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4-Bromo-2-(Trifluoromethoxy)Benzenethiol

4-Bromo-2-(Trifluoromethoxy)Benzenethiol

Hongda Chemical

    Specifications

    HS Code

    374900

    Chemical Formula C7H4BrF3OS
    Molecular Weight 273.07
    Appearance Solid (Typical)
    Solubility In Water Low solubility, as it is an organic compound with non - polar groups
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Pka Related to the thiol group, value would be characteristic of aromatic thiols
    Vapor Pressure Low vapor pressure at room temperature

    As an accredited 4-Bromo-2-(Trifluoromethoxy)Benzenethiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - bromo - 2 - (trifluoromethoxy)benzenethiol in sealed chemical - grade vial.
    Storage 4 - bromo - 2 - (trifluoromethoxy)benzenethiol should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant material due to its potentially reactive nature. Store it separately from oxidizing agents and incompatible substances to prevent chemical reactions.
    Shipping 4 - bromo - 2 - (trifluoromethoxy)benzenethiol is shipped in well - sealed, corrosion - resistant containers. It follows strict chemical shipping regulations, ensuring proper handling to prevent spills and exposure during transit.
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    4-Bromo-2-(Trifluoromethoxy)Benzenethiol 4-Bromo-2-(Trifluoromethoxy)Benzenethiol
    General Information
    Historical Development
    Wenfu 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol has its origin, and at the beginning, the researchers did not know its properties. The chemical sages of the past gradually touched the trace of this thing on the road of exploration.
    At that time, the chemical technology was not as exquisite as it is today, but the public studied it unremittingly. Those who first paid attention to the benzenethiol containing halides, after years of experiments and analysis, found that the characteristics of 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol are unique.
    In the early days, only part of its reaction was roughly known. Later, with the improvement of instruments and the completion of theory, the understanding of its structure and reaction mechanism became deeper. From the initial synthesis attempt to the method of gradually optimizing the preparation, every step is the hard work of all researchers. Its unique use in the field of organic synthesis gradually paves the way for more chemical creations in the future, and it has also become a shining link in the long river of chemical development.
    Product Overview
    4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol is a unique chemical substance. Its properties are unique and have specific physical and chemical properties. Among this compound, the bromine atom is cleverly connected to the trifluoromethoxy group and the phenylthiophenol group, and the structure is unique.
    From the perspective of physical properties, it may have a specific color, taste and morphology. The melting point also has its own characteristics, which lays the foundation for its existence under specific conditions. Chemically, due to the functional groups it contains, it may exhibit active reactivity.
    In the field of organic synthesis, 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol can be used as a key intermediate. With the reactivity of its functional groups, it can participate in many organic reactions, such as nucleophilic substitution, coupling reactions, etc., to assist in the synthesis of more complex and special functional organic compounds, which may have potential applications in pharmaceutical chemistry, materials science and other fields.
    Physical & Chemical Properties
    4-Bromo-2 - (trifluoromethoxy) thiophenol, this substance has unique physical and chemical properties. Its appearance may be colorless to light yellow liquid, with a special smell. Melting point, boiling point and other physical properties vary depending on the precise determination conditions. Chemically, thiophenol groups have certain reactivity and can participate in a variety of chemical reactions. Bromine atoms can undergo substitution reactions, and trifluoromethoxy groups endow them with unique electronic effects and stability. These physical and chemical properties make it widely used in the field of organic synthesis. It can be used as a key intermediate to participate in the construction of complex organic molecular structures, providing a foundation for innovative drug research and development, new material creation, etc. It is of great significance in modern chemical research and industrial production.
    Technical Specifications & Labeling
    4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol is a particularly important chemical substance. Its process specifications and identification (product parameters) are crucial in our field of chemical research.
    When it comes to process specifications, it is necessary to ensure that the preparation process is fine and correct. The selection of raw materials must be pure and well, and the reaction conditions must be precisely controlled. Parameters such as temperature, pressure, reaction time, etc. must be strictly implemented according to specific standards. In this way, the quality of the product can be guaranteed to be stable and meet the established specifications.
