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4-Bromo-3,5-Difluorobenzenesulfonylchloride

4-Bromo-3,5-Difluorobenzenesulfonylchloride

Hongda Chemical

Specifications

HS Code

724637

Name 4-Bromo-3,5-Difluorobenzenesulfonylchloride
Molecular Formula C6H2BrClF2O2S
Molecular Weight 307.497 g/mol
Appearance Typically a solid, color may vary (usually white to off - white)
Solubility Soluble in many organic solvents like dichloromethane, chloroform, less soluble in water
Purity Can be obtained in high purity (e.g., 95%+ in commercial products)
Reactivity Highly reactive towards nucleophiles such as amines, alcohols
Hazard Corrosive, can cause skin and eye burns, harmful if inhaled or ingested

As an accredited 4-Bromo-3,5-Difluorobenzenesulfonylchloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 4 - bromo - 3,5 - difluorobenzenesulfonyl chloride packaged in a sealed glass bottle.
Storage 4 - bromo - 3,5 - difluorobenzenesulfonyl chloride should be stored in a cool, dry, and well - ventilated area, away from heat sources and direct sunlight. Keep it in a tightly closed container, preferably made of corrosion - resistant materials due to its reactive nature. Store it separately from incompatible substances like oxidizing agents, bases, and moisture - containing materials to prevent unwanted reactions.
Shipping 4 - bromo - 3,5 - difluorobenzenesulfonyl chloride is a chemical. It should be shipped in well - sealed, corrosion - resistant containers, following strict hazardous chemical shipping regulations to ensure safety during transit.
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4-Bromo-3,5-Difluorobenzenesulfonylchloride 4-Bromo-3,5-Difluorobenzenesulfonylchloride
General Information
Historical Development
4-Bromo-3,5-difluorobenzenesulfonyl chloride is also a chemical product. At the beginning, many scholars studied the technology of chemical industry, hoping to create special substances. In the past, scholars exhausted the laboratory and tried various things to adjust the conditions of various reactions, such as temperature and the ratio of reagents, in order to prepare this compound.
At the beginning, the progress was slow, and every attempt encountered obstacles, the product was impure, or the yield was meager. However, many people made unremitting efforts to study the reaction mechanism carefully, taking into account the gains and losses in the past, and changed the experimental method. After years of research, the best method was gradually obtained, so that the preparation of this product became perfect.
As a result, the yield and purity of 4-bromo-3,5-difluorobenzenesulfonyl chloride are gradually increasing. Its application in chemical, pharmaceutical and other fields has gradually expanded with the advancement of technology, making it an important product in academia and industry.
Product Overview
4 - Bromo - 3,5 - Difluorobenzenesulfonylchloride is an important chemical substance. Its appearance is usually [specific appearance description], with specific physical properties, and melting boiling point [description of melting boiling point]. This substance has a wide range of uses in the field of organic synthesis and can participate in many reactions as a key intermediate.
Its preparation process requires rigorous operation, usually through [brief description of preparation method]. During the reaction, the reaction conditions such as temperature, pressure and proportion of reactants are strict, and slight deviations may affect the purity and yield of the product.
Because of its special functional groups such as bromine, fluorine and sulfonyl chloride, it is endowed with unique chemical activity. It can react with a variety of nucleophiles to construct novel organic compound structures, providing strong support for the development of medicinal chemistry, materials science and other fields, with considerable prospects.
Physical & Chemical Properties
4 - Bromo - 3,5 - Difluorobenzenesulfonyl chloride is a unique chemical substance. Its physical properties, the color is pure white, the shape is fine powder, and it exists stably at room temperature and pressure. Looking at its melting point, it is about a specific value range, and this characteristic makes it begin to change in a specific temperature environment. When it comes to solubility, it is soluble in some organic solvents, but insoluble in water, which is determined by its molecular structure and polarity.
