weak intermolecular force, which makes it volatile. Its density is slightly larger than that of water, and it is difficult to dissolve in water, because the compound has strong hydrophobicity.
On chemical properties, due to the presence of halogen atoms such as fluorine and iodine, the chemical activity is high. Fluorine atoms have strong electronegativity, which changes the density distribution of electron clouds in the benzene ring, making it more prone to electrophilic substitution reactions. Iodine atoms can participate in nucleophilic substitution and other reactions under appropriate conditions, providing the possibility for the synthesis of new compounds. The physicochemical properties of 4 - Fluoro - 2 - Iodo - 1 - Methylbenzene lay the foundation for its application in organic synthesis, drug development and other fields.
Technical Specifications & Labeling
4 - Fluoro - 2 - Iodo - 1 - Methylbenzene is an organic compound. Its preparation process is very critical and requires specific chemical principles and operating procedures. First of all, the selection and treatment of raw materials is of paramount importance. The selected raw materials should have high purity and suitable chemical properties. During the reaction process, parameters such as temperature, pressure and reaction time need to be precisely controlled. If the temperature is too high or too low, it may cause abnormal reaction rate, affecting the purity and yield of the product. The pressure also needs to be maintained within an appropriate range to ensure the smooth progress of the reaction. Standard identification of
products is also indispensable. Modern analytical methods such as nuclear magnetic resonance and mass spectrometry can be used to confirm its structure and purity. By accurately measuring its physical and chemical properties, such as melting point, boiling point, etc., and comparing with the standard data, determine whether the product meets the standard. Strictly follow this technical specification and standard identification (product parameters) to ensure the quality and application efficiency of 4-Fluoro-2-Iodo-1-Methylbenzene.
Preparation Method
This product is 4 - Fluoro - 2 - Iodo - 1 - Methylbenzene, and the raw materials are prepared first. Fluorobenzene, iodomethane, potassium iodide, etc. are taken as the base materials. The preparation process involves first using fluorobenzene and iodomethane in a special container, adding a catalyst, controlling the temperature at about 60 degrees, and performing a nucleophilic substitution reaction. When the reaction is completed, it is cooled to room temperature, washed with water, and the unreacted iodomethane and impurities are removed.
Then, potassium iodide is added, and the temperature is raised to 80 degrees, and then the reaction is carried out, so that the fluorine atom of the fluorobenzene is replaced by the iodine atom. After the reaction is completed, it is extracted with an organic solvent, and the
In this preparation process, temperature control, time control and catalyst dosage are all key. Each reaction step needs to be carried out in sequence and not disturbed to obtain pure 4-Fluoro-2-Iodo-1-Methylbenzene.
Chemical Reactions & Modifications
There is a chemical substance today, named 4 - Fluoro - 2 - Iodo - 1 - Methylbenzene, and its chemical reaction and modification are of great importance to our generation. Looking at this substance, we want to understand the law of its reaction, explore the method of modification, and increase its usefulness.
Past research has gained some understanding. In a specific environment, it can interact with other things, and it can cause chemical changes. However, there may be something wrong with this reaction, the rate is not fast, and the yield is not abundant. In order to improve, we must think about changes.
You can try to change the conditions of the reaction, adjust the temperature and pressure, and observe its response. Or find a new type of catalyst to change the speed and make the reaction smoother. Or change its structure, fine-tune the group, and observe the transition of its properties. In this way, it may promote the excellent reaction of this substance, improve its performance, and be more widely used in industry and scientific research. In the hope that our research can make this chemical substance more powerful and used by the world.
Synonyms & Product Names
4 - Fluoro - 2 - Iodo - 1 - Methylbenzene, this substance is also known to our chemical researchers by its synonym and trade name. Although the ancient books of Guanfu did not directly describe this substance, it can be deduced from its chemical properties and structural characteristics.
In the past, the naming method of chemical substances was either based on their origin or according to their properties. Today's 4 - Fluoro - 2 - Iodo - 1 - Methylbenzene, because of its fluorine (fluoro), iodo (iodo) and methyl (methyl) on the benzene (benzene), hence the name. The different names may vary depending on the region and the research. As for the trade name, the merchant may set up another name to highlight its characteristics and uses.
When I am studying, I should carefully investigate the different names and trade names to avoid confusion. Cover different names, or lead to the same thing, and understand this, it will be beneficial to the research and application of chemistry. In this way, it will live up to our original intention of studying chemical things and exploring their mysteries.
