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4-Bromol-(Difluoromethoxy)-2-Fluorobenzene

4-Bromol-(Difluoromethoxy)-2-Fluorobenzene

Hongda Chemical

    Specifications

    HS Code

    210365

    Chemical Formula C7H4BrF3O
    Molar Mass 241.005 g/mol
    Appearance likely a colorless to pale - colored liquid
    Solubility In Water low (due to non - polar aromatic and fluorinated groups)
    Solubility In Organic Solvents soluble in common organic solvents like dichloromethane, chloroform, etc.

    As an accredited 4-Bromol-(Difluoromethoxy)-2-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4 - bromo - (difluoromethoxy) - 2 - fluorobenzene in a sealed, labeled chemical bottle.
    Storage 4 - bromo - (difluoromethoxy) - 2 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Store separately from oxidizing agents, reducing agents, and other reactive chemicals to prevent potential chemical reactions.
    Shipping 4 - bromo - (difluoromethoxy) - 2 - fluorobenzene is shipped in accordance with strict chemical transportation regulations. It's packaged securely in suitable containers to prevent leakage, and transported by carriers licensed for handling such chemicals.
    Free Quote

    Competitive 4-Bromol-(Difluoromethoxy)-2-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@alchemist-chem.com.

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    4-Bromol-(Difluoromethoxy)-2-Fluorobenzene 4-Bromol-(Difluoromethoxy)-2-Fluorobenzene
    General Information
    Historical Development
    4 - Bromo - (Difluoromethoxy) - 2 - Fluorobenzene is a unique compound. Its historical evolution is really meaningful. In the past, chemical research was the beginning, and many substances were yet to be discovered. At that time, this compound was hidden.
    With the passage of time, chemical skills have become more and more exquisite. Researchers have worked tirelessly to analyze various reactions and explore molecular mysteries. After countless attempts and improvements, synthetic methods have gradually emerged. In the early stage, there may be difficulties and obstacles, the yield is not high, and impurities are complicated.
    However, scholars are persevering and repeatedly adjust the reaction conditions and improve the process flow. From the screening of raw materials to the control of reaction temperature and time, it is all meticulous. Finally, a better method can be used to stabilize the preparation of this compound, making it stand out in the field of chemistry, paving the way for subsequent research and application.
    Product Overview
    4 - Bromol- (Difluoromethoxy) - 2 - Fluorobenzene is an important chemical synthesis product. It may be a colorless to slightly yellow liquid with specific physical and chemical properties. The structure of this compound is unique, with bromine atoms, difluoromethoxy and fluorine atoms distributed at specific positions in the benzene ring, giving it special reactivity.
    In the field of organic synthesis, 4 - Bromol- (Difluoromethoxy) - 2 - Fluorobenzene is often a key intermediate. With its structural properties, it can participate in many chemical reactions, such as nucleophilic substitution reactions, laying the foundation for the construction of complex organic molecular structures. It also has potential application value in medicinal chemistry, materials science and other fields, and may assist in the development of new drugs and the creation of functional materials. Through precise synthesis processes, product purity and yield can be effectively controlled to meet the needs of different fields.
    Physical & Chemical Properties
    4-Bromol- (Difluoromethoxy) -2-Fluorobenzene is an organic compound, and its physical and chemical properties are very important. Looking at its physical properties, it is liquid at room temperature and has a specific color and odor. Boiling point, melting point, etc. also have their own values. The boiling point is related to the temperature at which it changes from liquid to gas state, and the melting point is determined when its solid state changes to liquid state.
    When it comes to chemical properties, bromine, fluorine and other atoms in this compound give it active chemical activity. Bromine atoms can participate in substitution reactions and can be replaced by other groups under appropriate conditions. The presence of fluorine atoms enhances molecular stability and affects its polarity and reactivity. Its methoxy structure also participates in chemical reactions and interacts with other reagents, showing unique chemical behaviors. Understanding these physical and chemical properties is of great significance for the study of the synthesis and application of this compound.
    Technical Specifications & Labeling