Its chemical properties are also characteristic. The sulfonyl chloride group is quite active, easy to react with many nucleophiles, and can derive a variety of compounds. The presence of bromine and fluorine atoms also significantly affects its chemical activity and reaction path. Fluorine atoms have high electronegativity, which changes the distribution of molecular electron clouds, making the reaction more selective. Bromine atoms can participate in halogenation reactions, etc., providing various possibilities for chemical synthesis and being of great value in the field of organic synthesis.
Technical Specifications & Labeling
Today there is a thing called 4 - Bromo - 3,5 - Difluorobenzenesulfonylchloride. In terms of process specifications and identification (product parameters), it should be studied in detail. Its process specifications are related to the production method, and must be based on the precise method. The matching of materials, the time of heat, and the order of operation are all fixed, and there must be no mistakes.
As for the identification (product parameters), it is necessary to clarify its characteristics, such as color, taste, and state; know its purity geometry, and the impurities are few and thin; know its physical and chemical properties, the point of melting and boiling, and the ability to dissolve. In this way, it is an excellent product. To make this thing, the craftsman should strictly abide by the rules of the process and mark it accurately, so as to make a good product and supply it where needed.
Preparation Method
There is now a method for making 4 - Bromo - 3,5 - Difluorobenzenesulfonylchloride. First take the raw materials, bromine, difluorobenzenesulfonic acid, etc. The first step in the preparation process is to make the difluorobenzenesulfonic acid react with bromine under specific conditions. This reaction step must be moderately controlled to ensure a smooth reaction. After the reaction is completed, impurities are removed by purification.
Then, the resulting product is reacted with a chlorination reagent. The chlorination mechanism requires the help of a catalyst to accelerate the reaction process. During operation, pay attention to the cleanliness of the reaction environment to prevent impurities from mixing. After this series of steps, 4 - Bromo - 3,5 - Difluorobenzenesulfonylchloride can be obtained. Each step needs to be handled carefully and in accordance with the specifications to ensure the quality of the product.
Chemical Reactions & Modifications
Taste the technology of chemical industry, subtle and mysterious, in the research of compounds, every new environment. In today's words 4 - Bromo - 3,5 - Difluorobenzenesulfonylchloride this substance, its chemical reaction and modification, there is much to be investigated.
The reaction also requires careful adjustment of various conditions, such as temperature and solvent genus. High temperature is the reaction speed, and there may be a danger of side effects; low temperature is the reaction slow, and it may take too much time. The nature of the solvent is also related to the reaction direction. Polar solvents may promote their ionization, non-polar or nucleophilic substitution.
As for modification, various groups can be introduced to change their properties. Increasing its hydrophilicity may be beneficial for medical delivery; adding its conjugate structure may change its photoelectric properties. This is all due to our careful study, insight into its principles, and the improvement of the environment, so that this compound can be used to its fullest extent, contributing to the chemical industry and benefiting the world.
Synonyms & Product Names
4 - Bromo - 3,5 - Difluorobenzenesulfonylchloride is a chemical substance that I have been focusing on recently. This substance is also synonymous with many names and commodity names in the industry.
Its synonymous names may vary due to research perspectives and regional differences. Those with other names based on the characteristics of its chemical structure are designed to highlight the key role of a specific atom or group, so that researchers can more accurately grasp its essence.
As for the name of the product, merchants often give it a unique title in order to make it more recognizable and attractive in the market. Either it means excellent performance, or it is closely related to the application field, so that customers can quickly recognize its value and use.
For our chemical researchers, clarifying the synonyms and trade names of this substance will help to fully understand its status in the academic and commercial fields, and will also provide broader ideas for further research and application development, helping to promote the development and innovation of this chemical substance in related fields.
Safety & Operational Standards
4 - Bromo - 3,5 - Code of Safety and Operation of the Difluorobenzenesulfonylchloride
Fu 4 - Bromo - 3,5 - Difluorobenzenesulfonylchloride, is a chemical substance that is quite used in experiments and production. However, its properties are dangerous, so safety and operation standards are of paramount importance.
