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What are the main uses of 4-Bromomethyl-1-Cyclohexyl-2-Trifluoromethylbenzene?
4-Bromomethyl-1-cyclohexyl-2-trifluoromethylbenzene, which has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Because its structure contains bromomethyl, cyclohexyl and trifluoromethyl, it can introduce other functional groups through various chemical reactions to form complex organic molecules.
For example, bromomethyl has good activity and can react with many nucleophiles to initiate nucleophilic substitution. In case of alcohol nucleophiles, ether compounds can be formed; in case of amine nucleophiles, amine substitution products can be prepared. Through such reactions, organic compounds with specific properties and structures can be synthesized, which is of great significance in the fields of medicinal chemistry and materials science.
In the process of drug development, trifluoromethyl is introduced into organic molecules, which can often improve the physical and chemical properties of drugs, such as improving fat solubility, helping drugs to more easily penetrate biofilms, enhancing bioavailability; or enhancing the metabolic stability of molecules and prolonging the action time of drugs in vivo. Therefore, 4-bromomethyl-1-cyclohexyl-2-trifluoromethylbenzene may provide a key starting material for the development of new drugs.
In the field of materials science, fluorinated compounds often have unique properties, such as excellent weather resistance, chemical stability and low surface energy. Polymer materials synthesized from this material can be used to prepare special coatings, high-performance engineering plastics, etc., to meet the needs of different fields for special properties of materials. In short, it has important application value in many fields such as organic synthesis, drug development and materials science.
What are the physical properties of 4-Bromomethyl-1-Cyclohexyl-2-Trifluoromethylbenzene?
4-Bromomethyl-1-cyclohexyl-2-trifluoromethylbenzene, this is an organic compound with unique physical properties. Its properties are usually colorless to pale yellow liquid or solid, depending on temperature and purity.
Looking at its melting point, due to the molecular structure containing different groups such as cyclohexyl, trifluoromethyl and bromomethyl, the intermolecular force is complicated. Generally speaking, cyclohexyl can increase the intermolecular van der Waals force, and the fluorine atom of the trifluoromethyl gene has a large electronegativity, which can cause the polarity of the molecule to change and affect the melting point. The melting point of the compound is either in a relatively low range, or due to the steric resistance and interaction of the substituents, the orderly arrangement of the molecules is disturbed, and the melting point is not high. The boiling point or due to the molecular mass and polarity, is in a moderate range, and the specific value needs to be accurately determined by experiments.
In terms of solubility, due to its organic properties, it is easily soluble in common organic solvents, such as dichloromethane, chloroform, ether, etc. Due to the principle of "similar miscibility", the molecular structure of the compound is similar to the polarity of organic solvents, which can form intermolecular interactions and promote dissolution. However, the solubility in water is poor, because its non-polar part accounts for a large proportion, it is difficult to form effective interactions with water molecules.
Density is also an important physical property, which is determined by the type and number of atoms in the molecule. Containing bromine atoms and trifluoromethyl, its density is relatively large, or greater than that of common hydrocarbons. The specific value needs to be
In addition, the compound has certain chemical activity due to its bromomethyl content, which can participate in a variety of organic reactions and may have application value in the field of organic synthesis. However, its physical properties not only determine its own existence state, but also have a significant impact on its behavior and application in the reaction.
What is 4-Bromomethyl-1-Cyclohexyl-2-Trifluoromethylbenzene synthesis method?
The synthesis of 4-bromomethyl-1-cyclohexyl-2-trifluoromethylbenzene is an important topic. To obtain this compound, several ways can be taken.
First, an aromatic compound containing cyclohexyl can be used as the starting material. Choose an appropriate reaction condition to introduce a specific substituent to the benzene ring. In a suitable reaction system, the specific position of the benzene ring is combined with the reagent containing trifluoromethyl to form an intermediate containing trifluoromethyl. This step requires careful selection of reaction conditions, such as temperature and catalyst, to ensure the selectivity and yield of the reaction.