    4 - Bromol - (Difluoromethoxy) - 2 - Fluorobenzene is also a chemical substance. Its technical regulations and identification (commodity parameters) are essential for the study of this substance. To understand its technical regulations, you should know the method of synthesis, the geometry of raw materials, and the reaction bars, such as temperature, pressure, and duration. The marker contains the characteristics of shape, color, taste, and purity, and also has the important rules for safe storage and transportation. If you want to make this substance, you must follow precise technical regulations and observe safety standards. Check its logo to know its properties, use it correctly, and ensure the safety of production and smooth research.
    Preparation Method
    4-Bromol- (Difluoromethoxy) -2-Fluorobenzene is an important organic compound. The raw material selection is crucial for its preparation. When the initial raw material is a benzene ring derivative containing bromine, fluorine and suitable benzene ring. The synthesis process is as follows: First, the benzene ring derivative containing bromine is reacted with a specific reagent to introduce fluorine atoms. This step requires precise control of the reaction conditions, such as temperature and catalyst dosage. Then, through ingeniously designed steps, the difluoromethoxy group is successfully integrated into the benzene ring. The reaction steps are rigorous and orderly, and each step needs to be carefully controlled. In terms of reaction equipment, a suitable reactor should be selected, and the stirring rate and heating method should be adjusted according to the reaction characteristics. Subsequent processing cannot be ignored either. After separation, purification, and other processes, high-purity 4-Bromol- (Difluoromethoxy) -2-Fluorobenzene can be obtained, so as to meet the application requirements in related fields.
    Chemical Reactions & Modifications
    The beauty of chemistry lies in changing the properties of substances and creating new things. Today there is a thing named 4 - Bromol - (Difluoromethoxy) - 2 - Fluorobenzene. Its chemical reaction and modification are related to the expansion of function and the sublimation of efficiency.
    In the process of reaction, it is necessary to examine its structure and its properties. Or select an adaptor and control its temperature and pressure, so that the bromine group and fluoroxy group parts can be changed according to reason to form a new substance. When modifying, consider its combination with other things and consider its existence in the environment. Seek its stability and efficiency, harmless and beneficial.
    Chemists must study the subtle reactions with caution; with innovative ideas, explore the path of modification. Hope to make this substance in the fields of medicine and materials, develop its talents and benefit the world.
    Synonyms & Product Names
    4-Bromo- (difluoromethoxy) - 2-fluorobenzene, in the field of my chemical research, its synonymous name and the name of the commodity are quite worth exploring.
    Guanfu chemical substances have many names, and the synonymous names are based on their structure, properties or inheritance of past research. This 4-bromo- (difluoromethoxy) - 2-fluorobenzene, or other names due to structural similarity and functional group characteristics. The name of the commodity is related to the circulation of the market and the positioning of the manufacturer.
    In our research process, we can clarify its synonymous name, which can be widely searched in various literature, so as not to leak important information due to different names; to gain insight into the name of its commodity, we can know the market supply and demand, and know its application direction.
    Therefore, exploring the synonymous name of 4-bromo- (difluoromethoxy) -2-fluorobenzene and the name of the commodity is of great significance to the advancement of chemical research and the development of the industry, and cannot be ignored.
    Safety & Operational Standards
    4 - Bromo - (Difluoromethoxy) - 2 - Fluorobenzene is a special chemical substance. In its safe production and operation, the following specifications should be followed.
    Suitable for the first environment. The preparation, storage and use of this substance should be in a well-ventilated place. It is appropriate to take mechanical ventilation to keep the concentration of this substance in the air within the safety threshold to avoid its accumulation and danger. And the operating site should avoid open flames and hot topics, and fireworks are strictly prohibited to prevent the risk of deflagration.
    When operating, it must be adapted for protection. Operators should wear chemical safety glasses to protect their eyes from splashing hazards; wear anti-toxic infiltration work clothes to protect their bodies from damage; wear rubber gloves to keep their hands safe.
    When handling, they should be careful to avoid damage to the packaging and containers. If there is a leak in the packaging, take emergency measures immediately. A small amount of leakage should be covered with inert materials such as sand and vermiculite and collected in a closed container; if there is a large amount of leakage, the embankment will be blocked and transferred to a special collector with an explosion-proof pump for proper treatment.
