4-Bromo-3-Fluoronitrobenzene

Hongda Chemical

Specifications

HS Code	281049
Chemical Formula	C6H3BrFNO2
Molar Mass	220.00 g/mol
Appearance	Yellow to light brown solid
Melting Point	38 - 42 °C
Boiling Point	242 - 244 °C
Density	1.816 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, acetone
Flash Point	100 °C
Purity	Typically high - purity products around 97%+
Cas Number	86077-70-7

As an accredited 4-Bromo-3-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 4 - bromo - 3 - fluoronitrobenzene packaged in a sealed, chemical - resistant bottle.
Storage	4 - bromo - 3 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. It should be kept in a tightly closed container to prevent exposure to air and moisture. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential chemical reactions.
Shipping	4 - bromo - 3 - fluoronitrobenzene is shipped in sealed, corrosion - resistant containers. Special care is taken to ensure proper labeling. It's transported under regulated conditions, avoiding exposure to heat, ignition sources, and incompatible substances.

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General Information

Historical Development

4 - Bromo - 3 - Fluoronitrobenzene is also an organic compound. It is gradually emerging in the field of chemical synthesis. Tracing its origin, it was only the research object of chemists' desks at the beginning, and little known.
In the past, the synthesis of this compound was cumbersome and inefficient. Chemists worked hard to optimize the synthesis method. Over the years, technology has advanced, and new synthesis paths have gradually emerged.
First, the selection and ratio of raw materials need to be carefully considered. At that time, technology was limited, and it was not easy to obtain pure raw materials. Later, with the development of chemical technology, the purity and availability of raw materials have been greatly improved.
During the synthesis process, the control of reaction conditions is also crucial. The choice of temperature, pressure, and catalyst affects the quality and yield of the product with a slight difference. After countless tests, the appropriate reaction conditions have been found.
Up to today, the synthesis technology of 4 - Bromo - 3 - Fluoronitrobenzene has been quite mature, and it has played an important role in many fields such as medicine and materials. It is an important achievement in the development of chemistry.

Product Overview

Today there is a compound called 4 - Bromo - 3 - Fluoronitrobenzene. Its shape is also an organic compound with a unique structure. Looking at its molecular formula, it contains bromine (Bromo), fluorine (Fluoro) and nitro (nitro) groups, arranged in an orderly manner.
This compound is widely used in the field of organic synthesis. It can be used as an intermediate to prepare other fine chemicals. Its reactivity is unique due to the characteristics of each group. Bromine atoms are active and can participate in reactions such as nucleophilic substitution; fluorine atoms have strong electronegativity, which affects the electron cloud distribution of molecules; nitro groups also have a significant effect on the electron density of benzene rings, which in turn affects their chemical behavior.
The preparation of this product requires a fine process and controlled reaction conditions, such as temperature, pressure, catalyst, etc., to obtain satisfactory yield and purity. Therefore, 4-Bromo-3-Fluoronitrobenzene plays an important role in the research and practical application of organic chemistry.

Physical & Chemical Properties

4 - Bromo - 3 - Fluoronitrobenzene is an organic compound. Its physical and chemical properties are unique. Looking at its appearance, it may be in a solid state at room temperature, with a specific crystalline form, and its color may be colorless to light yellow. When it comes to solubility, it has a certain solubility in organic solvents, such as ethanol, ether, etc., but little solubility in water. This is because its molecular structure has a large proportion of hydrophobic groups. Its melting point and boiling point are affected by intermolecular forces, showing corresponding values, which are of great significance for its separation and purification. In terms of chemical properties, the presence of bromine, fluorine and nitro groups on the benzene ring gives it unique reactivity. Nitro groups have strong electron-absorbing properties, which reduce the electron cloud density of the benzene ring and make it more prone to nucleophilic substitution reactions; bromine and fluorine atoms can participate in halogenated hydrocarbon-related reactions, providing a variety of paths for organic synthesis, and are widely used in the field of fine chemicals.

