4-Chloro-3,5-Difluorobromobenzene

Hongda Chemical

Specifications

HS Code	998420
Chemical Formula	C6H2BrClF2
Molecular Weight	239.43
Appearance	Colorless to light yellow liquid
Boiling Point	190 - 192 °C
Density	1.805 g/cm³
Solubility	Insoluble in water, soluble in organic solvents
Flash Point	75.8 °C
Refractive Index	1.523
Stability	Stable under normal conditions

As an accredited 4-Chloro-3,5-Difluorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100 - gram vial of 4 - chloro - 3,5 - difluorobromobenzene, well - sealed for safety.
Storage	4 - chloro - 3,5 - difluorobromobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to prevent potential reactions.
Shipping	4 - chloro - 3,5 - difluorobromobenzene is shipped in sealed, corrosion - resistant containers. Packaging adheres to strict chemical transport regulations. Shipment is via approved carriers ensuring safety during transit.

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General Information

Historical Development

4-Chloro-3,5-difluorobromobenzene is also an organic compound. At the beginning, the researchers devoted themselves to exploring the properties and preparation of the compound. At the beginning, the method of preparation was simple and ineffective, the yield was quite low, and the quality was not pure.
As the years passed, the researchers thought hard and the technique was gradual. In terms of reaction conditions, such as temperature, pressure, and catalytic agents, they were all carefully studied. After years of research, the new method was developed, the yield was greatly increased, and the quality was also pure.
The history of this compound is really the process of unremitting progress by the researchers. From the beginning of the difficulty, to the achievement, all rely on the perseverance of the researchers, with wisdom and diligence, to break through all kinds of difficulties, so that their skills are improving, and this compound has gradually become the most important in the industry.

Product Overview

4-Chloro-3,5-difluorobromobenzene is also an organic compound. Its shape is colorless to light yellow liquid with a special odor. This compound is widely used in the field of organic synthesis. It can be used as a key intermediate in the synthesis of medicine, pesticides, electronic chemicals, etc.
The preparation method is often obtained by halogenation of specific aromatic hydrocarbons as the starting material. During the reaction, strict control conditions, such as temperature, reactant ratio, catalyst type and dosage, are required to ensure the purity and yield of the product.
The chemical properties of 4-chloro-3,5-difluorobromobenzene are active and show unique properties in many chemical reactions. Although it is toxic and corrosive, strict safety procedures must be followed during operation to ensure the safety of the experimenter and the environment.

Physical & Chemical Properties

4-Chloro-3,5-difluorobromobenzene is also an organic compound. Its physical and chemical properties can be explored. Looking at its physical properties, at room temperature, it is mostly liquid, colored or transparent, with a special smell. Its boiling point and melting point are inherent characteristics. The boiling point is related to the temperature of gasification, and the melting point is the degree of solid-to-liquid conversion. And the density is also a characteristic, related to its fluctuation in the medium.
As for the chemical properties, it is active because it contains halogen atoms. Chlorine, fluorine, and bromine atoms can all initiate many reactions. Such as the reaction of nucleophilic substitution, halogen atoms can be replaced by nucleophilic reagents. This compound has a wide range of uses in the field of organic synthesis, or is a key intermediate, which can participate in the construction of various complex organic molecules. Its physical and chemical properties are the key to opening the door to the wonders of organic synthesis.

Technical Specifications & Labeling

4-Chloro-3,5-difluorobromobenzene is also a chemical substance. Its process specifications and identification (product parameters) are related to manufacturing and identification.
To make this substance, strict methods must be followed. In the reaction kettle, make the reactants according to the appropriate proportion, temperature and duration. The raw materials should be pure and the equipment should be clean to prevent impurities from disturbing it.
In terms of identification, its name 4-chloro-3,5-difluorobromobenzene is clear and clear. On the packaging, the chemical formula, molecular weight, purity and other parameters should be marked so that people can know its properties. Warning labels are also required. If the material is toxic, rotten, etc., it can avoid danger. In this way, the process specifications and labels are clear to ensure that the production and use of 4-chloro-3,5-difluorobromobenzene are safe and accurate.

