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4-Bromo-2-Nitro(Trifluoromethoxy)Benzene

4-Bromo-2-Nitro(Trifluoromethoxy)Benzene

Hongda Chemical

    Specifications

    HS Code

    474085

    Chemical Formula C7H3BrF3NO3
    Molar Mass 299.999 g/mol
    Appearance Solid (predicted)
    Solubility In Water Insoluble (predicted)
    Logp 3.89 (predicted)

    As an accredited 4-Bromo-2-Nitro(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - bromo - 2 - nitro(trifluoromethoxy)benzene in a sealed chemical - grade bottle.
    Storage 4 - bromo - 2 - nitro(trifluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Label the container clearly to avoid mix - ups.
    Shipping 4 - bromo - 2 - nitro(trifluoromethoxy)benzene is shipped in well - sealed, corrosion - resistant containers. Shipment follows strict chemical transportation regulations, ensuring safety during transit to prevent any leakage or hazard.
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    4-Bromo-2-Nitro(Trifluoromethoxy)Benzene 4-Bromo-2-Nitro(Trifluoromethoxy)Benzene
    General Information
    Historical Development
    4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene is also an organic compound. Its origin can be traced back to the evolution of chemical research. In the early days, chemists focused on basic organic synthesis. With the accumulation of knowledge and technological innovation, the exploration of such halogen-containing, nitro and special oxygen compounds became deeper.
    In the past, synthesis methods were limited and it was difficult to obtain raw materials. However, chemists adhered to the spirit of research and tried repeatedly to find a way to prepare this compound. At first, the yield was quite low and the purity was not good. After numerous improvements, the reaction conditions were optimized, and suitable catalysts were selected, the synthesis efficiency and quality were significantly improved. The development of this compound has witnessed continuous breakthroughs in the field of chemistry, from ignorance to mastery, adding a wonderful chapter to organic synthetic chemistry, and gradually developing important uses in many fields such as materials science and drug research and development.
    Product Overview
    4-Bromo-2-nitro (trifluoromethoxy) benzene is a kind of organic compound. Its shape may be colorless to pale yellow liquid with a special odor. This compound is widely used in the field of organic synthesis.
    In its structure, bromine atoms, nitro groups and trifluoromethoxy groups are all connected to the benzene ring. Bromine atoms are active and can participate in many reactions such as nucleophilic substitution; nitro groups have strong electron absorption, which affects the electron cloud distribution and reactivity of molecules; trifluoromethoxy groups endow compounds with unique physical and chemical properties.
    Synthesis of this compound often requires careful design of the reaction path, selection of suitable reagents and reaction conditions. When preparing, temperature, pH and other factors need to be strictly controlled to ensure the smooth progress of the reaction and improve the purity and yield of the product.
    This compound has promising prospects in the fields of medicine, pesticides and materials science. In pharmaceutical research and development, it may lay the foundation for the creation of new drugs; in the field of pesticides, it may help develop efficient and low-toxicity pesticide varieties; in materials science, it may be used as a key intermediate for the synthesis of materials with special properties.
    Physical & Chemical Properties
    4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, it may be solid at room temperature, and its color may be light yellow. Melting point and boiling point are both certain, depending on their physical state changes. The solubility is different from that of different solvents. In organic solvents or with considerable solubility, it is slightly soluble in water.
    In terms of its chemical properties, it is quite active because it contains functional groups such as bromine, nitro and trifluoromethoxy. Bromine atoms can undergo substitution reactions and are easily replaced by nucleophiles. Nitro has strong electron-absorbing properties, which affect the electron cloud distribution of molecules, reducing the electron cloud density of the benzene ring and causing the activity of the electrophilic substitution of the benzene ring to decrease. The presence of trifluoromethoxy also affects the stability and reactivity of molecules, or changes the polarity of compounds. These physical and chemical properties are widely used in organic synthesis and other fields.
