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4-Fluoro-2-Difluoromethoxynitrobenzene

4-Fluoro-2-Difluoromethoxynitrobenzene

Hongda Chemical

    Specifications

    HS Code

    231431

    Chemical Formula C7H3F3N2O4
    Molecular Weight 222.104
    Solubility Solubility in organic solvents like dichloromethane, toluene, etc. likely due to its organic nature; low solubility in water due to non - polarity of most of the molecule and hydrophobicity of the fluorinated and nitro groups
    Flash Point Unknown without experimental determination but relevant for handling in industrial or laboratory settings
    Vapor Pressure Low vapor pressure expected as it is a relatively large and polar organic molecule
    Stability Stable under normal conditions but can react under strong reducing or oxidizing conditions due to the nitro group

    As an accredited 4-Fluoro-2-Difluoromethoxynitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4 - fluoro - 2 - difluoromethoxynitrobenzene packaged in a sealed, chemical - resistant bottle.
    Storage 4 - fluoro - 2 - difluoromethoxynitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. It should be stored in a tightly sealed container to prevent leakage and exposure to air or moisture. Keep it separate from oxidizing agents, reducing agents, and other incompatible substances to avoid potential chemical reactions.
    Shipping 4 - fluoro - 2 - difluoromethoxynitrobenzene is shipped in well - sealed containers, following strict chemical transport regulations. Containers are designed to prevent leakage and ensure safe transit, with temperature and handling controls in place.
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    4-Fluoro-2-Difluoromethoxynitrobenzene 4-Fluoro-2-Difluoromethoxynitrobenzene
    General Information
    Historical Development
    4 - Fluoro - 2 - Difluoromethoxynitrobenzene is an important chemical compound in the field of chemical synthesis. At the beginning of its history, the academic community only knew the basic characteristics of this compound, the synthesis method was simple and crude, and the yield was low. However, over the years, it has been studied by countless talents. Advanced chemists have worked hard to improve the synthesis process, from the selection of raw materials to the control of reaction conditions. With the passage of time, the synthesis technology has gradually matured, the yield has been greatly improved, and the scope of application has been continuously expanded. Today, this compound plays a key role in many fields such as medicine and materials. The exploration process of the past has paved the way for the wide application of today.
    Product Overview
    4 - Fluoro - 2 - Difluoromethoxynitrobenzene is a unique chemical product. Its synthesis requires exquisite skills and harsh conditions. This product has unique chemical properties, and the introduction of fluorine atoms and difluoromethoxy groups gives it a different activity.
    When preparing, the choice of raw materials is crucial, and the reaction process also needs to be carefully controlled. Temperature, pressure, catalyst and other factors have a great impact on the purity and yield of the product.
    This product has great potential in many fields, or can be used to create new drugs. With its special structure, it is expected to produce unique effects on specific diseases; or it has emerged in the field of materials science, providing the possibility for the development of new functional materials. Its future application prospects are truly fascinating, and we urgently need to explore them in depth to make the best use of them.
    Physical & Chemical Properties
    4 - Fluoro - 2 - Difluoromethoxynitrobenzene is an important organic compound. Its physical properties are unique. It is mostly liquid at room temperature, and its color is nearly colorless and transparent. It is like clear water, with a slightly specific smell and a faint fragrance, but it is different from ordinary aroma.
    On chemical properties, among this compound, fluorine atoms, difluoromethoxy groups and nitro groups give it unique activity. Nitro groups are active and highly oxidizing, and are easy to participate in many chemical reactions, such as nucleophilic substitution reactions. The presence of fluorine atoms and difluoromethoxy groups enhances molecular stability and also changes the polarity of the compound, making it well soluble in organic solvents. And because of its special structure, it can undergo a variety of transformations under specific conditions, making it a key intermediate in the field of organic synthesis, such as the preparation of drugs and materials with special functions, which is like the key to opening the door to many wonderful chemical changes.