In terms of safety, this substance is corrosive and can cause burns when it touches the skin. If it is not carefully entered into the eyes, it will be especially harmful. Therefore, when touching, protective equipment such as gloves, goggles, etc. must be worn. And the volatile gas of this substance may be harmful to breathing. When operating in a well-ventilated place, it is more appropriate to have respiratory protective devices if necessary.
As for the operating specifications, when taking it, the method must be precise and avoid spilling. The utensils used should be clean and dry to prevent impurities from affecting their quality. When weighing, it is appropriate to use a precise weighing instrument. During the reaction process, temperature, time and other conditions should be strictly controlled and followed according to the established process. After the reaction, the remaining materials should not be discarded at will. When handled according to the prescribed method, to prevent pollution of the environment.
Furthermore, when storing, it should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Labels are clear, indicating its name, nature and hazards. In this way, it can be used to avoid its risks and ensure the safety and order of experiments and production.
Application Area
In today's world, there are names 4 - Bromo - 3, 5 - Difluorobenzenesulfonylchloride. This substance is used in many fields.
In the field of medicine, it can be used as a key intermediate to help physicians make special drugs to treat various diseases. Such as the development of antibacterial agents, with its unique structure, it can break the prevention of bacteria and cure diseases for all living beings.
In the world of materials, it can change the properties of materials. Adding to polymers can increase its corrosion resistance and heat resistance, making the material stable in harsh environments.
In the electronics industry, it may help to develop new electronic materials, optimize the performance of electronic components, and make electronic devices operate more stably and efficiently. From this point of view, this material has extraordinary value in many application fields and can contribute to the development of the world.
Research & Development
Today there is a product, named 4 - Bromo - 3,5 - Difluorobenzenesulfonylchloride. I am a chemical researcher, dedicated to the research and development of this substance.
This substance has unique chemical properties and has extraordinary potential in the field of organic synthesis. The combination of bromine, fluorine atom and sulfonyl chloride group gives special reactivity.
Through various experiments, I explore its reaction path and conditions. After repeated attempts, the synthesis method can be optimized to improve its yield and purity.
At the application level, this substance can be used as a key intermediate for the creation of new drugs and functional materials. I also look forward to its expansion in more fields, hoping to promote the progress of chemical-related industries and contribute to scientific development.
Toxicity Research
4-Bromo-3,5-difluorobenzenesulfonyl chloride is also a chemical substance. I am a chemical researcher, and I have studied the toxicity of this substance for a long time.
Looking at its structure, halogen elements coexist with sulfonyl chloride groups, or have strong chemical activity. According to common sense, sulfonyl chloride groups are easily hydrolyzed in contact with water, generating acidic substances, or have the ability to stimulate corrosion, which can hurt the skin and mucous membranes. And halogen elements also increase their chemical activity, or disturb biochemical reactions after entering the body, causing damage to organs and cells.
Although there is no detailed ancient book on its toxicity, it is deduced from chemical reasons. When handling this substance, one must be cautious and use protective equipment in a well-ventilated place to prevent its toxicity from reaching the body. In the future, the follow-up research will clarify its toxicity mechanism and serve as a safety measure.
Future Prospects
I have tried to research chemical products, and today I am talking about 4 - Bromo - 3,5 - Difluorobenzenesulfonylchloride this product. This product has unique chemical characteristics and has great potential in the field of synthesis. In the future, it may be used to create new medical drugs to treat various diseases and solve the suffering of the world. Or it may make achievements in material science and develop new materials with excellent performance to meet the needs of industry and people's livelihood. And it is expected to optimize the synthesis path, reduce costs and increase productivity, making production more efficient. I hope that with the power of our generation's scientific research, this product will shine in the future and benefit the world.
Where to Buy 4-Bromo-3,5-Difluorobenzenesulfonylchloride in China?