    In terms of product identification, clear and accurate labeling of various parameters, such as purity, composition, molecular weight, etc., is of paramount importance. This not only allows subsequent users to accurately understand the characteristics of the product, but also helps to properly dispose of it according to its characteristics during storage and transportation to avoid mistakes due to unclear identification. Only by strictly following the process specifications and accurate identification can we obtain high-quality 4-Bromo-2 - (Trifluoromethoxy) Benzenethiol products, which can play their due role in chemical research and related applications.
    Preparation Method
    The preparation method of 4-bromo-2 - (trifluoromethoxy) thiophenol is related to the raw material and production process, reaction steps and catalytic mechanism.
    First take an appropriate amount of halogenated aromatics, such as bromine-containing benzene compounds, and a specific trifluoromethoxy-containing reagent into the reactor in a certain molar ratio. A suitable organic solvent is pre-placed in the kettle to facilitate uniform mixing of the reactants. Then add an appropriate amount of catalyst, which must be able to effectively promote the substitution reaction of halogenated groups and trifluoromethoxy groups.
    Warm up to a specific temperature range, maintain this temperature, and make the two fully react. During this period, the reaction process needs to be closely monitored to determine the degree of reaction by means of chromatography and other analytical methods. When the reaction reaches the expected level, the temperature is lowered, the reaction liquid is poured into the separation funnel, and the impurities are removed through extraction, washing and other steps. Then, through distillation, recrystallization and other purification methods, the pure 4-bromo-2- (trifluoromethoxy) phenylthiophenol product is obtained. In this way, the preparation of this compound can be obtained.
    Chemical Reactions & Modifications
    Guanfu 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol, in the field of chemistry, the study of its reaction and modification is of great importance.
    In the past, in order to make this product, many traditional methods were relied on, but the drawbacks were also obvious. The reaction conditions are strict, non-high temperature or strong pressure, and the yield is not ideal, and there are many impurities.
    Today, Zhu Xian has worked tirelessly to study, and the improved method is gradually emerging. The new way is produced under mild conditions, with high efficiency, the yield can be improved, and the quality is also excellent. The reason is that the reaction mechanism is understood, and the precise regulation is made, so that the molecular rearrangement is orderly and the bonding is appropriate.
    The beauty of chemistry lies in the continuous innovation. The reaction and modification of this substance are just proof. With time, it will be able to emerge in more fields and be used by the world.
    Synonyms & Product Names
    Today there is a thing called 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol. This chemical thing, its synonymous name and commodity name, is also of concern to us.
    In the field of chemistry, there are many things, due to different purposes, uses and situations. 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol, or its structural sign, is named so. However, in various industries, or for the convenience of communication and identification, another name is given to the product.
    It is a synonymous name, so it helps everyone to understand the characteristics and categories of this thing. The name of the product is related to the promotion and identification of the market. Both have their own weight and complement each other. At the time of research, the name of the synonym can be passed on to various documents; at the time of trade, the name of the commodity can be known to trade freely. Therefore, it is indispensable in chemical research and application to explore the name of the synonym and the name of the commodity.
    Safety & Operational Standards
    4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol Safety and Operation Specifications
    F 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol is an important substance in chemical research. Safety regulations are essential in its experimental operation and storage.
    As far as storage is concerned, it must be placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent them from causing danger due to heat. And it must be stored separately from oxidizing agents, acids, etc., and must not be mixed with storage. The lid is chemically active, and it is easy to react chemically when mixed with various substances, which poses a safety risk.
    When operating, the experimenter should wear appropriate protective clothing, protective gloves and goggles. If this substance comes into contact with the skin and eyes, it will cause harm. The operating environment needs to be well ventilated to prevent its volatile gas from accumulating in the air and causing poisoning and other accidents. If you accidentally come into contact with this substance during operation, those who come into contact with the skin should immediately rinse with a large amount of flowing water and seek medical treatment; if it enters the eyes, lift the eyelids and rinse with flowing water or normal saline. You also need to seek medical attention immediately.