    Technical Specifications & Labeling
    4 - Fluoro - 2 - Difluoromethoxynitrobenzene is an important chemical product. Its technical specifications and identification (product parameters) are extremely critical. The purity of this product needs to reach a very high standard, and the impurity content should be strictly controlled in a very low range to ensure that its chemical properties are stable and suitable for various related reactions. Its appearance should show a specific color and shape as one of the quality labels. In terms of identification, basic parameters such as product name, chemical formula, molecular weight must be clearly marked, and safety warning labels are also indispensable to remind users to pay attention to latent risks. In technical specifications, physical parameters such as melting point and boiling point, as well as chemical parameters such as chemical reaction activity, are all important basis for measuring product quality, and are related to its effectiveness in practical applications.
    Preparation Method
    In order to make 4 - Fluoro - 2 - Difluoromethoxynitrobenzene, the raw materials and production process, reaction steps and catalytic mechanism are the key.
    The raw materials made by
    should be carefully selected. Based on specific halogenated aromatics, supplemented by fluorine-containing reagents, the two can be adapted to lay the foundation for the reaction. The production process requires precise temperature control, and a suitable pressure should be set in a specific reactor. The halogenated aromatics are first thrown in, followed by slow injection of fluorine-containing reagents, stirring evenly, so that the molecules are fully blended.
    The reaction step is to initially heat up to a moderate level, so that the activity of the raw materials increases, the molecules collide frequently, and the reaction starts. During this period, the reaction process is closely monitored, and the temperature and stirring rate are adjusted in a timely manner. When the reaction reaches a specific stage, it cools down and stabilizes the product structure.
    Catalytic mechanism, high-efficiency catalysts are selected to reduce the activation energy of the reaction and accelerate the reaction without consuming themselves. The catalyst activity check point adsorbs raw material molecules, making its structure change and easy to form new bonds. After this, it is expected to obtain high-purity 4-Fluoro-2-Difluoromethoxynitrobenzene products.
    Chemical Reactions & Modifications
    4 - Fluoro - 2 - Difluoromethoxynitrobenzene, it is also a chemical substance. Its transformation and reaction properties are important for our research.
    If you want to obtain this substance, it is often a chemical reaction. For example, starting with an aromatic compound, it is supplemented by fluorine-containing and methoxy-containing compounds, which can be substituted and reversed according to the appropriate degree and force. However, among the reactions, there are many that can be investigated.
    Its chemical properties are also interesting. The introduction of fluorine atoms and difluoromethoxy groups leads to the molecular properties and molecular cloud separation. This has implications for its physical rationality and chemical activity. Such as melting and boiling, solubility, and the appearance in the core and reaction are all different due to the change. We are looking for ways to understand the properties of its transformation, so as to make good use of it, and to explore new frontiers such as industrial materials research.
    Synonyms & Product Names
    4 - Fluoro - 2 - Difluoromethoxynitrobenzene, the product of chemistry is also. Looking at its name, we know that its structure is exquisite, fluorine, difluoromethoxy and nitro are on the benzene ring according to their positions, and interact with each other, giving this thing unique characteristics.
    In the field of chemical industry, the synonyms and trade names related to this thing are all symbols to identify this thing. Synonyms use different words to express the same essence, so that the academic community can communicate more smoothly. The trade name is the name named by the merchant when it is sold in the market, hoping to recognize its characteristics and attract the attention of customers.
    Such synonyms and trade names are either named according to their structural characteristics, or according to their uses and properties. In research and production, clarifying their synonyms and trade names can avoid confusion, facilitate the circulation of information and the inheritance of technology, and enable our generation to practice chemical synthesis and application more smoothly and explore deeper.
    Safety & Operational Standards
    4 - Fluoro - 2 - Difluoromethoxynitrobenzene Safety and Operating Specifications
    F 4 - Fluoro - 2 - Difluoromethoxynitrobenzene, chemical substances are also. Its preparation, storage, use of various links, safety and operating standards are the most important and must not be ignored.
    At the beginning of preparation, all raw materials and reagents must be inspected in detail to check their purity and properties, so as not to be worried. The utensils used must also be clean and intact to prevent impurities from mixing and causing the reaction to be biased. During the reaction process, the control of temperature, pressure and reaction time is crucial. It must be adjusted slowly according to the established program and cannot be ignored. If the temperature is too high, there is a risk of overreaction and explosion; if the pressure is inappropriate, the reaction will be difficult, or by-products will be caused.