As a trusted 4-Bromo-3,5-Difluorobenzenesulfonylchloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Bromo-3,5-Difluorobenzenesulfonylchloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-bromo-3,5-difluorobenzenesulfonyl chloride?
4-Dimethylbenzaldehyde, which is an important chemical compound, has its main use.
First, it can be used in the synthesis field. It can be used as a medium and can be used in many compounds with special effects. For example, in the synthesis of some pain and anti-inflammatory compounds, 4-Dimethylbenzaldehyde can be used as a series of inverse compounds, and other compounds can be cleverly combined to gradually produce specific molecules of the product, so as to give the biological activity and processing function required by the product.
Second, it is also indispensable in the fragrance industry. Because of its own unique flavor, it can be used as a spice addition, adding a special fragrance to various flavors and fragrances. It is a daily flavor, used in perfumes, toiletries, etc., to make the product emit a charming fragrance; it is a edible flavor, added to candies, ingredients and other foods, with its unique flavor, 4-3, 5-dimethylbenzaldehyde can enhance its unique fragrance.
In addition, it is also effective in the synthesis. It can synthesize some high-efficiency and low-toxicity high-quality products. Through the reaction of other chemical raw materials, the obtained product can effectively prevent and control crop diseases and pests, and the impact of the environment is small, which meets the needs of today's development and helps to ensure the high efficiency of production.
Therefore, 4-3, 5-dimethylbenzaldehyde, with its special chemical properties, plays an important role in the development of various industries such as cooking, flavors, cooking, etc., and promotes the development of related technologies.
What are the synthesis methods of 4-bromo-3,5-difluorobenzenesulfonyl chloride?
To prepare 4-bromo-3,5-dimethylbenzenesulfonate barium, the method is as follows:
First take an appropriate amount of 3,5-dimethylbenzene and place it in a reactor. Slowly add bromine dropwise to it, supplemented by light or adding an appropriate catalyst, such as iron powder. This reaction aims to replace hydrogen atoms at specific positions on the benzene ring with bromine atoms to generate 4-bromo-3,5-dimethylbenzene. When reacting, pay close attention to the reaction temperature and dropwise speed to prevent side reactions from occurring.
After 4-bromo-3,5-dimethylbenzene is obtained, move it into another reaction vessel and add concentrated sulfuric acid. The purpose of this reaction is to introduce the sulfonic acid group into the benzene ring to form 4-bromo-3,5-dimethylbenzenesulfonic acid. During the reaction, temperature control is crucial, and it is generally necessary to carry out within a specific temperature range to ensure that the sulfonic acid group accurately replaces the hydrogen atom at the target position and reduces unnecessary side reactions.
When 4-bromo-3,5-dimethylbenzenesulfonic acid is prepared, it is mixed with barium hydroxide solution. The two react, and the sulfonic acid group is combined with barium ions to obtain 4-bromo-3,5-dimethylbenzenesulfonic acid barium. After the reaction is completed, the pure 4-bromo-3,5-dimethylbenzenesulfonate product can be obtained through filtration, washing, drying and other steps.
Each step of the reaction requires fine operation, and the reaction conditions are strictly controlled, such as temperature, reactant ratio, reaction time and other factors. A slight difference may affect the purity and yield of the product. In this way, the ideal 4-bromo-3,5-dimethylbenzenesulfonate barium can be obtained.
What are the physical properties of 4-bromo-3,5-difluorobenzenesulfonyl chloride?
4-Bromo-3,5-difluorobenzaldehyde is an organic compound with unique physical properties and is widely used in chemical, pharmaceutical and other fields. The following are brief descriptions of its physical properties:
- ** Appearance and Properties **: At room temperature, 4-bromo-3,5-difluorobenzaldehyde is mostly colorless to light yellow liquid, with a clear appearance and high visual recognition. This appearance feature is closely related to its molecular structure. The benzene ring, bromine atoms and fluorine atoms work together to give it a specific physical form.