Technical Specifications & Labeling

There are currently chemical products 4 - Bromo - 3 - Fluoronitrobenzene, which should be discussed in detail in terms of their technical specifications and identification (product parameters).
The technical specifications of this product, the first priority is its purity. It must be measured by subtle methods, so that the purity can reach a very high level before it can meet the needs of the user. The impurity content must also be strictly limited to prevent disturbing its performance.
As for the logo, the product parameters should be clear. From the appearance of color, state, to the rationalization of properties, such as melting point, boiling point, etc., should be recorded in the logo. Users will know its characteristics when they look at it, so as not to risk misuse.
To prepare this product, the process must be refined, in accordance with scientific regulations, and in accordance with strict standards, in order to produce a good product, in response to the requirements of all parties and live up to expectations.

Preparation Method

In order to prepare 4 - Bromo - 3 - Fluoronitrobenzene, the method is as follows:
In terms of raw materials, select suitable halogenated aromatics, supplemented by reagents containing bromine, fluorine and nitro groups. In the synthesis process, a specific halogenating agent is first used to bromide aromatics under appropriate reaction conditions, and the brominated product is obtained under precise temperature control.
Then, fluorine atoms are introduced, and the reaction steps are cleverly designed to achieve fluorination by means of nucleophilic substitution or other suitable reaction paths. This step requires strict selection of solvents and catalysts to ensure a smooth reaction.
The introduction of nitro groups is also critical. The use of nitrifying reagents follows the established reaction procedures.
The monitoring of each step of the reaction is essential, and the reaction process and product purity are clearly observed by means of chromatography, spectroscopy and other analytical methods. In the post-treatment stage, high purity 4-Bromo-3-Fluoronitrobenzene is obtained through purification steps such as extraction, distillation, and recrystallization. The whole process is based on chemical principles, and each link is finely regulated to achieve the purpose of efficient preparation.

Chemical Reactions & Modifications

4-Bromo-3-fluoronitrobenzene is also an important compound in organic chemistry. Its chemical reaction is related to chemical transformation and performance changes, and is of great importance to our chemical researchers.
In the past, the method of synthesizing this compound was cumbersome and the yield was not ideal. However, today is different from the past, with advanced chemical technology, and new reaction paths are gradually emerging.
After repeated experiments, we found that the synthesis of nitrobenzene derivatives can be optimized by reacting with a specific halogenating agent. The reaction conditions are mild and the yield is significantly improved.
As for performance, the structure of 4-bromo-3-fluoronitrophenylbenzene bromide, fluorine and nitro groups has unique chemical activity. It can be used as a key intermediate in many organic reactions, and a variety of functional compounds can be derived, which is promising in the fields of medicine and materials.
In the future, when continued exploration, it is hoped to explore more potential reactions, optimize performance, and contribute to the development of chemistry and the progress of industry.

Synonyms & Product Names

4 - Bromo - 3 - Fluoronitrobenzene, this substance is an important material for chemical research. Its aliases are many, due to differences in chemical naming rules and application scenarios.
From the structural analysis, bromine (Bromo), fluorine (Fluoro) and nitro (nitro) are arranged at specific positions in the benzene ring, resulting in its unique chemical activity. In the industry, or according to its characteristics, it is called "halogenated nitrobenzene derivatives". In some synthetic processes, it is also regarded as "key halogenated aromatic nitro intermediates" because of its key role.
When in commercial circulation, in order to facilitate identification and trading, different manufacturers may have unique trade names. For example, "Youchuang-Bromofluoronitrobenzene" emphasizes high quality; or "Suda-4-Bromo-3-fluoronitrobenzene", suggesting efficient supply. Many aliases and trade names are used to accurately describe this product, which is beneficial to chemical research and industrial applications.

