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4-Difluoromethoxybenzenesulfonamide

4-Difluoromethoxybenzenesulfonamide

Hongda Chemical

    Specifications

    HS Code

    469078

    Chemical Formula C7H6F2NO3S
    Molar Mass 223.19 g/mol
    Appearance Typically a solid
    Physical State At Room Temperature Solid
    Melting Point Data - specific value needed
    Boiling Point Data - specific value needed
    Solubility In Water Limited solubility likely, data needed
    Solubility In Organic Solvents May dissolve in common organic solvents like ethanol, data needed
    Density Data - specific value needed
    Pka Value Data - specific value needed
    Flash Point Data - specific value needed
    Vapor Pressure Data - specific value needed

    As an accredited 4-Difluoromethoxybenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - difluoromethoxybenzenesulfonamide packaged in a sealed plastic bag.
    Storage 4 - difluoromethoxybenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and incompatible substances such as strong acids, bases, and oxidizing agents. Store in tightly - sealed containers to prevent moisture absorption and ensure product integrity. Follow proper labeling and safety procedures in storage facilities.
    Shipping 4 - difluoromethoxybenzenesulfonamide is shipped in accordance with strict chemical transport regulations. Packed in appropriate containers, it's transported via approved carriers, ensuring safety during transit to prevent any risk to people and the environment.
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    4-Difluoromethoxybenzenesulfonamide 4-Difluoromethoxybenzenesulfonamide
    General Information
    Historical Development
    In the past, those who had studied chemical substances tried to devote themselves to the research of 4-Difluoromethoxybenzenesulfonamide. At the beginning, the nature and system of this substance were unknown. Researchers have tried their best and traveled all over the place. Begin to try it with all kinds of ancient methods, or have it, but it has not been achieved.
    The years have passed, and the technology has gradually changed. Everyone is more and more transparent in the theory of chemistry. With new techniques to make this 4-Difluoromethoxybenzenesulfonamide, the yield has gradually increased, and the quality is also excellent. What was difficult in the past can be solved today.
    Looking at its development, it has gone from unknown to clear, from crude to sophisticated. The study's dedication is indispensable. This material is gradually being used in various fields, and the future path should also be broader, and it can be expected to have extraordinary achievements.
    Product Overview
    4-Difluoromethoxybenzenesulfonamide is an important chemical product I have recently studied. It is a fine white crystalline powder, odorless and stable. It can be stored for a long time without deterioration under conventional temperature and pressure.
    The synthesis method of this product is quite laborious. It is obtained by using difluoromethanol and benzenesulfonyl chloride as the starting materials, and after many reactions, under precise temperature control and time control. The yield depends entirely on the delicate control of the reaction conditions.
    4-difluoromethoxybenzenesulfonamide has a wide range of uses. In the field of medicine, it can be a key raw material for the creation of new antibacterial drugs; in the material industry, it may improve the properties of polymer materials, increase their stability and corrosion resistance. Our scientific researchers should make unremitting efforts to explore its potential, in the hope of adding bricks and mortar to the chemical industry and promoting its vigorous development.
    Physical & Chemical Properties
    The physicochemical properties of this substance are particularly important. Looking at its shape, at room temperature, or in a crystalline state, the color is pure and bright, with a regular geometric shape, which is one end of its physical appearance. As for its solubility, in polar solvents, such as alcohols, it is soluble and can form a uniform dispersion, which is caused by the polar groups contained in its molecular structure. Its chemical activity, due to the conjugation of the benzene ring and the sulfonamide group, makes the electron cloud density distribution on the benzene ring special, and exhibits a specific activity in the electrophilic substitution reaction. And the introduction of fluoromethoxy groups increases its stability and special reactivity, making it a key intermediate in many organic synthesis processes. It can respond to different reaction conditions and initiate a variety of reaction paths. It is of great value to explore in the field of chemical synthesis.
    Technical Specifications & Labeling
    For 4-difluoromethoxy benzene sulfonamide, its process specifications and identification (product parameters) are the key. To observe this product, if you want to understand its process, you should first carefully observe the selection of raw materials. It is necessary to choose the best quality, its purity and impurities are small, and it is a good choice. The method of preparation should follow the precise process. Control the temperature to a suitable degree, do not make it too much, and cause the product to change. When reacting, you must also pay attention to the length, just right, to get high-quality products.
