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4-Fluoro-2,6-Dimethylbromobenzene

4-Fluoro-2,6-Dimethylbromobenzene

Hongda Chemical

Specifications

HS Code

228921

Chemical Formula C8H8BrF
Molar Mass 203.05 g/mol
Appearance Colorless to light yellow liquid
Boiling Point ~198 - 200 °C
Density Approximately 1.47 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ether
Flash Point Caution: Flammable, flash point around 77 °C
Vapor Pressure Low vapor pressure at room temperature

As an accredited 4-Fluoro-2,6-Dimethylbromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - fluoro - 2,6 - dimethylbromobenzene packaged in a sealed glass bottle.
Storage 4 - fluoro - 2,6 - dimethylbromobenzene should be stored in a cool, dry, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly - sealed container to prevent vapor release. Store it separately from oxidizing agents and reactive substances. Ensure proper labeling for easy identification and to comply with safety regulations.
Shipping 4 - fluoro - 2,6 - dimethylbromobenzene is shipped in sealed, corrosion - resistant containers. They are carefully packaged to prevent breakage and ensure safe transport, following strict chemical shipping regulations.
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4-Fluoro-2,6-Dimethylbromobenzene 4-Fluoro-2,6-Dimethylbromobenzene
General Information
Historical Development
4 - Fluoro - 2,6 - Dimethylbromobenzene, the special product of chemistry. Its beginning is also derived from the research of various sages. At that time, the field of chemistry was exploring Fang Xing, and everyone was working hard to get new things to expand the world.
At the beginning, the preparation method was simple but not refined, and the yield was quite small, but Zhu Xian was not discouraged. After years of study, the technique became more and more mature. In the past, the preparation of raw materials was rare, the process was complicated, and every failure was caused.
After that, there were wise people who thought about changes and sought new ways to improve the path. The raw materials were selected by clever methods, and the steps were optimized, so that the yield gradually increased and the quality was also good. Therefore, 4 - Fluoro - 2,6 - Dimethylbromobenzene in various fields of chemical industry, gradually showing its ability, and its use is becoming more and more extensive, helping many industries, and contributing to the progress of chemistry. The process of its development is actually the coagulation of the efforts of all wise men and the fruit of wisdom.
Product Overview
4-Fluoro-2,6-dimethyl bromobenzene is an organic compound. It may be a colorless liquid with a special odor. In this compound, fluorine, bromine and methyl groups are linked, giving it unique chemical properties.
Its preparation method, or through a multi-step reaction. First, with appropriate raw materials, methyl is introduced through substitution reaction, and then fluorine atoms are introduced, and finally the product is obtained by bromination. The reaction process requires precise temperature control, time control, and strict environmental requirements for the reaction to ensure the purity and yield of the product.
4-fluoro-2,6-dimethyl bromobenzene is widely used in the field of organic synthesis. It can be used as an intermediate to prepare various drugs, pesticides and functional materials. Its special structure makes it exhibit unique activity in chemical reactions, providing the possibility for the synthesis of novel compounds, and is of great value in chemical research and industrial production.
Physical & Chemical Properties
4-Fluoro-2,6-dimethyl bromobenzene is also an organic compound. Its physical and chemical properties are related to scientific research and application, and cannot be ignored.
Looking at its physical properties, at room temperature, this substance may be in a liquid state, with a specific color and taste, but the color and taste depend on the specific purity. Its density is different from that of water, and it has good solubility in organic solvents. This is because its molecular structure contains aromatic rings and halogenated groups.
On its chemical properties, bromine groups are active and prone to substitution reactions, such as nucleophilic substitution, which can introduce various functional groups and expand their derivation paths. Fluorine atoms have strong electronegativity, which affects the distribution of molecular electron clouds, resulting in their unique chemical activity. Methyl increases molecular fat solubility and affects reaction check point activity. In summary, it lays the foundation for applications in organic synthesis, drug development and other fields.
Technical Specifications & Labeling
4-Fluoro-2,6-dimethyl bromobenzene is an important raw material for organic synthesis. Its process specifications and identification (product parameters) are fundamental to production and application.
In terms of process specifications, the purity of raw materials must reach extremely high standards, and the impurity content must be minimal to ensure accurate reaction. The synthesis steps are rigorous and orderly, and the reaction temperature, duration, and catalyst dosage are all accurately specified. If the reaction temperature should be controlled in a specific range, if it is too high, side reactions will occur frequently, and if it is too low, the reaction will be slow and difficult.
