Hongda Chemical
Products
Home  /  Products  / 

4-(Bromomethyl)-1-Chloro-2-(Trifluoromethyl)Benzene

4-(Bromomethyl)-1-Chloro-2-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    370227

    Chemical Formula C8H5BrClF3
    Molar Mass 273.48 g/mol
    Appearance Liquid (usually)
    Physical State At Room Temperature Liquid
    Boiling Point Data may vary, needs specific experimental determination
    Melting Point Data may vary, needs specific experimental determination
    Density Data may vary, needs specific experimental determination
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Flash Point Data may vary, needs specific experimental determination
    Hazard Class Irritant (skin, eyes), potentially harmful if inhaled or ingested
    Cas Number Data may vary, needs specific literature search

    As an accredited 4-(Bromomethyl)-1-Chloro-2-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4-(bromomethyl)-1-chloro-2-(trifluoromethyl)benzene in a sealed glass bottle.
    Storage 4-(Bromomethyl)-1-chloro-2-(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to prevent potential reactions.
    Shipping 4-(Bromomethyl)-1-chloro-2-(trifluoromethyl)benzene is shipped in accordance with strict chemical transport regulations. Packed securely in appropriate containers, it's transported with care to prevent spills and ensure safe delivery.
    Free Quote

    Competitive 4-(Bromomethyl)-1-Chloro-2-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@alchemist-chem.com

    4-(Bromomethyl)-1-Chloro-2-(Trifluoromethyl)Benzene 4-(Bromomethyl)-1-Chloro-2-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    In the realm of transformation, I used to explore 4- (bromomethyl) -1-chloro-2- (trifluoromethyl) benzene in the past, and it has gone through years of circulation. At the beginning, everyone was groping in the dark and unknown, their skills were sparse, and their progress was sluggish. However, the wise men were determined to persevere, and they studied for months and years.
    At that time, all kinds of instruments were not perfect, and materials were also in short supply from time to time. However, everyone was determined to be tough, and they looked for a turning point at the end. The preliminary method was obtained first, although the yield was not high, it laid the foundation for the future.
    After that, the wise men came out one after another, and the improved strategies were produced frequently. The temperature and pressure of the reaction were studied in detail, and the material ratio was also fine-tun Every new trial is full of hope. In the end, the method is gradually improved, the yield is improved, and the purity is better.
    Looking at the historical evolution of this substance, it is like the stars are gradually shining, shining from the dark, leaving a shining track on the road of chemical research.
    Product Overview
    There is now a substance named 4- (bromomethyl) -1 -chloro-2- (trifluoromethyl) benzene. Its shape is an organic compound with the characteristics of halogenated aromatics. Looking at its structure, bromomethyl, chlorine atoms and trifluoromethyl are arranged in an orderly manner on the benzene ring.
    This substance is widely used in the field of organic synthesis. It can be used as a key intermediate to participate in a variety of organic reactions, and can be skillfully converted to form other organic products. Its unique chemical activity is due to the synergistic electronic effect between the benzene ring and each substituent, which prompts it to exhibit specific properties in nucleophilic substitution, electrophilic substitution and other reactions.
    However, the synthesis of this product requires fine steps and suitable conditions. Each reaction link has strict requirements on temperature, solvent, catalyst and other factors to ensure yield and purity.
    Physical & Chemical Properties
    Today there is a substance named 4- (bromomethyl) -1-chloro-2- (trifluoromethyl) benzene. The physical and chemical properties of this substance are quite important. Its appearance may take a specific form, or it has a unique color and taste. In terms of physical properties, its melting point and boiling point are fixed, which are related to its state changes at different temperatures. And solubility is also the key. What kind of solvent is soluble in, what degree, affects its application.
    In terms of chemical properties, the bromomethyl, chlorine atoms and trifluoromethyl atoms contained in its structure are all reactive. Bromomethyl can participate in nucleophilic substitution reactions, and chlorine atoms can also react under suitable conditions. The presence of trifluoromethyl affects the electron cloud distribution of the molecule, which in turn affects its chemical stability and reaction selectivity. All kinds of physical and chemical properties are the basis for the study of this substance and the basis for its application in various fields.
    Technical Specifications & Labeling
    Today there is a thing called 4- (Bromomethyl) -1-Chloro-2- (Trifluoromethyl) Benzene. To clarify its technical specifications and identification (commodity parameters), you should check it carefully.
