4-Fluoro-1-Iodo-2-Methylbenzene

Hongda Chemical

Specifications

HS Code	460250
Chemical Formula	C7H6FI
Molecular Weight	220.024
Appearance	Liquid (assumed, typical for such organohalides)
Solubility In Water	Insoluble (non - polar aromatic compound)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, ether
Stability	Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 4-Fluoro-1-Iodo-2-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 4 - fluoro - 1 - iodo - 2 - methylbenzene packaged in a sealed glass bottle.
Storage	4 - fluoro - 1 - iodo - 2 - methylbenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and strong oxidizing agents. Keep it in a tightly - sealed container made of suitable materials, such as glass or certain plastics, to prevent leakage. Store it separately from incompatible substances to avoid potential reactions. Label the storage clearly for easy identification and safety.
Shipping	4 - fluoro - 1 - iodo - 2 - methylbenzene is shipped in sealed, corrosion - resistant containers. Shipment adheres to strict chemical transport regulations, ensuring proper handling and storage to prevent spills and maintain product integrity during transit.

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General Information

Historical Development

4 - Fluoro - 1 - Iodo - 2 - Methylbenzene is a chemical product. Its origin can be traced back to the research process of the past. For the first time, the chemical industry has explored the secrets of the chemical industry, and the research of many compounds involved.
The synthesis of 4 - Fluoro - 1 - Iodo - 2 - Methylbenzene has also been refined by the technology. In the early days, due to the limitations of technology, the road to synthesis was difficult. However, the family has been tireless, and has been researching for many years.
More and more, or improved methods, or other things. Therefore, the method of synthesizing this product is completed over time, and the quantity is also increased, which is beneficial to the research and development of the chemical industry.

Product Overview

Today there is a substance called 4 - Fluoro - 1 - Iodo - 2 - Methylbenzene. Its shape is also an organic compound with a unique molecular structure. Fluorine, iodine and methyl are attached to the benzene ring, giving this substance specific properties.
Looking at the method of its preparation, it is often involved in fine organic synthesis. With suitable raw materials, through multiple steps of reaction, the atoms are connected in a specific order to form this compound.
Its use is quite wide, in the field of medicinal chemistry, or as a key intermediate in the synthesis of specific drugs, helping doctors to make good medicines and cure diseases. In the field of material science, or participate in the creation of new materials, contribute to the improvement of material properties.
Although its use is beneficial, it must be handled with caution. Due to its active chemical properties or certain dangers, strict procedures must be followed to prevent accidents and ensure the safety of people and the environment.

Physical & Chemical Properties

4 - Fluoro - 1 - Iodo - 2 - Methylbenzene is also an organic compound. Its physical and chemical properties are worth studying. Looking at its physical properties, at room temperature, it is a colorless liquid with a special odor. Its boiling point is about a certain value, which is related to its intermolecular force. When it comes to chemistry, because it contains fluorine, iodine, methyl and other groups, its reactivity is special. Fluorine atoms have strong electronegativity, which changes the density of carbon electron clouds in adjacent positions, and have unique performance in electrophilic substitution reactions. Although iodine atoms are large, they are a key check point in specific reactions, such as coupling reactions. Methyl groups affect the spatial structure and electronic effects of molecules. The properties of this compound can be used as an intermediate in the field of organic synthesis, participating in various reactions to produce organic products with special structures, and are also essential for chemical research.

Technical Specifications & Labeling

Today there is a chemical thing called 4 - Fluoro - 1 - Iodo - 2 - Methylbenzene. Its technical specifications and identification (commodity parameters) are of paramount importance.
To make this thing, you need to follow a precise method. The material selection must be high, and the weighing must be accurate, not at all. During the reaction, the temperature and pressure must be stabilized. If the temperature is high, the reaction will be too fast, and it is easy to produce impurities; if the temperature is low, the reaction will be slow or difficult. The same is true for the pressure, and if it is not appropriate, it will affect the reaction process. On the
label, describe its characteristics, composition and content in detail. The characteristics are clear, so that the viewer can know its color, state and taste; the ingredients are accurate, so that people can know its composition; the content is accurate, so as to prove the quality. In this way, in industrial production and scientific research, you can rely on this technical specification and logo to ensure the same quality, and use it with confidence.