In terms of identification, the product must be clearly marked with the basic parameters such as chemical name, molecular formula, and molecular weight. On the packaging, warning labels are also indispensable to clarify its chemical properties, such as whether it is flammable, toxic, etc., so that the user can be aware of it, and proceed with caution when operating to ensure production safety and product quality. In this way, only in the field of chemical industry can we make good use of this product and maximize its effectiveness.
Preparation Method
There is a way to make 4 - Fluoro - 2,6 - Dimethylbromobenzene this product. First, take an appropriate amount of 2,6 - dimethylphenol as the raw material, and use hydrofluoric acid. After a delicate reaction process, 2,6 - dimethylfluorobenzene can be obtained.
Then, 2,6 - dimethylfluorobenzene is placed in a specific reaction environment, and a brominating agent is used to respond to it to control its temperature and time. After this reaction step, 4 - Fluoro - 2,6 - Dimethylbromobenzene is obtained.
The mechanism of its preparation is due to the reaction of hydrofluoric acid and 2,6-dimethylphenol, which can make fluorine atoms substitution phenolic hydroxyl groups cleverly to form 2,6-dimethylfluorobenzene. After the reaction of brominating agent and 2,6-dimethylfluorobenzene, bromine atoms are selected and replaced to eventually become the target. This preparation method is organized in the selection of raw materials, the control of reaction process, the advancement of reaction steps and the generation mechanism, and can obtain a relatively pure 4-Fluoro-2,6-Dimethylbromobenzene.
Chemical Reactions & Modifications
Since modern times, the art of chemistry has advanced day by day, and the insight into the change of matter has become clearer and clearer. On 4 - Fluoro - 2,6 - Dimethylbromobenzene today, the chemical reaction and modification of this substance are the most important research of our generation.
4 - Fluoro - 2,6 - Dimethylbromobenzene has a unique structure, which makes it behave differently in various reactions. Looking at the reaction, new groups can be introduced in the way of nucleophilic substitution, but their steric resistance and electronic effects are often constraints on the reaction. To change its properties or adjust the conditions of the reaction, control the properties of temperature, pressure and solvent, so that the reaction goes in the desired direction. Or change the surrounding groups, with the change of electron cloud, to promote the ease of reaction.
The purpose of modification, or to seek the purity of the product, or to increase its activity, so that it can be used in chemical and pharmaceutical fields. We should study its chemical reaction mechanism in depth, and use the method of modification to make it easier for academia and industry.
Synonyms & Product Names
Today there is a thing called 4 - Fluoro - 2,6 - Dimethylbromobenzene. Although its name is complex, it is very important in the field of my chemical research.
This thing also has its own name. For the sake of research, it is often called by another name. Its characteristics are unique, and it is widely used in the chemical industry. It can be used as a raw material to participate in various reactions and produce various products; or as a medium to help reactions run smoothly and change the properties of substances.
Our chemical researchers, examine its properties carefully, explore the rules of its changes, and hope to make good use of it to create more beneficial things for the world to use. On the experimental platform, observe its changes in detail, remember its numbers, analyze its principles, and expect to be able to understand its similar names and functions, which will lead to a higher level of chemistry.
Safety & Operational Standards
4 - Fluoro - 2,6 - Dimethylbromobenzene Safety and Operating Practices

The 4 - Fluoro - 2,6 - Dimethylbromobenzene is a common compound in chemical research. During its experimental operation, safety and standardization are the top priority.
#1. Storage Rules
This compound should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics to prevent accidental explosion. Because of its certain chemical activity, it cannot be mixed with oxidants, acids and other substances to prevent violent chemical reactions. The storage container must be tightly sealed to prevent it from evaporating and escaping, polluting the environment, and should be clearly marked, indicating key information such as name, nature and hazard.
#2. Qualified operation
The operator must be professionally trained and familiar with its nature and operation process. When operating, in front of appropriate protective equipment, such as protective glasses, it can effectively block the liquid that may splash and protect the eyes; wear chemical resistant gloves to avoid contact with the skin; wear protective clothing to protect the body in all aspects. It is best to operate in the fume hood, which can drain the volatile gas in time and reduce the concentration of harmful substances in the air.
