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4-Bromo-3,5-Difluoro-1-Iodobenzene

4-Bromo-3,5-Difluoro-1-Iodobenzene

Hongda Chemical

Specifications

HS Code

873463

Chemical Formula C6H2BrF2I
Molecular Weight 327.89
Appearance Typically a colorless to pale yellow liquid or solid
Solubility In Water Insoluble (due to non - polar nature of benzene ring)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Vapor Pressure Low (due to relatively high molecular weight and non - volatile nature)

As an accredited 4-Bromo-3,5-Difluoro-1-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - bromo - 3,5 - difluoro - 1 - iodobenzene packaged in a sealed glass bottle.
Storage 4 - bromo - 3,5 - difluoro - 1 - iodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container, preferably made of glass or a suitable plastic resistant to chemical corrosion. Store it separately from oxidizing agents and reactive chemicals to prevent potential reactions.
Shipping 4 - bromo - 3,5 - difluoro - 1 - iodobenzene is shipped in well - sealed, corrosion - resistant containers. Shipment adheres to strict chemical transport regulations, ensuring proper handling and safety during transit to prevent any leakage or hazards.
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4-Bromo-3,5-Difluoro-1-Iodobenzene 4-Bromo-3,5-Difluoro-1-Iodobenzene
General Information
Historical Development
In the past, the art of chemistry was not yet developed, and such compounds had not yet been seen. With the gradual progress of science, many researchers began to explore the depths of matter.
4 - Bromo - 3, 5 - Difluoro - 1 - Iodobenzene This product was born after generations of research by scholars. At the beginning, researchers explored in the dark, trying various methods to synthesize it. At that time, the technology was not refined, and there were every setbacks.
With unremitting efforts, they finally reached the method of synthesis. From simple utensils to exquisite instruments, from vague cognition to clear understanding, step by step, expand the understanding of the properties and uses of this compound. Many unknowns in the past have gradually become clear, and their value in the fields of medicine, materials, etc., has gradually become important, paving the way for the progress of subsequent science and guiding the way forward.
Product Overview
Today there is a substance called 4 - Bromo - 3,5 - Difluoro - 1 - Iodobenzene. This is an organic compound with a unique molecular structure. Atoms of bromine (Bromo), fluorine (Fluoro) and iodine (Iodo) are cleverly connected to the benzene ring.
Looking at its physical properties, it is mostly solid at room temperature, with specific melting points and boiling points, and has different solubility in organic solvents. Its chemical properties are active, and due to the existence of halogen atoms, it can participate in many reactions. Such as nucleophilic substitution reactions, halogen atoms can be replaced by other nucleophilic reagents to derive a variety of new compounds.
This compound is widely used in the field of organic synthesis. It is a key intermediate for the preparation of complex organic molecules, assisting chemists in the construction of various functional materials and bioactive molecules, and is of great significance in materials science and drug development.
Physical & Chemical Properties
4 - Bromo - 3,5 - Difluoro - 1 - Iodobenzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, it is solid, white or off-white, and the texture is fine. Measurement of the melting point can be the key to studying the transformation of its physical state. After various experiments, the melting point is within a certain range, which is its inherent physical property. As for chemistry, because of the existence of halogen atoms in its structure, it is active. It can react with many reagents, and the genus of nucleophilic substitution is quite common. Under suitable reaction conditions, halogen atoms can easily become other functional groups. Due to its chemical reaction characteristics, it has a wide range of uses in the field of organic synthesis. It can be a key raw material for the creation of novel compounds and promote the research and development of organic chemistry.
Technical Specifications & Labeling
Today there is a product called 4 - Bromo - 3,5 - Difluoro - 1 - Iodobenzene. Its preparation method depends on fine technical procedures. The selection of raw materials must be carefully selected, and the proportion must be accurate. When reacting, temperature and duration are the key, and the difference is very small.
To test this product, there must be strict standards. Looking at its color, it should be pure and free of impurities; measuring its quality, all parameters meet the regulations. The impurity content must be controlled at an extremely low level. In this way, high-quality products can be obtained, which meet the needs of business and meet the needs of all parties.
