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4-Bromo-3-Chlorofluorobenzene

4-Bromo-3-Chlorofluorobenzene

Hongda Chemical

Specifications

HS Code

960428

Chemical Formula C6H3BrClF
Molecular Weight 225.44
Appearance Colorless to light yellow liquid
Boiling Point Approximately 190 - 192 °C
Density Around 1.82 - 1.86 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Odor Characteristic aromatic odor

As an accredited 4-Bromo-3-Chlorofluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - bromo - 3 - chlorofluorobenzene packaged in a sealed glass bottle.
Storage 4 - bromo - 3 - chlorofluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent vapor leakage. Due to its potential toxicity and flammability risks, it should be isolated from incompatible substances and stored in accordance with local safety regulations.
Shipping 4 - bromo - 3 - chlorofluorobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling and secure packaging to prevent leakage during transit.
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4-Bromo-3-Chlorofluorobenzene 4-Bromo-3-Chlorofluorobenzene
General Information
Historical Development
Those who have heard of chemical things include 4 - Bromo - 3 - Chlorofluorobenzene. The beginning of the thing is really related to the process of research in the past. At the beginning, the sages worked hard in the field of chemistry, hoping to understand the properties of substances and the method of systematization.
At that time, the art of chemistry was not as sophisticated as it is today, and the researchers with perseverance, through countless trials and errors, gradually touched its barriers. In the category of halogenated aromatics, in order to obtain this 4 - Bromo - 3 - Chlorofluorobenzene, many problems need to be solved, such as the conditions of the reaction and the ratio of raw materials.
As the years go by, researchers continue to improve the process and optimize the material to achieve its formation. Either adjust the temperature or change the pressure, and after years of work, this product can be prepared more stably. Its use in the field of organic synthesis has gradually become apparent, paving a new way for subsequent research and various chemical reactions, and becoming an indispensable part of the long volume of chemical development.
Product Overview
4-Bromo-3-chlorofluorobenzene is an organic compound. Its color is pure and stable, and it has the properties of halogenated aromatics.
Looking at its structure, on the benzene ring, there is one atom of bromine, chlorine, and fluorotrihalogen. For bromine, the atomic weight is large, which slightly increases the polarity of the molecule; chlorine and fluorine also develop their own properties, affecting the reactivity and physical characteristics of the molecule.
When preparing, bromine, chlorine, and fluorine atoms are often introduced in sequence based on benzene. The reaction conditions must be precisely controlled to obtain high-purity products.
It has a wide range of uses and is a key intermediate in the field of pharmaceutical synthesis, which can assist in the creation of specific drugs. In materials science, it can also optimize material properties.
4-Bromo-3-chlorofluorobenzene, although microscopic, plays a crucial role in the field of chemistry and is an important role in scientific research and industry.
Physical & Chemical Properties
4 - Bromo - 3 - Chlorofluorobenzene is an organic compound, and its physicochemical properties are very important. Looking at its physical properties, at room temperature and pressure, this substance may be in a liquid state, with a specific boiling point and melting point. The boiling point is related to the temperature required for its gasification, and the melting point is the critical temperature for solid to liquid state. Its density is also a key parameter, which affects its floating, sinking and mixing characteristics in different media.
Discussing chemical properties, the presence of bromine, chlorine and fluorine atoms in this compound gives it unique reactivity. The electronic effect of halogen atoms can affect the density distribution of electron clouds on the benzene ring, making it prone to electrophilic substitution reactions. For example, under suitable catalyst and reaction conditions, it can be substituted with electrophilic reagents to generate various derivatives and expand its application in the field of organic synthesis. The physicochemical properties of this compound lay the foundation for its potential applications in materials science, medicinal chemistry and many other fields.
Technical Specifications & Labeling
Today there is a product called 4 - Bromo - 3 - Chlorofluorobenzene. The process specifications and identification (product parameters) of its production are related to the quality and use of this product, and cannot be ignored.
The production of this product should also follow the strict method. The choice of raw materials must be pure and good, the proportion must be prepared, and it must be accurate. The temperature and time of the reaction are also important. If the temperature is high, the quality will be changeable, and if the time is short, it should not be complete. The utensils used in the meantime must be clean and suitable, and the integrity should be prevented from being mixed and damaged.