When taking this compound, the action should be gentle and precise. Take it according to the amount required by the experiment. Do not take too much waste, and also prevent danger caused by excess. If it is accidentally spilled, do not panic, and start emergency treatment procedures immediately. If a small amount is spilled, it can be absorbed by inert materials such as sand and vermiculite, and properly disposed of after collection; if a large amount is spilled, it is necessary to evacuate people, seal the scene, and clean up by professionals.
#3. Emergency measures
If the skin comes into contact with this compound, you should immediately remove the contaminated clothing, rinse with a large amount of flowing water for at least 15 minutes, and then seek medical treatment. If it splashes into the eyes, quickly rinse with a large amount of water, lift the eyelids, ensure thorough rinsing, and then seek medical attention as soon as possible. If inhaling its volatile gas, it should be quickly moved to a fresh air place to keep the respiratory tract unobstructed. If breathing difficulties, give oxygen, and immediately perform artificial respiration if breathing stops, and quickly send to the hospital.
In summary, in the research and use of 4-Fluoro-2,6-Dimethylbromobenzene, strict adherence to safety and operating standards can ensure the smooth operation of the experiment, ensure the safety of personnel, and maintain the cleanliness of the environment.
Application Area
4-Fluoro-2,6-dimethyl bromobenzene is also an organic compound. Its application field is quite extensive. In the field of medicinal chemistry, it can be used as an intermediate to help create new drugs or have a healing effect on specific diseases. In materials science, it can be used as a raw material for synthesizing materials with special properties, so that the materials have unique physical or chemical properties. In the field of fine chemistry, it is used to prepare high-value-added fine chemicals and increase their commercial value. Its application in various fields, such as the bright stars, has added a lot of help to chemical research and industrial development, allowing researchers to continue to explore, to expand its wider application world, and to contribute to human well-being.
Research & Development
In recent years, I have focused on the research of 4 - Fluoro - 2,6 - Dimethylbromobenzene. This compound has a unique structure and great potential in the field of organic synthesis.
Initially, the synthesis process was full of thorns. The raw material ratio was slightly poor, and the reaction was not as expected. However, I was not discouraged. After repeated experiments and fine-tuning the parameters, I finally got the ideal method. With a specific catalyst, the temperature was controlled at a suitable range, the reaction was smooth, and the yield gradually increased.
After obtaining a good synthesis method, its application was explored. In the preparation of new materials, 4 - Fluoro - 2,6 - Dimethylbromobenzene exhibited unique properties, which could optimize the stability and conductivity of the material. I also communicated with my colleagues to discuss the expansion strategy. We hope to develop more novel and practical products based on it, promote the progress and development of this field, and contribute to chemical research.
Toxicity Research
4 - Fluoro - 2,6 - Dimethylbromobenzene is a chemical substance. I am a chemical researcher and have been studying its toxicity for many years.
The toxicity study of this compound is extremely important. In its chemical structure, the combination of fluorine, bromine and methyl may affect its toxicity performance. Experiments have shown that if organisms touch this, there may be different reactions. At the cellular level, it may interfere with the normal physiology of cells, affect metabolism and proliferation. In animal experiments, inhalation or contact with the medium containing this substance may cause respiratory and nervous system discomfort.
However, the toxicity research still needs to be deepened. Understanding the exact toxic mechanism, understanding the transformation in the environment and the long-term impact on the ecology are the focus of our follow-up research. Only by understanding its toxicity can we properly prevent and reduce its harm to life and the environment during production and use.
Future Prospects
Fu 4 - Fluoro - 2,6 - Dimethylbromobenzene, the chemical substance I have studied is also. Looking at its future, the prospect is clear. This substance may emerge in the field of medicinal chemistry, as a medicine for special effects, to eliminate human diseases, and to achieve great effects. In the field of material science, it is also expected to open up new frontiers, add its characteristics to the system of new materials, and expand its uses.
We should study diligently, use its physicochemical properties, and explore the rules of its reaction. Hope to make it in high quantities and high quality with precise methods. With time, we will be able to make this substance do our best to shine in various fields and benefit the world. This is our future ambition.
Where to Buy 4-Fluoro-2,6-Dimethylbromobenzene in China?
As a trusted 4-Fluoro-2,6-Dimethylbromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Fluoro-2,6-Dimethylbromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 4-fluoro-2,6-dimethyl bromobenzene?