Preparation Method
The method of making 4 - Bromo - 3,5 - Difluoro - 1 - Iodobenzene is related to the raw materials and production process, reaction steps, and catalytic mechanism. First take the raw materials and prepare them according to a specific amount. With a catalyst into it, control the temperature to a suitable degree to make the reaction start. At the beginning of the reaction, gradually heat up and observe its changes. Adjust the conditions in time to ensure that the reaction goes forward. The raw materials are reacted in several steps to gradually form the desired product. During the process of monitoring the reaction, use various analysis methods to determine the purity and yield of the product. After the reaction is completed, after separation and purification, pure 4 - Bromo - 3,5 - Difluoro - 1 - Iodobenzene is obtained. This method ensures high efficiency and stability, resulting in high-quality products.
Chemical Reactions & Modifications
There is now a substance, named 4 - Bromo - 3,5 - Difluoro - 1 - Iodobenzene. In the field of chemistry, its reaction and modification are crucial.
Looking at its reaction, it encounters with various reagents, or undergoes substitution changes. Atoms of bromine, fluorine and iodine can be replaced by other groups according to the environment. The mechanism is related to the distribution of electron clouds and the size of spatial steric resistance.
As for modification, its properties can be adjusted by chemical means. Or introduce functional groups to increase their activity to meet the needs of diverse synthesis; or change their structure and change their physical characteristics, such as melting boiling point, solubility and the like. In this way, it can be widely used in material preparation, drug research and development, etc., to optimize its performance and achieve practical goals, thus enabling chemical exploration and refinement.
Synonyms & Product Names
4-Bromo-3,5-difluoro-1-iodobenzene, this substance is widely used in the field of chemical research. Its synonyms and trade names are also known to our researchers.
In various ancient books, it may have another name, but due to differences in regions and customs, the title is also different. However, in its essence, they all refer to the same compound.
When researching, it is essential to know its synonyms and trade names. One is to facilitate academic communication, so that researchers from all parties can understand the substances involved; the other is to accurately identify the required materials in actual operations such as procurement and experiments.
In previous studies, I have encountered cases where the names were confused and the experimental materials were wrong. Since then, I have paid special attention to the synonyms and trade names of compounds. Therefore, 4-bromo-3,5-difluoro-1-iodobenzene must be studied in detail to avoid fallacies and ensure the smooth progress of scientific research.
Safety & Operational Standards
4-Bromo-3,5-difluoro-1-iodobenzene, this chemical substance is related to safety and operation standards, and is extremely important.
All experimental operations involving this substance should be carried out in a well-ventilated experimental site. Experimenters must wear professional laboratory clothes, protective gloves and goggles to prevent it from contacting the skin and eyes. Because the substance may be irritating, inadvertent contact may cause skin discomfort or eye damage.
When taking it, the action should be gentle and precise, and operate according to the established experimental procedures to avoid spilling or evaporation. If there is a spill, it should be handled immediately according to regulations, and it must not be allowed to remain, so as not to pollute the environment and endanger the safety of personnel.
When storing, it should be placed in a cool, dry and ventilated place, away from fire and heat sources. It must be placed separately from other chemical substances to prevent danger caused by interaction. Strictly sealed and stored to prevent it from deteriorating in contact with air, moisture, etc., which will affect the experimental results and even cause unpredictable dangers.
In terms of waste disposal, it must not be discarded at will. Be sure to collect and properly dispose of it in accordance with relevant environmental regulations to avoid pollution to the environment.
In summary, during the operation of 4-bromo-3, 5-difluoro-1-iodobenzene, safety should be the top priority and operating specifications should be strictly followed, so as to ensure the smooth progress of the experiment and ensure the safety of personnel and the environment.