Preparation Method

4-Chloro-3,5-difluorobromobenzene is a key intermediate in organic synthesis and has a wide range of uses in the fields of medicine and pesticides. The method of its preparation, raw materials and production process are of paramount importance.
Commonly used raw materials include halogenated benzene, etc. It is prepared by multiple delicate reactions. Initially, based on specific halogenated benzene, in a suitable solvent, mixed with fluoride in a specific ratio, assisted by a specific catalyst, temperature control in a certain range, triggering a nucleophilic substitution reaction. This step requires precise control of the reaction conditions, such as a slight temperature deviation, the purity of the product may be affected.
After the reaction is completed, the product is purified through extraction, distillation and other steps. The subsequent bromination reaction is carried out, and a suitable brominating agent is selected. Under a specific reaction environment, the bromine atom precisely replaces the hydrogen atom at the target position. The regulation of the reaction activity in this step is difficult, and it is related to the correctness of the structure of the final product.
During the whole preparation process, it is crucial to build an efficient catalytic mechanism. The selection of highly active and highly selective catalysts can improve the reaction rate and yield. At the same time, strict monitoring of each reaction step and fine regulation of the reaction parameters can stabilize the preparation of high-purity 4-chloro-3,5-difluorobromobenzene to meet the needs of the industry.

Chemical Reactions & Modifications

Today there is a substance called 4 - Chloro - 3,5 - Difluorobromobenzene. In the field of chemistry, its reaction and modification are crucial.
To understand its reaction, its structure must be carefully investigated. In this compound, chlorine, fluorine and bromine atoms have their own characteristics, which affect their reaction paths. Chlorine atoms have considerable activity and can lead to nucleophilic substitution reactions. Fluorine atoms have strong electronegativity, which causes changes in the electron cloud density of the benzene ring, which in turn affects the reaction activity and selectivity.
When talking about modification, chemical means can be used to change its structure and obtain new properties. If a specific group is introduced, its solubility and stability can be changed. Functional groups can be added at specific positions in the benzene ring to achieve specific chemical purposes.
The reaction and modification of this compound are really the key to chemical research, and they can be deeply studied in the future, and more beneficial results can be obtained, which will contribute to the development of chemistry.

Synonyms & Product Names

4-Chloro-3,5-difluorobromobenzene is also a genus of chemical substances. Although its name is different from the common saying, it is important in the industry. There are also many aliases for this thing. In the field of chemical industry, it is often the main angle of various reactions due to its unique characteristics.
Looking at its naming, "4-chloro-3,5-difluorobromobenzene", according to the rules of chemical nomenclature, its molecular structure is accurately identified. The atomic positions of chlorine, fluorine and bromine are distinct, and the benzene ring is the base, the structure is established, and the properties are derived therefrom.
As for the trade name, it varies according to different manufacturers and uses. However, it is important to highlight its characteristics and uses. It is either related to its high purity, or related to its excellent reactivity. This is all a consideration for chemical practitioners to choose and use.
In today's world, chemical industry has been progressing, and 4-chloro-3,5-difluorobromobenzene has been used in medicine, materials and other industries, all of which have developed their strengths, helping the industry to thrive and become an industry.

Safety & Operational Standards

Safety and Handling Specifications for 4-Chloro-3,5-Difluorobromobenzene
4-Chloro-3,5-difluorobromobenzene is an important compound in chemical research. During experimental operation, safety regulations are crucial.
This compound has certain chemical activity, which is related to personal safety and experimental results. When storing, be sure to keep it in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent it from changing due to environmental factors and causing safety risks.
When using and operating, the experimenter should be in front of appropriate protective equipment, such as protective gloves, goggles, etc. Gloves must be able to resist the erosion of the compound, and goggles can protect the eyes from accidental splashing. During the weighing process, the action should be stable and accurate to avoid the escape of its powder or liquid.
During the reaction operation, strictly control the reaction conditions, such as temperature, pressure, reaction time, etc. According to the established reaction process, and must not be changed without authorization. If the reaction needs to be heated, choose an appropriate heating method, and pay close attention to temperature changes to prevent the reaction from getting out of control due to excessive temperature.
After the experiment is completed, the remaining 4-chloro-3,5-difluorobromobenzene and related waste should be properly disposed of according to regulations. Do not discard at will to avoid polluting the environment or causing subsequent safety problems.
In short, in the whole process of research and use of 4-chloro-3,5-difluorobromobenzene, strict adherence to safety and operating standards can ensure the smooth operation of the experiment, and ensure the safety of personnel and the environment.