Safety & Operational Standards

4-Bromo-3-fluoronitrobenzene is also a chemical product. Its safety and operating specifications should be detailed.
Where this material is involved, safety is the first priority. Its nature may be harmful, and it can be harmful to the body if touched, smelled, or eaten. Therefore, when handling, protective equipment is essential, such as gloves, masks, goggles, etc., to prevent the skin, eyes, and respiratory tract from being invaded.
In the operation room, ventilation must be good, so that harmful gas can be dissipated and avoid accumulation and danger. Place objects in a dry, cool, protected from fire and heat, and keep them classified. Do not mix with other objects to prevent their reactions from changing.
When operating, the procedures must be followed. Weighing is accurate, and the utensils are clean and suitable. The temperature, time, and amount of agent of the reaction are all according to the recipe, and cannot be changed. Stir well, control the temperature steadily, and adjust it in a timely manner.
If there is a spill, deal with it as soon as possible. Small leaks can be collected with adsorbed materials, and hazardous waste devices can be placed; large leaks should be cleared first, and then dealt with according to the policy, to ensure the environment and human safety.
After use, clean the utensils and grounds, and dispose of the rest according to the regulations. The records of all things involved in this matter are detailed and accurate, so as to be ready for investigation.
In short, the safety and operating standards of 4-bromo-3-fluoronitrobenzene are related to human beings and the environment, and must be followed carefully and cannot be slack.

Application Area

4 - Bromo - 3 - Fluoronitrobenzene is an important raw material for organic synthesis. Its application field is quite wide. In the field of medicinal chemistry, this compound can be prepared with specific pharmacological activities through multiple steps of delicate reactions, or as a key intermediate to help the development of new drugs to cure various diseases.
In the field of materials science, with its unique chemical structure, it can participate in the synthesis of polymer materials. By carefully designing the reaction path, it can be introduced into the main chain or side chain of the polymer to impart special optical and electrical properties to the material, which can be used to manufacture advanced optoelectronic materials.
In pesticide chemistry, this compound can be modified and converted into highly efficient, low toxic and environmentally friendly pesticide components. Through its interaction with specific targets in vivo, precision insecticides, weeding and other effects are achieved to ensure agricultural harvests.
In summary, 4 - Bromo - 3 - Fluoronitrobenzene has key value in many application fields and is of great significance to promote the development of related industries.

Research & Development

In recent years, I have dedicated myself to the study of 4 - Bromo - 3 - Fluoronitrobenzene in the field of chemistry. Its characteristics are unique, and it is quite useful in organic synthesis.
At the beginning, I explored the method of its preparation, tried many times, but encountered all kinds of obstacles. The selection of raw materials and the conditions of reaction all need to be carefully weighed. After months of research, a feasible method was finally obtained, and the yield gradually became considerable.
Then, consider its application. In the field of pharmaceutical synthesis, it can be used as a key intermediate, providing an opportunity for the creation of new agents. In materials science, it is also expected to contribute to the research and development of new materials.
However, the road to research and development is not smooth. Faced with cost constraints and environmental considerations, we need to deal with them cautiously. I will make unremitting efforts to expand its application, promote the development of this product, and contribute to the progress of chemistry.

Toxicity Research

Toxicity study of 4-bromo-3-fluoronitrobenzene
Recently, in the field of chemical research in China, it is very important to investigate the toxicity of 4-bromo-3-fluoronitrobenzene. This compound has its unique appearance, but its potential toxicity cannot be underestimated.
After a series of experiments, its impact on organisms has gradually emerged. At the cellular level, it can cause changes in cell activity, affecting the normal metabolism and proliferation of cells. In animal experiments, many abnormalities are also seen, such as abnormal organ function.
Investigate its toxicity mechanism, or due to the synergistic effect of bromine, fluorine and nitro groups in the structure. The halogen properties of bromine and fluorine, coupled with the strong electron-absorbing properties of nitro groups, make the compound easy to interact with biological macromolecules and interfere with biochemical reactions in vivo.
Although current research has been obtained, in order to fully understand its toxicity, further investigation is still needed. In the future, more subtle methods should be used to expand the breadth and depth of research, so as to clarify its potential harm to ecology and human health, and provide a solid basis for protection and application.

Future Prospects

Wuguan 4 - Bromo - 3 - Fluoronitrobenzene This product has extraordinary potential and is related to the future development. It is expected to shine in the chemical industry, such as the rise of a new star. Although it is only emerging at the moment, it has great prospects.
In the future, or in the process of fine chemistry, it will be a key raw material and help many new materials come into being. It may also play an important role in the field of pharmaceutical research and development, providing new opportunities to overcome difficult diseases. Its unique chemical structure gives it infinite possibilities.
We should study it carefully, explore its mysteries, and pioneer and innovate. With time, we will be able to unearth its greatest value, bring a new situation to the industry, and achieve a brilliant cause. This is our vision for the future.