4-Alkane-2,6-dimethylanisole is a kind of organic compound. Its chemical properties are as follows:
- ** Stability **: Under normal conditions, 4-alkane-2,6-dimethylanisole has a certain stability. In the molecular structure of this compound, the benzene ring is quite stable due to the conjugation system; and the existence of alkanes and methoxy groups does not give it a highly reactive activity check point. Therefore, under normal environmental conditions such as temperature and humidity, it can exist relatively stably, and it is not easy to decompose or other violent chemical reactions on its own.
- ** Nucleophilic Substitution Reaction **: The methoxy group (-OCH 🥰) is a more active group in this compound. The oxygen atom in the methoxy group is rich in lone pair electrons and exhibits a certain nucleophilicity. When encountering suitable electrophilic reagents, nucleophilic substitution reactions can occur. For example, if a halogenated hydrocarbon reacts with it, the oxygen atom of the methoxy group will attack the carbon atom of the halogenated hydrocarbon, and the halogen atom will leave as a leaving group to form a new compound. This reaction is often used in the field of organic synthesis to construct more complex molecular structures.
- ** Oxidation reaction **: Although the benzene ring is relatively stable, 4-alkane-2,6-dimethylanisole can still be oxidized under the action of specific strong oxidants. For example, in the presence of strong oxidants such as potassium permanganate and the reaction conditions are suitable, the alkyl group on the benzene ring may be oxidized to a carboxyl group. However, to achieve the oxidation of the benzene ring itself, more severe reaction conditions are required, because the conjugate system imparts high stability to the benzene ring.
- ** Substitution reaction **: The electron cloud density distribution on the benzene ring changes due to the influence of methoxy groups. Methoxy groups are ortho and para-sites, which will increase the density of electron clouds in the ortho and para-sites of the benzene ring, making it more susceptible to attack by electrophilic reagents and electrophilic substitution reactions. For example, when reacting with halogen elements catalyzed by iron halide, halogen atoms tend to replace the hydrogen atoms in the ortho and para-sites of the benzene ring to generate corresponding halogenated products.
What are the common methods for synthesizing 4-fluoro-2,6-dimethyl bromobenzene?
The common synthesis methods of 4-hydroxy-2,6-dimethylphenol are as follows:
1. ** Synthesis method using m-cresol as raw material **:
-m-cresol is first reacted with methylating reagents such as dimethyl sulfate under alkaline conditions, and sodium hydroxide can be selected for the base. This reaction can be carried out in a suitable organic solvent such as toluene, and the reaction temperature is controlled within a certain range, usually 50-80 ° C. In an alkaline environment, the methyl group of dimethyl sulfate will replace the hydrogen atom at the hydroxyl ortho-position of m-cresol phenol to generate 4-methoxy-2,6-dimethylbenzene. After that, through hydrolysis reaction, the methoxy group is hydrolyzed under acidic conditions to regenerate the phenolic hydroxyl group to obtain the target product 4-hydroxy-2,6-dimethylphenol.
- The reaction step is simple, and the raw material inter-cresol is relatively easy to obtain. However, the dimethyl sulfate used in the reaction is more toxic, and the operation needs to be cautious, and the control of the reaction conditions has a great impact on the purity and yield of the product.
2. ** Synthesis of hydroquinone as raw material **:
- Hydroquinone reacts with methylating reagents such as iodomethane or dimethyl sulfate in the presence of a suitable catalyst. The catalyst can be selected from potassium carbonate, etc., and the reaction is carried out in an organic solvent such as N, N-dimethylformamide (DMF). By controlling the reaction conditions, methyl preferentially replaces the hydrogen atom of one of the phenolic hydroxyl orthopositions of hydroquinone to generate 4-hydroxy-2-methylanisole. Then the methylation reaction is carried out again, and the appropriate methylation reagent and reaction conditions are selected to introduce the other orthoposition into the methyl group to obtain 4-methoxy-2,6-dimethylbenzene, and finally the methoxy group is hydrolyzed to obtain the target product.
- Using hydroquinone as the raw material, the position of the substituent can be better controlled. However, there are relatively many reaction steps, and precise control of the reaction conditions is required to avoid side reactions such as excessive methylation.