Safety & Operational Standards
4 - Fluoro - 2 - Iodo - 1 - Methylbenzene Safety and Operation Specifications
F 4 - Fluoro - 2 - Iodo - 1 - Methylbenzene, a commonly used reagent for organic synthesis. In all aspects of its experimental operation and storage, it is necessary to abide by safety regulations to avoid accidents.
Looking at its physical and chemical properties, this compound has a specific melting point and chemical activity. Therefore, when storing, it should be placed in a cool, dry and well ventilated place. Its container must be sealed to prevent moisture and air from interfering and causing it to deteriorate.
During operation, the first protection. The experimenter should wear appropriate protective clothing, such as laboratory clothes, gloves and goggles. Because the compound may be irritating to the skin and eyes, if you come into contact with it, rinse it with plenty of water immediately and seek medical attention according to the situation.
Furthermore, the operation should be carried out in a fume hood. This compound may evaporate harmful gases, and good ventilation can reduce its concentration in the air to ensure the health of the experimenter. When taking it, use clean and precise equipment, and take more or less according to the required amount of the experiment to avoid waste and danger.
Mixing or reaction steps must follow established procedures. Be familiar with the characteristics of its reaction with other substances, and control the temperature and speed to prevent violent reactions or out of control. If the reaction generates heat, a cooling device should be prepared; if the gas is produced, the export and collection of the gas should be taken into account to avoid excessive pressure.
After the experiment, properly dispose of the remaining 4-Fluoro-2 - Iodo-1 - Methylbenzene and related wastes. Do not dump at will. According to the regulations of chemical waste treatment, collect them in categories and hand them over to professional institutions for disposal to ensure environmental safety.
In short, the use of 4-Fluoro-2 - Iodo-1 - Methylbenzene, from storage to operation, every step is related to safety. Experimenters should strictly abide by the regulations and be careful to avoid danger and complete the experiment smoothly.
Application Area
4 - Fluoro - 2 - Iodo - 1 - Methylbenzene is an organic compound with a wide range of application fields. In the field of medicinal chemistry, due to its unique chemical structure, it can be used as a key intermediate to help synthesize drug molecules with specific biological activities, or to show therapeutic effects on certain diseases. In the field of materials science, this compound may participate in the creation of new functional materials, such as materials with special optical and electrical properties, bringing new opportunities for electronic devices, optical devices and other fields. In organic synthetic chemistry, it is an important raw material that can use various chemical reactions to construct more complex organic molecular structures, expand the types and functions of organic compounds, and thus promote the development of organic synthetic chemistry.
Research & Development
Today there is a thing called 4 - Fluoro - 2 - Iodo - 1 - Methylbenzene. I am a chemical researcher and have been studying it for many years.
This physicality is the key. Its structure is unique, fluorine, iodine and methyl each live in a specific position in the benzene ring, and interact, resulting in different characteristics. After repeated tests, the reaction situation of the reaction is carefully observed, and under different conditions, the changes are observed.
Study the method of its preparation, and strive to improve. The initial method may take a long time, or the yield is not ideal. Then I dedicated myself to studying, consulting ancient books and modern books, learning from the strengths of various schools, and improving the process. After repeated attempts, a better path has been found, resulting in improved yield and better quality.
Looking to the future, this substance may have great uses in many fields. On top of medicine, it may be the basis for creating new drugs; among materials, it may add the nature of new materials. I should make unremitting research, hoping to expand its use, and gain benefits for both academia and industry, promoting the research and development of this substance, reaching a new level.
Toxicity Research
Today there is a thing called 4 - Fluoro - 2 - Iodo - 1 - Methylbenzene, and we want to study toxicology. The toxicity of this substance is related to the health of people's livelihood and cannot be ignored.
To study its properties in detail, it needs to be tested many times. Observe its reaction in various media and observe its effect on biological organisms. Or take a small amount and apply it to insects to observe their behavior and physiological changes; or use it to plants and trees, depending on their growth and withering state.
After many inquiries, we can know the strength of its toxicity and the mechanism of its action. If the toxicity is very strong, it should be strictly controlled to prevent it from dispersing, so as not to harm the living beings. If the toxicity is slightly slowed down, it should not be slack off. It must be recorded in detail to provide detailed evidence for future use, so that the substance can be used where it is available and properly without causing harm.
Future Prospects
Wuguan 4 - Fluoro - 2 - Iodo - 1 - Methylbenzene is unique in its properties and has potential in the field of chemistry. Although it is only visible at the moment, I look forward to the future, and it may emerge in the creation of medicine. Due to its exquisite structure, it may be able to accurately meet the needs of pharmacology, making it a good prescription for treating diseases.
It may also shine in the development of materials. Its molecular structure may endow materials with novel characteristics, such as excellent electrical conductivity, heat insulation and other properties, making materials useful in the field of high-tech.
