4-Jiang-1,3-difluorobenzylbenzene, its main use is mostly related to the creation of medicine and pesticides.
In the field of medicine, it can be used as a key intermediate to prepare various drugs with specific physiological activities. Because its molecular structure contains fluorine atoms, the introduction of fluorine atoms can often significantly improve the physical, chemical and biological properties of compounds. For example, it can enhance the binding force between the drug and the target, improve the lipophilicity of the drug, and promote its easier penetration of biological membranes, thereby enhancing the bioavailability and efficacy of the drug. By ingeniously modifying the structure of 4-Jiang-1,3-difluorobenzylbenzene, chemists can derive a series of compounds, which can be screened and evaluated for activity, or can obtain highly effective and low-toxicity drugs for specific diseases, such as anti-tumor, antiviral and antibacterial drugs.
In the field of pesticides, this compound also has important applications. It can be used as a starting material for the synthesis of new pesticides. Due to its structural characteristics, the prepared pesticides may have excellent insecticidal, bactericidal or herbicidal activities. Fluorinated pesticides often have the advantages of high efficiency, low residue, and good environmental compatibility, which meet the strict requirements of modern green agriculture for pesticides. By converting 4-Jiang-1,3-difluorobenzylbenzene into various pesticide active ingredients, it can effectively prevent and control crop diseases and pests, ensure crop yield and quality, and reduce the negative impact on the environment, which contributes to the sustainable development of agriculture.
In summary, 4-Jiang-1,3-difluorobenzylbenzene has shown high application value in both the fields of medicine and pesticides, and is an important intermediate with great potential in the field of chemical synthesis.

4-Hydroxy-1,3-difluorobenzene is a special organic compound. Its physical properties are as follows:
Under normal temperature and pressure, it is mostly colorless to light yellow liquid with clear texture. This appearance characteristic is convenient for naked eye recognition and preliminary judgment.
When it comes to boiling point, its boiling point is about a certain range due to intermolecular forces, but the specific value will vary slightly due to environmental pressure. This boiling point characteristic is of great significance in practical operations such as separation, purification and storage. It is related to whether the substance can be treated at a suitable temperature to ensure its stability and will not decompose due to high temperature or solidify due to low temperature.
In terms of melting point, it also has a specific value, which is the critical temperature for the mutual transformation of solid and liquid states. Knowing the melting point, the temperature environment can be controlled accordingly during the preparation and storage of the substance to avoid accidental changes in the state of the substance.
The solubility of the substance is very important. The substance has a certain solubility in some organic solvents such as ethanol and ether. This property is conducive to its use as a reactant or intermediate in organic synthesis reactions. With the good solubility of organic solvents, the reaction is easier to carry out, and the reaction efficiency and product purity are improved.
The density is different from that of water, which needs to be taken into account when it comes to the operation of the mixed system, such as extraction, stratification and other processes. Effective separation operations can be achieved according to the density difference.
In addition, 4-hydroxy- 1,3-difluorobenzene has a certain volatility, although the volatility is affected by the ambient temperature, pressure and its own structure, but this property is essential for the ventilation conditions of storage and use places, to prevent it from accumulating in a limited space, causing safety hazards or affecting the experimental and production environment.

The chemical properties of 4-Fu-1,3-difluorobenzene are quite stable. Looking at the structure of this compound, the difluoro group resides at the 1,3 position of the benzene ring, and the fluorine atom has strong electronegativity, which can cause the electron cloud density distribution of the benzene ring to change abnormally.
The introduction of fluorine atoms, because the electronegativity of fluorine is greater than that of carbon, the C-F bond has strong polarity. However, it interacts with the benzene ring conjugated system, causing the electron cloud to redistribute. This structural feature makes 4-Fu-1,3-difluorobenzene stable to a certain extent.
In terms of reactivity, although the benzene ring is aromatic, it is more prone to electrophilic substitution. However, the electron-absorbing effect of fluorine atoms decreases the electron cloud density of the benzene ring, and the difficulty of attacking electrophilic reagents is slightly increased. Therefore, compared with ordinary benzene series, its electrophilic substitution reactivity is slightly reduced, which is also one of the evidence that its chemical properties tend to be stable.
Furthermore, the C-F bond energy is quite high, and more energy is required to break the bond. Therefore, under the general chemical reaction conditions, the C-F bond in 4-Fu-1,3-difluorobenzene is not easy to break, which further maintains the stability of its structure and makes its chemical properties relatively stable. In summary, the chemical properties of 4-Fu-1,3-difluorobenzene are relatively stable.

The synthesis of 4-alkyne-1,3-difluorobenzene has various approaches, which are described in detail below.
First, it can be started from halogenated aromatic hydrocarbons. First, take a suitable halogenated benzene, such as 1-halogenated-4-alkynylbenzene derivatives, whose halogen atom can be chlorine, bromine or iodine. In this halogenated benzene, a fluorine-containing group is introduced. Fluorinated reagents such as potassium fluoride, cesium fluoride, etc. are commonly used to carry out nucleophilic substitution reactions in the presence of suitable solvents and catalysts. If dimethyl sulfoxide is used as a solvent, an appropriate amount of phase transfer catalyst such as tetrabutylammonium bromide is used to assist, and the temperature is heated to a suitable temperature, so that the halogen atom is replaced by a fluorine atom, then the 4-alkynyl-1-fluorobenzene derivative is obtained. Then in a similar way, the second fluoro group is introduced at another suitable position, and the target product 4-alkynyl-1,3-difluorobenzene can be reached after reasonable regulation of the reaction conditions.
Second, the alkynyl group can be constructed by the alkynylation reaction. Prepare 1,3-difluorobenzene derivatives first, and introduce the alkynyl group by the palladium-cataly If the halogenated 1,3-difluorobenzene is used as the raw material, the palladium salt such as palladium acetate is used as the catalyst, the ligand such as triphenylphosphine is assisted, and the alkali such as potassium carbonate is present. Coupling reaction occurs with alkynyl tin reagent or alkynyl borate, etc., thereby generating 4-alkynyl-1,3-difluorobenzene.
Third, the strategy of constructing benzene rings is based on benzene rings. For example, through a multi-step reaction, the benzene ring is gradually constructed from a simple raw material and the desired substituent is First, fluorine-containing and alkynyl precursors are used as raw materials, and the benzene ring skeleton is constructed through cyclization reactions such as Diels-Alder reaction. Later, the functional group is converted and modified to form 4-alkynyl-1,3-difluoro-based structures at specific positions on the benzene ring.
This number method has its own advantages and disadvantages. In practical application, it needs to be weighed according to factors such as the availability of raw materials, the ease of control of reaction conditions and cost.

I have heard your inquiry about the price of 4-hydroxy- 1,3-difluorophenylbenzene in the market. However, the price of this chemical product often varies due to many factors, making it difficult to determine.
First, the quality and quantity of the product are the main factors. If its purity is high and the output is abundant, the price may be relatively stable; if the quality and quantity are small, the price will rise. Second, the trend of supply and demand is also influenced. If there are many people in need and few people in supply, the price will rise; on the contrary, if the supply exceeds the demand, the price will decrease. Third, the cost of production cannot be ignored. The price of raw materials, the simplicity of the work, and the amount of consumption all involve costs, which in turn affect their prices.
In the market, the price of such chemicals varies from tens to hundreds of dollars per gram. However, this is only an approximation, and the actual price should be determined by consulting the chemical market, supplier or industry in detail according to the real-time situation. I hope this answer will be helpful to you and solve your doubts.