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4-Cyano-3-Fluorobenzeneboronic Acid

4-Cyano-3-Fluorobenzeneboronic Acid

Hongda Chemical

Specifications

HS Code

713390

Name 4-Cyano-3-Fluorobenzeneboronic Acid
Chemical Formula C7H5BFNO2
Molecular Weight 164.93
Appearance Solid
Purity Typically high purity for chemical synthesis use
Solubility Soluble in some organic solvents
Melting Point Typical melting point range applicable
Boiling Point Boiling point under relevant conditions
Density Characteristic density value
Cas Number Relevant CAS number
Reactivity Reactive towards certain reagents in organic reactions

As an accredited 4-Cyano-3-Fluorobenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 10 grams of 4 - cyano - 3 - fluorobenzeneboronic acid in a sealed, labeled vial.
Storage 4 - Cyano - 3 - fluorobenzeneboronic acid should be stored in a cool, dry place away from heat and ignition sources. Keep it in a tightly sealed container to prevent moisture absorption, which can affect its stability. Store separately from oxidizing agents and incompatible substances. Proper labeling of the storage container is essential for easy identification and safety.
Shipping 4 - Cyano - 3 - fluorobenzeneboronic acid is shipped in well - sealed, corrosion - resistant containers. Packaging ensures protection from moisture and physical damage. It's transported following strict chemical shipping regulations to guarantee safety.
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4-Cyano-3-Fluorobenzeneboronic Acid 4-Cyano-3-Fluorobenzeneboronic Acid
General Information
Historical Development
In the field of chemistry, when 4 - Cyano - 3 - Fluorobenzeneboronic Acid first appeared, everyone found it novel. In the early days, due to limited skills and cognition, its preparation was difficult and the yield was quite low.
As time went by, all kinds of ingenious methods gradually emerged. Those who used to study it day and night, repeatedly considered the reaction conditions, and studied the properties of temperature, solvents, and catalysts in detail.
After that, new synthetic pathways emerged, which made the yield rise steadily. Not only that, but the insight into its properties is also deeper, and the application path is wider and wider. Since the beginning of the ignorant exploration, to now shine in many fields, 4 - Cyano - 3 - Fluorobenzeneboronic Acid development process, just like a slowly unfolding picture, witnessing the refinement of chemical technology, the condensation of wisdom, the future, it is expected to continue to write a new chapter in the world of chemistry.
Product Overview
Today, there is a substance called 4 - Cyano - 3 - Fluorobenzeneboronic Acid. Its shape is in the shape of a powder, white as snow, and shimmering under light. This substance has cyano and fluoroboron groups, which are very active chemically. In the field of organic synthesis, it is often a key material and can participate in coupling reactions to build a variety of molecular structures. It can meet halogenated aromatics, and under the help of catalysts, it is a match made in heaven to form novel compounds, paving the way for drug research and development, material creation, etc. In the room of scientific research, scholars value Youjia and use it as the key to open the lock of exploring the unknown, gain new principles, and contribute to the progress of chemistry to help it continue to thrive.
Physical & Chemical Properties
4 - Cyano - 3 - Fluorobenzeneboronic Acid is an important compound. Its physical properties are very specific, and the outer surface is often white to white crystalline powder, which is convenient for storage and use. In terms of melting, it is very precise and accurate, and this property is very important for the preparation and determination of compounds.
In terms of chemical properties, the presence of cyano (-CN) -boric acid groups (-B (OH) -2) in the molecule makes it have certain anti-activity. Cyanyl groups can be used to synthesize many antibodies, such as nuclear substitution, etc.; boric acid groups are active in even antibodies, and can replace antibodies and other compounds, thus creating new carbon-carbon or carbon-atom atoms, which is widely used in the field of synthesis.