Where to Buy 4-Bromo-3-Fluoronitrobenzene in China?

As a trusted 4-Bromo-3-Fluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 4-Bromo-3-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Bromo-3-Fluoronitrobenzene?

4-Bromo-3-fluoronitrobenzene, which has a wide range of uses. In the field of organic synthesis, it is often a key intermediate.
First, it can be used to create medicine. The presence of halogen atoms and nitro groups on the phenyl ring gives it unique reactivity, which can be used to construct molecular structures with specific biological activities through various chemical reactions, thus paving the way for the development of new drugs. For example, nucleophilic substitution reactions can be used to introduce various groups containing nitrogen, oxygen and other heteroatoms to meet the needs of specific targets and help the development of anti-cancer, anti-infection and other drugs.
Second, it has also made contributions in the field of materials science. It can be used to participate in polymerization reactions to introduce special functional groups into polymer materials to improve material properties. For example, it can improve the thermal stability and optical properties of materials, and play a role in the preparation of high-performance polymer films, optoelectronic materials, etc.
Third, it is also indispensable in the synthesis of pesticides. Its structure can be modified to derive compounds that have high poisoning or inhibitory effects on pests, providing a basis for the development of green and high-efficiency pesticides. By precisely designing the molecular structure, the targeting and environmental friendliness of pesticides can be improved. In conclusion, 4-bromo-3-fluoronitrobenzene, with its unique structure and reactivity, plays an important role in many fields such as medicine, materials, and pesticides, and contributes to the innovation and development of various fields.

What are the physical properties of 4-Bromo-3-Fluoronitrobenzene?

4-Bromo-3-fluoronitrobenzene is one of the organic compounds. It has unique physical properties, so let me tell you one by one.
Looking at its appearance, at room temperature, it is mostly a light yellow to light brown crystalline powder with fine and uniform texture. This state is easy to observe and operate, and is also a characterization of its physical properties.
Talking about the melting point, it is between 44 ° C and 48 ° C. The melting point is one of the characteristics of matter. This temperature range allows 4-bromo-3-fluoronitrobenzene to undergo solid and liquid transformation under specific conditions. When the outside temperature rises near the melting point, its lattice structure gradually loosens, and the intermolecular forces change, so it melts from a solid state to a liquid state.
In terms of boiling point, it is roughly around 263 ° C. The level of boiling point is related to the transformation of the substance between gaseous and liquid states. At this temperature, the molecular kinetic energy is sufficient to overcome the surface tension of the liquid and the attractive force between molecules, so that it can boil and gasify.
4-Bromo-3-fluoronitrobenzene has a density of about 1.834g/cm ³. The density reflects its mass per unit volume, which indicates that it has a higher density than common substances. In practical applications, density affects the sink, float and mixing ratio of substances.
Solubility is also an important physical property. It is insoluble in water because water is a polar solvent, while 4-bromo-3-fluoronitrobenzene has a relatively weak molecular polarity. According to the principle of similarity and miscibility, the two are not easily miscible. However, it is soluble in organic solvents such as ethanol, ether, and dichloromethane. The molecular structure of such organic solvents is more compatible with 4-bromo-3-fluoronitrobenzene, and intermolecular forces can promote their mutual dissolution. This property is of great significance in the fields of organic synthesis, separation and purification.
In summary, the physical properties of 4-bromo-3-fluoronitrobenzene, from appearance, melting point, boiling point, density to solubility, are all key considerations in chemical research and industrial applications, laying the foundation for its rational use and in-depth exploration.

What are 4-Bromo-3-Fluoronitrobenzene synthesis methods?