    Storage also has its own rules. The substance should be stored in a cool, dry and well-ventilated warehouse, away from fire and heat sources. The warehouse temperature should not exceed 30 ° C, and the relative humidity should not exceed 80%. It should be stored separately from oxidants and edible chemicals, and should not be mixed. The storage area should be prepared with emergency treatment equipment and suitable containment materials.
    If you come into contact accidentally, take measures to deal with it quickly. Contact the skin, remove the decontamination clothes, and rinse with a large amount of flowing water for more than 15 minutes. If you feel unwell, seek medical attention; contact the eyes, lift the eyelids, rinse with flowing water or normal saline for 15 minutes, and seek medical attention. Inhalers, quickly leave the scene to a fresh air place to keep the respiratory tract smooth. If breathing difficulties, oxygen infusion, and breathing stops, perform artificial respiration and seek medical attention.
    Only by strictly adhering to these safety and operating standards can the safety of 4 - Bromo - (Difluoromethoxy) - 2 - Fluorobenzene related operations be guaranteed without accidents.
    Application Area
    4 - Bromol - (Difluoromethoxy) - 2 - Fluorobenzene is a delicate chemical substance. In today's world, its application field is extensive and crucial.
    In the field of pharmaceutical research and development, this substance may be used as a key intermediate. Through ingenious chemical reactions, it can help synthesize molecules with unique pharmacological activities, or be a good medicine for treating difficult diseases and solving the suffering of all beings.
    In the field of materials science, it can also be used. It may endow materials with special properties, such as improving material stability, optical properties, etc., so that materials can play important functions in high-end scientific and technological products and help the progress of science and technology.
    In the field of agriculture, or can participate in the creation of new pesticides, which is of great benefit to the control of pests and diseases, to ensure the harvest of five grains, and to protect the prosperity of agriculture.
    From this point of view, 4 - Bromol - (Difluoromethoxy) - 2 - Fluorobenzene has significant value in many application fields and has broad prospects. It is a treasure of chemical research and a weapon to promote the development of various industries.
    Research & Development
    I have been dedicated to the research and development of 4 - Bromol- (Difluoromethoxy) - 2 - Fluorobenzene compound for a long time. At the beginning, I had no idea how to explore the synthesis method, and the ratio of raw materials and reaction conditions needed to be repeatedly considered. However, after unremitting research, I finally got a method that can make the raw materials efficiently converted.
    Monitor the reaction process, and use various instruments to gain insight into the minute changes in molecules. The product is purified and has been tried many times to obtain a pure product.
    Looking at this product now, it is stable in nature and may be useful in the fields of medicine and materials. I will continue to explore and expand its application boundaries, hoping to contribute to the academic community and industry, and promote the research and development of this compound to a new level, for the benefit of the world.
    Toxicity Research
    Fu 4 - Bromol - (Difluoromethoxy) - 2 - Fluorobenzene This substance is crucial for toxicity research. Examine its properties in detail and observe its impact on the organism. Although its shape and color may be normal, the toxicity is hidden and cannot be ignored.
    Study it, observe the way it enters the body, or through breathing, or through skin touch, or diet. After entering the body, it flows through the bloodline, disturbing the internal organs. In the context of experiments, try it with all living things, and see that it may cause damage to the organs, or disrupt the order of physiology.
    And the poison of this substance may be cumulative, and if it is touched for a long time, the harm will be more and more obvious. Therefore, when it is made and used, it is necessary to strictly implement protective methods, so as not to leak and cause harm to living beings. Only by carefully studying it and observing it carefully can we know the depth of its poison, so as to avoid its harm and ensure the safety of the people.
    Future Prospects
    I have studied 4 - Bromol - (Difluoromethoxy) - 2 - Fluorobenzene. Looking at the current state, although it has been achieved, there is still a vast world in the future.
    This substance has potential uses in various fields of chemical industry. Its unique structure and different properties may be used to create new materials and add new energy to industry. The way of medicine may also be the basis for new drugs to treat various diseases.
