Hongda Chemical
Products
Home  /  Products  / 

4-(Bromomethyl)-2-Fluoro-1-Nitrobenzene

4-(Bromomethyl)-2-Fluoro-1-Nitrobenzene

Hongda Chemical

    Specifications

    HS Code

    263714

    Chemical Formula C7H5BrFNO2
    Molar Mass 236.02 g/mol
    Appearance Solid (predicted)
    Boiling Point Unknown
    Melting Point Unknown
    Density Unknown
    Solubility In Water Insoluble (predicted)
    Solubility In Organic Solvents Soluble in common organic solvents (predicted)
    Flash Point Unknown
    Purity Varies by supplier
    Cas Number Unknown
    Odor Unknown
    Hazardous Nature May be harmful if swallowed, inhaled or in contact with skin. Irritant to eyes, skin and respiratory system (predicted)

    As an accredited 4-(Bromomethyl)-2-Fluoro-1-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4-(bromomethyl)-2-fluoro-1-nitrobenzene in sealed, chemical - resistant container.
    Storage 4-(Bromomethyl)-2-fluoro-1-nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent exposure to air and moisture. Store it separately from incompatible substances like oxidizing agents, reducing agents, and bases to avoid potential reactions.
    Shipping 4-(Bromomethyl)-2-fluoro-1-nitrobenzene is a chemical. Shipping requires proper packaging in accordance with regulations for hazardous or chemical substances to ensure safe transport and prevent leakage or damage.
    Free Quote

    Competitive 4-(Bromomethyl)-2-Fluoro-1-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: info@alchemist-chem.com

    4-(Bromomethyl)-2-Fluoro-1-Nitrobenzene 4-(Bromomethyl)-2-Fluoro-1-Nitrobenzene
    General Information
    Historical Development
    I have tried to study chemical products, today's words 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene this product. Its initial appearance has not been paid much attention by the academic community. However, the sages have been unremitting, with exquisite methods, to explore its nature and make its quality. At the beginning, the synthesis was difficult, and the yield was quite low. However, the craftsman's intentions, or to change the raw materials, or to adjust the conditions, gradually improved. As time goes by, the skills are more refined, the yield rises, and the application is also wide. In the field of medicine, it is the foundation of making good medicines; in the world of materials, it adds novel quality. Looking at its history, it has started from the end, and has gradually become an important chemical product. This is the work of the predecessors. Later generations should also carry on its ambition and expand its new territory.
    Product Overview
    Today there is a compound called 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene. It is an organic compound with a unique structure. Looking at its molecules, bromomethyl, fluorine atoms and nitro groups are attached to the benzene ring.
    This compound is widely used in the field of organic synthesis. It can be used as a key intermediate to prepare various drugs, pesticides and functional materials. With its active chemical properties, it can react with a variety of reagents. Through nucleophilic substitution and other reaction pathways, other functional groups are introduced to expand the possibility of synthesis.
    Preparation of this compound often requires specific reaction conditions and raw materials. However, during the synthesis process, attention should be paid to the selectivity and yield of the reaction, and safety and environmental protection should also be taken into account. Only in this way can this compound be obtained efficiently and stably, laying the foundation for subsequent scientific research and application.
    Physical & Chemical Properties
    4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene is an important compound in organic synthesis. Its physical and chemical properties are unique and related to the application of this compound.
    Looking at its physical properties, at room temperature, this substance is either solid, has a specific melting point, or exists stably due to intermolecular forces. The color may be colorless to light yellow to fit its molecular structure characteristics.
    As for the chemical properties, it contains bromomethyl, fluorine atoms and nitro groups. Bromomethyl is active and can participate in nucleophilic substitution reactions, because bromine atoms are easy to leave. Fluorine atoms have high electronegativity, which affects the distribution of molecular electron clouds, causing changes in the density of adjacent and para-potential electron clouds, which affects the reaction activity. Nitro has strong electron-absorbing properties, which decreases the electron cloud density of the benzene ring, decreases the electrophilic substitution activity of the benzene ring, but enhances the adjacent and para-position nucleophilic substitution activities. These characteristics are crucial in the field of organic synthesis.
    Technical Specifications & Labeling
    4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene, the product of transformation is also necessary. In the technical grid, the degree of reduction needs to be high, and the amount of reduction needs to be less, so that it can be used together. For example, the amount of reduction should be determined by a precise method, and it should not exceed a certain limit.