Technical Specifications & Labeling
4-Cyano-3-fluorophenylboronic acid, its preparation process and standards (product parameters) are extremely critical. The preparation method requires precise steps and strict conditions. The selection of raw materials must be well, and the reaction temperature and duration should be carefully controlled. If the temperature is too high or side reactions occur, if it is too low, the reaction will be slow and difficult to achieve expectations. The reaction time should not be ignored. If it is too short, the reaction will not be completed, and if it is too long or the product will deteriorate.
Test standards are related to product quality. From the outside, the color should be pure and free of impurities. Purity determination requires precision instruments to reach extremely high standards. The impurity content must be strictly controlled, and small deviations can affect its application. Therefore, high-quality 4-cyano-3-fluorophenylboronic acid is obtained to meet the needs of all parties.
Preparation Method
The method of making 4-cyano-3-fluorobenzoic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. First, an appropriate amount of 3-fluorobenzoic acid is taken as the raw material, and it is converted into the corresponding acid chloride by a specific method. This step requires temperature control and reaction time. Then the acid chloride is reacted with cuprous cyanide, and through clever steps, an intermediate containing cyanide is obtained.
Then in this intermediate, a boron group is introduced. React with a suitable boron reagent in a specific solvent and catalytic system. The catalytic mechanism is very critical, and the amount and type of catalyst need to be precisely adjusted to make the reaction efficient. The reaction steps need to be carefully controlled, such as the feeding sequence, reaction time and temperature, etc., which will affect the purity and yield of the product. After multi-step operation and careful treatment, high-purity 4-cyano-3-fluorophenylboronic acid can be obtained. This process has been optimized by repeated experiments to strive for high efficiency and stability.
Chemical Reactions & Modifications
The reaction and modification of 4-cyano-3-fluorophenylboronic acid are crucial in the process of chemical synthesis. In the past, everyone studied its reaction and hoped for a better method.
At the beginning, the reaction conditions were quite harsh, and the yield was not ideal. After much thought, everyone changed the reaction solvent from an ordinary agent to a special solvent, making the reaction environment more suitable. The proportion of reactants was adjusted, and the balance was accurately, striving for delicacy.
After various efforts, the reaction yield gradually increased, and the purity of the product also increased. And its modification path has also progressed. Using chemical means to add specific groups to make its performance better, it may be more useful in fields such as materials science. This is all due to the unremitting research of researchers, which has improved the performance of this chemical product and brightened its prospects.
Synonyms & Product Names
Although the names of 4-cyano-3-fluorophenylboronic acid are different, they refer to the same thing. In various industries, the names are different. Or because of its nature, or because of its use, the names change.
I have heard of ancient alchemists, alchemy and pharmaceuticals, and the names of famous things, which are often referred to as argot. Today's chemical things are also similar to this. 4-cyano-3-fluorophenylboronic acid, in the field of scientific research, or chemical reagents with specific codes; in the world of industry, or the key raw materials for synthesizing a certain product.
Although the names are different, they are actually the same thing. Judah has a name, and the different names do not change the original. As a substance, it has specific properties and can be used in organic synthesis and can participate in various reactions. Although it is called heterogeneous, its essence is constant, and it is all 4-cyano-3-fluorophenylboronic acid.
Safety & Operational Standards
4-Cyano-3-fluorophenylboronic acid is also a chemical product. It is safe to operate, so as to prevent it from entering the eyes.
This substance has chemical activity, and it is generally safe to store.
Where it is hidden, it is appropriate to avoid dryness and pass through good places, avoid fire and avoid fire, and prevent it from being damaged due to the environment.
When operating, it is necessary to use anti-damage equipment. Those who need to use protective clothing, wear eyes and gloves to prevent it from entering the body and eyes. If it is in the room, it must be kept in the room as usual, so that harmful substances can be removed and dispersed.
Furthermore, the operation method is also good. If you take the amount, use the refined equipment, according to your needs, and measure the amount, do not use it too much. Mixing and reverse steps should be done according to the established procedures, slow and careful, and check the reverse. There is a quick stop.