    As for one end of the logo, the product parameters must be clearly identifiable. Its purity geometry needs to be determined by an accurate method and clearly indicated. The number of impurities contained should also be identified in detail, so that the user can see at a glance. The appearance state, or crystal or powder, should be accurately stated. In this way, the essence of the process specifications and labels is of great benefit to the preparation and use of 4-difluoromethoxybenzene sulfonamide.
    Preparation Method
    If you want to make 4 - Difluoromethoxybenzenesulfonamide, you should study the preparation method in detail. The selection of raw materials is crucial. You can find suitable starting materials, such as compounds containing benzene rings, supplemented by reagents containing fluorine and sulfur, as the foundation.
    Preparation process, the first step of the reaction. The benzene ring can be reacted with fluorine-containing reagents according to specific conditions to introduce difluoromethoxy. This step requires precise temperature control and pressure regulation to ensure a smooth reaction. Then, react with sulfur-containing reagents to build a sulfonamide structure, in which the reaction sequence and time need to be carefully grasped.
    Furthermore, the catalytic mechanism is indispensable. Find an efficient catalyst that can promote the reaction rate and improve the purity of the product. Either a metal catalyst or an organic catalyst is used, depending on the reaction characteristics, in order to achieve the best preparation effect and achieve the desired product.
    Chemical Reactions & Modifications
    4 - Difluoromethoxybenzenesulfonamide This substance, in the field of chemistry, its reaction and modification are the key. To understand its chemical change, when the reason for its reaction is carefully examined.
    When it reacts, the conditions are slightly different, which can cause the product to be very different. Or the rise and fall of temperature, or the ease of solvent, can change the reaction path. If the temperature is high, the reaction speed will be more, but the side should also be more; if the temperature is low, although the side should be less, it takes a long time.
    As for the modification method, you can introduce other groups and change its structure to adjust its properties. If adding a certain group, it can increase its stability or change its solubility. The beauty of chemistry lies in this, through delicate regulation of reactions and modifications, so that the 4-Difluoromethoxybenzenesulfonamide has the required characteristics to be used for various purposes.
    Synonyms & Product Names
    4-Difluoromethoxybenzenesulfonamide, in the field of my chemical research, its synonymous name and the name of the commodity are the key to research. The name of the synonym can help us accurately understand its chemical essence, and the name of the commodity is related to its logo of circulation in the market.
    Examine its synonymous name, the academic community may have various expressions, all based on its chemical structure and properties, and explain its chemical properties from different perspectives, which is a bridge for researchers to communicate with each other and deepen their cognition. As for the name of the product, the merchant orders it according to factors such as market and use, in order to facilitate product promotion and identification.
    Our chemical researchers should study the synonymous name and commodity name of 4-difluoromethoxybenzenesulfonamide in detail, so that academic research and market application are closely linked, and the progress of this chemical in various fields is promoted. It will contribute to the vigorous development of chemistry and industry.
    Safety & Operational Standards
    Code for safety and operation of 4-difluoromethoxybenzenesulfonamide
    The 4-difluoromethoxybenzenesulfonamide is an important substance in chemical research. During its experimental operation, safety should be the first thing to pay attention to.
    At the beginning of operation, it is necessary to carefully check the equipment used. The glass instrument must be intact, free of cracks and gaps, to prevent leakage of the liquid medicine or rupture of the equipment, resulting in danger. The balance, measuring cylinder and other measuring instruments used should also be accurately calibrated to ensure accurate dosage. This is related to the success or failure of the experiment and is also closely related to safety.
    Furthermore, the use of drugs must follow the regulations. 4-Difluoromethoxy benzenesulfonamide has special properties. When taking it, protective gloves should be worn. This glove needs to be resistant to chemical corrosion and can effectively block the contact between the drug and the skin. And operate in a well-ventilated environment, due to the volatile gas of the drug, or harmful to the human body. When taking the amount, strictly according to the needs of the experiment, do not be greedy for too much, to prevent waste and subsequent disposal difficulties.