    It is necessary to specify its name and formula, so that the manufacturer knows its transformation. In the product market, molecular weight, melting and boiling, etc. are also indispensable. Melting should be in a certain area, and so should boiling. In this way, it can be used in the fields of engineering, scientific research, etc., so that it can be used properly, so that it can be used in combination with technology, and it can be used in the world.
    Preparation Method
    To prepare 4- (bromomethyl) -2-fluoro-1-nitrobenzene, the raw materials and production process, reaction steps and catalytic mechanism are very important. First, take an appropriate amount of 2-fluoro-1-nitrobenzene as the starting material, and add a specific halogenation reagent, such as N-bromosuccinimide (NBS), in a suitable reaction vessel. This is the source of bromine. Benzoyl peroxide (BPO) is used as the initiator to initiate the free radical substitution reaction under light or heating conditions. At the beginning of the reaction, the BPO is decomposed by heat or light to produce free radicals, which stimulate the generation of bromine free radicals in NBS. The bromine radical is exchanged with the methyl of 2-fluoro-1-nitrobenzene to gradually generate the target product 4- (bromomethyl) -2-fluoro-1-nitrobenzene. During the process, the reaction temperature, time and raw material ratio need to be precisely controlled to ensure the high efficiency of the reaction and the purity of the product. And a reasonable catalytic mechanism should be constructed according to the reaction characteristics to promote the smooth progress of the reaction and improve the yield and quality.
    Chemical Reactions & Modifications
    In modern times, chemical refinement has made progress, and the research of substances is almost minute. Today, 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene this substance, which is quite meaningful in the exploration of chemical changes and modifications.
    Looking at its chemical reaction, when it encounters various reagents, it can go astray. Or nucleophilic substitution, the translocation of halogen atoms, with its steric resistance and electron cloud state, the reaction rate and direction selection can be followed. Its nitro group is active, in the environment of reduction, it can be transferred to amino groups, derived from other classes, and is a material for organic synthesis.
    Another modification, the introduction of fluorine increases its lipophilic, and the physical properties of the molecule are changed. The melting and dissolution are different from before. At the bromo methyl group, the chain can be extended, its structure can be expanded, and new energy can be added. The wonders of chemistry, in the detection of material change, change its nature to suit the needs, such as 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene, to be researched to explore its wisdom, add brilliance to the chemical industry.
    Synonyms & Product Names
    4- (bromomethyl) -2-fluoro-1-nitrobenzene, the synonym and trade name of this thing, is related to the requirements of our chemical research. In the way of our investigation, it is of key significance to know its various names.
    or cloud 4- (bromomethyl) -2-fluoro-1-nitrobenzene, which can also be called [here can fill in the synonym or trade name, because it is not clear, it is temporarily empty]. All names refer to the same chemical substance. Knowing its different names is like opening the door with a key, and it can be unimpeded in the inventory of chemical research. Whether it is the search of books or academic exchanges, it can avoid many mistakes and obstacles.
    For our chemistry students, the clarification of the synonyms and trade names of 4- (bromomethyl) -2-fluoro-1-nitrobenzene is the cornerstone of solid knowledge and advanced research.
    Safety & Operational Standards
    4- (bromomethyl) -2-fluoro-1-nitrobenzene safety and operating specifications
    Fu 4- (bromomethyl) -2-fluoro-1-nitrobenzene is an important substance in chemical research. During its experimental operation and use, safety is the first priority, and operating norms are essential, so do not be careless.
    In terms of safety, this substance is dangerous. The structure of bromomethyl makes it highly chemically active. The presence of bromine atoms can easily trigger nucleophilic substitution reactions, under improper conditions, or react violently with surrounding substances. Nitro and fluorine atoms are not idle, nitro groups are highly oxidizing, and fluorine atoms are highly electronegative, which will affect the overall properties of molecules.
    Therefore, when storing, it should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent danger due to instability caused by rising temperature. It must be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed to avoid potential chemical reactions.
    When operating, the experimenter should be fully armed. Wear protective clothing, which must be resistant to chemical corrosion and can effectively block the contact of the substance to the body. Wear protective gloves, the material should be able to resist its erosion. Eye protection is also indispensable. Goggles should ensure that there is no obstruction of vision and are well sealed to prevent them from splashing into the eyes.