As for the identification (product parameters), its composition, purity and characteristics should be clearly stated. The composition is detailed, and people can know its chemical structure; the purity is apparent in the number to prove its quality; the characteristics indicate its shape and color, such as the solid-liquid of the state, and the depth of color. In this way, the user can use it according to its details, and do not make mistakes. Process specifications and labels (product parameters), in the production and use of 4-Bromo-3-Chlorofluorobenzene, are the essence and should not be ignored.
Preparation Method
4 - Bromo - 3 - Chlorofluorobenzene is an important compound in organic synthesis, and its preparation requires exquisite methods.
The selection of raw materials is crucial, and specific halogenated aromatics are often used as the starting point. For example, benzene derivatives with appropriate substituents can be selected, and such raw materials are available from many chemical reagent suppliers.
The preparation process is as follows: First, bromine and chlorine atoms are introduced in a halogenation reaction. In this step, the reaction conditions, such as temperature, reaction time, and the proportion of reactants, need to be precisely controlled. Usually, the reaction with a specific halogenation reagent in a suitable solvent can ensure the precise positioning of halogen atoms.
Subsequent reaction steps also need to be carefully operated. After the reaction is completed, the product needs to be purified to remove impurities. This process is often used by distillation, extraction or column chromatography.
In terms of catalytic mechanism, specific catalysts can accelerate the reaction process and increase the yield. Select the appropriate catalyst, depending on the reaction characteristics, such as some metal catalysts have good catalytic effect in halogenation reactions. By carefully controlling the above raw materials, processes, reaction steps and catalytic mechanisms, high purity 4-Bromo-3-Chlorofluorobenzene can be obtained.
Chemical Reactions & Modifications
In today's world, in the field of chemistry, there is a name called 4-Bromo-3-Chlorofluorobenzene, and the study of its chemical reaction and modification is quite crucial.
Looking at the reaction, all kinds of conditions are deeply affected. If the temperature rises, the reaction rate may increase, but if it is too high, side reactions will occur, and the product will be impure. The same is true for pressure, which can promote the reaction to proceed, but if it is not suitable, it will hinder it. And catalysts, like the magic key, can lower the reaction barrier, speed up the process, and make the reaction efficient.
As for modification, chemists are exhausted. After modifying the structure, its stability may be increased, so that it can survive in complex environments. Or change its activity, so that it can quickly react with other substances and expand its use. With the wonderful method of chemistry, 4-Bromo-3-Chlorofluorobenzene can be rejuvenated, and it can shine in the pharmaceutical and material industries, contributing to the progress of the world.
Synonyms & Product Names
4 - Bromo - 3 - Chlorofluorobenzene This thing, its synonymous name and the name of the commodity are quite crucial. In the study of Fu Gu, the name of the thing must be investigated in detail. This compound, or another name, is due to the research of scholars and regional differences, resulting in its different names but the same.
Or Yunqi is a variant of "bromochlorofluorobenzene", which is precisely named according to the order and number of its atoms. However, among businesses, it is well known and remembered, and it also has a simple name. If it is named for its characteristics, it is called practical, so that the industry can know what it is.
And the academic exchange of husband, the name is correct and smooth. Although its scientific name is rigorous, it is also called popular in daily discussions. Therefore, the name of synonyms and the name of commodities run parallel in the world and complement each other. They are shared by the academic and business circles. They are all indispensable for understanding the nature of this thing and the use of this thing.
Safety & Operational Standards
4 - Bromo - 3 - Chlorofluorobenzene Safety Production and Operation Specifications
Husband 4 - Bromo - 3 - Chlorofluorobenzene is also a chemical product. Its safety production and operation specifications are related to the safety of workers, and it is also a smooth production. It cannot be ignored.
#1. Storage Rules
This product should be stored in a cool, dry and well-ventilated place. Avoid open flames, hot topics, and keep away from fires. Its container must be sealed to prevent leakage. If placed in the open air, or near a heat source, it may cause danger. And it should be stored separately with oxidants, alkalis, etc., and must not be mixed to prevent chemical reactions from occurring and causing disasters.
#Second, the model of operation
The operator must receive professional training and be familiar with the operation process. When operating, wear protective gloves and goggles in front of suitable protective clothing. If the skin or eyes come into contact, rinse with plenty of water urgently, and seek medical attention if necessary. The operation room needs to be well ventilated to prevent gas accumulation. When taking it, it should be handled with care to avoid damage to the container and leakage of materials.