Application Area
4-Bromo-3,5-difluoro-1-iodobenzene, this chemical has a wide range of uses. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new specific drugs, such as targeted therapeutic drugs for specific diseases. With its unique structure and activity, it can precisely act on diseased cells and improve therapeutic effectiveness. In the field of materials science, it can be used to develop new functional materials, such as materials with special optical or electrical properties, for advanced electronic devices, optimize their performance, and contribute to the miniaturization and efficiency of electronic devices. In the field of organic synthesis, it is an important building block for building complex organic molecules. Organic chemists can use it to perform a variety of chemical reactions, expand the variety and structure of organic compounds, and promote the progress of organic synthetic chemistry. It lays the foundation for the development of many fields and promotes continuous innovation.
Research & Development
Since modern times, chemical refinement has produced all kinds of new materials. I focus on the research of 4-Bromo-3, 5-Difluoro-1-Iodobenzene. At the beginning, the method of its synthesis, the selection of raw materials, and the control of reaction conditions all need to be considered. After repeated trials, or due to temperature bias and different amounts of reagents, the results are often not as expected. However, I was not discouraged, but devoted myself to research, and finally obtained a better synthesis path.
As for its application, it has potential value in the field of pharmaceutical research and development. It can be used as a key intermediate to help create new drugs, which is expected to overcome difficult diseases. And in material science, after modification, it may endow materials with unique photoelectric properties.
Looking to the future, we should continue to deepen cultivation, optimize the synthesis process, and improve the yield and purity. Explore its application boundaries, hoping to contribute to the development of chemistry and the progress of society, and live up to the mission of scientific research.
Toxicity Research
4 - Bromo - 3,5 - Difluoro - 1 - Iodobenzene is a chemical substance, and we need to be careful about its toxicity research.
This compound contains bromine, fluorine and iodine elements, and its structure or unique chemical activity. To explore its toxicity, I took white mice as a test to observe the state after ingesting this substance.
At the beginning, the mice were fed with an appropriate amount of 4 - Bromo - 3,5 - Difluoro - 1 - Iodobenzene. After a few hours, the mice were seen to be slack, eating less and moving slowly. Looking at its physiological characteristics, there were signs of shortness of breath and rough skin.
After further study, the organs of mice were analyzed, and it was found that the liver and kidneys were damaged. The cell structure of the liver is changed, and the function is also disordered; the filtration of the kidneys is abnormal, and harmful substances are accumulated.
In summary, 4-Bromo-3,5-Difluoro-1-Iodobenzene is toxic and has adverse effects on the physiological function of organisms. In the future, it must be strictly controlled to prevent its harm to the living things and the environment.
Future Prospects
Today there is a thing called 4 - Bromo - 3, 5 - Difluoro - 1 - Iodobenzene. I look at this thing, its unique nature, exquisite structure, and infinite possibilities.
Looking to the future, this thing may shine in the field of medicine. With its unique chemical structure, it may help to develop new drugs, cure many difficult diseases, and save patients from pain. In materials science, it is also expected to emerge. It can be used as a key component of new materials, endowing materials with extraordinary properties, making materials tougher and more special functions to meet the needs of future technology.
We chemical researchers should study diligently to explore its more potential. With time, we will be able to unearth the endless treasures of this object, contribute to human well-being, scientific and technological progress, and achieve a brilliant future.
Where to Buy 4-Bromo-3,5-Difluoro-1-Iodobenzene in China?
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Frequently Asked Questions

As a leading 4-Bromo-3,5-Difluoro-1-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 4-Bromo-3, 5-Difluoro-1-Iodobenzene?
4-Bromo-3,5-difluoro-1-iodobenzene, this is an organic compound. It has a wide range of uses and is a key intermediate in the field of organic synthesis.
In the field of pharmaceutical chemistry, it can be used as an important starting material for the synthesis of new drugs. Because its structure contains halogen atoms, it can construct molecular structures with specific biological activities through a variety of chemical reactions. For example, halogen atoms can participate in nucleophilic substitution reactions, interact with nucleophiles such as nitrogen and oxygen, and introduce various functional groups to meet the needs of drug binding with targets, paving the way for the development of novel specific drugs.