3. ** Synthesis method using o-cresol as raw material **:
-o-cresol is first acylated with an acylating agent such as acetyl chloride under the catalysis of a catalyst such as aluminum trichloride. The reaction is carried out at a low temperature, such as 0-10 ° C, where an acyl group is introduced at the phenolic hydroxyl para-position of o-cresol. Subsequently, the acylation product is reduced, and the acyl group can be reduced to methyl using reducing agents such as zinc amalgam and concentrated hydrochloric acid, thereby obtaining 4-hydroxy-2,6-dimethylphenol. The cost of the raw material o-cresol in this method is low, but the acylation reaction requires a high catalyst, and the zinc amalgam and other reagents used in the reduction step have certain pollution to the environment, and the post-treatment is more complicated.
What are the main applications of 4-fluoro-2,6-dimethyl bromobenzene?
4-Heptyl-2,6-dimethylbenzaldehyde is widely used. In the field of fragrances, it can add luster to the blending of floral, fruity and other fragrances with its unique aroma, endowing perfumes, air fresheners, detergents and other products with fascinating fragrance and enhancing their olfactory experience. In the field of medicine and chemical industry, it is an important intermediate, assisting in the synthesis of drugs with specific physiological activities, which is of great significance for the development of drugs for the treatment of specific diseases. In the field of organic synthesis, as a key starting material or reaction intermediate, it participates in the construction of many complex organic compounds and expands the boundaries of organic synthesis.
Viewing this 4-Heptyl-2,6-dimethylbenzaldehyde, its application in fragrances can create a unique atmosphere. Just as "Tiangong Kaiwu" said: "Water and fire are both good and soil are harmonious." The preparation of fragrances requires each ingredient to complement each other, and 4-heptyl-2,6-dimethylbenzaldehyde is in it, like a delicate music note, integrated into the aroma movement, playing a beautiful melody. In the pharmaceutical industry, it is like the ingenious use of materials by craftsmen in "Tiangong Kaiwu", using its characteristics to open a new path of drug synthesis. In organic synthesis, like the cornerstone in the hands of skilled craftsmen, it builds a magnificent building of complex organic compounds, leading organic synthesis to a new height, injecting vitality and possibility into the development of many fields.
What should I pay attention to when storing and transporting 4-fluoro-2,6-dimethyl bromobenzene?
4-Dimethylphenyl ether is also an organic compound. When storing and transporting it, pay attention to many matters.
First word storage. This substance should be placed in a cool and ventilated warehouse. Because of the cool and ventilated place, it can reduce the danger caused by excessive temperature or lack of air circulation. If it is in a high temperature environment, there may be a risk of chemical reaction, combustion or even explosion. And it should be kept away from fire and heat sources, both of which are possible sources of fire. If you are not careful, contact with this compound will easily cause disasters. At the same time, it needs to be stored separately from oxidants, acids, etc., because of its active chemical properties, it can mix with other substances, or react violently.
Times and transportation. When transporting, it is necessary to ensure that the container does not leak, collapse, fall, or damage. If this compound leaks, or pollutes the environment, it endangers the safety of humans and animals. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment for emergencies. During transportation, it should be protected from exposure to the sun, rain, and high temperature. Exposure to the sun and high temperature or cause changes in their properties, and rain may cause them to react with water, resulting in adverse consequences. Road transportation should follow the prescribed route and do not stop in residential areas and densely populated areas. In order to avoid accidents during transportation and cause serious harm to many people. In this way, the safety of 4-dimethylphenyl ether storage and transportation can be guaranteed.
What is the approximate market price of 4-fluoro-2,6-dimethyl bromobenzene?
The market price of Guanfu 4-hydroxyl-2,6-dimethylbenzoquinone is difficult to determine. The price of the cap often varies for many reasons.
It is related to the source of the material. If the raw materials are widely produced and easy to obtain, and it is not difficult to obtain, the price will be flat. On the contrary, if the raw materials are scarce, difficult to obtain, and difficult to obtain, the price will rise.
The method of preparation is also heavy. A good method can save labor and materials, improve its yield, and reduce the cost, and the price will also drop. If the method of making is clumsy, time-consuming and laborious, and the cost is high, the price will be expensive.
The supply and demand of the city is the cardinal of the price. If there are many people who want it, they will use it widely, but the supply is insufficient, and the price will rise. If there is a shortage of demand, the stock will be in surplus, and the price will fall.
Furthermore, changes in the current situation and decrees and regulations can affect its price. At this moment, there is no definite price. However, according to common sense, its price often fluctuates between hundreds and thousands of yuan per kilogram. Or it varies due to the superiority of quality and quantity. To know the exact price, you must observe the real-time market conditions of the market and consult the merchants and operators to obtain the exact number.