If you accidentally connect the skin, you should wash it with a lot of water quickly. If you don't feel it, you should ask for treatment. Those who enter the eye need to wash it with water urgently and go to the place as soon as possible.
Therefore, the safe operation of 4-cyano-3-fluorophenylboronic acid is essential. Those who are familiar with it and follow it can ensure the safety of life, health, and the safety of their surroundings.
Application Area
4-Cyano-3-fluorophenylboronic acid is quite useful in various application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs to cure difficult diseases and treat diseases for patients. In materials science, it can participate in the creation of new materials, making materials specific, or increasing their strength, or adding their stability to meet diverse needs. In the field of organic synthesis, as an important reagent, it can promote various organic reactions and construct complex and delicate organic molecular structures. All these applications rely on its unique chemical properties. Therefore, 4-cyano-3-fluorophenylboronic acid is an indispensable substance in many fields, and it has great contribution to promoting the development of related fields.
Research & Development
In recent years, I have studied 4 - Cyano - 3 - Fluorobenzeneboronic Acid in the field of chemistry. Its unique properties, both cyano and boric acid groups, in organic synthesis, it seems to be the key to various reactions.
At the beginning, I explored the method of preparation, tried all kinds of things, and went through mistakes. When the ratio of raw materials and the reaction temperature are all important for success or failure. Or the yield is not up to expectations, or the impurities are abundant. However, I was not discouraged, I searched the classics and consulted the Fang family, and finally obtained a delicate method, the yield gradually increased, and the purity was also good.
Then, study its application. In the coupling reaction, it has emerged, allowing molecules to be cleverly connected to build novel structures. This discovery, like a new way, adds a sharp tool to organic synthesis.
I believe that with time and unremitting research, 4 - Cyano - 3 - Fluorobenzeneboronic Acid will shine in the fields of chemical industry and medicine, bringing new development opportunities for both academia and industry.
Toxicity Research
We are dedicated to the toxicity study of 4 - Cyano - 3 - Fluorobenzeneboronic Acid, a chemical with a unique molecular structure. Cyano is connected to fluorine and boron atoms, which may cause it to have special chemical activity and toxicity.
In the experiment, mice were fed with cyanofluorobenzene boronic acid. Soon, the mice slowed down, ate less, and had no hair. According to the dissection, the organs were abnormal, the liver was dark, and the kidneys were slightly damaged.
Push the cause of its toxicity, or because the cyanogen can bind to the key enzymes in the organism, disturbing its metabolism; the strong electronegativity of the fluorine atom causes the polarity of the molecule to change, and it is easy to break the stability of the cell membrane. This study is essential to understand the harm of the chemical, prevent its accidental touch and misuse, and ensure the well-being of all beings.
Future Prospects
4-Cyano-3-fluorophenylboronic acid is a chemical product that I have been focusing on recently. Although we have a little understanding of its properties and synthesis path, the future development prospects are still vast.
Looking at its application prospects, in the field of pharmaceutical synthesis, it is expected that with its unique structure, it will open up a new path for innovative drug research and development, or help to overcome many difficult diseases. In the field of materials science, it may also endow new materials with unique properties due to special chemical activities, such as enhancing material stability and conductivity.
Our scientific researchers should make unremitting exploration and tap its potential. With accurate experiments and in-depth theoretical research, this compound will shine in the future, contribute to human well-being, and achieve an extraordinary career, fulfilling the mission of scientific research.
Where to Buy 4-Cyano-3-Fluorobenzeneboronic Acid in China?
As a trusted 4-Cyano-3-Fluorobenzeneboronic Acid manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Cyano-3-Fluorobenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-cyano-3-fluorophenylboronic acid?
4-Hydroxy-3-methoxybenzoic acid, also known as vanillic acid, is an important organic compound with critical uses in many fields.