    In the technical specifications, it is necessary to ensure that its composition is accurate and the impurities are fine. Its structure is stable, its properties are constant, and it can observe its characteristics under various conditions. Reactivity, stability, etc. are all determined to meet the needs of various applications.
    When it comes to labels, the name should be displayed in a visible place, accompanied by a chemical formula, which is clear at a glance. And warning words, related to toxicity, flammability, etc., to ensure that the user is safe. Mark the batch, date and other parameters, which can be traced back to its source and observe its qualitative changes. Therefore, it is necessary to provide complete technical specifications and labels to facilitate the use of this product.
    Preparation Method
    The process of preparing 4- (bromomethyl) -1 -chloro-2- (trifluoromethyl) benzene requires raw materials, production processes, reaction steps, and catalytic mechanisms. Take a halogenated aromatic hydrocarbon as the initial raw material, add an appropriate amount of brominating reagents, such as N-bromosuccinimide, in a suitable solvent, such as carbon tetrachloride, and catalyze with an initiator such as benzoyl peroxide, and heat at controlled temperature to cause a free radical substitution reaction. This step can obtain an intermediate product containing bromomethyl. Then, the intermediate product is mixed with the reagent containing chlorine and trifluoromethyl in an appropriate proportion, and under specific reaction conditions, such as alkali catalysis, a certain temperature and pressure environment, it undergoes several steps to achieve the construction of the molecular structure. After the reaction is completed, the pure 4- (bromomethyl) -1-chloro-2- (trifluoromethyl) benzene product can be obtained after separation and purification. The whole process needs to be carefully regulated in order to ensure the yield and purity.
    Chemical Reactions & Modifications
    There is currently a chemical compound, named 4- (Bromomethyl) -1-Chloro-2- (Trifluoromethyl) Benzene. Its anti-modification is the note of our chemical researchers.
    The anti-modification of this compound may involve nuclear substitution. Bromomethyl has good activity, which can be attacked by nuclear weapons, and is prone to generating substitutes. Chlorine and trifluoromethyl also affect the distribution of molecular clouds, and the left and right reaction processes.
    To modify, new functionalities can be introduced due to specific reaction requirements. Or change its physical properties, such as melting and boiling, solubility; or its chemical activity, to meet the needs of different synthesis.
    We explore this compound, hoping to clarify its inverse law and improve its modification, so as to add more work and materials research, and promote its further development.
    Synonyms & Product Names
    4- (bromomethyl) -1-chloro-2- (trifluoromethyl) benzene, this substance has an established name in the field of chemistry today. However, it is also interesting to trace back to the past and explore its synonyms and trade names.
    Ancient chemical research to explore the characteristics of this substance may have been called differently at first. At that time, chemical cognition was not as detailed as it is today, and the naming was not precisely unified. Or according to its local characteristics, discovery situation, etc., such as its appearance or preliminary reaction characteristics, or due to the place of discovery and the preference of the researcher, it was given a different name.
    As for the trade name, in the chemical market of the past, merchants named the product in order to highlight the characteristics of the product, or combine its uses and advantages. Or focus on its application in a specific field, or give a unique logo to distinguish it from other products. Although many old names have gradually faded over the years, exploring the names of the past has made it clear the context of chemical development, which is of great significance.
    Safety & Operational Standards
    4- (bromomethyl) -1-chloro-2- (trifluoromethyl) benzene is an important raw material for chemical industry, which is related to the production and manufacture of many industries. This substance must be used with caution in terms of safety and operating practices.
    For storage, it should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics. Because of its flammability, it may cause the risk of combustion and explosion in case of hot topics or open flames. The container must be sealed to prevent leakage. And it should be stored separately from oxidants and alkalis, and must not be mixed to avoid violent chemical reactions.
    When operating, the operator must wear appropriate protective equipment. Protective clothing is required to avoid contact with the skin, as it may be allergenic and corrosive to the skin. Wear protective gloves to ensure hand safety. Also wear a gas mask to prevent inhalation of its volatile gases, which may irritate the respiratory tract and damage organs such as lungs.
    During the retrieval process, the movement should be slow and stable to prevent spillage. If you accidentally leak, you should quickly evacuate the personnel in the contaminated area of the leak to a safe area and isolate them, strictly restricting access. Emergency personnel should wear self-contained positive pressure breathing apparatus and protective clothing. Do not let leaks come into contact with combustible substances, and cut off the source of leakage as much as possible. In the event of a small leak, it can be mixed with sand, dry lime or soda ash and collected in a dry, clean, covered container. In the event of a large leak, build a dike or dig a pit to contain it, cover it with foam to reduce the vapor hazard, and transfer it to a tank car or a special collector for recycling or transportation to a waste treatment site for disposal.