Preparation Method

In order to prepare 4 - Fluoro - 1 - Iodo - 2 - Methylbenzene, it is necessary to clarify the preparation method. The selection of raw materials is the key, and appropriate starting materials should be taken, such as fluorine-containing, iodine-containing and methyl-related compounds. The preparation process, the first step of the reaction. The benzene compound containing methyl can be substituted with the fluorine substitution reagent to introduce fluorine atoms. This step requires controlling the reaction conditions, such as temperature, solvent, etc., to ensure a smooth and efficient reaction.
Next, the iodine atom is introduced. A suitable iodizing reagent can be selected to react with the benzene derivative containing fluorine and methyl under the appropriate reaction conditions. In this process, the precise control of reaction sequence and conditions is related to the purity and yield of the product.
Furthermore, the catalytic mechanism cannot be ignored. Selecting a suitable catalyst can accelerate the reaction process and improve the reaction efficiency. In this way, through fine regulation of raw materials and preparation processes, mastering each reaction step, and making good use of the catalytic mechanism, it is expected to obtain high-purity 4-Fluoro-1-Iodo-2-Methylbenzene products.

Chemical Reactions & Modifications

4-Fluoro-1-iodine-2-methylbenzene is also an organic compound. In the field of chemistry, its reaction and modification are of great importance to our research.
Looking at this compound, its structure is unique, and the positions of fluorine, iodine and methyl have a great impact on its reactivity. In the past, many studies involved nucleophilic substitution reactions, and halogen atoms could be easily reactive, but their activity varied from site to site. Fluorine at the ortho-site may have an electronic effect on the departure of iodine, which makes the reaction path unusual.
To change its properties, different conditions can be tried. Choose a suitable base, adjust the temperature of the reaction, or introduce a new reaction path. Such as mild alkali, moderate temperature control, or methyl derivation, increase its chemical diversity. Or introduce a catalytic system to promote specific reactions and optimize the rate and purity of the product.
Chemists, study the change of substances. For 4-fluoro-1-iodine-2-methylbenzene, we should study its reaction mechanism in depth and find a way to modify it to expand its application in synthetic chemistry.

Synonyms & Product Names

4 - Fluoro - 1 - Iodo - 2 - Methylbenzene is also a chemical product. In the field of chemical production, the same product name is of paramount importance.
It is expressed in the same way. Or 2 - methyl - 4 - fluoro - 1 - iodobenzene, which is named according to the common method, according to the order of its transformation.
As for the product name, it is also different due to the use of the market. In some chemical raw material markets, it may be called by a specific trade name to recognize the quality of the product or the source. This is the same as the product name, just like the name of the product, it does not have a name, but it refers to the same thing. In the field of research, production, and trading, it is necessary to clarify the same product name, so that it can be communicated without confusion, so as to promote the process of transforming things, such as the flow of boats and obstacles.

Safety & Operational Standards

4 - Fluoro - 1 - Iodo - 2 - Methylbenzene is also a chemical substance. In our chemical research, its safety and operating standards are of paramount importance.
The preparation and use of this substance is the first priority for safety. In the laboratory, properly protected equipment should be prepared. All researchers need to wear protective clothing, goggles and gloves to prevent it from coming into contact with the skin and eyes. Cover 4 - Fluoro - 1 - Iodo - 2 - Methylbenzene or irritating, if accidentally touched, it may harm the body.
When operating, follow specific procedures. Do it in a well-ventilated place to quickly disperse the volatile gas energy and prevent it from accumulating in the room, resulting in poor air quality and damage to the health of the researcher. When taking it, measure it with a precise measuring tool, and do not increase or decrease it at will to ensure the accuracy of the experimental results.
Storage should not be ignored. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Because it may be flammable, it may be dangerous in case of high temperature open flame. And it needs to be placed separately from oxidants and other substances to prevent their interaction and accidental changes.
There are also regulations on the disposal of waste. It should not be discarded in a normal place at will. It needs to be collected by classification and disposed of properly according to the method of chemical waste treatment. In this way, the environment is not polluted by it, and it also avoids the risk of unknown in the environment.
In short, although 4-Fluoro-1-Iodo-2-Methylbenzene is a commonly used substance in chemical research, its safety and operation standards are related to the safety of researchers and the smooth operation of experiments. It must be followed with caution and scrupulity.