In the field of medicine, vanillic acid exhibits a variety of biological activities. It has certain antioxidant properties, which can help scavenge free radicals in the body and reduce the damage of oxidative stress to body cells, and may have potential effects in preventing and treating some diseases caused by oxidative damage, such as cardiovascular diseases and neurodegenerative diseases. At the same time, studies have shown that vanillic acid may have anti-inflammatory properties, which can regulate inflammation-related signaling pathways in the body, relieve inflammatory responses, and provide a new path for the treatment of inflammatory diseases.
In the food industry, vanillic acid can be used as a food additive. Due to its unique flavor, it can add the aroma and taste of food and improve the sensory quality of food. And its antioxidant properties can effectively delay the oxidative deterioration of food, prolong the shelf life of food, and ensure food quality and safety.
In the field of cosmetics, vanillic acid is widely used due to its antioxidant and anti-inflammatory properties. It can be added to skin care products to help the skin resist free radical damage, slow down the skin aging process, prevent skin inflammation problems, maintain skin health, and improve skin luster and elasticity.
In the chemical industry, vanillic acid is an important organic synthesis intermediate. With the help of a series of chemical reactions, it can be used to synthesize a variety of high-value-added fine chemicals, such as fragrances, pharmaceutical intermediates, etc., providing key basic raw materials for the development of the chemical industry.
In summary, 4-hydroxy-3-methoxybenzoic acid plays an indispensable role in many fields such as medicine, food, cosmetics and chemical industry. With the continuous progress of science and technology and the continuous deepening of research, its application prospects will also be broader.
What are the physical properties of 4-cyano-3-fluorophenylboronic acid?
4-Amino-3-fluorobenzamide is a kind of organic compound. Its physical properties are quite critical, and are described as follows:
Under normal temperature and pressure, it is mostly white to white crystalline powder, which is easy to identify and operate. Its melting point is in a specific range, about 160-164 ° C. The characteristics of the melting point can help to judge the purity of the material, and it is also an important indicator of its change in heat.
In terms of solubility, 4-amino-3-fluorobenzamide shows a unique performance in organic solvents. In common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), etc., it has a certain solubility. In dichloromethane, with the specific interaction between its molecules and dichloromethane molecules, a certain degree of dissolution can be achieved, which is conducive to participating in various reactions as a reactant or intermediate in the organic synthesis reaction system. However, in water, its solubility is relatively low, because although there are polar groups such as amino groups in the molecular structure, the overall hydrophobicity is still strong, so that the force between it and water molecules is not enough to overcome its own intermolecular force and dissolve in water in large quantities.
In terms of stability, under normal conditions, 4-amino-3-fluorobenzamide has certain chemical stability. However, it should be noted that the amino group in the molecule is connected to the benzene ring, and the amino group has a certain electron-giving effect, which increases the electron cloud density of the benzene ring. When encountering specific chemical reagents such as strong oxidants, it may initiate reactions such as oxidation on the benzene ring, or chemical reactions with acids, bases, etc., changing its chemical structure and properties. And extreme environments such as high temperature and high humidity may also affect its stability, resulting in decomposition or deterioration.
What is the chemical synthesis method of 4-cyano-3-fluorophenylboronic acid?
To prepare 4-amino-3-chlorobenzoic acid, the following ancient method can be used.
First take the appropriate starting materials, preferably benzoic acid derivatives. In a suitable reactor, add an appropriate amount of halogenating reagents, such as chlorine-containing halogenating agents, under a specific temperature and reaction environment, so that the halogenation reaction occurs. This step requires fine temperature control, so that the chlorine atom is precisely replaced in a specific position of benzoic acid to obtain a chlorine-containing benzoic acid intermediate.
Then, an amino group is introduced. Nitro groups can often be introduced at specific positions on the intermediate with suitable nitrogenation reagents under appropriate conditions through a nitrogenation reaction. The conditions of the nitrogenation reaction are quite critical, which are related to the location of the nitro group introduced and the yield of the reaction. After the nitro group is successfully introduced, the reduction step is carried out. The nitro group is reduced to an amino group by a suitable reducing agent, such as a combination of metal and acid, or catalytic hydrogenation. This reduction process also requires attention to the reaction conditions to ensure that the reduction reaction proceeds smoothly and does not affect other functional groups in the molecule.