    Future research should deepen the study of its properties and explore more of its hidden capabilities. Optimize the preparation method to reduce its cost and increase its yield. And seek the extension of its application, so that it can be used in more fields.
    I believe that with time, 4 - Bromol - (Difluoromethoxy) - 2 - Fluorobenzene will be able to shine and show its outstanding effect in the future world, for the well-being of everyone, and for the prosperity of all karma.
    Where to Buy 4-Bromol-(Difluoromethoxy)-2-Fluorobenzene in China?
    As a trusted 4-Bromol-(Difluoromethoxy)-2-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromol-(Difluoromethoxy)-2-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 4-Bromol- (Difluoromethoxy) -2-Fluorobenzene?
    4-Bromo-1- (difluoromethoxy) -2-fluorobenzene, this is an organic chemical. It has multiple uses and is often used as a key intermediate in the field of pharmaceutical synthesis. Due to the unique electronic effect and spatial structure of difluoromethoxy and fluorine atoms, it can endow drugs with better biological activity, membrane permeability and metabolic stability. For example, it may be used to develop new antibacterial and antiviral drugs. Through its structural characteristics, it can precisely act on specific targets of pathogens and improve drug efficacy.
    In the field of materials science, it also has important functions. Due to its fluorine-containing structure, it can improve the properties of materials, such as improving their corrosion resistance, weather resistance and low surface energy. Taking the field of coatings as an example, the addition of this compound may lead to the preparation of special coatings with excellent performance, which are widely used in aerospace, automobile manufacturing and other industries that require strict material properties.
    Furthermore, in the creation of pesticides, 4-bromo-1- (difluoromethoxy) -2-fluorobenzene is also promising. With its unique chemical structure, new pesticides with high efficiency, low toxicity and environmental friendliness can be developed, enhancing the control effect on pests and pathogens while reducing the impact on the environment. In short, this compound has shown broad application prospects in many fields, and its potential uses are expected to be further expanded with the deepening of research.
    What are the physical properties of 4-Bromol- (Difluoromethoxy) -2-Fluorobenzene?
    4-Bromo-1- (difluoromethoxy) -2-fluorobenzene, this is an organic compound. Looking at its physical properties, it is mostly liquid at room temperature and pressure, but the specific state may vary slightly due to factors such as purity.
    It has a certain degree of volatility, but compared with many common organic solvents with low boiling points, the volatility is slightly weaker. Its boiling point is about within a specific range, which is determined by factors such as the intermolecular force of the compound. The existence of bromine, fluorine atoms and difluoromethoxy groups in its molecules makes the intermolecular force present a unique state, which in turn affects the boiling point.
    The density of this compound also has its own characteristics. Compared with water, its density may be greater than that of water, so if mixed with water, it will mostly sink to the bottom. And its solubility is also critical. It may have good solubility in common organic solvents, such as ethanol, ether, dichloromethane, etc., because its molecular structure and organic solvent molecules can form suitable interactions, such as van der Waals force. In water, its molecular polarity matches the polarity of water poorly, so its solubility is poor.
    Furthermore, its appearance may be a colorless to light yellow transparent liquid, and the appearance of this color is related to the atoms and chemical bonds in the molecular structure. The electronic transition characteristics of halogen atoms such as bromine and fluorine in the molecule affect their optical properties, which in turn leads to the appearance of color.
    In addition, the compound has a certain smell, but the description of the smell is difficult to be accurate. Generally, it can be said that it has a special organic halide smell. This smell also stems from the characteristics of halogen atoms and functional groups in the molecular structure. In short, the physical properties of 4-bromo-1- (difluoromethoxy) -2-fluorobenzene are determined by its molecular structure, and are closely related to its physical properties in applications such as organic synthesis.
    What are the chemical properties of 4-Bromol- (Difluoromethoxy) -2-Fluorobenzene?
    4-Bromo-1- (difluoromethoxy) -2-fluorobenzene, this substance is an organic compound, its chemical properties are particularly important, and it is related to many chemical processes and applications.