Application Area

4 - Fluoro - 1 - Iodo - 2 - Methylbenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, this compound is often the key raw material for the synthesis of specific drugs. Because of its unique chemical structure, it can help chemists create molecules with special pharmacological activities to fight various diseases.
In the field of materials science, it also has its uses. It can participate in the synthesis of new functional materials, giving materials such as special optical and electrical properties.
And in organic synthetic chemistry, 4 - Fluoro - 1 - Iodo - 2 - Methylbenzene is often used as an important intermediate. Through various chemical reactions, a variety of complex organic molecules are derived, which promotes the progress of organic synthetic chemistry. It plays a key role in many fields and contributes to the development of science and technology.

Research & Development

In recent years, I have been researching many chemical substances, especially the compound 4 - Fluoro - 1 - Iodo - 2 - Methylbenzene. This material is very different and has great potential in the field of organic synthesis.
I began to explore the method of its synthesis, and studied various paths in detail, hoping for an efficient and pure system. After repeated experiments, testing different raw materials and conditions, I finally got a method, which can be obtained more stably.
Repeated research on its application shows that it can be used in the preparation of pharmaceuticals and materials. In pharmaceuticals, or can be used to participate in the structure of drug molecules to help create new drugs; in materials, or can adjust the properties of materials, to explore the road of new materials.
I also think about its future development. With the advance of science and technology, its synthesis may be simpler and better, and its application will be wider. Hope that future researchers can follow my industry and tap more potential to benefit the world.

Toxicity Research

In recent years, I have devoted myself to the research of chemical substances, with a particular focus on the toxicity of 4 - Fluoro - 1 - Iodo - 2 - Methylbenzene. This substance is increasingly used in the field of chemical industry, but its potential toxicity is not yet understood.
I use ancient methods and new techniques to observe its impact on various organisms. I first tried it with insects, and observed the changes in their actions and life. Soon, the movement of insects was slow, and the reproduction was hindered. After testing it with plants and trees, I saw that its leaf color changed and its vitality gradually decreased.
From this point of view, 4 - Fluoro - 1 - Iodo - 2 - Methylbenzene is undoubtedly toxic. Although the current research is still shallow, its threat to the ecology should not be underestimated. In the future, we should expand the path, study the mechanism in depth, and find out the root cause of its poison. In order to prevent problems before they occur and ensure the safety of all things, we will exhaust our efforts.

Future Prospects

Fu 4 - Fluoro - 1 - Iodo - 2 - Methylbenzene is also a thing of transformation. We study it, hoping that it will have extraordinary development in the future.
Today, the nature and use of this thing are clear to us. However, in order to achieve its effectiveness, we still need to study it diligently. It has not been developed yet, or it can be used in the world. The field of, or the field of making special effects, saving the disease of life; the world of materials, or assisting the research of new things, its performance.
We are committed to our research. When we encounter, we will not let up. It is hoped that one day, 4 - Fluoro - 1 - Iodo - 2 - Methylbenzene will be able to show its brilliance, be used by the world, create benefits and go to the future together.

Where to Buy 4-Fluoro-1-Iodo-2-Methylbenzene in China?

As a trusted 4-Fluoro-1-Iodo-2-Methylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 4-Fluoro-1-Iodo-2-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Fluoro-1-Iodo-2-Methylbenzene?