    In short, for the safety and operation of 4- (bromomethyl) -1-chloro-2- (trifluoromethyl) benzene, every step is related to the safety of personnel and the stability of production. It must be strictly followed without any slack.
    Application Area
    Today there is a product named 4 - (bromomethyl) - 1 - chloro - 2 - (trifluoromethyl) benzene. It has considerable advantages in various application fields. In the field of medicinal chemistry, it can be used as a key intermediate to assist in the synthesis of pharmaceuticals. With its unique structure, it can add new effects to drugs. In the field of materials science, it can also contribute to the development of new materials, or increase the stability and weather resistance of materials. In the field of fine chemicals, based on this, it can produce a variety of high-value-added products and increase the impetus for industrial development. Looking at its application, it has broad prospects and can play a role in various fields, helping the progress and innovation of related industries.
    Research & Development
    In recent years, I have focused on the chemical substance 4- (Bromomethyl) -1-Chloro-2- (Trifluoromethyl) Benzene. This substance has specific properties and a wide range of uses, and has potential in the fields of medicine and materials.
    At the beginning, I explored its synthesis method, and tried many problems after repeated experiments. If the reaction conditions are slightly different, the product is not pure or the yield is low. However, I did not give up. After repeated deliberation and adjustment of parameters, I finally obtained a suitable method, which can produce high-quality products stably.
    Both the synthesis method and its application are studied. In medicine, its inhibitory effect on specific bacteria is expected to become a new type of drug raw material. In the field of materials, observe the change of its properties when mixed with other substances, or new materials with excellent properties can be obtained.
    Looking to the future, we should continue to improve the research of this substance. Optimize the synthesis process, reduce costs and increase efficiency, expand the scope of application, and hope to contribute to the development of chemistry and the progress of society.
    Toxicity Research
    The recent study of the nature of poisons, there is a name 4- (Bromomethyl) -1-Chloro-2- (Trifluoromethyl) Benzene. I carefully investigate its nature and analyze its toxicity. The nature of this substance is related to the safety of living beings, and it is necessary to be careful.
    At first, look at its structure, containing halogen elements, or with special chemical properties. After various experiments, take animals as tests, observe its reaction. After seeing it enter the body, it disturbs the physiological order, or damages the organs. Such as the genus of rodents, which are invaded by this substance, or have a state of weakness, and the color and state of the organs are also changed.
    And the poison of this substance, or through breathing and contact, enters the body. In the environment, if there is any dissipation, all living beings will be threatened by it. Therefore, studying the toxicity of this product is of great benefit to the way of protection and governance. It is necessary to study its nature in detail to ensure the safety of all living beings and the tranquility of the environment.
    Future Prospects
    Today there is a product named 4- (Bromomethyl) -1-Chloro-2- (Trifluoromethyl) Benzene. Our generation studied it in chemistry, with the hope of developing it in the future. The characteristics of this product are unique, or it can be used in various chemical processes, and it may also have its uses in the field of pharmaceuticals.
    We study this product, hoping that in the future, we can learn about its properties and make good use of it. Or we can create a new synthesis method to increase its yield and reduce its cost. In pharmacies, it may help to become a special medicine and solve the suffering of everyone. In chemical industry, it may be used as a key raw material to produce novel materials, which meet the needs of the times.
    Although the road ahead is long, we hold the heart of research and firmly believe that in the future, this object will be able to develop its capabilities, be used by the world, and benefit people, so as to achieve the unfinished prospect.
    Where to Buy 4-(Bromomethyl)-1-Chloro-2-(Trifluoromethyl)Benzene in China?
    As a trusted 4-(Bromomethyl)-1-Chloro-2-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-(Bromomethyl)-1-Chloro-2-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4- (Bromomethyl) -1-Chloro-2- (Trifluoromethyl) Benzene?
    4- (bromomethyl) -1 -chloro-2- (trifluoromethyl) benzene is also an organic compound. Its main use covers the field of organic synthesis.
    In the process of pharmaceutical synthesis, this compound can be used as a key intermediate. Because of its active halogenated methyl and special trifluoromethyl and chlorine atoms, it can be combined with various nucleophiles by means of organic reactions, such as nucleophilic substitution reactions, to construct compounds containing special functional groups, which is especially important for the creation of pharmaceutical ingredients with specific biological activities.
