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What is the chemical structure of 4-Chloro-Benzenesulfonic Acid 5- (2,4-Difluoro-Phenyl) -5- [1,2,4] Triazol-1-Ylmethyl-Tetrahydro-Furan-3-Ylmethyl Ester?
This is the name of an organic compound. To clarify its chemical structure, it is necessary to analyze the various parts of this name. "4-Chloro-Benzenesulfonic Acid" means that the 4th position of benzenesulfonic acid is substituted with chlorine atoms; "5 - (2,4 - Difluoro - Phenyl) " means that the 5th position of a structure is connected with 2,4-difluorophenyl; "5 - [1,2,4] Triazol - 1 - Ylmethyl", indicating that the 5th position is also connected with 1,2,4-triazole-1-ylmethyl; "Tetrahydro-Furan-3-Ylmethyl Ester" means that it is the structure of tetrahydrofuran-3-ylmethyl ester.
In general, the structure of this compound is tetrahydrofuran-3-ylmethyl ester as the main body, with 2,4-difluorophenyl and 1,2,4-triazole-1-ylmethyl at its 5 positions at the same time, and there is a benzenesulfonic acid part, and the 4-position of benzenesulfonic acid has chlorine atom substitution. However, in order to accurately draw its chemical structure according to this name, professional chemical mapping tools and in-depth chemical knowledge are required to determine the spatial connection and relative position of each atom and group. Although the composition of each part can be roughly known, the accurate chemical structure graphic presentation is not verbally detailed, and it needs to be clearly displayed with the help of professional chemical software.
What are the main uses of 4-Chloro-Benzenesulfonic Acid 5- (2,4-Difluoro-Phenyl) -5- [1,2,4] Triazol-1-Ylmethyl-Tetrahydro-Furan-3-Ylmethyl Ester?
4-Chloro-benzenesulfonic acid 5- (2,4-difluoro-phenyl) -5- [1,2,4] triazole-1-ylmethyl-tetrahydrofuran-3-ylmethyl ester, which is an organic compound. It has a wide range of uses in the field of medicine, or can be used as a pharmaceutical intermediate. By combining with other compounds through specific chemical reactions, complex molecular structures with specific pharmacological activities can be constructed, which can help the development of new drugs and provide new possibilities for disease treatment. In the field of pesticides, it can be used as a key synthetic raw material. Through ingenious design and synthesis, pesticide products with high-efficiency control effects on pests, pathogens, etc. can be created to escort agricultural harvests and reduce the damage of pests and diseases to crops. In the field of materials science, it may also exhibit unique properties. For example, after specific treatment, it may improve some properties of materials, such as enhancing material stability, giving special optical or electrical properties, etc., so as to be applied to high-end material manufacturing and promote the development of materials science. However, its specific uses need to be carefully determined according to relevant research and practical application scenarios. With the progress of scientific research and technological innovation, its potential uses will continue to expand and deepen.
What are the physical properties of 4-Chloro-Benzenesulfonic Acid 5- (2,4-Difluoro-Phenyl) -5- [1,2,4] Triazol-1-Ylmethyl-Tetrahydro-Furan-3-Ylmethyl Ester?
4-Chloro-benzenesulfonic acid 5- (2,4-difluoro-phenyl) -5- [1,2,4] triazole-1-ylmethyl-tetrahydrofuran-3-ylmethyl ester This material has various physical properties. Its color state or crystalline body, the color is nearly pure white, and the texture is uniform, just like the purity of coagulation. At room temperature, it is stable and self-sustaining, but when it encounters a hot topic, it changes. Its melting point is about a certain temperature. At that time, the crystalline state gradually melts, like ice disappearing in warm spring. The boiling point also has a fixed number. When it reaches this degree, the state of matter changes from liquid to gas, like a cloud rising in the sky.
In terms of solubility, in organic solvents, such as alcohols and ethers, there are different behaviors. It dissolves in alcohols, like fish getting water, and dissolves infinitely with each other, forming a uniform phase; it can also dissolve a little in ether, but it is not completely fused. It is slightly layered, with supernatant in the upper layer, and undissolved micromatter in the lower layer.
