4-Cyano-3- (trifluoromethyl) iodobenzene, this substance has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
First, it plays an important role in the formation of carbon-carbon bonds. For example, palladium-catalyzed cross-coupling reactions, such as Suzuki reaction and Heck reaction, interact with various olefins, arylboronic acids and other reagents to effectively build complex aromatic compounds. This is of great significance in pharmaceutical chemistry. The construction of the core skeleton of many drug molecules often relies on this method to precisely introduce specific functional groups, laying the foundation for the development of new drugs.
Second, in the field of materials science, it also has applications. With its unique electronic properties and structural characteristics, it can participate in the synthesis of materials with special photoelectric properties. For example, the synthesis of materials for organic Light Emitting Diodes (OLEDs) or solar cells, after structural modification and optimization, it is expected to improve the performance indicators of materials such as charge transfer efficiency and luminous efficiency, and then promote the progress of related material technologies.
Furthermore, in the synthesis of fluorine-containing compounds, due to the fact that the molecule contains both cyanide groups and trifluoromethyl groups, both of which are highly active functional groups, which can be derived through a series of chemical reactions. In this way, more fluorinated compounds with novel structures and unique properties can be prepared, and fluorinated compounds often exhibit excellent biological activity and stability in fields such as pesticides and medicine.

4-Cyano-3- (trifluoromethyl) iodobenzene, also an organic compound. It has specific physical properties and is described below.
First of all, its appearance, under room temperature and pressure, this substance is mostly white to light yellow solid, its color is pure, the texture is fine, under light, or there is a shimmer flicker.
The melting point is about 82-86 ° C. When the temperature gradually rises to this point, the substance slowly melts from a solid state to a liquid state. This process is smooth and orderly. When the phase changes, the intermolecular forces gradually change, showing the transformation of the material state.
As for the boiling point, under a specific pressure environment, it is about 277.9 ° C. At this temperature, the thermal motion of the molecule intensifies, breaks free from the shackles of the liquid phase, and converts into the gas phase, reflecting the change of its physical state under the thermal effect.
Solubility is also an important physical property. It is insoluble in water, and water is also a solvent composed of polar molecules, while 4-cyano-3- (trifluoromethyl) iodobenzene molecules have weak polarity, so it is difficult to dissolve with water. However, it is soluble in organic solvents such as dichloromethane, chloroform, and tetrahydrofuran. In such solvents, the molecules can be uniformly dispersed to form a uniform and stable system.
The density of this compound, under certain conditions, shows a specific value, and its density reflects the degree of intermolecular packing, which is closely related to molecular structure, atomic weight and other factors.
In addition, the vapor pressure of the substance changes at different temperatures, and the temperature increases, and the vapor pressure gradually increases, reflecting the tendency of molecules to escape from the liquid phase to the gas phase.
The above physical properties are the key to the understanding and application of 4-cyano-3- (trifluoromethyl) iodobenzene, and are of great significance in many fields such as organic synthesis and materials science.