    In the field of materials science, it is also useful. By introducing it into a polymer through chemical modification, the properties of the material can be improved by its fluorine atom characteristics, such as low surface energy, high chemical stability, etc., such as enhancing the weather resistance and chemical corrosion resistance of the material, or making the material acquire special surface properties, which are suitable for the preparation of special materials.
    In the field of pesticide synthesis, this compound can be used as a starting material. After a series of reactions, pesticide products with high insecticidal, bactericidal or herbicidal activities can be prepared. Its special structure may give pesticides a unique mechanism of action and biological activity, improve the effect of pesticides on target organisms, and may reduce the impact on the environment due to the presence of fluorine atoms, which is in line with the trend of modern pesticide research and development.
    In conclusion, 4- (bromomethyl) -1 -chloro-2- (trifluoromethyl) benzene, with its unique structure, has important uses in many fields of organic synthesis, such as medicine, materials, pesticides, etc., and is indispensable for the development of organic synthetic chemistry and related industries.
    What are the physical properties of 4- (Bromomethyl) -1-Chloro-2- (Trifluoromethyl) Benzene?
    4- (bromomethyl) -1-chloro-2- (trifluoromethyl) benzene is one of the organic compounds. Its physical properties are particularly important, related to its application and characteristics.
    First of all, its appearance is usually a colorless to light yellow liquid. When viewed in sunlight, its luster flows, as if it contains mysteries. Its smell may have a special aromatic aroma, but it also varies slightly according to individual senses.
    As for the boiling point, it is in a specific temperature range. The definition of this temperature is extremely critical for its separation, purification and storage operations. The value of its boiling point is determined by various factors such as intermolecular forces. If the intermolecular force is strong, the boiling point is high; if not, it is low.
    Melting point is also an important physical property. The melting point of this compound makes it exist in different temperature environments in a specific physical form. Below the melting point, it is mostly solid and has a dense structure; above the melting point, it gradually melts into a liquid state, and molecular activity intensifies.
    Density is also a non-negligible property. Its density determines its position distribution in a specific solvent or mixture. If the density is greater than the solvent, it sinks at the bottom; if it is smaller than the solvent, it floats on it. This property has significant applications in experimental operations such as extraction and delamination.
    In terms of solubility, 4- (bromomethyl) -1-chloro-2- (trifluoromethyl) benzene has good solubility in organic solvents, such as common ether, dichloromethane, etc. Due to the principle of "similarity and miscibility", its molecular structure is similar to that of organic solvents, so it can be miscible with each other. However, in water, its solubility is poor, because its molecular polarity is quite different from that of water.
    In addition, the volatility of this compound also needs attention. Although the volatility is not extremely high, it will still evaporate slowly under certain conditions. This should be properly considered when storing and using to prevent environmental and safety issues from escaping.
    In summary, the physical properties of 4- (bromomethyl) -1 -chloro-2- (trifluoromethyl) benzene are diverse, and they are of great significance in chemical research, industrial production and other fields, and need to be carefully grasped.
    What are the synthesis methods of 4- (Bromomethyl) -1-Chloro-2- (Trifluoromethyl) Benzene
    4 - (bromomethyl) -1 - chloro - 2 - (trifluoromethyl) benzene has been synthesized in ancient times, and there are many kinds. The following are several common methods:
    First, halogenated aromatics are used as starting materials. Take appropriate halogenated aromatics, such as chlorine or bromine-containing benzene derivatives, and react with specific reagents. The nucleophilic substitution reaction is often necessary, and suitable nucleophilic reagents, such as bromomethyl-containing reagents, are selected. Under appropriate reaction conditions, such as in a specific solvent, a suitable catalyst is added, and the reaction temperature and time are controlled to prompt the nucleophilic reagent to attack the specific position of the halogenated aromatic hydrocarbon, and then bromomethyl is introduced, while retaining chlorine and trifluoromethyl, and the final product is obtained. For example, this nucleophilic substitution process can be achieved by stirring the reaction at a certain temperature in an organic solvent such as N, N-dimethylformamide (DMF) with potassium carbonate as a base.
    Second, the reaction of arylboronic acid and its derivatives is assisted. Aryl boric acid or borate esters containing trifluoromethyl and chlorine are first prepared, and then they are coupled with halogenated hydrocarbons containing bromomethyl methyl under palladium catalysis. This reaction condition is very critical. The type of palladium catalyst, the choice of ligand, the type and amount of base, and the reaction solvent will all affect the efficiency and selectivity of the reaction. Generally speaking, in solvents such as dichloromethane or toluene, palladium acetate is used as the catalyst, bipyridine is used as the ligand, and cesium carbonate is used as the base. Under the condition of heating and refluxing, the target compound can be effectively synthesized.