The value of density is slightly heavier than that of water. It is thrown into water, such as a stone sinking into the abyss and sinking to the bottom of the water. The refractive index also has a specific number. Light shines on it and is refracted at a specific angle. If light encounters glaze, it presents a wonderful light path
These physical properties are all inherent in them and play a crucial role in chemical research, industrial preparation, pharmaceutical synthesis, and many other fields, just as the cornerstone is indispensable for a high-rise building.
4-Chloro-Benzenesulfonic Acid 5- (2,4-Difluoro-Phenyl) -5- [1,2,4] Triazol-1-Ylmethyl-Tetrahydro-Furan-3-Ylmethyl Ester?
The synthesis of 4-chloro-benzenesulfonic acid-5- (2,4-difluoro-phenyl) -5- [1,2,4] triazole-1-ylmethyl-tetrahydrofuran-3-ylmethyl esters is a key exploration in the field of organic synthetic chemistry.
To synthesize this substance, it is first initiated by esterification reaction. 4-Chloro-benzenesulfonic acid can be taken first and mixed with 5- (2,4-difluoro-phenyl) -5- [1,2,4] triazole-1-ylmethyl-tetrahydrofuran-3-alcohol compounds containing appropriate protective groups. In this process, it is necessary to carefully select suitable catalysts, such as concentrated sulfuric acid or p-toluenesulfonic acid, which can effectively promote the esterification reaction and accelerate the formation of ester bonds.
Furthermore, the choice of solvent for the reaction is also crucial. It is advisable to choose inert organic solvents such as dichloromethane and chloroform, which not only dissolve the reactants well, but also contribute greatly to the stability of the reaction system, which can avoid unnecessary side reactions.
Temperature control is also a key factor in the success or failure of the synthesis. Generally speaking, the initial reaction can be carried out at a lower temperature, about 20-30 ° C, to promote the full mixing and interaction of the reactants. Subsequently, it can be gradually heated to 50-70 ° C to accelerate the reaction process and make the esterification reaction more complete.
After the reaction is completed, the separation and purification of the product cannot be ignored. Column chromatography can be used to select suitable silica gel as the stationary phase, and mixed solutions of n-hexane and ethyl acetate in different proportions can be used as the mobile phase to achieve effective separation of products and impurities, and finally obtain high-purity 4-chloro-benzenesulfonic acid-5- (2,4-difluoro-phenyl) -5- [1,2,4] triazole-1-methyl-tetrahydrofuran-3-ylmethyl ester.
4-Chloro-Benzenesulfonic Acid 5- (2,4-Difluoro-Phenyl) -5- [1,2,4] Triazol-1-Ylmethyl-Tetrahydro-Furan-3-Ylmethyl Ester What are the precautions during use?
4-Chloro-benzenesulfonic acid 5- (2,4-difluoro-phenyl) -5- [1,2,4] triazole-1-ylmethyl-tetrahydrofuran-3-ylmethyl ester, this is a rather complex chemical substance. During use, many matters need to be paid attention to.
Bear the brunt of it, and safety protection should not be underestimated. Due to its chemical properties or certain hazards, be sure to wear complete protective equipment when exposed. Such as protective gloves, which can effectively avoid direct contact with the skin to prevent chemical substances from eroding the skin, causing adverse consequences such as allergies and burns; protective glasses are also indispensable to prevent them from splashing into the eyes and causing serious damage to the eyes. If it is operated in the laboratory, wearing laboratory clothes can reduce the risk of clothing contamination.
Furthermore, precise operation procedures must be strictly followed. Whether it is weighing, dissolving, or reaction steps, it must be carried out in accordance with established specifications. When weighing, the accuracy of the instruments used needs to be adapted, and the dosage should be accurate. Due to dosage deviation or deviation of reaction results, or even accidents. During the dissolution process, the selected solvent and dissolution conditions are also extremely critical, and improper selection or incomplete dissolution will affect subsequent reactions.
Storage conditions should also not be ignored. It needs to be stored in a suitable environment according to its characteristics. If it is sensitive to temperature, too high or too low temperature may cause it to deteriorate, so it needs to be stored under temperature control. If it is prone to moisture, a dry environment is necessary to avoid moisture affecting its chemical properties.
In addition, ventilation conditions in the place of use are also crucial. Good ventilation can discharge volatile chemicals in time, reduce the concentration of harmful substances in the air, avoid the operator from inhaling too much harmful gases, and protect health. And during the operation, it is also necessary to closely observe the reaction phenomenon in order to detect abnormalities in time and take corresponding measures.