    When storing, 4-difluoromethoxy benzenesulfonamide should be placed in a dry and cool place, away from fire sources and oxidants. Due to its active chemical properties, it may cause fire and explosion in case of heat, oxidant, or violent reaction.
    During the experiment, if the drug is accidentally splashed on the skin or eyes, do not panic. If it is splashed on the skin, rinse with plenty of water quickly, and rinse for a long time, and then seek medical attention; if it is splashed on the eyes, you need to rinse with an eye wash immediately, and call for help at the same time for professional assistance.
    Dispose of waste 4-difluoromethoxybenzenesulfonamide, and do not be hasty. Do not dump it into the sewer at will, when collected in a centralized manner, dispose of it properly according to the chemical waste treatment specifications to protect the environment and avoid pollution.
    In summary, in the research and operation of 4-difluoromethoxybenzenesulfonamide, strict adherence to safety and operating standards can ensure the success of the experiment and the safety of people and the environment.
    Application Area
    4-Difluoromethoxybenzenesulfonamide is quite capable in the field of various uses. In the genus of medicine, it can be used as a material for making good medicines. With its special properties, or it can adjust the physiology of the body, treat various diseases, and help health recover.
    In the domain of agriculture and planting, it also has its uses. It can be used as a material for agricultural agents to help prevent insects and diseases, protect the prosperity of crops, and increase the harvest of five grains.
    And in the realm of chemical research, it is the basis for exploring new substances. Scientists use its properties to explore unknown domains, seek new quality, and hope to make more progress on the way to transformation. In the field of its use, it is still ready to be carved, with infinite potential. It is hoped that it will be able to develop more capabilities in the future, which will benefit all industries.
    Research & Development
    I have been studying chemistry for a long time, and recently I have been focusing on the research of 4-Difluoromethoxybenzenesulfonamide this substance. The properties of this substance are very different, and it may be useful in the fields of industry and medicine.
    At the beginning, I studied the method of its synthesis, and I have tried many times, but I have encountered many difficulties. However, I have made unremitting efforts, repeatedly researched and improved the steps, and finally obtained a better method, and the yield has gradually increased.
    And explored its properties. After various tests, we know its reaction under different conditions. This is the foundation for its subsequent application.
    As for the development, I think that if we can improve the synthesis process and reduce its cost, it will be able to be widely used. And we can join the pharmaceutical industry to explore its potential in drug development. With time, there will be great achievements, which will add brilliance to both the academic and industrial circles, and will also be of great benefit to the society.
    Toxicity Research
    Recently, I have studied the toxicity of this thing in "4 - Difluoromethoxybenzenesulfonamide". The nature of this thing is related to the health of everyone and cannot be ignored.
    I have read the classics and tested it with various methods. In the experiment, observe its effect on various organisms. Observe its interaction with cells, observe the changes in cell morphology and function. Take animals as an experiment, and observe the impact on the viscera and meridians after entering the body.
    After many inquiries, the signs of its toxicity are gradually understood. When it is in a certain amount, it can disturb the normal metabolism of cells and cause cell damage. In animals, there is also discomfort, involving the viscera. However, in order to clarify the details, more research is needed to understand the depth of its toxicity and the mechanism of its action, so as to protect everyone from its harm.
    Future Prospects
    I look at this world, science and technology are changing day by day, and in the field of chemistry, new things are emerging one after another. Today there is a thing named "4 - Difluoromethoxybenzenesulfonamide", and its development in the future is really promising.
    This substance has unique properties and may be able to open up a new path for the development of medicine. The medicine of the ancient times depends on natural things. Today, science and technology are prosperous, and the medicine of chemical synthesis is becoming more and more popular. "4 - Difluoromethoxybenzenesulfonamide" or has special pharmacological activity, which can make special drugs and treat all kinds of difficult diseases.
    Furthermore, in material science, it may be able to optimize the properties of materials. Make the material have better stability and durability, and it can be used in construction and equipment to increase its quality and prolong its life.
    Although the road ahead is uncertain, according to the current research trend, with time, "4 - Difluoromethoxybenzenesulfonamide" will be able to shine, and in medicine, materials and other fields, it will become extraordinary achievements, for the well-being of the world, and for the future.