Application Area

Today, there is a compound called 4-chloro-3,5-difluorobromobenzene. This compound has many application fields and is extraordinary.
In the field of medicinal chemistry, it can be used as a key intermediate to help create new specific drugs. Due to its unique molecular structure and precise fit with specific targets in the body, it is expected to develop a medicine with excellent efficacy and small side effects.
In the field of materials science, with its special chemical properties, it can be used to synthesize functional materials with special optical and electrical properties. After clever design and reaction, materials suitable for high-end electronic equipment and optical instruments can be prepared to improve product performance and quality.
In the field of agricultural chemistry, high-efficiency and low-toxicity pesticides can be prepared through derivatization reactions. By precisely acting on the specific physiological processes of pests, it can effectively prevent and control pests and diseases, and has a slight impact on the environment, contributing to the sustainable development of agriculture.

Research & Development

Today, there is a substance named 4-chloro-3,5-difluorobromobenzene. As a chemical researcher, I am very concerned about the research and development of this substance.
This substance has unique properties. Its structure contains the coexistence of chlorine, fluorine and bromine atoms, giving it different chemical activities. In the investigation of the reaction mechanism, I have carefully studied and observed its changes under different conditions. Or when it encounters nucleophiles, I see the breaking and recombination of its bonds, which is like a delicate dance in the microscopic world.
In terms of development and application, after repeated experiments, it has been found that it has great potential in the synthesis of new materials. It can be used as a key intermediate to build a unique molecular structure and contribute to the improvement of material properties. I often think that with time and in-depth exploration, it will be able to emerge in more fields, inject new vitality into the development of chemistry, promote the progress of science and technology, and bring benefits to human life.

Toxicity Research

We are dedicated to the toxicity study of 4-chloro-3,5-difluorobromobenzene. This compound is widely used in industrial and scientific research fields, but its toxic effects are unknown, so we investigated it.
Initially, animals were used as samples to observe their reactions after exposure to this compound. Observe its physiological characteristics, behavioral changes and differences in organs. Over time, it was found that the tested animals showed signs of fatigue, poor diet, and even signs of organ lesions.
Reanalyze its toxicological mechanism, explore the metabolic pathway of the compound after entering the body, and its effects on the cellular and molecular levels. Find its interaction with biomacromolecules to clarify the root cause of toxicity.
Studies have shown that 4-chloro-3,5-difluorobromobenzene has certain toxicity and can cause physiological dysfunction in animals. This study provides a basis for the safe use and protection of this compound. It is hoped that future generations will be cautious when applying it to avoid potential harm.

Future Prospects

Fu 4 - Chloro - 3,5 - Difluorobromobenzene, it is also a matter of transformation. Its future prospects can be looked forward to. This compound may have a big impact on the way of research and development. It can be used as a first-generation compound, which can be skillfully modified, or can become a good effect, and solve the suffering of many diseases.
In the field of material science, it is also promising. Or it can be synthesized into special materials, so that the material has extraordinary properties, such as better performance and quality.
In addition, in the field of synthesis, it is important. It can take advantage of various reactions to derive a variety of compounds and expand the way of synthesis. In addition, 4 - Chloro - 3,5 - Difluorobromobenzene has not yet been developed, and it is full of opportunities. We will wait for the researchers to explore diligently in order to reveal their capabilities and benefit the world.