#3. Emergency measures
In the event of a leak, the first thing to do is to evacuate the surrounding people and prohibit the fire. Emergency responders must wear protective equipment to prevent the spread of leaks. Small leaks can be absorbed by inert materials such as sand and vermiculite. A large number of leaks need to be embanketed and contained, and then properly disposed of.
In short, in the production and operation of 4 - Bromo - 3 - Chlorofluorobenzene, it is necessary to strictly abide by safety and operating standards to prevent problems before they occur, so as to ensure safe production and the safety of people and money.
Application Area
4-Bromo-3-chlorofluorobenzene is also an organic compound. Its application field is quite extensive. In the field of pharmaceutical synthesis, it is often an important intermediate. Based on this substance, a variety of specific drugs can be prepared to treat various diseases.
In the field of materials science, it is also important. Or can be used to develop new functional materials, such as photoelectric materials. With its special chemical structure, the material has unique properties, such as good electrical conductivity and optical properties.
In addition, in the field of agricultural chemistry, it may be able to participate in the synthesis of efficient pesticides. Through ingenious design and reaction, pesticides have stronger insecticidal and bactericidal effects, and have less impact on the environment, so as to achieve sustainable development of agriculture. From this point of view, 4-bromo-3-chlorofluorobenzene has value that cannot be ignored in many application fields.
Research & Development
Taste the industry of chemical industry and delve into the road of research, all for the sake of innovation and innovation, so as to benefit the world. Today there is 4 - Bromo - 3 - Chlorofluorobenzene, and the way of its research and use, my heart is always on it.
Begin to explore its properties, analyze its structure, and understand its reaction rules. In the laboratory, try all kinds of things, observe its response to various things, observe the appearance of changes, and record the details of the data. Hope to get precise results, clarify its characteristics, and lay the foundation for subsequent use.
Then think about its development and seek its innovation. Or it can be used in medicine to help treat various diseases; or it can be applied to materials to increase its performance. Although the road ahead is long, but the heart desires, unremitting search. Hope can use the power of science and technology to promote the progress of this thing, so that it can show extraordinary ability in the world, seek well-being for everyone, and leave a solid mark on the road of research and development, living up to my generation's desire to study.
Toxicity Research
Study on the toxicity of 4-bromo-3-chlorofluorobenzene
The toxicity of 4-bromo-3-chlorofluorobenzene is related to the health of living beings and the safety of the environment.
After various experiments, white mice were tested and fed with food containing this substance. Soon, the behavior of white mice was different from usual, hyperactive and impatient, and the desire to eat was also reduced. Looking at it, the organs were damaged, the liver was discolored and different, and the function of the kidneys was also disordered.
It was also tested in plants and planted in the soil containing this substance. Plants grow slowly, the leaves gradually wilt yellow, the flowering period is late and the number of flowers is thin. Obviously, this substance is harmful to both animals and plants.
Furthermore, analyze the dispersion of this substance in the environment. It is difficult to decompose in water and soil, and if it accumulates for a long time, it will sewage the soil, causing harm to the surrounding ecology. And it is easy to volatilize in gas. If people absorb it, it will damage the respiratory system and harm the lungs.
To sum up, 4-bromo-3-chlorofluorobenzene is notoriously toxic, and it is a serious hazard to both ecology and human beings. It is urgent to study its detoxification methods and control its emissions.
Future Prospects
4 - Bromo - 3 - Chlorofluorobenzene is also a new product of chemistry. Looking at this object today, although it is currently in the process of research, its future development can still be expected.
This object has special properties, and it is expected to shine in all fields of chemistry. Or it can be used in the system of new materials, with its unique properties, imparting new energy to the material, so that the material can be used in various aspects such as toughness and corrosion resistance, and it will benefit. In the field of medicine, it may also be possible. With the beauty of its structure, develop new agents to treat all kinds of diseases and save the suffering of the people.
Furthermore, in the process of research, if we can make good use of the benefits of technology and explore its essence, we will definitely be able to expand its application domain. Although there may be thorns in the road ahead, those who study in our generation will have a strong heart and investigate its secrets. I believe that in the near future, 4 - Bromo - 3 - Chlorofluorobenzene will be able to show its great power in the world, for the benefit of all, and the bright pearl of Chenghua World.
Where to Buy 4-Bromo-3-Chlorofluorobenzene in China?