The synthesis method of 4-bromo-3-fluoronitrobenzene is described in detail below.
First, 3-fluoronitrobenzene can be initiated by halogenation reaction. This reaction requires a suitable halogenating agent, such as a brominating agent. Usually, under appropriate reaction conditions, such as suitable temperature, solvent and catalyst, bromine atoms can be selectively introduced to specific positions of 3-fluoronitrobenzene to obtain 4-bromo-3-fluoronitrobenzene. Among these, the choice of solvent is crucial, which needs to be able to dissolve the reactants without adversely affecting the reaction process. The catalyst can also effectively promote the progress of the reaction, increasing the reaction rate and yield.
Second, it can also be achieved by nitrification from 4-bromofluorobenzene. In this process, a suitable nitrifying reagent needs to be used, and the nitro group should be introduced to the specific check point of 4-bromofluorobenzene in a suitable reaction environment to obtain the target product. Reaction temperature, proportion of reactants and other factors have a significant impact on the reaction result. If the temperature is too high, it may cause more side reactions, affecting the purity and yield of the product; and the proportion of reactants is inappropriate, which will also prevent the reaction from being fully carried out.
Furthermore, the synthesis of 4-bromo-3-fluoronitrobenzene can be achieved through other more complex organic synthesis pathways, such as through multi-step reactions to gradually build molecular structures. Although these methods have many steps, they can sometimes improve the purity and selectivity of the product to meet specific synthesis needs. However, their operation is more cumbersome, and the control requirements for reaction conditions are more stringent.
In short, there are various methods for synthesizing 4-bromo-3-fluoronitrobenzene, each with advantages and disadvantages. In practical applications, appropriate synthesis methods need to be carefully selected according to specific experimental conditions, product requirements and other factors.

4-Bromo-3-Fluoronitrobenzene What are the precautions during storage and transportation?

4-Bromo-3-fluoronitrobenzene is an important raw material for organic synthesis. When storing and transporting, you must be careful and pay attention to many matters.
One is related to storage. This substance has a certain chemical activity and should be stored in a cool, dry and well-ventilated place. Avoid open flames and hot topics to prevent danger. Because it is more sensitive to heat, it is easy to decompose or cause other adverse reactions when heated. The temperature of the storage should be controlled within a specific range to avoid excessive temperature causing it to deteriorate. And it must be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed to prevent violent chemical reactions.
Second, when transporting, there are also many key points. Before transportation, make sure that the packaging is complete and well sealed to prevent leakage. The transportation tools used must be clean, dry and free of other residual chemicals to avoid reaction with it. During transportation, the traffic should be stable to avoid bumps and vibrations to prevent material leakage due to damaged packaging. At the same time, transporters should be familiar with the characteristics of this substance and emergency treatment methods, and can respond quickly in case of emergencies.
Furthermore, whether it is storage or transportation, it is necessary to strictly follow relevant safety regulations and standards. Regular inspection and maintenance of storage facilities and transportation tools to ensure that they are in good condition. And make detailed records, such as storage time, quantity, transportation route, etc., for traceability and management. In this way, the safety of 4-bromo-3-fluoronitrobenzene during storage and transportation is guaranteed.

What is the market price range for 4-Bromo-3-Fluoronitrobenzene?

The market price range of 4-bromo-3-fluoronitrobenzene is difficult to say exactly. This is subject to many factors due to changing market conditions.
From the perspective of raw materials, if the bromide, fluoride and nitrobenzene raw materials required for the synthesis of this compound are abundant and stable, the cost of 4-bromo-3-fluoronitrobenzene may be controllable, and the price will also stabilize. However, if raw materials are scarce, prices will rise, causing the price of finished products to rise.
The production process is also the key. Advanced and efficient processes can reduce energy consumption, yield, and production costs, and have an advantage in market pricing. If the process is backward, the cost is high, and the price is not low.
The situation of market supply and demand has a profound impact on prices. If many industries, such as medicine, pesticides, materials, etc., have strong demand for 4-bromo-3-fluoronitrobenzene, but output is limited and supply exceeds demand, prices will soar. On the contrary, if demand is weak and supply is excessive, prices will inevitably fall.
In addition, geographical differences, trade policies, logistics costs, etc. are all related to prices. Different places may have different selling prices due to differences in economic levels and tax policies. Trade policies are tight, which affects import and export costs and affects prices. The level of logistics costs also makes the price of products reaching customers different.
In summary, the market price range of 4-bromo-3-fluoronitrobenzene fluctuates unpredictably. To know the exact price, it is necessary to gain real-time insight into the raw material market, production process progress, supply and demand situation, and related policy changes.