Let's take the road ahead and explore the difficulties, but I firmly believe that with time and unremitting research, we will be able to tap its endless potential, open up a new world, and draw a magnificent chapter for the development of chemistry, so as to open up the future.
Where to Buy 4-Fluoro-2-Iodo-1-Methylbenzene in China?
As a trusted 4-Fluoro-2-Iodo-1-Methylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Fluoro-2-Iodo-1-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-fluoro-2-iodine-1-methylbenzene?
In "Tiangong Kaiwu", the main uses of aminonitrile are related to many fields. It is very important in chemical synthesis. It can be used as a key raw material for the preparation of various nitrogen-containing compounds. Due to its structure containing cyano and amino groups, the cap has unique chemical activity and can participate in various chemical reactions, resulting in the generation of many organic intermediates. It is of great significance in the preparation of medicine, pesticides and dyes.
Taking the field of medicine as an example, aminonitrile can be made into specific pharmaceutical ingredients through a series of delicate transformations. It can introduce key nitrogen atom groups into drug molecules, change the chemical properties and physiological activities of drugs, and help to develop better and more targeted drugs.
In the creation of pesticides, aminonitrile is also an indispensable raw material. By means of chemical synthesis, it can be converted into pesticide products with high insecticidal, bactericidal or herbicidal properties. Due to the special structure of aminonitrile, it can endow pesticides with a unique mechanism of action, improve the control effect on pests, and have a relatively small impact on the environment.
In the dye industry, aminonitrile can participate in the synthesis of dyes with bright colors and good stability. By reacting with other organic compounds, special chromophore groups are constructed to make dyes show rich colors and meet the diverse needs of textile, printing and dyeing industries.
Furthermore, aminonitrile has also emerged in the field of materials science. After appropriate modification and polymerization, polymer materials with special properties can be prepared, such as high-strength, high-toughness or functional polymers, which are used in high-end fields such as aerospace and automobile manufacturing.
What are the physical properties of 4-fluoro-2-iodine-1-methylbenzene?
What are the physical properties of 4-Jiang-2-Question-1-aminonaphthalene? This imitation of "Tiangong Kaiwu" answers this question in ancient words.
Aminonaphthalene is one of the organic compounds. Its properties are mostly crystalline or powder-like under normal circumstances. Looking at its color, it is often white to light yellow, and the color is plain.
When it comes to melting point, aminonaphthalene has a specific value. The number of its melting points varies depending on the position of the amino group on the naphthalene ring. For example, α-aminonaphthalene has a high melting point, between hundreds of degrees. This characteristic makes it melt from solid to liquid under moderate temperature.
As for solubility, the solubility of aminonaphthalene in water is quite small. Water is a common solvent, but aminonaphthalene has a poor affinity with it and can only dissolve slightly. However, in organic solvents, such as ethanol and ether, its solubility is greatly improved. The molecular structure of organic solvents such as ethanol and ether is compatible with aminonaphthalene, so aminonaphthalene can be more easily dissolved in them, or form a uniform solution.
Its density is also an important physical property. The density of aminonaphthalene is slightly different from that of water. Measured by mass per unit volume, its value is obtained according to the standard measurement method, and it is also different from the density of naphthalene and other related derivatives. This difference reflects the effect of molecular structure and composition on density.
Furthermore, aminonaphthalene has a certain degree of volatility. Although it is not as easy to escape as common volatile substances, under certain conditions, such as higher temperatures or prolonged exposure to air, some molecules will escape from the solid or liquid surface and escape into the gas phase.
The physical properties of aminonaphthalene, such as color, state, melting point, solubility, density and volatility, are determined by its unique molecular structure, and play a key role in its application and reaction in many chemical and industrial fields.
Is 4-fluoro-2-iodine-1-methylbenzene chemically stable?
The chemical properties of 4-Jiang-2-Question-1-methylpyridine are stable?
The chemical properties of methylpyridine are quite stable in many situations. Methylpyridine contains nitrogen heterocycles, and the conjugated structure of the ring endows it with certain stability. This conjugate system makes the electron cloud distributed evenly, enhances the stability of the molecule, and is not easily disturbed by ordinary external factors.
And the methyl group is attached to the pyridine ring. Although the methyl group has a certain electron-giving effect, it does not have a severe impact on the overall stability of the pyridine ring. Under common temperature and pressure conditions, without the action of extreme reagents such as strong oxidants, strong acids or strong bases, methyl pyridine can maintain its own structure and properties unchanged.
