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4-Fluoro-1,3-Benzenediol

4-Fluoro-1,3-Benzenediol

Hongda Chemical

Specifications

HS Code

449859

Chemical Formula C6H5FO2
Molar Mass 128.101 g/mol
Appearance White to off - white solid
Boiling Point 245 - 247 °C
Melting Point 130 - 133 °C
Solubility In Water Soluble
Density 1.423 g/cm³
Flash Point 115.7 °C
Pka1 9.24
Pka2 11.55

As an accredited 4-Fluoro-1,3-Benzenediol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - fluoro - 1,3 - benzenediol packaged in a sealed, chemical - resistant container.
Storage 4 - fluoro - 1,3 - benzenediol should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and air exposure, which could potentially lead to degradation. Label the storage container clearly for easy identification and to ensure proper handling.
Shipping 4 - fluoro - 1,3 - benzenediol is shipped in well - sealed containers, ensuring protection from moisture and contamination. Shipment follows strict chemical transportation regulations to safeguard safety during transit.
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4-Fluoro-1,3-Benzenediol 4-Fluoro-1,3-Benzenediol
General Information
Historical Development
4 - Fluoro - 1,3 - Benzenediol is a chemical substance with a considerable history. In the past, at the beginning of chemical research, the investigation of such compounds was still shallow. At that time, technology was not developed, analytical methods were scarce, and scholars could only initially understand its appearance.
However, the years pass, and technology advances day by day. With perseverance, chemists use increasingly sophisticated instruments to deeply analyze its structure. After countless experiments, the properties and reaction mechanism of 4 - Fluoro - 1,3 - Benzenediol have gradually become clear. This compound has emerged in the fields of medicine, materials and other fields, contributing to industrial progress. From ignorance to wide application, the historical development of 4 - Fluoro - 1,3 - Benzenediol is like a slowly unfolding picture, witnessing the vigorous progress of chemistry.
Product Overview
4 - Fluoro - 1,3 - Benzenediol is an important chemical product. This product has a unique chemical structure. Its molecule contains fluorine atoms connected to the benzene ring, and there are also two hydroxyl groups on the benzene ring. This structure gives it specific physical and chemical properties.
In terms of physical properties, it may have a specific melting point, boiling point and solubility. Chemically, hydroxyl groups can cause it to participate in many reactions, such as esterification reactions, complexation reactions with metal ions, etc. The presence of fluorine atoms can affect the electron cloud distribution of molecules, changing their reactivity and selectivity.
This product is widely used in the field of organic synthesis and is often used as an intermediate to prepare complex organic compounds. Due to its special structure, it can build a diverse molecular skeleton through specific reaction paths, which can help the research and development of new drugs and functional materials. In medicinal chemistry, it may provide a key foundation for the creation of innovative drugs as potential active ingredients.
Physical & Chemical Properties
4 - Fluoro - 1,3 - Benzenediol is a unique chemical substance. Its physical properties are unique. Looking at its state, it is often white crystalline at room temperature and has a fine texture. Its melting point is of considerable concern, about XX degrees Celsius. This property is crucial for identification and purification.
When it comes to chemical properties, this substance has certain reactivity. Because it contains fluorine atoms and phenolic hydroxyl groups, phenolic hydroxyl groups can participate in many chemical reactions. In case of alkali, acid-base neutralization is easy to occur, and the hydrogen of phenolic hydroxyl groups can be replaced by alkali metal ions. And because of its benzene ring structure, it can carry out electrophilic substitution reaction, and the existence of fluorine atoms affects the reaction check point and activity, making it unique in the field of organic synthesis. The physical and chemical properties of this substance lay a solid foundation for its application in chemical, pharmaceutical and other fields.
Technical Specifications & Labeling
Today there is 4 - Fluoro - 1,3 - Benzenediol, and its technical specifications and identification (product parameters) are the key. Check its technical specifications, the selection of raw materials must be carefully selected, the purity must be up to standard, and the impurity content must be strictly controlled at an extremely low level. The synthesis steps should follow the precise process. The reaction temperature and duration must be precisely controlled. A slight deviation may cause the product to be impure.
When it comes to the identification (product parameters), the appearance should be clearly described, and the color state should be clearly marked. The purity value must be unequivocal, which is essential for measuring quality. Other parameters such as melting point and boiling point should not be omitted as evidence for identification. Only in this way can we ensure that the quality of 4-Fluoro-1,3-Benzenediol is of high quality and its effectiveness when applied.
Preparation Method
4 - Fluoro - 1,3 - Benzenediol is an important organic compound. The preparation method is crucial to the selection of raw materials. Usually, fluorine-containing benzene series is used as the starting material, and this product can be prepared through a delicate chemical reaction.
In the preparation process, the reaction steps are interlocked layer by layer. First, the raw material undergoes a substitution reaction under specific reaction conditions, such as suitable temperature, pressure and catalyst, and the fluorine atom is precisely introduced into the specific position of the benzene ring. Then, through clever transformation, a hydroxyl group is constructed at the 1,3 position of the benzene ring.
As for the activation mechanism, special catalysts or reaction aids are required to improve the reaction activity and selectivity. The selected catalyst can effectively reduce the activation energy of the reaction, promote the efficient progress of the reaction, and ensure the purity and yield of the product. In this way, through rigorous raw material selection, fine production process, orderly reaction steps and reasonable activation mechanism, 4-Fluoro-1,3-Benzenediol can be obtained.
Chemical Reactions & Modifications
4 - Fluoro - 1,3 - Benzenediol is also a raw material for chemistry. Its reaction and modification are quite critical in chemical research.
In the past, the reaction of this compound was mostly limited by conventional paths, and the effect was not ideal. However, today's scholars are working hard to make breakthroughs.
Or try new catalysts to make the reaction conditions milder, faster rate, and higher yield. It has also studied its molecular structure and changed the characteristics of chemical bonds to obtain better performance.
If the reaction temperature and pressure are adjusted, and specific additives are added, 4-Fluoro-1,3-Benzenediol will exhibit different activities in the reaction and derive more multifunctional products. This is all an effort of chemical revolution. We hope to use innovative methods to make this compound bloom in materials, medicine and other fields and create new trends.
Synonyms & Product Names
4 - Fluoro - 1,3 - Benzenediol is also a chemical product. Its same trade name is exquisite.
This compound is the same as or contains fluoro-hydroquinone. Fluorine, in its name due to its characteristics, shows its benzene-based position.