    Technical Specifications & Labeling
    Today there is a product called 4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene. In my chemical research industry, the process specification and identification (commodity parameters) are the key.
    To make this product, the process specification needs to be rigorous. From the selection of raw materials, the precision of the ratio, to the temperature and time control of the reaction, all cannot be ignored. First take the appropriate material, mix it in a certain proportion, and react at a specific temperature. The process must be carefully checked to prevent errors.
    The identification (commodity parameters) cannot be ignored. Its materialization properties, such as color, state, and melting point, should be detailed. And its purity geometry and a number of impurities are all important for identification. These two, process regulations and identification (commodity parameters), are the top priority in the research, production and sale of 4-Bromo-2-Nitro (Trifluoromethoxy) Benzene, and cannot be ignored.
    Preparation Method
    4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene is an important organic compound. The raw material selection is crucial for its preparation. The initial reactants containing bromine, nitro and trifluoromethoxy groups can be selected.
    Preparation process requires careful planning of the reaction steps. First, the bromine-containing compound is reacted with a specific reagent to introduce nitro groups. This step requires strict control of the reaction conditions, such as temperature, pressure and reaction time. Then, the trifluoromethoxy group is ingeniously inserted.
    During the reaction process, pay close attention to the progress of each step of the reaction. Use appropriate monitoring methods, such as chromatographic analysis, to ensure that the reaction proceeds as expected. And a reasonable catalytic mechanism should be constructed to accelerate the reaction rate and increase the yield.
    Through such raw material selection, process design, step response and catalytic assistance, it is expected to efficiently prepare 4-Bromo-2-Nitro (Trifluoromethoxy) Benzene.
    Chemical Reactions & Modifications
    4-Bromo-2-Nitro (Trifluoromethoxy) Benzene is a crucial compound in organic synthesis. The chemical reactions involved in its synthesis need to be precisely controlled at every step.
    In the reaction of synthesizing this compound, factors such as the ratio of reactants, reaction temperature and time have a great impact on the purity and yield of the product. In the initial reaction step, the mixing of raw materials needs to be uniform, and the temperature regulation is slightly poor, which will cause the reaction rate to change and even form by-products.
    The key to improvement is to optimize the reaction conditions. After many experiments, moderately increasing the reaction temperature and precisely adjusting the ratio of reactants can significantly improve the yield of the product. At the same time, screening efficient catalysts can also speed up the reaction process and reduce the occurrence of side reactions. In this way, high-quality synthesis of 4-Bromo-2-Nitro (Trifluoromethoxy) Benzene can be achieved, laying a solid foundation for subsequent research and application.
    Synonyms & Product Names
    4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene, the same thing. Its trade name is the same, and it is important in the field of chemistry.
    The same name, or the same name, represents the same thing in different ways. For things, there may be another name according to their characteristics. This is because there are many names for different things, and different people or according to different names, so the same name is born.
    As for the trade name, it is the name taken by the merchant for their products. Either seeking easy or showing its characteristics to facilitate market promotion. However, the same or trade name refers to this 4-Bromo-2-Nitro (Trifluoromethoxy) Benzene. Our researchers can only get the whole picture by exploring the properties and uses of this object, and by distinguishing its same trade name.
    Safety & Operational Standards
    4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene Safety and Operation Specifications
    Husband 4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene is also a research object. Its properties are special, so safe operation is of paramount importance.