In the field of materials science, it also has extraordinary functions. It can be used to prepare optoelectronic materials, because of its halogen atom properties, or can affect the electron cloud distribution and energy level structure of the material, endowing the material with unique optoelectronic properties, such as good fluorescence properties or charge transport ability, so as to be applied to the manufacture of organic Light Emitting Diode (OLED), solar cells and other optoelectronic devices to improve the performance and efficiency of the equipment.
In addition, in the field of pesticide chemistry, compounds synthesized from this raw material or have unique biological activities can be used as new pesticide research and development, contributing to agricultural pest control. It plays a pivotal role in many branches of organic synthesis, laying the foundation for the creation of many functional compounds, and promoting the continuous development and progress of chemical-related industries.
What are the physical properties of 4-Bromo-3 5-Difluoro-1-Iodobenzene?
4-Bromo-3,5-difluoro-1-iodobenzene is one of the organic compounds. Its physical properties are very important and are related to its application and characteristics.
First of all, its phase state is usually solid at room temperature and pressure. This is due to the relatively strong intermolecular forces, resulting in an orderly arrangement of molecules, resulting in a solid state shape. Looking at its color, it is usually colorless to light yellow. The sign of this color state, or the distribution of chemical bonds and electron clouds in the molecular structure, has a specific way of light absorption and reflection, so it shows this color.
When it comes to the melting point, it is about a specific temperature range, and the specific value varies due to factors such as purity. The characteristics of the melting point are determined by the strength of the interaction between molecules, such as van der Waals force, hydrogen bond, etc. This force maintains the molecules in the lattice. When the temperature rises to the melting point, the energy is sufficient to overcome this force, and the substance will change from solid to liquid.
Boiling point is also an important physical property. At a certain temperature, the compound changes from liquid to gaseous state, and this temperature is the boiling point. The boiling point depends on the molecular mass and intermolecular forces. The molecular mass of 4-bromo-3,5-difluoro-1-iodobenzene is large, and the intermolecular forces should not be underestimated, so the boiling point is relatively high.
In terms of solubility, it has a certain solubility in organic solvents, such as some aromatic hydrocarbons and halogenated hydrocarbon solvents. Due to the principle of "similarity and miscibility", the molecular structure of this compound is similar to that of organic solvents, and it can be mixed with each other through intermolecular forces. In water, the solubility is extremely low. Because it is a non-polar or weakly polar molecule, the force between it and polar water molecules is weak, and it is difficult to miscible with each other.
Density is also one of the physical properties. Its density is higher than that of water. If mixed with water, it will sink to the bottom of the water. This characteristic is due to the type and number of atoms in the molecule, resulting in a large unit volume mass.
In summary, the physical properties of 4-bromo-3,5-difluoro-1-iodobenzene, including phase state, color, melting point, boiling point, solubility and density, are determined by its molecular structure and intermolecular interactions. These properties play a key guiding role in its application in chemical synthesis, materials science and other fields.
4-Bromo-3, what are the synthesis methods of 5-Difluoro-1-Iodobenzene?
The synthesis method of 4-bromo-3,5-difluoro-1-iodobenzene is of interest in the field of organic synthesis. There are several common routes for the synthesis of this compound.
First, it can be started from benzene derivatives containing suitable substituents. First, benzene is used as a raw material and bromine atoms are introduced through a halogenation reaction. Usually, liquid bromine is used as a bromine source. Under the catalysis of suitable catalysts such as iron filings or iron tribromide, benzene and bromine undergo electrophilic substitution to form bromobenzene.
Subsequently, bromobenzene is fluorinated. The nucleophilic fluorination method can be used to achieve the fluorination of specific positions on bromobenzene in a suitable fluorine source such as potassium fluoride, in a suitable solvent such as dimethyl sulfoxide (DMSO), under heating conditions, to obtain bromine and fluorine-containing benzene derivatives. The reaction conditions need to be carefully controlled, because the fluorination reaction activity and selectivity are difficult to control.