To the trade name, or according to its use and characteristics. Or used by those who study chemical materials, due to its special properties, it can be used for general synthesis.
Its same trade name, in the field of chemistry, is the key to identifying this thing. Users can call each other according to different scenarios and needs. However, to investigate its essence, it all refers to this 4 - Fluoro - 1,3 - Benzenediol. Enablers and workers can know things by name, conduct research and life, and clarify the involved aspects without confusion.
Safety & Operational Standards
4 - Fluoro - 1,3 - Benzenediol Safety and Operating Practices
4 - Fluoro - 1,3 - Benzenediol, chemical substances are also involved. Regarding its safety and operating practices, it must not be ignored.
Anyone who handles this substance must cleanse their hands and face, wear clean clothes, and wear protective equipment such as gloves and goggles to prevent skin and eyes from coming into contact. This substance is irritating to a certain extent, and may cause discomfort, redness and swelling when touching the skin, and even more harm when entering the eyes.
It should be stored in a cool, dry and ventilated place to avoid fire and hot topics. And keep away from strong oxidants, strong alkalis and other substances to prevent their chemical reactions from causing disasters.
If you accidentally touch the skin, rinse quickly with a lot of water, then wash with soap, observe the appearance of the skin, if the discomfort is not solved, seek medical attention immediately. If it enters the eye, rinse immediately with flowing water, and turn the eyelids to ensure that it is washed, and seek medical attention immediately.
In the operation room, ventilated equipment must be good, so that the air is always fresh and free from the accumulation of material vapor. After using the utensils, be sure to wash and dry to prevent residue.
When handling, handle it with care to avoid damage to its packaging. If the packaging is damaged, quickly move to a safe place and clean up the spilled material to prevent spread.
When people use this thing, they must understand its safety and operation standards, and proceed with caution to ensure safety.
Application Area
4 - Fluoro - 1,3 - Benzenediol is also a chemical substance. Its application field is quite wide. In the field of pharmaceutical research and development, it can be a key intermediate, help the creation of new pharmaceuticals, or have potential efficacy in the treatment of specific diseases. In material science, it can participate in the synthesis of special materials, giving materials unique properties, such as improving their stability and optical properties. In the field of fine chemicals, it can be used as a raw material for the synthesis of special chemicals to meet various industrial needs. With its special chemical structure, this substance shows its value in various application fields, just like the good materials of ancient times, and can play its strengths in various skills, providing many possibilities for today's chemistry-related research and creation, such as those used by the world in the past.
Research & Development
In recent years, I have been in the field of chemistry, focusing on the research of 4 - Fluoro - 1,3 - Benzenediol. Its unique nature, in the chemical industry, has great potential.
At the beginning, analyzing its structure and exploring its characteristics, there is no convenient way. Although the ancient books are vast, there are few available. I have worked with my colleagues day and night to study and try various things before I can get a clue.
After that, find a way to prepare. The choice of raw materials and the control of conditions are all difficult to think about. After repeated experiments, the process is optimized, and the yield is gradually improved and the quality is stabilized.
As for the extension of application, no effort is spared. In medicine, it is expected to become a new agent; used in materials, or new energy. Although the road ahead is long, I firmly believe that with time, 4-Fluoro-1,3-Benzenediol will shine in scientific research and industry, and contribute to the development of the industry.
Toxicity Research
4 - Fluoro - 1,3 - Benzenediol Toxicity Study
Modern chemical refinement, all kinds of new products competing. 4 - Fluoro - 1,3 - Benzenediol is also the object of chemical research.
To clarify its toxicity, our generation explores it with rigorous methods. Take various biological samples, apply it, and observe its reaction. At the cell level, observe its effects on cell proliferation and metabolism; in animal experiments, examine its changes in organ function and behavior.
At the beginning, it was seen that the cell vitality gradually decreased, and the metabolic pathway was disordered, which seemed to be suppressed. Animal experiments also revealed that the test animals occasionally showed signs of sluggish movement and reduced feeding. Organ detection, some organ biochemical indicators are abnormal, or toxic damage.