    Furthermore, the experimental operation process must be rigorous. When taking this substance, operate according to the exact amount required, and do not increase or decrease at will. After the operation is completed, properly dispose of the remaining substances and experimental waste, do not discard them at will, and centrally dispose of them in accordance with relevant regulations to protect the environment and the safety of others. In short, in the use of 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol, strictly observe safety and operating standards to ensure the smooth operation of the experiment and the safety of personnel and the environment.
    Application Area
    Today, there is a product called 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol, which is of great value in various application fields.
    In the field of medicine, this compound can be used as a key intermediate. Because of its unique structure, it can interact with specific targets in the body. Through delicate chemical reactions, it can be prepared to treat specific diseases, such as for certain inflammatory or nervous system diseases, or can play a miraculous role, providing new ways for doctors to treat diseases.
    In the material industry, it also has extraordinary performance. Using it as a raw material and treated by special processes, materials with special properties can be prepared. With good stability, or unique optical and electrical properties, it can be applied to high-end electronic equipment to make the equipment performance better and contribute to the development of materials science.
    In the field of chemical synthesis, it is like a magic key that opens the door to the synthesis of many complex compounds. With its special functional groups, it can guide the reaction to proceed accurately, synthesize novel structures and unique functions, and promote the chemical industry to a new height.
    Research & Development
    Today's research on 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol is crucial to our scientific research. Examining its properties in detail, its structure is unique, containing bromine, trifluoromethoxy and thiol groups, and this unique combination gives it unique characteristics.
    Study its synthesis method, and explore various paths after many attempts. Or start from the benzene ring and introduce the corresponding groups in a specific order; or choose another method to strive for efficient and pure synthesis. However, the synthesis process is full of difficulties, and the reaction conditions need to be precisely controlled. A slight difference in temperature and reagent ratio will affect the yield and purity.
    Looking forward to its development, it is expected to shine in the field of medicine. Due to its structural characteristics, it may act on specific targets and become a good medicine for treating diseases. Or there are new breakthroughs in the field of materials, contributing to the research and development of new functional materials. We should make unremitting efforts to explore its potential and contribute to scientific research progress and social development.
    Toxicity Research
    Toxicity Study of 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol
    There is a substance named 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol, which is common in our chemical studies. The study of the toxicity of this substance is quite important.
    After various experiments, 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol has various effects on living organisms. In small animals, it is seen that after ingesting this substance, their physiological functions are disordered. Breathing, heartbeat may be abnormal, and they are listless and slow to move.
    The effect of 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol on cells was also explored. In vitro cell experiments, it can damage cell structure and function. Or cause cell membrane rupture, damage to organelles, and affect cell metabolism and proliferation.
    In summary, 4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol is toxic. When used and produced, strict protective measures should be set up to avoid damage to organisms and the environment.
    Future Prospects
    4 - Bromo - 2 - (Trifluoromethoxy) Benzenethiol is a chemical substance I have studied. Looking to the future, its application prospects are quite broad. In the field of medicine, it is expected to become a key raw material for the development of new specific drugs after in-depth research, or to make breakthroughs in the treatment of specific diseases. In the field of materials science, its unique chemical properties may help to develop new functional materials, such as those with special optical and electrical properties, to meet the needs of high-end technology industries. Furthermore, in fine chemicals, it may become the core component of the synthesis of high-end fine chemicals, improving product quality and performance. With time and unremitting research, this substance will surely shine, contribute to the development of many fields, open up new prospects, and achieve unfulfilled expectations.
    Where to Buy 4-Bromo-2-(Trifluoromethoxy)Benzenethiol in China?
    As a trusted 4-Bromo-2-(Trifluoromethoxy)Benzenethiol manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-2-(Trifluoromethoxy)Benzenethiol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 4-Bromo-2- (Trifluoromethoxy) Benzenethiol?
    4-Bromo-2 - (trifluoromethoxy) thiophenol, an important compound in the field of organic chemistry. It has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to assist in the synthesis of drug molecules with specific biological activities. The genthiophenol group and fluorine-containing structure endow the molecule with unique physicochemical and biological properties, which can enhance the affinity of drugs and targets and improve pharmacokinetic properties.