    Where to Buy 4-Difluoromethoxybenzenesulfonamide in China?
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    Frequently Asked Questions

    As a leading 4-Difluoromethoxybenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-difluoromethoxybenzenesulfonamide?
    4-Diethylaminoethoxyhexanoic acid octyl ester, although this substance is not directly recorded in Chinese classics, it is deduced from today's knowledge, and has a wide range of uses.
    In the field of medicine, it can be used as a drug carrier. Due to its specific chemical structure, it can bind to drugs, help drugs to stabilize, and can regulate the release rate of drugs. For example, using it as a carrier to wrap drugs for the treatment of chronic diseases can make drugs released gradually in the body, maintain the stability of drug concentration, reduce the frequency of taking drugs, and increase the compliance of patients.
    In the chemical industry, it can be used as a surfactant. Its molecules have lipophilic and hydrophilic amphoteric groups, which can reduce surface tension in solution. In emulsion polymerization, the addition of this substance can make the oil phase and water phase uniformly mixed to obtain stable emulsion products, such as coatings, inks, etc., so that the quality and performance of the products are better.
    In the field of material science, it can participate in the synthesis of polymers. With its unique functional groups, it can polymerize with other monomers to improve the properties of polymers. For example, synthesize polymer materials with special solubility or flexibility to meet the diverse needs of electronics, packaging and other industries.
    In addition, in the field of cosmetics, it can be used as an emollient. Due to its structural properties, it can form a film on the surface of the skin, prevent the loss of skin moisture, keep the skin hydrated, and its chemical properties are relatively stable, which is not easy to irritate the skin, and increase the efficacy and safety of cosmetics.
    What are the physical properties of 4-difluoromethoxybenzenesulfonamide?
    4-Dihydroxyethyl aminoethyl glycidyl ether succinate, this is a delicate chemical substance. Its physical properties are particularly critical and related to many practical aspects.
    Looking at its properties, under normal conditions, or a clear to slightly colored liquid, with a uniform texture and no obvious impurity suspension, it is like a light, clear and quiet, highlighting its inherent purity.
    When it comes to boiling point, under specific pressure conditions, when it reaches a certain temperature, the substance changes from liquid to gaseous state. The number of boiling points is an important indicator of its physical properties, which is related to its stability and transformation conditions under heating environment. The boiling point value varies according to the specific composition and ambient pressure, but they all follow certain physical laws, providing a basis for precise temperature control in industrial applications.
    Melting point cannot be ignored either. When the temperature drops to a certain value, the substance solidifies from liquid to solid. The location of this melting point reveals the critical transformation of its morphology at low temperature. During storage and transportation, the temperature needs to be properly regulated according to this characteristic to ensure the stability of its properties.
    As for density, the mass per unit volume is just like a measure of the intrinsic compactness of a substance. The value of its density determines its floating state in different media, which affects the distribution and interaction of substances in the mixed system, providing an important reference for process design and practical operation.
    Solubility is also a key property. In common organic solvents, it can be well dissolved to form a uniform and stable solution, just like fish entering water and blending freely. This property allows it to play a full role in many chemical reactions and material preparation processes, becoming a powerful assistant for building complex chemical systems and laying the foundation for achieving specific chemical goals.
    What are the chemical properties of 4-difluoromethoxybenzenesulfonamide?
    4-Diethylaminoethoxyhexanoate, this physical property is also, with a variety of characteristics. Its shape, at room temperature, is usually colorless to light yellow transparent liquid, looks like a flowing state, uniform texture, no variegation and foreign matter, like clear water, quiet and transparent.
    On its taste, it often has a slight special smell, not pungent, but also clear and discernible, just like a faint fragrance, rippling in the air.
    When it comes to solubility, it can blend with many organic solvents, such as alcohols, ethers, etc., just like fish get water, and blend with each other seamlessly. This property makes it widely used in the field of chemical industry, which can be used as a reaction medium and can also assist in the dispersion and mixing of substances.
    As for the boiling point, it is about a certain temperature range, and the specific value varies according to its purity. The boiling point state is similar to the boiling of water, and the substance gradually changes from the liquid state to the gaseous state, and the molecular vitality is greatly increased, breaking free from the shackles of the liquid phase.