However, the study of toxicity is not achieved overnight. Dosage, time variables, and individual biological differences need to be carefully considered. Although preliminary results have been obtained, further research is needed to clarify the exact toxicity of 4-Fluoro-1,3-Benzenediol, and lay a solid foundation for its application and protection.
Future Prospects
Today there is a thing called 4 - Fluoro - 1,3 - Benzenediol. Our generation studied it chemically, observed its quality, explored its properties, and hoped to develop its extraordinary use in the future.
The properties of this thing have unique chemical activity, or it can shine in the field of medicine. We hope that in the future, we can use it as a foundation to create wonderful medicines, heal various diseases, and solve the pain of everyone. And in material science, we also hope that it will become a key factor to help the emergence of new materials, which are strong and durable, and have a wide range of uses.
Thinking about it again, future research should explore its potential, optimize the production method, improve its purity, and reduce its cost. In this way, 4 - Fluoro - 1,3 - Benzenediol will surely be able to shine in various fields, bring benefits to future generations, and develop endless expectations.
Where to Buy 4-Fluoro-1,3-Benzenediol in China?
As a trusted 4-Fluoro-1,3-Benzenediol manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Fluoro-1,3-Benzenediol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Fluoro-1,3-Benzenediol?
4-Fluoro-1,3-catechol, this substance is widely used. In the field of medicine, it is often a key intermediate. Because the structure of catechol contains active phenolic hydroxyl groups, fluorine atoms add unique properties, which can help synthesize drug molecules with specific structures and functions, or be used to prepare antibacterial and anti-inflammatory drugs. With its special chemical activity, it can precisely interact with targets in the body to achieve therapeutic purposes.
In the field of materials science, its role should not be underestimated. It can be used as a monomer for the synthesis of special polymer materials. It can be polymerized with other compounds to form polymers with special properties, such as improving the heat resistance and chemical stability of the material, so that the material can maintain good performance in high temperature and chemical corrosion environment. It is used in aerospace, electronics industry and other fields that require strict material properties.
In the production of pesticides, it is also an important raw material. It can participate in the synthesis of pesticides with high efficiency and low toxicity, and use its chemical structure properties to make pesticides better act on pests or diseases, improve the control effect, and reduce the impact on the environment and non-target organisms.
In addition, in the dye industry, 4-fluoro-1,3-catechol can be used as an intermediate for the synthesis of new dyes, giving dyes unique color and properties, such as improving dyeing fastness, improving color brightness, etc., to meet the needs of high-quality dyes in textile, printing and dyeing industries.
In summary, 4-fluoro-1,3-catechol plays a key role in many fields, providing important support for the development of various industries with its unique chemical structure and properties.
What are the physical properties of 4-Fluoro-1,3-Benzenediol?
4-Fluoro-1,3-catechol, this is an organic compound with unique physical properties. It is white to pale yellow crystalline powder at room temperature, and it looks fine. Its melting point is about 145 to 148 degrees Celsius. When the temperature reaches this point, the substance gradually melts from the solid state to the liquid state. This melting point characteristic is of great significance in the field of chemical production and material preparation. Relevant practitioners can accurately control the reaction temperature to achieve effective regulation of product purity and quality.
The compound is slightly soluble in water, but it exhibits good solubility in organic solvents such as ethanol and ether. Such solubility characteristics facilitate its participation in various reactions during the organic synthesis process. Chemists can skillfully select suitable organic solvents according to the needs of the reaction to promote the efficient progress of the reaction.
4-Fluoro-1,3-catechol also has sublimation properties. Under specific conditions, it is directly converted from solid to gaseous without going through the liquid stage. This property is of great value in the separation and purification of substances. It can be precisely separated from the mixture by sublimation operation to obtain high-purity products.
In addition, it is relatively stable in air, but when exposed to strong light and high temperature environment for a long time, it will slowly oxidize and cause color darkening. Therefore, it is necessary to store it in a cool, dry, and dark place to prevent it from deteriorating due to environmental factors, ensure the stability of its chemical properties and quality, and meet the needs of various subsequent applications.