As a trusted 4-Bromo-3-Chlorofluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Bromo-3-Chlorofluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 4-Bromo-3-Chlorofluorobenzene?
4-Bromo-3-chlorofluorobenzene is also an organic compound. Its molecule contains bromine, chlorine and fluorine halogen atoms, and this structure endows it with unique chemical properties.
In terms of reactivity, the benzene ring is aromatic and relatively stable. However, due to the electronegativity and induction effects of bromine, chlorine and fluorine, the electron cloud density of the benzene ring can be changed. Halogen atoms have different electron-absorbing abilities. Fluorine has strong electron-absorbing properties, resulting in a decrease in the electron cloud density of the benzene ring and a decrease in reactivity. However, in the electrophilic substitution reaction, although the activity decreases, the substituent still tends to enter its adjacent and para-sites due to the localization effect of fluorine.
Bromine and chlorine also Bromine and chlorine are ortho and para-sites, which can guide new substituents into their ortho and para-sites in electrophilic substitution reactions. However, the electron-absorbing induction effect of bromine and chlorine also decreases the electron cloud density of the benzene ring slightly. The coexistence of the three makes the reactivity of 4-bromo-3-chlorofluorobenzene lower than that of benzene, and the localization law of electrophilic substitution reactions is complicated.
In nucleophilic substitution reactions, because halogen atoms can leave, under appropriate conditions, such as strong bases, high temperatures or catalysis, bromine, chlorine and fluorine atoms can be replaced by nucleophilic reagents. Bromine has a stronger ability to leave than chlorine and fluorine, so bromine atoms are more likely to be replaced.
It participates in organic synthesis reactions, and can construct a variety of complex organic molecular structures through electrophilic substitution, nucleophilic substitution, and metal catalytic coupling reactions. It is widely used in the fields of medicine, pesticides, materials, etc. It can be used as an intermediate to prepare specific biological activities or functional compounds.
What are the main uses of 4-Bromo-3-Chlorofluorobenzene?
4-Bromo-3-chlorofluorobenzene is a crucial compound in the field of organic synthesis. It has a wide range of uses and is wonderful.
In the field of medicinal chemistry, 4-bromo-3-chlorofluorobenzene is a key intermediate. Through exquisite chemical reactions, it can be converted into specific drug molecules. For example, in the creation of some antibacterial drugs, this compound has exerted its unique effect, helping to construct molecular structures with precise antibacterial activity, making great contributions to human resistance to the invasion of pathogens.
In the field of materials science, 4-bromo-3-chlorofluorobenzene also has extraordinary performance. After a specific process, it can be integrated into the synthesis process of polymer materials. The resulting material, or with unique optical and electrical properties, can be applied to advanced electronic display devices, optical fibers and other fields, contributing to the innovation and upgrading of materials.
Furthermore, in the field of pesticide chemistry, this compound also plays an important role. Based on it, high-efficiency and low-toxicity pesticide products can be developed. With its special chemical structure, it exhibits excellent ability to inhibit and kill specific pests or weeds, contributing to the sustainable development of agriculture and ensuring the harvest of crops.
To sum up, 4-bromo-3-chlorofluorobenzene occupies an important position in many fields such as medicine, materials, pesticides, etc. It is like a magical key that opens the door to many scientific and technological development, and has a profound impact on the progress and development of human society.
What are 4-Bromo-3-Chlorofluorobenzene synthesis methods?
The synthesis method of 4-bromo-3-chlorofluorobenzene is often related to the technology of organic synthesis. There are many methods, and each has its own ingenuity, which is described in detail below.
First, it is based on halogenation reaction. First, take the appropriate benzene derivative and treat it with a specific halogenating agent. If the derivative of benzene is selected, the bromine atom can be selectively connected to a specific position in the benzene ring through the action of a brominating agent. Commonly used brominating agents, such as bromine, are combined with appropriate catalysts. The catalyst can be iron powder or iron tribromide. The two cooperate to induce bromine atoms to the benzene ring to form a bromine-containing intermediate. After that, the intermediate is treated with a chlorinating agent. Commonly used chlorinating agents such as chlorine gas can also connect chlorine atoms to the benzene ring under suitable reaction conditions, such as controlling temperature, pressure and reaction time, to obtain 4-bromo-3-chlorofluorobenzene. The beauty of this method lies in the step-by-step halogenation, which can better control the position of the substituent. However, the reaction conditions are strict and need to be carefully regulated, otherwise it is prone to side reactions.