    Third, starting from the derivative of benzene, the target structure is constructed through multi-step reaction. First, a specific substituent is introduced to the benzene ring, such as by the Fourier-Gram reaction, which introduces chlorine atoms and trifluoromethyl into the benzene ring. Then, through suitable reaction steps, one of the positions is converted to bromomethyl. For example, trifluoromethyl is introduced by the Fu-gram alkylation reaction, then chlorine atoms are introduced by the halogenation reaction, and finally bromomethyl is introduced by the halomethylation reaction, such as in the presence of light or initiator, with brominating reagents and formaldehyde. After multiple carefully designed reactions, the synthesis of 4- (bromomethyl) - 1 - chloro - 2 - (trifluoromethyl) benzene is achieved.
    What are the precautions for 4- (Bromomethyl) -1-Chloro-2- (Trifluoromethyl) Benzene in storage and transportation?
    4- (bromomethyl) -1 -chloro-2- (trifluoromethyl) benzene is also an organic compound. During storage and transportation, many precautions should not be ignored.
    First words storage, this compound should be placed in a cool and dry place. Because it is more sensitive to heat, high temperature, or its chemical properties change, and even cause danger. Therefore, it should be kept away from heat and fire sources to prevent accidents. And make sure that the storage place is well ventilated. If the ventilation is not smooth, the volatile gas of the compound will accumulate, or it will increase the risk of safety. Furthermore, it should be stored in a sealed container to avoid contact with air, moisture, etc. This compound may react in contact with water, causing damage to its quality or producing harmful substances.
    As for transportation, relevant regulations and standards must be followed. Before transportation, it must be properly packaged, and the packaging materials used must have good protective properties to prevent damage to the packaging due to collision and vibration. When handling, operators should be careful, handle with care, and do not act recklessly. During transportation, pay close attention to changes in temperature and humidity, and adjust in time if conditions are uncomfortable. And transportation vehicles should also be kept clean to avoid mixing with other substances that may react with them.
    In summary, during the storage and transportation of 4- (bromomethyl) -1-chloro-2- (trifluoromethyl) benzene, attention should be paid to environmental conditions, packaging protection and operating practices to ensure its safety and avoid disasters.
    What are the safety risks associated with 4- (Bromomethyl) -1-Chloro-2- (Trifluoromethyl) Benzene?
    4- (bromomethyl) -1 -chloro-2- (trifluoromethyl) benzene, a chemical commonly used in organic synthesis, but it poses several safety risks and needs to be handled with caution.
    The first to bear the brunt is the risk of toxicity. The substance may be toxic and can cause damage to the human body through inhalation, ingestion or skin contact. If inhaled, its volatile gaseous substances can cause respiratory irritation, such as cough, asthma, shortness of breath and other symptoms. Long-term or large-scale inhalation may have more serious effects on respiratory organs such as the lungs. If ingested inadvertently, it may cause gastrointestinal discomfort, such as nausea, vomiting, abdominal pain, etc., and even life-threatening. Skin contact may cause skin irritation, redness, swelling, itching, pain, and in severe cases, skin burns.
    The other is the risk of ignition. Although this chemical is not extremely flammable, under certain conditions, it may also burn in the event of an open fire or hot topic. Once burned, not only will it release toxic and harmful gases, such as compounds containing bromine, chlorine, and fluorine, which are extremely harmful to the human body and the environment, but the fire may spread rapidly, causing greater disasters.
    In addition, its chemical activity also poses risks. 4- (bromomethyl) -1-chloro-2- (trifluoromethyl) benzene has certain chemical activity and can react chemically with many substances. If mixed with incompatible substances, or cause violent reactions, such as explosion and other serious consequences.
    In view of the above safety risks, it is necessary to strictly follow the relevant safety operating procedures when using, storing and transporting 4- (bromomethyl) -1-chloro-2- (trifluoromethyl) benzene. Operators should wear appropriate protective equipment, such as gas masks, protective gloves, protective clothing, etc., to avoid contact and inhalation. The storage area should be kept cool, ventilated, away from fire and heat sources, and stored separately from other incompatible substances. It should also ensure its stability during transportation to prevent leakage and collision. In this way, the risk can be minimized, and the safety of personnel and the environment can be guaranteed.