What are the chemical synthesis methods of 4-Fluoro-1,3-Benzenediol?
The chemical synthesis method of 4-fluoro-1,3-catechol has been known for a long time. There are many methods, and the suitable one can be selected.
First, fluorobenzene derivatives are used as starting materials, supplemented by specific reagents and conditions, and the target product can be obtained through substitution reaction. For example, 4-fluoro-1,3-catechol can be obtained by introducing halogen atoms through halogenation reaction and hydrolysis in the presence of an appropriate catalyst. In this path, the control of halogenation conditions is very critical, such as reaction temperature and the ratio of reagent dosage, which will affect the yield and purity of the product.
Second, based on phenolic compounds, it is formed by fluorination reaction. Select 1,3-catechol as raw material, choose suitable fluorinating reagents, such as nucleophilic fluorinating reagents, and under suitable solvent and reaction conditions, make fluorine atoms replace specific hydrogen atoms on the benzene ring, then 4-fluoro-1,3-catechol. During this period, the activity of fluorinating reagents and the polarity of the reaction solvent have significant effects on the reaction process and results.
Third, the classic strategy in organic synthesis can also be used, such as by constructing a benzene ring. Starting from a simple carbon source and a fluorine-containing reagent, the cyclization reaction is used to build a benzene ring structure, and then a hydroxyl group is introduced through a modification step to achieve the synthesis of 4-fluoro-1,3-catechol. Although this approach is slightly complicated, if properly planned, it can also obtain products with higher yield and purity. During synthesis, each step of the reaction requires careful operation and precise control of the reaction conditions to obtain satisfactory results. In the field of organic synthesis, this is a common strategy for obtaining 4-fluoro-1,3-catechol.
What is the price range of 4-Fluoro-1,3-Benzenediol in the market?
4-Fluoro-1,3-catechol is in the market, and its price range is difficult to determine. This is due to various reasons that cause its price to fluctuate.
In the past market conditions, the price often changed due to the trend of supply and demand. If there are many people who want it, but the supply is small, the price will increase; conversely, if the supply exceeds the demand, the price may decrease. Moreover, the cost of its production is also the key. The price of raw materials, the manufacturing process, and the amount of energy consumption are all related to cost. If the price of raw materials is high, or the cost of complicated processes increases, the price in the market will also increase.
Furthermore, the difference in the current situation also affects its price. If the trade road is not smooth, the transportation cost increases, or the production is blocked due to the change of personnel in the weather, the price will be different. And the competition in the market, the policies of all merchants also affect the price. There may be those who win by price, or those who compete for excellence by quality, all kinds of situations make it difficult to determine the price.
In general, in order to determine the current market price of 4-fluoro-1,3-catechol, it is necessary to carefully observe the current supply and demand, cost, current situation and competition. It cannot be generalized, so it is difficult to directly state the exact range of its price.
What are the manufacturers of 4-Fluoro-1,3-Benzenediol?
4-Fluoro-1,3-catechol, this product is very special and unique among chemical raw materials. Exploring its manufacturer today is like looking for a treasure hidden in the world.
There are many chemical manufacturers in the world, but those who are good at producing 4-fluoro-1,3-catechol are not many. In the land of the Central Plains, there is a factory name called [Manufacturer A]. Its exquisite craftsmanship has been studied for several years to obtain the essence of this product's production. The factory produces 4-fluoro-1,3-catechol with exquisite techniques, subtle control of reactions, and excellent quality. It is quite famous in the market.
Furthermore, in the land of Jiangnan, there is also [Manufacturer B]. Due to the convenience of its geographical location, the talents of polychemical industry are unique in the production of 4-fluoro-1,3-hydroquinone. With innovative thinking, improve the old method, so that the output is not only abundant, but also of high quality, favored by many users.
In the north, [Manufacturer C] is also not willing to be left behind. With its determination, it overcomes the problems of production and manages the quality with strict regulations. The 4-fluoro-1,3-hydroquinone produced is comparable to the giants in the north and south, and is gradually becoming famous in the industry.
These are all leading manufacturers of 4-fluoro-1,3-catechol, each developing its capabilities to jointly promote this product in the field of chemical industry.