During the reaction process, the proportion of the reaction material, the reaction temperature, and the reaction time need to be precisely controlled. After each step of the reaction is completed, suitable separation and purification methods, such as crystallization, extraction, column chromatography, etc., should be used to remove impurities and improve the purity of the product. 4-Amino-3-chlorobenzoic acid can be obtained through careful operation and treatment in multiple steps. The whole process needs to be rigorous and detail-oriented according to the ancient method to make the reaction smooth and obtain the ideal product.
What are the precautions for 4-cyano-3-fluorophenylboronic acid in storage and transportation?
4-Amino-3-methoxyphenylboronic acid requires careful attention during storage and transportation.
It is active and sensitive to environmental factors. When storing, choose a dry place first. Moisture is easy to cause it to deteriorate. For example, hydrolysis occurs due to moisture absorption, causing the original structure to be damaged, causing its chemical properties to change and its efficiency to decrease. Therefore, it should be placed in a dryer or a desiccant should be added to maintain the drying environment.
Temperature is also critical. It should be stored in a low temperature environment, generally 2-8 ° C. High temperature will accelerate its decomposition or cause unnecessary chemical reactions, reducing its stability. If the storage temperature is too high, the molecular activity is enhanced, and it is easy to produce adverse changes such as polymerization.
During transportation, shock resistance is essential. This substance is mostly in the form of crystals or powders. If the packaging is not properly fixed, the transportation bumps will easily cause package damage and material leakage. And vibration or friction may cause static electricity, which poses a threat to its stability.
Packaging materials must be carefully selected. Materials that can effectively block air and moisture should be selected, such as sealed plastic bottles or aluminum foil bags. Avoid materials that easily react with 4-amino-3-methoxyphenylboronic acid to prevent interaction from affecting quality.
In addition, transportation and storage should be kept away from fire, heat and strong oxidants. This substance is flammable to a certain extent, in case of open flame, hot topic or strong oxidant, or there is a risk of combustion or explosion. Mixing or mixing with oxidants can easily trigger violent chemical reactions and endanger safety.
In summary, the storage and transportation of 4-amino-3-methoxyphenylboronic acid needs to be in a dry, low temperature environment, pay attention to shock resistance, choose the right packaging, and keep away from fire sources, heat sources and strong oxidants, so as to ensure its quality and safety.
What is the market price range of 4-cyano-3-fluorophenylboronic acid?
In today's world, the business market is numerous, and the prices of materials have their own rules. However, the price range of 4-amino-3-chlorobenzenesulfonic acid in the market is really related to all kinds of reasons, and it is difficult to generalize.
The use of this product involves the field of chemical and pharmaceutical products. In chemical industry, it is a synthetic magic agent; in medicine, it is the material required by the recipe. The price is determined, first and foremost, by supply and demand. If the market is prosperous and the supply is limited, the price will rise; if the supply exceeds the demand, the price will decline.
It is also related to the procurement of materials, and the production requires all kinds of raw materials. The price of raw materials rises and falls, and its price directly moves. If the source is smooth and the price is stable, the price of 4-amino-3-chlorobenzenesulfonic acid is also safe; if the raw material is scarce and expensive, the price of its products will also rise.
Furthermore, the fine and crude technology has a very shallow impact. Fine technology can reduce consumption and improve production, reduce its cost, and the price may be cheap; if the technology is too expensive, the price will be difficult to lower.
As for the exact price, the market is constantly changing today, and it is difficult to determine. Generally speaking, under the combination of various market conditions, the price per ton may range from several thousand yuan to tens of thousands of yuan. However, this is only an approximate estimate. The actual price should be observed in real time, and it can only be confirmed by consulting the merchants and business people. The market situation is capricious, and the fluctuation of prices changes with the situation. I hope you will observe the market situation carefully when you are looking for a purchase, so as to obtain a good price.