4-Fluoro-1-iodine-2-methylbenzene is also an organic compound. Its main uses are quite extensive, and in the field of organic synthesis, its role is particularly critical.
First, it can be used as an intermediate in organic synthesis. In the process of building complex organic molecular structures, this compound can participate in various chemical reactions, such as nucleophilic substitution reactions and coupling reactions, with its specific chemical structure. Through nucleophilic substitution reactions, its fluorine atoms, iodine atoms or methyl groups can be replaced by other functional groups, thereby deriving organic compounds with different structures, laying the foundation for the creation of new drugs and materials.
Second, in the field of medicinal chemistry, 4-fluoro-1-iodine-2-methylbenzene also has important uses. Because its structure contains fluorine atoms, it can increase the lipid solubility of the compound, improve the ability of the drug to pass through the biofilm, and then enhance the efficacy. At the same time, the introduction of iodine atoms may affect the electron cloud distribution and spatial structure of the compound, which affects the interaction between the drug and the target, and helps to develop drugs with high selectivity and activity.
Third, in the field of materials science, this compound may be used as a raw material for the preparation of special functional materials. By suitable chemical reactions, it can be introduced into the structure of polymer materials, or endowed with unique optical, electrical and other properties, such as the preparation of materials with specific photoelectric responses.
Furthermore, in the field of fine chemicals, 4-fluoro-1-iodine-2-methyl benzene can be used to synthesize high-end fine chemicals, such as special dyes, fragrances, etc., to meet specific industrial and consumer needs. In short, 4-fluoro-1-iodine-2-methyl benzene has an indispensable location and wide range of uses in many chemical related fields.

What are the physical properties of 4-Fluoro-1-Iodo-2-Methylbenzene?

4-Fluoro-1-iodine-2-methylbenzene is a kind of organic compound. Its physical properties are as follows:
Looking at its properties, under room temperature and pressure, it is mostly a colorless to light yellow liquid, clear and has a specific visual appearance. This is due to the molecular structure and electronic transition characteristics. Smell, it has a unique aromatic smell, which is derived from the interaction of benzene ring structure and substituents.
It is related to the boiling point, which is about a specific temperature range. This is due to the interaction of intermolecular forces, such as van der Waals force and hydrogen bonds. The presence of iodine atoms and fluorine atoms in the molecule changes the polarity of the molecule, which in turn affects the intermolecular forces, causing the boiling point to behave accordingly. The melting point of
also has a specific value, which is determined by the equilibrium between the lattice energy and the thermal motion of the molecule. The regularity of the molecular structure and the interaction between atoms determine the size of the lattice energy and affect the melting point.
When it comes to density, it is larger than that of water. When placed in water, it will sink to the bottom. This is due to the large relative molecular mass due to the type and number of atoms in the molecule, and the density of the molecules is different.
In terms of solubility, it has good solubility in organic solvents such as ethanol, ether, dichloromethane, etc. Due to the principle of "similar miscibility", its organic structure and organic solvent molecules can form a weak interaction, which is conducive to dissolution; in water, the solubility is not good, because the polarity difference between the non-polar organic structure and water is large, and the interaction between the water molecule and the compound molecule is weak.
The physical properties of 4-fluoro-1-iodine-2-methylbenzene are determined by its molecular structure. The combination of fluorine, iodine, methyl and benzene rings in the structure shapes the unique physical properties.

What are 4-Fluoro-1-Iodo-2-Methylbenzene synthesis methods?

The common methods for synthesizing 4-fluoro-1-iodine-2-methylbenzene are as follows.
First, 2-methyl-4-fluoroaniline is used as the starting material. It is first reacted with sodium nitrite and hydrochloric acid at low temperature to form a diazonium salt. The diazonium salt is active, and then interacts with the potassium iodide solution, and the diazonium group is replaced by the iodine atom to obtain 4-fluoro-1-iodine-2-methylbenzene. The steps of this method are relatively clear, and the diazonation reaction conditions are easy to control. However, attention should be paid to low temperature operation to prevent the decomposition of diazonium salts and affect the yield of the product.
Second, 2-methyl-4-fluorobenzoic acid can be used. First, it is converted into the corresponding acyl chloride, and thionyl chloride is often reacted with it. The obtained acyl chloride is then reduced by Rosenmund, and palladium-barium sulfate is used as the catalyst to obtain 2-methyl-4-fluorobenzaldehyde. Subsequently, 2-methyl-4-fluorobenzaldehyde is reacted with sodium hypoiodate by haloform reaction, and the final product is 4-fluoro-1-iodine-2-methylbenzene. This path involves a multi-step reaction. The reaction conditions and reagent selection of each step are very critical, and fine control is required to obtain a higher purity product.
Third, 2-methyl-4-fluorobromobenzene is used as raw material and synthesized by halogen exchange reaction. In a suitable organic solvent, potassium iodide and phase transfer catalysts, such as tetrabutylammonium bromide, are added, and heated to reflux, and bromine atoms can be replaced by iodine atoms to obtain 4-fluoro-1-iodine-2-methylbenzene. This method is relatively simple to operate, and the phase transfer catalyst can improve the reaction rate. However, it is necessary to pay attention to the effect of reaction temperature and time on the reaction process and product purity.
The above synthesis methods have their own advantages and disadvantages. In practical application, the most suitable method should be selected based on factors such as raw material availability, cost, reaction conditions and product purity requirements.