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Frequently Asked Questions

As a leading 4-Chloro-3,5-Difluorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

4-Chloro-3, what are the chemical properties of 5-Difluorobromobenzene

4-Chloro-3,5-difluorobromobenzene is one of the organic compounds. It has the characteristics of halogenated aromatic hydrocarbons and is formed by connecting three halogen atoms of bromine, chlorine and fluorine to the benzene ring.
This compound is chemically active, due to the strong electronegativity of halogen atoms, which causes the electron cloud density of the benzene ring to change. The existence of bromine atoms, chlorine atoms and fluorine atoms makes the molecular polarity unique and affects its physical and chemical behavior.
In terms of nucleophilic substitution reactions, halogen atoms can be replaced by nucleophilic reagents. Due to the high carbon-fluorine bond energy of fluorine atoms, it is difficult to leave; while the carbon-bromine bond of bromine atoms is relatively weak, and under suitable conditions, it is easy to be For example, when encountering hydroxyl negative ions (OH~), bromine atoms may be replaced by hydroxyl groups under specific solvents and temperatures to form corresponding phenolic derivatives.
It can also participate in metal-catalyzed coupling reactions. Under the action of metal catalysts such as palladium and nickel, it can be coupled with carbon-containing nucleophiles to form carbon-carbon bonds. This is commonly used in the organic synthesis of complex compounds, which can grow carbon chains and introduce diverse functional groups.
In addition, due to the electron-absorbing effect of halogen atoms, the electron cloud density of the benzene ring decreases, which decreases the activity of the electrophilic substitution reaction of the benzene ring. When reacting with electrophilic reagents, the reaction conditions are more harsh than benzene, and the substitution position is also restricted by the localization effect of halogen atoms.
In the field of organic synthesis, 4-chloro-3,5-difluorobromobenzene has unique chemical properties and is an important intermediate. It can be used to prepare various organic compounds such as drugs, pesticides, and materials through a series of reactions.

What are the main uses of 4-Chloro-3, 5-Difluorobromobenzene

4-Chloro-3,5-difluorobromobenzene is a crucial intermediate in organic synthesis and has a wide range of indispensable uses in the fields of medicine, pesticides and materials science.
In the field of medicine, it is often the key starting material for the synthesis of new drugs. By ingeniously modifying and transforming it, molecular structures with unique physiological activities can be constructed. For example, in the creation of many anti-infective drugs, 4-chloro-3,5-difluorobromobenzene plays the role of the starting cornerstone. After multiple steps of delicate synthesis, the final drug has the ability to precisely act on pathogens, and has little effect on normal human cells. It is a key factor in improving the efficacy and safety of drugs.
In terms of pesticides, this compound is also an important intermediate for the synthesis of highly efficient and low-toxicity pesticides. With its special chemical structure, the synthetic pesticide can precisely act on harmful organisms, such as insects, fungi, etc., effectively inhibit their growth and reproduction, and minimize the adverse effects on the environment and non-target organisms, providing a solid boost for the sustainable development of agriculture.
In the field of materials science, 4-chloro-3,5-difluorobromobenzene can be used to prepare organic functional materials with excellent performance. After a specific chemical reaction, it can be introduced into polymer, thereby significantly improving the electrical and optical properties of the material. For example, in the development of organic Light Emitting Diode (OLED) materials, it can optimize the luminous efficiency and stability of the material, so that the image quality of the display device is clearer and the color is more brilliant.
In conclusion, 4-chloro-3,5-difluorobromobenzene, with its unique chemical properties, plays an irreplaceable role in many key fields, promoting the continuous progress and innovation of related industries.