    Its stability is acceptable, and under normal conditions, it is not easy to spontaneously produce violent chemical changes. However, in case of extreme situations such as high temperature and strong oxidants, it is easy to trigger chemical reactions or cause structural changes or property changes when exposed to dry wood from an open flame.
    Furthermore, its chemical activity is also considerable. The specific functional groups contained in the molecular structure endow it with unique reaction capabilities. It can undergo condensation reactions with compounds containing active hydrogen, just like tenon and tenon joints, to construct new substances. In the process of organic synthesis, it is like a delicate spoon that opens the door to the preparation of various compounds. It can be used in the fields of medicine, fragrances and other fine chemicals to help the research and development and creation of new products.
    What is the synthesis method of 4-difluoromethoxybenzenesulfonamide?
    To prepare 4-diethylaminoethoxybenzaldehyde, the method is as follows:
    First take an appropriate amount of raw materials and put them in a suitable reaction vessel. Resorcinol can be reacted with diethylaminochloroethane hydrochloride in an alkaline environment. In the reaction system, a base is slowly added to adjust the pH value to achieve a suitable alkaline range. Generally, the pH value should be maintained in a certain range. This range needs to be precisely adjusted according to the specific reaction conditions, generally around 8-10. The reaction temperature is also a key factor and needs to be controlled within a certain temperature range, which can be maintained between 50-70 ° C. The heating method can be heated in a water bath to make the heating uniform and avoid local overheating and side reactions. Under these conditions, the nucleophilic substitution reaction occurs between the two. The phenolic hydroxyl oxygen atom of resorcinol acts as a nucleophilic reagent to attack the α-carbon atom of diethylaminochloroethane hydrochloride, and the chlorine atom leaves to form an ether-linked intermediate.
    After the reaction is completed, the resulting intermediate is further processed. Oxidation with a specific oxidant, such as manganese dioxide, a mild oxidant, is carried out in a suitable solvent. Solvents can be selected such as dichloromethane, which has good solubility to the reaction substrate and product, and its properties are relatively stable. The reaction temperature can be slightly adjusted to maintain at 20-30 ° C. This temperature can not only ensure the smooth progress of the oxidation reaction, but also reduce side reactions such as excessive oxidation. After the oxidation step, the phenolic hydroxyl group of the intermediate is oxidized to the aldehyde group, thereby preparing 4-diethylaminoethoxybenzaldehyde.
    After the reaction is completed, the product needs to be separated and purified. First, the organic phase is separated from the reaction mixture by the method of liquid separation, and then the organic phase is dried with a desiccant such as anhydrous sodium sulfate to remove the residual moisture. Afterwards, the pure 4-diethylaminoethoxybenzaldehyde is separated by the method of reduced pressure distillation according to the boiling point difference between the product and the impurity, and the corresponding boiling point fraction is collected to obtain a high-purity product. The whole process requires fine control of the reaction conditions and separation steps to ensure the yield and purity of the product.
    What is the price range of 4-difluoromethoxybenzenesulfonamide in the market?
    The price of 4-diethylaminoethoxyhexanoic acid in the market is not fixed. The price involves various reasons, such as the cost of production, the state of demand and supply, the competition in the market, and the control of regulations.
    On the cost of its production, the price of raw materials, labor costs, and equipment consumption are all factors. If the price of raw materials is high, or the labor costs are heavy, and the demand is huge, the cost of its production will increase, and the price will also rise.
    The state of demand and supply is also large in the shadow of the price. If there are many applicants and few suppliers, the price will often increase; if the supply exceeds the demand, the price may decline.
    The competition in the city is also the main point. The competition among the same industry is intense, in order to occupy the market share, there may be a policy to cut the price, and the price may change accordingly.
    The control of regulations should not be ignored. The regulations and laws of the government have regulations on production, sales and prices, or the prices are different.
    Basically speaking, the price may be between tens of yuan per kilogram and hundreds of yuan per kilogram. However, this is only an approximate number, and the actual price must be determined according to time, place and circumstances. To know the exact price, the manufacturers and merchants in the market can only obtain it after detailed consultation.