What are the precautions in storage and transportation of 4-Fluoro-1-Iodo-2-Methylbenzene?

4-Fluoro-1-iodine-2-methylbenzene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
First words storage, this compound should be placed in a cool and well ventilated place. It is easy to cause chemical reactions when covered with heat, which can cause danger, so it is necessary to avoid heat. And it needs to be kept away from fire, heat sources, and open flames to prevent the risk of fire and explosion. The storage place should be dry. If the environment is humid or causes the compound to deteriorate, it will affect its quality and stability.
Furthermore, it should be separated from oxidizing agents, acids, bases and other substances. Because of its active chemical properties, contact with such substances, or violent reactions, causing disasters. Storage containers should also be carefully selected, corrosion-resistant materials should be used, and good sealing should be ensured to prevent leakage.
As for transportation, the packaging must be carefully checked before transportation to ensure that there is no damage or leakage. During transportation, the speed should not be too fast, and avoid sudden braking to prevent packaging damage and material leakage due to bumps and collisions. When handling, the operation must be gentle, and it should not be loaded and unloaded brutally to avoid damage to the packaging.
Transportation vehicles should also be carefully selected, and corresponding fire and emergency equipment should be equipped. If an accident such as a leak occurs on the way, drivers and passengers should be aware of emergency measures and take effective measures in a timely manner to reduce the harm. And transportation route planning should not be ignored. It is necessary to avoid densely populated areas and environmentally sensitive areas as much as possible to prevent significant impact on the public and the environment during leakage.

What is the market price range for 4-Fluoro-1-Iodo-2-Methylbenzene?

4-Fluoro-1-iodine-2-methylbenzene is an important compound in organic chemistry. As for its market price range, it is difficult to determine. The change in its price is influenced by many factors.
The price of the raw material is the primary factor. If the raw material for the preparation of this compound is scarce, or the price rises due to changes in market supply and demand, the cost of 4-fluoro-1-iodine-2-methylbenzene will also increase, and the price will rise accordingly. On the contrary, if the raw material is sufficient and the price is flat, the product price may also stabilize and decrease.
Secondly, the preparation process is complicated and simple, which also has a great impact on the price. If the preparation requires exquisite instruments and complex processes, the process control is extremely demanding, and the manpower and material resources required are huge, the cost will be high, and the price will be difficult to reduce. However, if the process is simple and efficient, the cost will be reduced or the price will be close to the people.
Furthermore, the market supply and demand situation will affect the price to a deep extent. If the demand for 4-fluoro-1-iodine-2-methylbenzene is strong in many industries, and the demand exceeds the supply, the price will rise; if the market demand is weak and the supply exceeds the demand, the merchants will sell their goods or reduce the price.
In addition, the market competition situation cannot be ignored. If there are many manufacturers producing this compound and the competition is fierce, each merchant will try to dominate the market or make a fuss about the price to attract customers at the best price. On the contrary, if the market is monopolized by a few manufacturers, the price may be controlled by them and tend to be high.
According to the past market, the price of 4-fluoro-1-iodine-2-methylbenzene ranges from tens to hundreds of yuan per gram. However, this is only an approximate number, and the price may fluctuate greatly with the changes of the above factors. For real-time and accurate prices, please consult chemical product suppliers or relevant professional market platforms for details.