    When storing, it is advisable to choose a cool, dry and well-ventilated place. Avoid direct sunlight and keep away from fire and heat sources. This substance may be corrosive or toxic, so the container must be corrosion-resistant and sealed to prevent leakage. Label clearly, stating its name, characteristics, hazards and emergency response methods.
    As for the use, the operator must wear suitable protective equipment, such as protective clothing, gloves, goggles, gas masks, etc., to ensure their own safety. When taking it, the action should be slow and do not spill it. If you accidentally touch it, you should quickly rinse it with a lot of water, and in severe cases, seek medical treatment. After use, the residue should not be disposed of at will, but must be properly disposed of in accordance with environmental protection regulations, so as to avoid polluting the environment.
    In short, 4-Fluoro-2-Difluoromethoxynitrobenzene Although it is used in chemical research, industrial production or has great use, its safety and operating standards are related to human life and the environment, and it should not be slack a little. Only by following the rules and doing it cautiously can the purpose of scientific research and production be achieved without worries.
    Application Area
    Today there is a product called 4 - Fluoro - 2 - Difluoromethoxynitrobenzene. This product is outstanding in various application fields.
    In the field of pharmaceutical synthesis, it can be a key intermediate. With exquisite chemical reactions, it can combine with other substances to form a new drug with good curative effect. This new drug may target difficult diseases and relieve the pain of patients.
    In the field of material research and development, its characteristics are also superb. It can participate in material synthesis and endow materials with unique properties, such as better stability, special optical properties, etc., opening up a wide range of new uses for materials.
    In the field of fine chemicals, with its own structure and properties, through ingenious craftsmanship, it can produce a variety of fine chemical products to meet the diverse needs of industry and life.
    Research & Development
    Today there is a product named 4 - Fluoro - 2 - Difluoromethoxynitrobenzene. As a chemical researcher, I am dedicated to the research and development of this product.
    At the beginning, analyze its structure, gain insight into its characteristics, and clarify its potential value in the field of chemistry. After months of research, I have explored many synthetic methods, hoping to obtain an efficient and pure production process.
    During the experiment, I have repeatedly encountered difficulties. The purity of raw materials and the conditions of reaction are all the keys to success or failure. However, with perseverance, I have tried repeatedly and adjusted the parameters. Finally, a method can increase its yield and improve its purity.
    Looking to the future, I hope to use this as a basis to expand the field of application of this product. Or for the development of new drugs, or to invest in material innovation. With unremitting efforts, we will contribute to the development of chemistry and make 4-Fluoro-2-Difluoromethoxynitrobenzene shine even more.
    Toxicity Research
    I am committed to the study of chemical properties, and recently focused on 4 - Fluoro - 2 - Difluoromethoxynitrobenzene agent. The toxicity of this agent is crucial.
    Detailed investigation of this agent, its molecular structure is unique, fluorine and nitro combination, or toxic changes. After various experiments, animal samples were used to observe its reaction. At first, the test animals were slightly tired, and then they slowed down and ate less. This is a sign of initial toxicity.
    After cell experiments, under a specific environment, the cell activity dropped sharply and the morphology also changed. From this point of view, 4 - Fluoro - 2 - Difluoromethoxynitrobenzene is quite toxic. Follow-up studies should focus on the root cause of toxicity and how to reduce its harm, so as to promote the rational use of this agent, avoid its harm and promote its benefits.
    Future Prospects
    Fu 4 - Fluoro - 2 - Difluoromethoxynitrobenzene, a new chemical substance. Looking at its structure, fluorine, difluoromethoxy and nitro are combined with benzene ring. This unique combination gives it specificity.
    In the future development, it may make great progress in the field of medical chemistry. Because of its special structure, it may be used as a key intermediate to create new drugs and fight various diseases. In materials science, it is also expected to emerge, contributing to the research and development of new functional materials.
    Although current research may have limitations, with time, when technology is refined and explored in depth, it will be able to explore more of its potential, create a new situation for human well-being and scientific progress, and develop a grand vision for the future.