    In the field of materials science, it also has outstanding performance. It can participate in the preparation of functional materials, such as fluorothiophenol-modified polymers or organic semiconductor materials. The fluorine-containing structure can improve the stability, corrosion resistance and hydrophobicity of the material, while the thiophenol group can build a cross-linked structure or achieve surface modification through chemical reaction, endowing the material with novel electrical, optical or mechanical properties.
    In organic synthetic chemistry, 4-bromo-2 - (trifluoromethoxy) phenylthiophenol is used as a multifunctional reagent to participate in many organic reactions. For example, through the selective reaction of bromine atoms and thiophenol groups, complex organic molecular structures can be constructed, providing a rich strategy for organic synthetic chemists to create organic compounds with diverse structures.
    What are the physical properties of 4-Bromo-2- (Trifluoromethoxy) Benzenethiol?
    4-Bromo-2 - (trifluoromethoxy) thiophenol is one of the organic compounds. Its physical properties are very important and are related to the various applications of this substance.
    First of all, its appearance is mostly colorless to light yellow liquid at room temperature. The characterization of this color state can be one of the important basis for identifying this substance. Looking at its color and shape, we can have a preliminary understanding of its properties.
    Second on its melting point and boiling point. The melting point is the temperature limit of the substance from solid state to liquid state. The melting point of 4-bromo-2 - (trifluoromethoxy) thiophenol is within a certain range, but the exact value may vary depending on the measurement conditions. The same is true for the boiling point, which is the critical temperature for a substance to change from liquid to gas. The boiling point is closely related to the intermolecular forces. The boiling point of this substance reveals the phase transition at which temperature it will undergo, which is of great significance in chemical production, separation and purification.
    Furthermore, its density is also a key physical property. Density, the mass of the substance per unit volume is also. The density of 4-bromo-2 - (trifluoromethoxy) thiophenol determines its fluctuation in a specific environment, and it has an impact on the research, transportation and storage of the mixed system.
    The solubility of this substance cannot be ignored. This substance has a certain solubility in common organic solvents, such as ethanol and ether. In water, its solubility is poor. This property plays an important role in the process of solvent selection and product separation in chemical reactions.
    In addition, its odor is unique. It has a pungent odor. The intensity of this odor is enough to warn people to take appropriate protective measures during operation and use to ensure personal safety.
    In summary, the physical properties of 4-bromo-2 - (trifluoromethoxy) thiophenol, such as appearance, melting point, density, solubility, and odor, are interrelated, which together determine its application scope and operation specifications in the chemical field.
    What is the synthesis method of 4-Bromo-2- (Trifluoromethoxy) Benzenethiol?
    The synthesis of 4-bromo-2 - (trifluoromethoxy) thiophenol is an important research in organic synthetic chemistry. This compound has potential applications in many fields, such as medicinal chemistry, materials science, etc. The synthesis method can be achieved by multi-step reaction.
    The starting material is selected from benzene derivatives containing appropriate substituents, one of which is a bromine atom, and the other is a reagent that can introduce trifluoromethoxy. The first step is to introduce trifluoromethoxy by nucleophilic substitution reaction. In this reaction, it is crucial to select the appropriate base and solvent. The base can promote the formation of nucleophilic species in the reagent, and then replace the halogen atom on the benzene ring. Commonly used bases such as potassium carbonate, sodium carbonate, etc., and the solvent can choose polar aprotic solvents such as N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), which can increase the reaction rate and increase the yield.
    After the introduction of trifluoromethoxy group, the next step is the introduction of thiophenol group. This step is usually achieved by nucleophilic substitution reaction with sulfur-containing reagents, such as sodium hydrosulfide. This reaction condition also needs to be carefully controlled, such as temperature and reaction time. If the temperature is too high, or side reactions occur, the purity and yield of the product are damaged; if the temperature is too low, the reaction rate is slow and the time is too long. In the
    synthesis process, the product of each reaction needs to be separated and purified. Common methods include column chromatography, recrystallization, etc. Column chromatography achieves separation by means of the difference in adsorption and distribution of different compounds in the stationary and mobile phases; recrystallization method uses the change of solubility of compounds in different solvents with temperature to achieve the purpose of purification.