- ** Melting Point and Boiling Point **: The melting point is about -20 ° C, and the boiling point is between 200-205 ° C. The lower melting point causes it to be liquid at room temperature, and the specific boiling point allows it to realize gas-liquid transformation at the corresponding temperature. This is of great significance for the separation, purification and control of reaction conditions of compounds. If the appropriate temperature is set according to the boiling point during distillation and purification, the substance can be effectively separated.
- ** Density and solubility **: The density is about 1.7 g/cm ³, which is more dense than water. If mixed with water, it will sink to the bottom. Slightly soluble in water, but easily soluble in most organic solvents, such as ethanol, ether, dichloromethane, etc. This is because the compound is an organic molecule with certain hydrophobicity, and there is a similar miscibility with organic solvents. This solubility is conducive to the selection of suitable solvents in organic synthesis and promotes the reaction.
- ** Odor **: 4-Bromo-3,5-difluorobenzaldehyde has a special pungent odor. Although it is difficult to describe accurately, its odor is unique and easy to distinguish. Note when using, because its pungent odor may irritate the respiratory tract and skin, the operation should be carried out in a well-ventilated environment.
What are the precautions for 4-bromo-3,5-difluorobenzenesulfonyl chloride in storage and transportation?
4-% hydrazine-3,5-difluorobenzaldehyde oxime is a highly toxic substance. When storing and transporting, the following things must be paid attention to:
First, the storage device must be made of corrosion-resistant materials. Because of its strong corrosive nature, if the container is not corrosion-resistant, it is easy to be eroded and cause leakage, which can cause disaster. Therefore, containers made of glass, polytetrafluoroethylene, etc. should be selected to ensure their chemical stability and do not react with the stored materials.
Second, the storage place must be cool and dry, away from fire and heat sources. This substance can easily cause combustion or even explosion when heated or exposed to open flames. And humid environments can easily cause it to deteriorate, affecting quality and safety.
Third, when transporting, the packaging must be firm. Professional packaging materials are required, with multiple layers of protection, anti-collision and anti-vibration, to avoid damage to the packaging due to bumps.
Fourth, obvious warning signs should be set up in storage and transportation places. Explicit its toxicity and danger, so that everyone can be alert and not easily approached to prevent accidental contact.
Fifth, the operator must undergo professional training. Familiar with the characteristics of this substance, its dangers and emergency treatment methods. During storage and transportation, strictly follow the operating procedures to prevent illegal operations.
Sixth, prepare perfect emergency rescue facilities and plans. In the event of an accident such as a leak, it can respond quickly and deal with it effectively to minimize the harm. Such as equipping suitable adsorbents to deal with leaks and preparing corresponding antidotes and other emergency medicines.
What is the market price range for 4-bromo-3,5-difluorobenzenesulfonyl chloride?
4-Bromo-3,5-dimethylbenzaldehyde is an important intermediate in organic synthesis, which is used in many fields such as medicine, pesticides and materials. Its market price range will be affected by many factors, such as production process, purity requirements, market supply and demand situation, etc.
Generally speaking, the purity of this chemical has a significant impact on the price. If the purity is above 98%, the price per gram may be in the range of 30 to 80 yuan in small-scale purchasing scenarios. For higher purity such as 99% and above, the price may climb to 80 to 150 yuan per gram.
The production process also affects the price. If an efficient, environmentally friendly and cost-controllable process is used, the price may be relatively stable. On the contrary, if the process is complicated and the cost is high, the price will increase automatically.
In terms of market supply and demand, prices may rise during peak demand seasons or supply shortages; when supply exceeds demand, prices may have a downward trend.
Purchasing volume also affects the price. When purchasing on a large scale, due to the scale effect, suppliers may give price concessions, and the price per gram may drop to about 20 yuan, or even lower.
It should be noted that the market price is in dynamic changes. The specific price should be consulted with relevant chemical product suppliers and distributors, or with reference to real-time quotations on chemical product trading platforms to obtain accurate price information.