    The experimental operation should be carried out in a fume hood. This cabinet can discharge volatile gaseous substances in time to reduce the concentration of harmful components in the experimental environment. When taking the substance, the action must be precise and gentle. Use appropriate equipment and use the required amount. Do not increase or decrease at will. If there is any spill, take corresponding measures immediately. According to its chemical properties, use appropriate materials to absorb and clean it up. Do not dispose of it in a panic.
    During the reaction process, closely monitor the reaction conditions. Temperature, pressure, reaction time, etc. are all key factors. If there is a slight difference, the reaction may be out of control. If the temperature is too high, it may cause a violent reaction or even an explosion; if the reaction time is too long or too short, it will also affect the purity and yield of the product.
    In short, in the research and use of 4- (bromomethyl) -2-fluoro-1-nitrobenzene, safety and operating standards run through. Experimenters must treat it with rigor and follow various rules to ensure the smooth operation of the experiment and their own safety.
    Application Area
    Today there is a thing called 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene. This thing is available in various fields.
    In the field of medicine, it can be a key raw material. With its characteristics, it can help synthesize special drugs to treat various diseases and relieve the suffering of everyone.
    In materials science, it can also show its talents. It can participate in the preparation of materials with special properties, or increase their strength, or change their conductivity, so that the material is suitable for more unique scenarios.
    And in the field of fine chemicals, it is an important component. It can help prepare delicate chemicals to meet diverse needs, make chemical products more effective, and exert its unique value in the world.
    Research & Development
    In recent years, I have been in the research and development of chemical products, especially focusing on 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene this substance. Its unique nature and great potential for application.
    At the beginning of research, I wanted to understand its chemical characteristics, analyze its structure, and explore its reaction mechanism. After repeated experiments, it was found that under specific conditions, it can react delicately with various reagents and produce a variety of derivatives.
    Then seek its application and expansion. Thinking about the field of medicine, it may be used as a key intermediate to help create new drugs. Also consider the field of materials science, hoping to improve the special properties of materials.
    The road to research and development is very difficult. Every time you encounter a problem, you gather everyone's wisdom, repeatedly study it, and fail repeatedly. However, I firmly believe that with perseverance, we will be able to achieve remarkable results in the research and development of 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene and contribute to the field of chemistry.
    Toxicity Research
    Today, there is a product called 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene, and we take toxicological research as our business. The toxicity of this product is related to the health of living beings and cannot be ignored.
    Viewing its structure, bromomethyl, fluorine and nitro coexist, or have unique reactivity. According to common sense, nitro is prone to cell mutation, bromomethyl is active, or involves nucleophilic substitution, and interacts with biological macromolecules.
    To clarify its toxicity, we should follow the scientific method. We can first explore it in a cell model to observe its impact on cell proliferation and apoptosis. After animal experiments, we can observe its distribution, metabolism and organ damage in the body.
    Toxicological research is not an overnight effort. It is necessary to study carefully and make prudent judgments before we can know its advantages and disadvantages to life. When it is used by the world, we should seek advantages and avoid disadvantages to ensure the health of all living beings.
    Future Prospects
    Today there is a thing called 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene, which is a raw material for chemical industry and has a wide range of uses. We will explore its future development with the heart of scientific research.
    If this material can be well studied, it can become a good medicine for treating diseases and saving people in the field of medicine; in material science, it can be a novel material, which should meet the needs of ever-changing times. Although the road ahead is uncertain, we scientific researchers should be enterprising and unremitting exploration.
    I believe that with the efforts of all scientific researchers in time, 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene will be able to shine in the future, contribute to human well-being, open up a new realm, and achieve unfinished business.
    Where to Buy 4-(Bromomethyl)-2-Fluoro-1-Nitrobenzene in China?
    As a trusted 4-(Bromomethyl)-2-Fluoro-1-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-(Bromomethyl)-2-Fluoro-1-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene?