    For the purpose of storage, it is appropriate to make things dry, dry, and good places. Do not place oxidizing or raw materials in the same place to prevent the reaction of dangerous plants. Oxidation and raw materials are very active. When this compound encounters, it is afraid of ignition and explosion.
    For operation, you must use anti-clothing, wear anti-protective gloves and eyes. If this compound is exposed to the skin, or causes skin damage; if it enters the eye, it will be more harmful, or it may cause damage. Operation is normal, so that it can be discharged and avoided in the room, endangering the operator.
    Furthermore, the use of this compound depends on the operating procedure. There should be no difference in the amount, dissolution or reverse step. If the reverse part is not controlled, such as the degree and force do not meet the requirements, it may also cause accidents.
    Once there is a leakage, do not panic. First, quickly evacuate the surrounding area and isolate the area. That is, the leakage is adsorbed with the same material, and it should not be allowed to disperse. Clean-up materials and leaks should be properly disposed of according to regulations, and should not be disposed of intentionally to avoid contaminating the environment.
    Of course, 4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene has its uses in chemical research, but the operator must keep safe and operate in order to ensure their own safety and the safety of the environment.
    Application Area
    Today there is a product called 4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene. This product has its uses in various fields.
    In the field of medicine, it may be the key raw material for the creation of new agents. With its special structure, it can help doctors develop cures and cure diseases.
    In the field of materials, it can participate in the synthesis of exquisite materials. Through ingenious methods, the material is given unique properties, whether strong or tough, or with specific optical and electrical properties, which are suitable for the needs of all kinds of high-tech materials.
    As for agricultural use, it is also possible. Or it can assist in the research of new pesticides, protect the harvest, repel insects and diseases, and ensure the hope of a bumper harvest. This is the scope of 4-Bromo-2-Nitro (Trifluoromethoxy) Benzene, which can be used in this world. Its power cannot be underestimated.
    Research & Development
    Today, we are studying 4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene, which has different properties and a wide range of uses. Yu and others have worked hard to explore its preparation method and analyze its structural characteristics. After repeated tests, the process has been improved to improve the yield and optimize the quality.
    Looking at the research process, the initial difficulties are many, and the ratio of raw materials and reaction conditions need to be fine-tuned. However, the team is united, not afraid of difficulties, repeated consideration, and finally a delicate method. When preparing, temperature, duration, and catalyst dosage are all key, and if there is a slight difference, the results will be very different.
    Looking forward to its development, this product has potential in many fields. Or it can be used to create new drugs, with its unique structure, acting on specific targets; or it can be applied to high-tech materials to improve material properties. We should continue to study and expand its applications, promote progress in this field, and contribute to the development of science, so that the effectiveness of 4-Bromo-2-Nitro (Trifluoromethoxy) Benzene can be fully realized.
    Toxicity Research
    Today, there is a substance, named 4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene. We take toxicological research as our service to investigate its toxicity in detail. The structure of this substance is unique, and the coexistence of bromine, nitro and trifluoromethoxy may cause it to have special toxicological properties.
    Experiments have found that it may be potentially harmful to organisms. At the cellular level, it may affect the metabolism and proliferation of cells, causing cell physiological dysfunction. And its chemical activity may cause changes in the structure and function of biological macromolecules such as proteins and nucleic acids, endangering life-threatening activities.
    The nature of toxicants also depends on the dose. When carefully exploring the effects of different doses on various organisms to clarify their safety thresholds. This research is relevant to people's livelihood and the environment, and it is necessary to conduct a rigorous investigation in order to obtain the truth about poisons and provide evidence for protection and treatment.
    Future Prospects
    Prospects of the future, in 4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene, this product is the product of the future. Its characteristics are not special, or it can be used in the field of the new way. If it can be refined to study its chemical properties, or it can be made into special effects, it can cure general diseases, and save lives and pains.
    And in the field of materials, it is also expected to greatly expand the color.
    Its special design, or it can be developed into new materials, used in aerospace, electronics and other aspects, to promote the progress of science and technology.
    If you want to create this situation, you must make unremitting efforts. Study its principles, explore its principles in depth, and seek new results with the method of science. In this way, 4 - Bromo - 2 - Nitro (Trifluoromethoxy) Benzene can be used to achieve great success and create a blessing for generations.
    Where to Buy 4-Bromo-2-Nitro(Trifluoromethoxy)Benzene in China?
    As a trusted 4-Bromo-2-Nitro(Trifluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-2-Nitro(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Bromo-2-Nitro (Trifluoromethoxy) Benzene?
    4-Bromo-2-nitro (trifluoromethoxy) benzene has a wide range of uses. In the field of organic synthesis, it is often a key intermediate. It can be derived from a variety of compounds through a series of chemical transformations.