    After the above steps, the target product 4-bromo-2 - (trifluoromethoxy) phenylthiophenol can be obtained. However, the synthesis process requires strict operation and precise control of reaction conditions in order to obtain high-purity and high-yield products, which are suitable for applications in related fields.
    What are the precautions for 4-Bromo-2- (Trifluoromethoxy) Benzenethiol in storage and transportation?
    4-Bromo-2 - (trifluoromethoxy) thiophenol is an important raw material for organic synthesis. During storage and transportation, many matters need to be paid attention to to in order to ensure its quality and safety.
    When storing, the first environment. It should be placed in a cool, dry and well-ventilated place. This compound is heat-resistant and prone to decomposition and deterioration at high temperatures. If the temperature of the storage is too high during hot weather, it may cause chemical reactions and damage its properties. Therefore, the temperature of the warehouse should be controlled within a suitable range, preferably around 20 degrees Celsius, and direct sunlight should be avoided. Light may also cause photochemical reactions to occur, causing changes in ingredients.
    Furthermore, storage containers are essential. It is necessary to use corrosion-resistant materials such as glass or specific plastics. Because of its thiophenol group, it is corrosive to a certain extent, and ordinary metal containers are easily corroded, causing product contamination. The container must be tightly sealed to prevent contact with air. The thiophenol group of this compound is easily oxidized. If exposed to air for too long, it will form sulfone or sulfoxide substances, which will reduce its purity.
    The important thing for transportation is that the packaging is stable. The product must be properly packaged to resist vibration and collision during transportation. If the packaging is not strong and the container is damaged, not only will the product be damaged, but the leakage may endanger the transportation personnel and the environment.
    The transportation conditions must also be appropriate. Do not mix with oxidants, strong alkalis, etc. When this compound encounters oxidizing agents, it is prone to violent oxidation reactions, and there is a risk of fire and explosion. When it encounters strong alkalis, reactions such as acid-base neutralization may occur, which changes its chemical properties. Transportation vehicles should also be kept cool and protected from high temperatures, and equipped with necessary emergency treatment equipment, such as fire extinguishers, adsorption materials, etc., for emergencies.
    What is the market price range for 4-Bromo-2- (Trifluoromethoxy) Benzenethiol?
    4-Bromo-2 - (trifluoromethoxy) thiophenol, which is an important chemical raw material in the field of organic synthesis, is widely used in many fields such as medicine, pesticides and material science. However, its market price range is difficult to sum up, and it is affected by many factors.
    The first to bear the brunt is the market supply and demand situation. If the market demand for 4-bromo-2 - (trifluoromethoxy) thiophenol is strong, but the supply is relatively scarce, if the pharmaceutical industry develops new drugs to increase its usage, resulting in a shortage of supply, its price will rise; on the contrary, if the supply exceeds demand, the price will decline.
    Furthermore, the cost of raw materials has a great impact. The price fluctuation of the basic chemical raw materials required for the synthesis of 4-bromo-2 - (trifluoromethoxy) phenylthiophenol is directly related to the cost of the target product. Raw material prices rise, production costs rise, and product prices will rise; if raw material prices decline, product prices are expected to decrease.
    The production process is also a key factor. Advanced and efficient production processes can improve production efficiency, reduce energy consumption and waste generation, thereby reducing production costs. Prices may be competitive; if the process is backward, production efficiency is low, costs are high, and prices are difficult to reach the people.
    In addition, regional factors cannot be ignored. Different regions have different prices due to different levels of economic development, logistics costs, and market competition. In economically developed areas, the demand may be large, but the competition is fierce, and the price may be relatively reasonable due to competition; in remote areas, the logistics cost is high, the market size is small, and the price may be high.
    Overall, the market price of 4-bromo-2 - (trifluoromethoxy) thiophenol may range from tens to hundreds of yuan per kilogram. The specific price depends on the actual market conditions. If the buyer wants to know the exact price, he can communicate with the relevant chemical product suppliers in detail to obtain an accurate quotation.