Then, for the intermediate with trifluoromethyl and cyclohexyl, bromomethyl is introduced. This process may be achieved by halomethylation. In a suitable solvent and reaction environment, appropriate halogenating reagents and initiators are added to promote the reaction of the intermediate with the halogenating reagent to generate bromomethyl at the specified position on the benzene ring. This step also requires precise regulation of the reaction parameters to obtain the ideal product.
Or, another strategy is to construct a benzene derivative containing bromomethyl first, and then introduce cyclohexyl and trifluoromethyl in turn. On the basis of the initial bromomethyl benzene compound, the cyclohexyl part is accessed through reactions such as nucleophilic substitution to form an intermediate containing bromomethyl and cyclohexyl. After that, trifluoromethyl is introduced into the benzene ring through specific reactions, such as electrophilic substitution or metal catalysis, and the final product is 4-bromomethyl-1-cyclohexyl-2-trifluoromethylbenzene.
No matter what kind of synthesis path is adopted, it is necessary to pay attention to the optimization of the reaction conditions at each step, including the proportion of reactants, reaction temperature, reaction time, etc., in order to improve the purity and yield of the product, and the safety and operability of the reaction should be paid attention to, so as to effectively synthesize this compound.
What is the price range of 4-Bromomethyl-1-Cyclohexyl-2-Trifluoromethylbenzene in the market?
4-Bromomethyl-1-cyclohexyl-2-trifluoromethylbenzene, this product is not a common product in the market, and its price range is difficult to determine. Due to the supply and demand situation in the market, the quality of the product, and the difficulty of preparation, its price is determined.
If its past market traces are studied, its exact price is rarely seen. These compounds are mostly required for specific scientific research and are not widely distributed in the general chemical market. Its synthesis process is very complex, and the materials used are rare, so the price is high; or there is little demand, resulting in rare production and variable price.
Or there is a merchant specializing in specialty chemicals who hides this strange product, but its pricing is random, or it fluctuates up and down depending on the amount required by the buyer. If the amount used is small, or sold by the gram, the price may reach several hundred yuan per gram; if the quantity is large, the price per gram may be slightly reduced after negotiation.
If you want to know the exact price, you should consult a merchant specializing in specialty chemicals, or negotiate with the company that supplies scientific research materials, and state the required quantity and purity in detail, in order to obtain a more accurate price.
What are 4-Bromomethyl-1-Cyclohexyl-2-Trifluoromethylbenzene storage conditions?
4-Bromomethyl-1-cyclohexyl-2-trifluoromethylbenzene is one of the organic compounds. Its storage method is quite important, and it is related to the quality and safety of this compound.
When this compound is stored, the first environment is dry. Due to its nature or susceptibility to water vapor, reactions such as hydrolysis will occur, which will damage its purity and performance. Therefore, it should be stored in a dry place and protected from moisture. For example, a desiccant is placed on the side of the reservoir to absorb water vapor and maintain its dry state.
Second, temperature is also critical. When a moderate low temperature is appropriate, it should not be heated. Under high temperature, the molecular activity increases greatly, or it may cause adverse reactions such as decomposition and polymerization. Generally speaking, it is recommended to store in a cool place with a temperature between 2 and 8 degrees Celsius, which can stabilize its chemical structure and reduce the risk of deterioration.
Furthermore, this substance should avoid contact with oxidants, strong bases, etc. Because its structure contains groups such as bromomethyl and trifluoromethyl, it is easy to react violently when encountering oxidants and strong bases, or to cause fire or explosion. Therefore, when storing, it should be placed separately from such substances, in a thick-walled container, and marked to indicate its characteristics to prevent mismixing.
Also, the storage place should be well ventilated. If this substance evaporates in a confined space, the gas accumulates, which not only harms human health, but also increases the risk of explosion. Good ventilation can allow the volatile gas to escape in time, ensuring the safety of the environment.
Store 4-bromomethyl-1-cyclohexyl-2-trifluoromethylbenzene in a dry, cool and ventilated place, avoid contact with incompatible objects, and store it in a thick-walled container, so as to ensure its quality and safety for subsequent use.