For example, in room temperature and neutral environments, methylpyridine can be stored for a long time without significant chemical reactions. It can resist the slow oxidation of oxygen in the air, and does not easily react with water such as hydrolysis. Even in the case of general organic solvents, it is only physically mixed, and there are few chemical changes.
However, it is not said that the chemical properties of methylpyridine are absolutely stable. In the case of strong oxidizing agents, such as acidic potassium permanganate solution, the side chain methyl of the pyridine ring may be oxidized to form corresponding carboxylic acid derivatives. In the case of strong acids or bases, protonation or nucleophilic substitution can occur due to the presence of nitrogen atoms, indicating that its stability is limited under specific conditions.
In summary, the chemical properties of methylpyridine are relatively stable under conventional conditions, but in specific chemical environments, they will also exhibit chemical activity and react.
What is the preparation method of 4-fluoro-2-iodine-1-methylbenzene?
To prepare 4-hydroxy-2-ketone-1-methylindole, the method is as follows:
First take an appropriate amount of raw materials and mix them in a specific ratio. Wash and dry the reaction vessel to ensure that there is no impurity interference. Measure 2-methylindole with a clean instrument and place it in the reactor. This is the starting material of the reaction. Its purity is related to the quality of the final product, so it is necessary to choose carefully.
Then, slowly add reagents that can cause 4-hydroxylation and 2-ketonation. When adding reagents, pay attention to the speed, not too fast, to prevent the reaction from being too violent and out of control. In this process, temperature control is crucial. Maintaining a suitable temperature range allows the reaction to proceed in the desired direction. Use a warm fire and slow heat to gradually heat up the reaction system, and closely observe the signs of the reaction, such as color changes and bubble formation.
During the reaction process, stirring is also indispensable. Stir at a constant speed to fully contact the reactants to accelerate the process of the reaction and ensure that the reaction is uniform. When the reaction proceeds to a certain extent, specific detection methods, such as thin-layer chromatography, can be used to monitor the progress of the reaction and determine whether the reaction has reached the expected level.
After the reaction is completed, the product is separated and purified. The reaction mixture is first dissolved in a suitable solvent, and the impurities are removed by multiple extraction, filtration and other steps by taking advantage of the difference in solubility of different substances in the solvent. Subsequently, the product is further purified by distillation or recrystallization until the purity of the product meets the requirements. In this way, a relatively pure 4-hydroxyl-2-one-1-methylindole can be obtained for pharmaceutical or other purposes.
What are the precautions for storing and transporting 4-fluoro-2-iodine-1-methylbenzene?
4-Jiang-2-Question-1-Methylnaphthalene needs to pay attention to many key matters during storage and transportation.
Methylnaphthalene is flammable, and when storing, a cool and ventilated warehouse should be selected. The warehouse temperature should be controlled in a suitable range, away from fire and heat sources, and prevent direct sunlight. Because it is flammable in case of open fire and hot topic, the lighting and ventilation facilities in the warehouse must be explosion-proof, and the switch should be placed outside the warehouse. At the same time, it should be stored separately from oxidants and acids, and should not be mixed in storage to avoid danger caused by violent reactions.
In the transportation process, the transportation vehicle must be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. Summer transportation should be carried out in the morning and evening to prevent high temperature from volatilizing methylnaphthalene and increasing the danger. During transportation, exposure to sun, rain and high temperature should be protected. Vehicle exhaust pipes must be equipped with fire retardant devices, and mixed transportation with oxidants, acids, etc. is prohibited. During transportation, the speed of the vehicle should not be too fast, and it is not allowed to forcibly overtake the car to ensure smooth driving to prevent package damage due to bumps and collisions, which will cause methylnaphthalene leakage. When loading and unloading, it is necessary to pack and unload lightly. It is strictly forbidden to drop, heavy pressure and friction to avoid damage to the packaging container.
Transportation and storage personnel must undergo professional training and be familiar with the dangerous characteristics of methylnaphthalene, emergency treatment methods, etc. In the event of a leak, personnel from the leakage contaminated area should be Emergency personnel must wear self-contained positive pressure breathing apparatus and fire protection clothing. Cut off the source of leakage as much as possible to prevent it from flowing into restricted spaces such as sewers and drainage ditches. In the event of a small amount of leakage, it can be adsorbed or absorbed by sand or other non-combustible materials; in the event of a large amount of leakage, build a dike or dig a pit for containment, cover it with foam to reduce vapor disasters, and then transfer it to a tanker or a special collector with an explosion-proof pump for recycling or transportation to a waste treatment site for disposal. In this way, the safety of methylnaphthalene storage and transportation can be guaranteed to the greatest extent.