4-Cyano-3- (trifluoromethyl) iodobenzene is an important intermediate in organic synthesis. Its synthesis method is very critical and is related to the progress of organic synthesis.
One method is to use benzene derivatives containing cyanide groups and trifluoromethyl groups as starting materials and obtain them by halogenation reaction. First, take a specific benzene derivative, whose molecular structure already contains cyanide groups and trifluoromethyl groups, which have specific substitution positions on the benzene ring. When placing this derivative under the conditions of halogenation reaction, the halogenation reagent used needs to be carefully selected. Take the iodine source as an example, such as the iodine element with appropriate catalysts and reaction aids. In a suitable reaction solvent, the reaction temperature, time and other conditions are controlled to make the iodine atom replace the hydrogen atom at a specific position on the benzene ring to synthesize 4-cyano-3- (trifluoromethyl) iodobenzene. In this process, the polarity of the reaction solvent, pH and other factors all affect the rate and selectivity of the reaction, so fine regulation is required.
Another method is to construct its structure through a multi-step reaction. The starting material may be a benzene compound containing only a cyanide group, and the trifluoromethylation reaction is carried out first. This reaction may require special trifluoromethylation reagents, such as some organometallic reagents containing trifluoromethyl or other activated trifluoromethyl sources. In an appropriate reaction system, trifluoromethyl is successfully introduced into the benzene ring to obtain an intermediate containing cyanyl and trifluoromethyl. Then, the intermediate is iodized, and the reaction conditions are also optimized according to the principle of halogenation reaction, so that the iodine atom accurately replaces the hydrogen at the target position, and 4-cyano-3- (trifluoromethyl) iodobenzene is finally obtained. This multi-step synthesis method, although the steps are slightly complicated, requires a high degree of control of the reaction conditions and purification of the intermediate product. The selectivity of each step can be used to accurately construct the structure of the target molecule.
Furthermore, there is also a synthesis path catalyzed by transition metals. Select suitable transition metal catalysts, such as complexes of metals such as palladium and copper. The reaction occurs under transition metal catalysis with a substrate containing cyanogen and trifluoromethyl group and an iodine source. The catalyst can activate the substrate molecule and the iodine source, reduce the activation energy of the reaction, and promote the transfer of iodine atoms to the target benzene ring position. In this process, the ligand structure of the catalyst has a great influence on the activity and selectivity of the reaction. It is necessary to rationally design and screen the ligand according to the characteristics of the substrate to achieve the purpose of efficient synthesis of 4-cyano-3- (trifluoromethyl) iodobenzene. And the alkali, solvent and other factors in the reaction system also need to be carefully considered to optimize the reaction conditions and improve the yield and purity of the product.

4-Cyano-3- (trifluoromethyl) iodobenzene is a chemical commonly used in organic synthesis. When storing and transporting, many matters must be paid attention to.
First storage, this substance should be stored in a cool, dry and well-ventilated place. Because of its certain chemical activity, high temperature and humid environment can easily cause it to deteriorate. Under high temperature, or the activity of chemical bonds in the molecule intensifies, triggering reactions such as decomposition; in humid environment, moisture may react chemically with the substance, destroying its chemical structure and causing it to lose its original chemical properties. Therefore, it is necessary to choose a suitable storage temperature and humidity. Usually, the temperature should be controlled between 2-8 ° C, and the humidity should not exceed 60%.
In addition, when storing, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed. This is because the cyano, trifluoromethyl and iodine atoms of 4-cyano-3- (trifluoromethyl) iodobenzene can chemically react with the above substances. If it encounters with an oxidant, or has a violent oxidation reaction, it can even cause serious accidents such as fires and explosions; when interacting with acids and bases, it will also change its chemical structure and affect its performance.
As for transportation, be sure to ensure that the packaging is complete and well sealed. If the package is damaged, the substance or leakage will not only pollute the environment, but also pose a threat to the transportation personnel. Because of its toxicity and irritation, human contact or inhalation can cause health damage. During transportation, it is also necessary to protect against exposure to the sun, rain, and high temperature. Driving should be stable to avoid violent vibrations and collisions to prevent package rupture.
In short, when storing and transporting 4-cyano-3- (trifluoromethyl) iodobenzene, it is necessary to strictly abide by relevant norms and requirements, and be careful from the control of the storage environment to the operation of the transportation process, so as to ensure its quality and safety and avoid accidents.

4-Cyano-3- (trifluoromethyl) iodobenzene, the price of this substance in the market is difficult to generalize. The change in its price is affected by various factors.
The first to bear the brunt is the difficulty of preparation. The process of synthesizing this compound may be complex or simple, and the materials used may be thin or common, all of which are related to cost. If the preparation requires special methods and rare materials, the price will be high; on the contrary, if the process is simple and the materials used are widely available, the price will be low.
Furthermore, the state of market supply and demand is also the main reason. If there are many people seeking, but there are few producers, and the supply is in short supply, the price will rise; if there are more and less products, the supply will exceed the demand, and the price will fall.
In addition, the manufacturer's brand and product purity also affect its price. If the famous factory produces, or the quality is excellent and the reliability is high, the price may be higher than that of other factories; if the purity is high, the price will be different due to the difficulty of purification.
Looking at the market in the past, the price fluctuates widely. At some time and place, or due to changes in raw materials and processes, the price per gram can reach hundreds of gold; and elsewhere, due to market competition and production capacity, the price may drop to tens of gold per gram.
In summary, in order to know the exact market price, it is necessary to carefully observe the real-time market conditions, supply and demand conditions, and the reports of various suppliers in order to obtain a more accurate number.