Second, take the nucleophilic substitution reaction as the path. Select benzene derivatives containing suitable leaving groups as the starting material. If the starting material contains suitable leaving groups, such as sulfonate groups or halogen atoms, it can react with fluorine sources in the presence of nucleophiles. The fluorine source can be selected from potassium fluoride, etc., and the nucleophilic reagent depends on the situation. During the reaction, the nucleophilic reagent helps fluorine ions to attack the benzene ring and replaces the leaving group. The fluorine-containing intermediate is obtained first. Subsequently, bromine and chlorine atoms are introduced by halogenation reaction. The advantage of this approach is that the nucleophilic substitution step has good selectivity for the introduction of fluorine atoms, but the preparation of the starting material may be more complicated, and the connection between each step of the reaction needs to be properly planned.
Third, the reaction is catalyzed by transition metals. Transition metal catalysts such as palladium and nickel can be used to catalyze the cross-coupling reaction between halogenated aromatics. Halogenated aromatics containing bromine and chlorine and halogenated aromatics containing fluorine are used as raw materials. Under the combined action of transition metal catalysts, ligands and bases, cross-coupling occurs. The ligand can adjust the electron cloud density and steric resistance of transition metals, and the base participates in the reaction process. The advantage of this method is that it can efficiently construct carbon-halogen bonds and improve the yield and selectivity of the target product. However, the cost of transition metal catalysts is higher, and the post-reaction treatment may be cumbersome, so the separation and recovery of catalysts need to be considered.
4-Bromo-3-Chlorofluorobenzene what are the precautions during storage and transportation?
4-Bromo-3-chlorofluorobenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First words storage, this compound should be placed in a cool, dry and well-ventilated place. Cover because of its certain chemical activity, high temperature, humid environment is prone to deterioration, or cause chemical reactions. And must be kept away from fire and heat sources to prevent the risk of fire. If it is heated, it may decompose and release harmful gases, endangering safety.
Furthermore, when storing, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed. Due to the chemical properties of this compound, contact with various such substances can easily cause chemical reactions, or cause serious consequences such as explosion and combustion.
As for transportation, it is necessary to ensure that the packaging is complete and sealed. During transportation, it should be properly fixed to prevent damage and leakage of the container. Transportation vehicles should also be equipped with corresponding types and quantities of fire equipment and leakage emergency treatment equipment. If a leak occurs during transportation, the disposal personnel must wear gas masks and protective clothing, and do not let the leak come into direct contact with the human body.
And the planning of transportation routes should avoid sensitive areas such as water source protection areas and densely populated areas. Transport in accordance with relevant regulations and standards to ensure safety, so that 4-bromo-3-chlorofluorobenzene does not cause safety and environmental problems during storage and transportation.
What are the effects of 4-Bromo-3-Chlorofluorobenzene on the environment and human health?
4-Bromo-3-chlorofluorobenzene is one of the organic compounds. Its impact on the environment and human health is of great concern to the world.
At the environmental level, if this compound is released into nature, its behavior and impact are very complex. The first to bear the brunt, it may not linger in soil and water bodies, because its chemical structure is relatively stable, it is difficult to be rapidly degraded by natural forces. And because of its fat-soluble characteristics, it is easily ingested by organisms and accumulates layer by layer in the food chain, posing a threat to many organisms. For example, if aquatic organisms are exposed to it for a long time, or cause physiological disorders, growth and reproduction will be affected by it. The same is true for terrestrial organisms, which may affect the normal growth and development of plants and damage the balance and stability of the ecosystem.
As for human health, its harm cannot be ignored. If people ingest this compound through breathing, diet or skin contact, it may cause a variety of health problems. As far as the respiratory system is concerned, it may irritate the respiratory tract, causing cough, asthma and other diseases, and in the long run, it may damage lung function. In the nervous system, it may interfere with nerve conduction, causing headaches, dizziness, fatigue, and even affecting cognitive and memory functions. Furthermore, its potential carcinogenicity cannot be ignored. Although the specific mechanism is not fully understood, numerous studies have revealed its association with the occurrence of specific cancers.
In summary, 4-bromo-3-chlorofluorobenzene poses latent risks to the environment and human health, so its production, use and release should be strictly controlled to avoid unbearable ecological and human consequences.