    Where to Buy 4-Fluoro-2-Difluoromethoxynitrobenzene in China?
    As a trusted 4-Fluoro-2-Difluoromethoxynitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Fluoro-2-Difluoromethoxynitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Fluoro-2-Difluoromethoxynitrobenzene?
    4-Fluoro-2-difluoromethoxy-nitrobenzene is also an organic compound. It has a wide range of uses and plays an important role in the synthesis of medicine. To cover the process of pharmaceutical preparation, it is necessary to use it as a raw material, and after serialization, it can be turned into a drug molecule with a specific curative effect.
    It is also indispensable in the field of pesticide creation. With its special chemical structure and ingenious transformation, it can produce highly efficient and low-toxic pesticide products, and protect farmers against pests and diseases and ensure a good harvest.
    It is also useful in the field of material science. Or it can be used as a synthetic intermediate for special functional materials, so that the material has different properties, such as improving the stability and conductivity of the material, etc., to meet the needs of various industries.
    In addition, in the way of scientific research and exploration, this is often used as a reagent to help chemists explore new reaction mechanisms, develop new synthesis paths, expand the boundaries of chemical cognition, and open up new future technologies. This is what 4-fluoro-2-difluoromethoxy nitrobenzene does.
    What are the physical properties of 4-Fluoro-2-Difluoromethoxynitrobenzene?
    4-Fluoro-2-difluoromethoxy-nitrobenzene, this is an organic compound. Its physical properties are unique, let me explain in detail.
    Looking at its appearance, under room temperature and pressure, it is mostly colorless to light yellow liquid, clear and with a certain fluidity. This state is easy to mix evenly with other substances in many chemical reaction systems, laying the foundation for the smooth progress of the reaction.
    When it comes to smell, it emits a specific aromatic smell. Although it is not strong and pungent, it cannot be ignored. This smell can be used as a preliminary identification feature.
    Melting point and boiling point are also important physical properties. Its melting point is about a specific low temperature range, and the specific value varies depending on the precise measurement conditions. The boiling point is in a certain temperature range. When the temperature rises to the boiling point, the substance will change from liquid to gaseous state. With this characteristic, during the separation and purification of the substance, it can be effectively separated from other substances by means of distillation and other means according to the difference in boiling point.
    In terms of density, compared with water, 4-fluoro-2-difluoromethoxy nitrobenzene has a specific density value, which is generally greater than that of water, so it will sink to the bottom after mixing with water. This characteristic is of great significance in operations involving liquid-liquid separation.
    Solubility is also key. It exhibits good solubility in organic solvents such as ethanol, ethyl ether, dichloromethane, etc., and can be miscible with these organic solvents in any ratio. However, in water, the solubility is minimal and almost insoluble. This solubility characteristic, in the process of chemical synthesis and separation, can be selected according to different needs for extraction, reaction and other operations.
    In addition, the vapor pressure of the substance also changes accordingly at different temperatures. When the temperature increases, the vapor pressure increases, which means that in a higher temperature environment, the degree of volatilization increases. During storage and use, this factor needs to be fully considered to ensure the safety of operation and the stability of the substance.
    What is 4-Fluoro-2-Difluoromethoxynitrobenzene synthesis method?
    The synthesis of 4-fluoro-2-difluoromethoxy-nitrobenzene is an important topic in the field of organic synthesis. Its synthesis usually requires several steps, each step requires fine operation and suitable conditions.
    The choice of starting materials is very critical. Fluorobenzene-containing compounds are commonly used as the starting point, because the presence of fluorine atoms on the benzene ring can affect the activity and selectivity of subsequent reactions. If 4-fluoro-2-nitrophenol is used as the starting material, the phenolic hydroxyl group of this compound can be converted into difluoromethoxy through a specific reaction.
    To obtain difluoromethoxy, nucleophilic substitution is often used. The reaction of difluoromethyl halide with phenol salt can realize the transformation of phenolic hydroxyl group to difluoromethoxy group. In this process, a suitable base needs to be selected to promote the deprotonation of phenolic hydroxyl group and form active phenolic salt, so that the nucleophilic substitution reaction can proceed smoothly. The strength and dosage of the base need to be precisely controlled. If the base is too strong or excessive, or side reactions occur, the purity and yield of the product will be affected.