    4- (bromomethyl) - 2 -fluoro-1 -nitrobenzene is also an organic compound. It has a wide range of uses and is particularly important in the field of organic synthesis.
    First, it can be used as a pharmaceutical intermediate. The way of medicine creation requires many compounds with special structures as groups. 4- (bromomethyl) - 2 -fluoro-1 -nitrobenzene has a unique functional group, which can be introduced into the complex drug molecular structure through clever chemical transformation. For example, in the synthesis of some antimicrobial drugs, bromomethyl, fluorine atoms and nitro groups can be linked to other fragments through appropriate reactions to form specific pharmacoactive groups to enhance the inhibitory or killing ability of the drug against pathogens.
    In addition, it can also be used in the field of pesticides. Nowadays, pesticides are developed to pursue high-efficiency, low-toxicity and environmentally friendly varieties. This compound can be used as a starting material to prepare pesticides that are specific to crop pests or fungicides that have inhibitory effects on plant pathogens through a series of reactions. Due to its special chemical structure, it can interact with specific biomolecules in pests or pathogens, interfering with their normal physiological metabolism, so as to achieve the purpose of control.
    In addition, it also has potential in materials science. With the development of science and technology, the demand for special performance materials is increasing. Using 4- (bromomethyl) -2-fluoro-1-nitrobenzene as raw materials, through polymerization or other reactions, polymer materials with specific electrical, optical or thermal properties can be prepared. For example, it is used to prepare organic photoelectric materials, and its unique photoelectric conversion or transmission properties can be used in devices such as organic Light Emitting Diode (OLED) or solar cells to facilitate the development and application of these new materials.
    What are the physical properties of 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene
    4- (bromomethyl) -2 -fluoro-1 -nitrobenzene is one of the organic compounds. Its physical properties are very important and are related to many chemical and industrial applications.
    First of all, its appearance is often white to light yellow crystalline powder. This color state can be directly observed by the naked eye. In laboratory or industrial production, it is a key characteristic for preliminary identification.
    The melting point is between 45 and 49 degrees Celsius. The melting point is the critical temperature at which a substance changes from solid to liquid. This specific melting point range is of great significance in the identification of the purity of the compound and the separation and purification. If the melting point deviates from this range, it implies that the compound may contain impurities and needs to be further refined.
    In addition to its solubility, 4- (bromomethyl) -2 -fluoro-1 -nitrobenzene is insoluble in water. Water is a common solvent, and this compound is insoluble in water due to its own molecular structure and weak interaction between water molecules. However, it is soluble in organic solvents such as dichloromethane, chloroform, and ether. This solubility property is of great significance in the extraction of organic synthesis, the selection of reaction media, etc. For example, in some organic reactions, a suitable organic solvent needs to be selected to ensure that the reactants are fully mixed and the reaction proceeds smoothly, and the above soluble organic solvent may be an appropriate choice.
    In addition, the density of the compound is also its physical properties. Although the exact value or the measurement conditions are slightly different, it is roughly within a certain range. The determination of density is indispensable in the measurement of materials in chemical production, mixing ratio control, etc. Only by knowing its density can the dosage of each substance in the reaction system be accurately planned to achieve the desired reaction effect.
    In summary, the physical properties of 4- (bromomethyl) -2 -fluoro-1 -nitrobenzene, such as appearance, melting point, solubility and density, are of great significance in chemical research and industrial practice, laying the foundation for in-depth exploration of its chemical properties and applications.
    What are the chemical properties of 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene?
    4- (bromomethyl) -2 -fluoro-1 -nitrobenzene, this is an organic compound with unique chemical properties. In its structure, bromomethyl, fluorine atoms and nitro are connected to the benzene ring, which has a profound impact on its properties.
    Let's talk about its physical properties first. It may be a solid at room temperature due to intermolecular forces. From the perspective of chemical properties, bromomethyl is quite active. Bromine atoms are easy to leave, making the compound prone to nucleophilic substitution reactions. If nucleophilic reagents such as alcohols and amines are present, bromine atoms will be replaced by nucleophilic reagents to form new organic compounds. This reaction is widely used in the field of organic synthesis, and can be used to construct carbon-carbon bonds, carbon-heteroatom bonds, etc.