    Discussing physical properties, under normal temperature and pressure, it may be a colorless to pale yellow liquid with a specific odor. Its boiling point, melting point and density are determined by intermolecular forces and structures. Due to the presence of halogen atoms and methoxy groups in the molecule, its boiling point may be increased due to the increase of relative molecular mass and polarity.
    Chemical activity, the presence of benzene rings endows it with aromaticity, enabling it to participate in electrophilic substitution reactions. The bromine atom acts as a blunt group and an ortho-para-site locator, which makes it easy for electrophilic reagents to attack its ortho-site and para-site. And difluoromethoxy and fluorine atoms also affect the distribution of electron clouds in the benzene ring, changing the activity of the benzene ring.
    Among them, bromine atoms can participate in nucleophilic substitution reactions. When suitable nucleophilic reagents are encountered, bromine ions can be replaced to form new compounds. This property can be used in organic synthesis to construct carbon-heteroatom bonds. The fluorine atom of difluoromethoxy has high electronegativity, which can enhance the polarity of molecules and affect their solubility and reactivity. And difluoromethoxy groups may participate in some special reactions, such as the interaction with metal reagents, to
    The impact of this compound on the environment and organisms also requires attention. Because it contains halogen atoms, it may be toxic and bioaccumulative. Degradation or slow in the environment, so strict regulations must be followed in production, use and disposal to reduce its ecological harm.
    What is the synthesis method of 4-Bromol- (Difluoromethoxy) -2-Fluorobenzene?
    The synthesis method of 4-bromo-1 - (difluoromethoxy) - 2-fluorobenzene can be carried out according to the following steps.
    The first amount of 2-fluoro-4-bromophenol is taken as the starting material, because the desired bromophenol substituent is already available on the benzene of the compound, which is advantageous for the purpose of the molecule. 2-fluoro-4-bromophenol is placed in a reverse container, and the amount of is added, such as carbonate. The action of is to depolarize the phenol group and increase its nucleation.
    And, add difluorobromomethane to the above mixture. Difluorobromomethane is used here as a supplier of difluoromethoxy. In the case of benzene, the deoxidized phenoxy will attack the carbon atom of difluorobromomethane, and the nucleus will be substituted for the inverse. The bromine will be used to remove the group, and the difluoromethoxy group will be introduced on the benzene to generate the target compound 4-bromo-1 - (difluoromethoxy) -2-fluorobenzene.
    The reaction process should be carried out at an appropriate temperature. Generally, the reaction process can be controlled in the added flow to promote the reaction process, so that the reaction material can be fully connected. After the review, it is possible to obtain high-grade 4-bromo-1 - (difluoromethoxy) -2-fluorobenzene by means of extraction, washing, drying, column precipitation, etc.
    What is the price range of 4-Bromol- (Difluoromethoxy) -2-Fluorobenzene in the market?
    4-Bromo-1- (difluoromethoxy) -2-fluorobenzene is on the market, and its price range is difficult to determine. The price of this compound often varies due to many reasons.
    The first to bear the brunt is the difficulty of preparation. If the synthesis method is difficult, rare raw materials, harsh reaction conditions, or multiple steps are required, the cost will be high, and the price will also increase. If the raw materials used are special reagents that are not easily available, or the reaction needs to be carried out under extreme temperatures and pressures, the cost will rise, causing the market price to rise.
    Furthermore, the supply and demand relationship in the market determines its price. If there is a strong demand for this product, such as in the fields of medicine and pesticides, it is a key intermediary, and the supply is limited, the price will rise because demand exceeds supply. On the contrary, if demand is low and supply exceeds demand, the price may fall.
    Repeat, the scale of production also has an impact. In large-scale production, due to the scale effect, the unit production cost may be reduced, but if the production scale is small, the cost per unit will increase, and the price will also be implicated.
    In addition, regional factors cannot be ignored. Prices vary in different places due to differences in transportation costs, tax policies and local market competition. Due to the inconvenience of transportation, transportation costs add to the price of the product; and in places with fierce competition, merchants may adjust the price to compete for the market.
    From this perspective, the market price of 4-bromo-1- (difluoromethoxy) -2-fluorobenzene fluctuates between a few and several hundred yuan per gram, which is difficult to determine an exact range. For details, it is necessary to consult chemical raw material suppliers or check real-time quotations on chemical product trading platforms to get close to the actual price.