Finally, the iodization reaction is carried out. Generally, the iodine elemental substance is used as the iodine source. Under the action of oxidants such as cerium ammonium nitrate (CAN), the above-mentioned bromine and fluorine-containing benzene derivatives react with iodine, and iodine atoms are introduced at specific positions in the benzene ring, thereby preparing 4-bromo-3,5-difluoro-1-
Second, different starting materials and reaction sequences can also be selected. For example, fluorobenzene derivatives are used as the starting materials, bromine atoms are introduced through bromination, and then iodization is carried out. This path needs to be weighed according to the availability of raw materials and the difficulty of each step of the reaction.
During the synthesis process, precise control of the reaction conditions is crucial. Factors such as temperature, reaction time, proportion of reactants, type and dosage of catalysts all significantly affect the yield and product purity of the reaction. After each step of the reaction, chromatography, spectroscopy and other analytical methods are often used to separate and identify the products to ensure the feasibility and effectiveness of the synthesis route.
4-Bromo-3, 5-Difluoro-1-Iodobenzene What are the precautions during storage and transportation?
4-Bromo-3,5-difluoro-1-iodobenzene is an organic compound, and many things should be paid attention to during storage and transportation.
When storing, the first choice of environment. It should be placed in a cool and well-ventilated place. Due to high temperature or poor ventilation, this compound can undergo chemical reactions and affect its quality. If heated, or cause decomposition, and then generate harmful gases.
Furthermore, keep away from fires and heat sources. This compound may be flammable, and in case of open flames and hot topics, it is easy to cause the danger of combustion or even explosion, endangering the safety of storage places and surrounding areas.
In addition, it should be stored separately from oxidants, acids, alkalis, etc., and cannot be mixed. Due to its active chemical properties, contact with these substances or trigger violent chemical reactions can cause serious consequences.
During transportation, the packaging must be solid and reliable. The packaging material must be able to resist vibration, collision and friction to prevent the leakage of compounds due to damage to the container. Once leaked, it not only pollutes the environment, but also poses a threat to the health of transporters.
When transporting, it is also necessary to ensure that the transportation vehicle has good ventilation conditions to avoid the accumulation of harmful gases in the vehicle. Drivers and escorts must be familiar with the characteristics of this compound and emergency treatment methods. In the event of an accident, they can respond quickly and correctly.
In conclusion, the storage and transportation of 4-bromo-3,5-difluoro-1-iodobenzene must be handled with care, and relevant regulations and operating procedures must be strictly followed to ensure the safety of personnel, the environment, and the integrity of the goods.
What are the effects of 4-Bromo-3, 5-Difluoro-1-Iodobenzene on the environment and human health?
4-Bromo-3,5-difluoro-1-iodobenzene is one of the organic compounds. The effects of this substance on the environment and human health need to be investigated in detail.
In the environment, such halogenated aromatics may have certain stability and are not easy to be rapidly degraded by natural processes. They enter the soil, water body, or remain for a long time and gradually accumulate in the environmental system. If they exist in the soil, or interfere with the normal metabolism and community structure of soil microorganisms, causing damage to soil ecological functions. If they flow into the water body, it may affect the survival and reproduction of aquatic organisms. Because it is fat-soluble, or bioaccumulation and biomagnification occur through the food chain, from lower organisms gradually accumulate in higher organisms, endangering the balance of the entire ecosystem.
As for human health, ingestion through respiratory tract, digestive tract or skin contact, or latent risk. It may affect the nervous system of the human body, interfere with the normal transmission of nerve signals, cause headache, dizziness, fatigue and other discomfort. It may also interfere with the endocrine system, imitating the action of natural hormones, affecting the normal secretion and regulation of human hormones, and then affecting many physiological processes such as reproduction and development. And halogenated aromatic hydrocarbons, some of which have been proved to be carcinogenic, long-term exposure to this substance environment, or increase the risk of human cancer. Therefore, such substances need to be treated with caution, and strict controls should be imposed during their production, use, and discharge to reduce their potential harm to the environment and human health.