What is the synthesis method of 4-Chloro-3, 5-Difluorobromobenzene

The synthesis method of 4-chloro-3,5-difluorobromobenzene is quite exquisite. The ancient alchemists have studied a lot of gold and petrochemical science. Although the equipment used is very different from today's, the spirit of exploration can be used for today's synthesis.
To make this compound, one method is to start with a suitable halogenated aromatic hydrocarbon. First take a halogen containing a benzene ring. This halogen needs to have a substitutable group, such as chlorine and bromine. Based on it, fluorine atoms are introduced by means of nucleophilic substitution. A suitable fluorine source, such as potassium fluoride, can be used in a specific solvent to catalyze, so that fluorine atoms gradually replace groups at specific positions on the benzene ring. In this regard, the choice of solvent is crucial, and its solubility to the reactants and products needs to be considered, and it cannot react adversely with the reactants or products.
After the fluorine atom is successfully introduced, a halogenated benzene derivative containing fluorine is obtained. Then, for the chlorine atom at the target position, a substitution reaction can be performed. This step can utilize the wonders of metal-organic reagents, such as organolithium reagents or Grignard reagents. First, the metal-organic reagent interacts with the halogenated aromatic hydrocarbon to form an active intermediate, and then reacts with a suitable halogenating agent to replace the chlorine atom at the target position with a bromine atom, resulting in 4-chloro-3,5-difluorobromobenzene.
During the reaction process, the control of temperature and time should not be ignored. The temperature is related to the reaction rate and product selectivity; the length of time affects the degree of reaction. Careful inspection and repeated trials are required to obtain the ideal yield and purity. And after each step of the reaction, the method of separation and purification must be used to remove its impurities and ensure the purity of the product. In this way, the synthesis of this compound can be achieved.

4-Chloro-3, 5-Difluorobromobenzene what to pay attention to when storing and transporting

4-Chloro-3,5-difluorobromobenzene is also an organic compound. During its storage and transportation, many matters must not be ignored.
First words storage. This compound should be stored in a cool, dry and well-ventilated place. Because of high temperature and humidity, it may cause chemical reactions and cause it to deteriorate. For example, high temperature can make its volatilization intensify, or react with substances such as water vapor in the environment, damaging its purity. And it needs to be kept away from fires and heat sources, because it is flammable, in case of open flames and hot topics, there is a risk of explosion. It should be stored separately from oxidants, acids, alkalis, etc., and cannot be mixed. Due to its active chemical properties, contact with the above substances is prone to violent reactions and accidents. And the storage area should be equipped with suitable materials to contain the leakage, in case of leakage, it can be disposed of in time to prevent its spread and endanger the environment.
As for transportation, caution is also required. Before transportation, be sure to ensure that the packaging is complete and sealed. Poor packaging can easily cause leakage, pollute the environment, and endanger the safety of transportation personnel. During transportation, it should be protected from sun exposure, rain exposure, and high temperature. Vehicles should be equipped with corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment. If a leak occurs during transportation, it can be dealt with in time. Drivers and escorts need to be familiar with the properties, hazards and emergency treatment methods of this compound. When transporting, they must strictly follow the specified route and do not stop in densely populated areas and residential areas.
In this way, when storing and transporting 4-chloro-3,5-difluorobromobenzene, pay attention to the above matters to ensure safety and avoid disasters.

What are the effects of 4-Chloro-3, 5-Difluorobromobenzene on the environment and human health?

4-Chloro-3,5-difluorobromobenzene is one of the organic compounds. It has a wide range of industrial uses, such as pharmaceuticals, pesticides, and material synthesis. It is an important raw material. However, this substance may be harmful to the environment and human health.
View its impact on the environment. This substance has certain toxicity. If it is accidentally released into the environment, it can cause soil and water pollution. Because of its stable chemical properties, it is difficult to degrade in the environment, or it can be retained for a long time. It is tired of the ecosystem and disturbs the balance of the biological chain. For example, it enters rivers, lakes and seas, or is ingested by aquatic organisms, causing abnormal growth, reproduction, or even death, endangering aquatic biodiversity.
As for the impact on human health. This substance can enter the human body through respiratory tract, skin contact, accidental ingestion, etc. In the human body, or damage the nervous system, respiratory system, liver, kidney and other organs. If inhaled in high concentrations, it can cause respiratory symptoms such as cough, asthma, breathing difficulties; long-term exposure, or damage the nervous system, causing headache, dizziness, fatigue, memory loss, etc.; those who eat by mistake, or harm the digestive system, causing nausea, vomiting, abdominal pain, diarrhea, etc., serious cases can be life-threatening.
Therefore, when producing and using 4-chloro-3,5-difluorobromobenzene, strict safety operating procedures should be followed and effective protective measures should be taken to avoid its harm to the environment and human health. It is also necessary to increase environmental monitoring and governance to ensure ecological environment and personal safety.