    Nitro is a strong electron-absorbing group, which will reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution reaction of the benzene ring. However, under certain conditions, electrophilic substitution can still occur, but the reaction conditions are harsh, and the substitution positions are selective, mostly occurring in the nitro interposition. The fluorine atom has a large electronegativity, which will affect the distribution of the benzene ring electron cloud, and also plays a role in the reaction activity and selectivity.
    In addition, 4- (bromomethyl) -2-fluoro-1-nitrobenzene may have certain oxidizing properties, resulting from the Under the action of suitable reducing agents, nitro groups can be reduced to form different functional groups such as amino groups, which provides new paths and possibilities for organic synthesis. In short, this compound has great significance in the field of organic synthesis and chemistry research due to its unique structure.
    What are the synthesis methods of 4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene
    The synthesis of 4 - (bromomethyl) -2 - fluoro - 1 - nitrobenzene has attracted much attention in the field of organic synthesis. This compound has important applications in many fields such as medicinal chemistry and materials science.
    The synthesis method can be initiated by the corresponding halogenated aromatic hydrocarbon. First, 2 - fluoro - 1 - nitrobenzene is used as a raw material, and bromomethyl is introduced through bromomethylation. This reaction usually requires a suitable solvent, such as dichloromethane, with Lewis acids such as ZnCl ² as catalysts, interacting with polyformaldehyde and hydrobromic acid. Whether the reaction conditions are mild or not depends on the amount of catalyst, reaction temperature and time. In general, the temperature should be controlled between 0 ° C and room temperature, and the reaction takes several hours to obtain the target product.
    Furthermore, 2-fluoro-1-nitrobenzoic acid can also be used as the starting material. First convert it into the corresponding acid chloride, and reagents such as thionyl chloride can be used. Then 2-fluoro-1-nitrobenzyl alcohol is obtained by reduction reaction, and then brominated with brominating reagents such as phosphorus tribromide or hydrobromic acid to obtain 4- (bromomethyl) -2-fluoro-1-nitrobenzene. Although there are slightly more steps in this path, the reaction selectivity of each step is higher, and the product purity is also good.
    Or it can be coupled with bromomethyl-containing reagents by aryl halide. This requires the selection of suitable coupling catalysts, such as palladium catalytic systems. In the presence of a base, the reaction in a suitable solvent can also achieve the synthesis of the target compound. The reaction conditions need to be carefully regulated to ensure the high efficiency and selectivity of the reaction.
    There are many methods for synthesizing 4- (bromomethyl) -2 -fluoro-1 -nitrobenzene, and each method has its own advantages and disadvantages. The optimal synthesis path needs to be carefully selected according to actual needs and conditions.
    4- (Bromomethyl) -2-Fluoro-1-Nitrobenzene What are the precautions in storage and transportation
    4- (bromomethyl) -2-fluoro-1-nitrobenzene is also an organic chemical. During storage and transportation, many matters need to be paid attention to.
    First words storage. This substance has certain chemical activity and potential danger, so it should be placed in a cool, dry and well-ventilated place. Avoid direct sunlight, cover light or cause photochemical reactions, damage its quality or cause danger. Temperature also needs to be controlled. Excessive temperature can promote its decomposition or accelerate chemical reactions. Generally, it is suitable to store in a low temperature environment, but it should also be prevented from freezing and causing the container to break. Furthermore, it must be stored separately from oxidizing agents, reducing agents, alkalis, etc. It is easy to cause chemical reactions due to contact with them, or even cause the risk of combustion and explosion. Where it is stored, it is necessary to prepare corresponding fire and leakage emergency treatment equipment to be prepared.
    As for transportation. Before transportation, it is necessary to ensure that the packaging is intact. The packaging materials must have good sealing and corrosion resistance to prevent material leakage. During transportation, the driving should be stable, avoid bumps and violent vibrations, so as to avoid damage to the packaging. And the transportation vehicle should have obvious dangerous chemical labels, and the transportation personnel must also be professionally trained to be familiar with its characteristics and emergency treatment methods. In case of leakage during transportation, immediate measures should be taken to evacuate the surrounding personnel, isolate the leakage area, and choose the appropriate treatment method according to the leakage situation, such as absorbing with inert materials such as sand and vermiculite, or neutralizing with suitable chemical reagents. Do not allow it to spread, so as not to endanger the environment and personnel safety.