    In the nucleophilic substitution reaction, the reaction solvent also plays an important role. Aprotic polar solvents such as N, N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO) are often selected because they can dissolve the reactants, promote the ionization process, and increase the reaction rate. At the same time, the reaction temperature and time also need to be strictly controlled. If the temperature is too high or the time is too long, or the overreaction is triggered, unnecessary by-products are generated; if the temperature is too low or the time is too short, the reaction may be incomplete and the yield will be reduced.
    After the successful introduction of difluoromethoxy, the product needs to be separated and purified. Column chromatography or recrystallization method is commonly used to remove the residual impurities, unreacted raw materials and by-products in the reaction to obtain high-purity 4-fluoro-2-difluoromethoxy nitrobenzene. This synthesis method requires the experimenter to master the organic synthesis skills and precisely control the reaction conditions in order to efficiently synthesize the target product.
    What are the precautions in storage and transportation of 4-Fluoro-2-Difluoromethoxynitrobenzene?
    4-Fluoro-2-difluoromethoxy nitrobenzene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
    Bear the brunt, and the storage place must be cool and dry. This compound is afraid of moisture and heat. If it is placed in a high temperature and humid place, it may cause its chemical properties to mutate and even cause danger. Therefore, it is advisable to choose a well-ventilated warehouse with constant temperature, and the temperature of the warehouse should be controlled within a specific range to prevent its deterioration.
    Furthermore, it is toxic and corrosive to a certain extent. When storing, it must be stored in a suitable container, which must be resistant to corrosion and tightly sealed to prevent leakage. During transportation, it is also necessary to ensure that the container is stable and will not be damaged due to bumps and collisions.
    In addition, this compound may react violently with other substances. When storing and transporting, do not mix with reducing substances, acids, alkalis, etc., to avoid chemical reactions, resulting in serious consequences such as fire and explosion.
    When handling, the operator should be in front of suitable protective equipment, such as protective clothing, gloves, goggles, etc., to prevent contact with this object and injury to the body. In case of accidental contact, rinse with plenty of water as soon as possible and seek medical attention in time.
    When storing and transporting 4-fluoro-2-difluoromethoxynitrobenzene, it is necessary to adhere to relevant safety procedures and exercise caution to ensure the safety of personnel and the environment.
    What is the market outlook for 4-Fluoro-2-Difluoromethoxynitrobenzene?
    4-Fluoro-2-difluoromethoxy-nitrobenzene is an important raw material in organic synthesis. In the current market, the perspective of its prospects is related to the number of ends.
    From the perspective of demand, this compound is widely used in the fields of medicine and pesticides. In pharmaceutical research and development, due to its special chemical structure, it can be used as a key intermediate to make special new drugs. In recent years, the pharmaceutical industry has developed rapidly, and the demand for new drugs is increasing, which drives the demand for 4-fluoro-2-difluoromethoxy-nitrobenzene. In the field of pesticides, in order to respond to the development trend of green and efficient pesticides, the research and development of innovative pesticides containing this ingredient is also a hotspot, and the market demand expands accordingly.
    On the supply side, its production involves specific technologies and processes. Some production processes may pose challenges to environmental protection and safety. However, with the advance of science and technology, new production processes are gradually emerging, which is expected to increase production capacity and reduce production costs. At present, the global chemical industry landscape is changeable, and some traditional production areas may have adjusted production due to policy and cost factors. If emerging chemical regions can master technology, they can fill the shortage of supply.
    The state of market competition also affects its prospects. Internationally, chemical giants account for the majority of the market with their technological and scale advantages. However, domestic chemical companies have caught up in recent years, with technological upgrades and capacity expansion, intensifying market competition. In order to compete for share, various enterprises are focusing on quality improvement, price optimization, and service improvement.
    To sum up, although the market prospect of 4-fluoro-2-difluoromethoxynitrobenzene has broad space due to demand growth, it also faces the challenge of supply adjustment and intensified competition. If enterprises want to gain a place in the market, they need to emphasize technological innovation and quality control to adapt to market changes.