    First, in the field of pharmaceutical creation, this is used as the starting material. After delicate reaction steps, it may be able to construct a molecular structure with specific biological activities, providing the possibility for the development of new drugs. Due to the existence of bromine, nitro and trifluoromethoxy in its structure, it gives it unique chemical properties and spatial characteristics, or it can be precisely matched with biological targets, thereby demonstrating therapeutic efficacy.
    Second, in the field of materials science, it also has important value. It can be integrated into polymer materials through polymerization or modification to change the electrical, optical or thermal properties of the materials. For example, in optoelectronic materials, its special structure or can adjust the charge transport performance and luminous efficiency of the material, which contributes to the preparation of new optoelectronic devices.
    Furthermore, in the field of pesticide chemistry, compounds created on this basis may have good biological activities, such as insecticidal, bactericidal or herbicidal effects. Due to the combination of bromine, nitro and trifluoromethoxy, the interaction between the compound and the target in the body of pests, bacteria or weeds can be optimized, and the effect and selectivity of pesticides can be improved.
    In summary, 4-bromo-2-nitro (trifluoromethoxy) benzene is an indispensable and important compound in many fields such as organic synthesis, medicine, materials and pesticides, and plays a pivotal role in the development process of various fields.
    What are the physical properties of 4-Bromo-2-Nitro (Trifluoromethoxy) Benzene?
    4-Bromo-2-nitro (trifluoromethoxy) benzene is a kind of organic compound. Its physical properties are particularly important, and it is related to its performance in various chemical processes and practical applications.
    First, its appearance, under normal conditions, or in a light yellow to light brown crystalline powder shape, this morphology is easy to observe and preliminary identification.
    times and melting point, about a certain temperature range, this characteristic can be used as a key basis for the purity identification and separation and purification of compounds. The melting point of the compound with different purity may be deviated, and its purity can be distinguished by this.
    The boiling point is also one of the important physical properties. In a specific pressure environment, when a certain temperature is reached, the substance changes from liquid to gaseous state. The value of the boiling point is of great significance for separation operations such as distillation, which can help chemists to effectively separate this compound from the mixed system according to different boiling points.
    Furthermore, its solubility cannot be ignored. In organic solvents such as dichloromethane and chloroform, it has good solubility. This property makes the compound well dispersed in the reaction system in the organic synthesis reaction and promotes the progress of the reaction. However, in water, the solubility is not good. This difference helps to take advantage of the stratification characteristics of the aqueous phase and the organic phase to perform separation methods such as extraction.
    In addition, the density of the compound is higher than that of water, and its location can be determined according to the density difference in operations involving liquid-liquid separation.
    The above physical properties are interrelated, and chemists can use them to accurately design and control chemical reactions and properly handle compounds. It is of great guiding value in many fields such as organic synthesis and materials science.
    Is 4-Bromo-2-Nitro (Trifluoromethoxy) Benzene Chemically Stable?
    The chemical properties of 4-bromo-2-nitro (trifluoromethoxy) benzene are still stable in common sense. In this compound, bromine atoms, nitro groups and trifluoromethoxy groups are controlled by each other according to their positions.
    Bromine atoms have certain substitution activity, but the surrounding nitro groups and trifluoromethoxy groups restrict their activity. Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and make it difficult for electrophilic substitution reactions to occur. However, under certain conditions, it may trigger nucleophilic substitution reactions. Trifluoromethoxy is also an electron-absorbing group, which further affects the electron cloud distribution of the benzene ring and enhances the stability of the molecule.
    This compound can maintain its structural stability in the absence of strong external chemical action, such as high temperature, strong acid and base, strong oxidizing agent or reducing agent. In the context of organic synthesis, although each group has potential reactivity, due to its interaction, in order to make it undergo a specific reaction, the reaction conditions need to be carefully regulated, such as precise selection of reaction reagents, temperature, solvents and other factors, in order to achieve the expected transformation. In general, the chemical properties of 4-bromo-2-nitro (trifluoromethoxy) benzene are relatively stable in the general environment, but in the delicate field of organic chemistry, it has abundant reaction possibilities, which need to be carefully explored and regulated.
    What are the preparation methods of 4-Bromo-2-Nitro (Trifluoromethoxy) Benzene?
    The method of preparing 4-bromo-2-nitro (trifluoromethoxy) benzene has been explored by many people in the past, but now it is the first method.
    One method is to use 4-bromo-2-nitrophenol as the starting material. This phenol is first reacted with a trifluoromethylated reagent, such as trifluoromethylsulfonic anhydride (Tf ² O), in the presence of a suitable base, such as potassium carbonate (K ² CO 🥰), in an aprotic solvent, such as N, N -dimethylformamide (DMF). The base can take away the hydrogen of the phenolic hydroxyl group to form a phenoxy negative ion. This negative ion nucleophilic attacks the trifluoromethoxy part of the trifluoromethylation reagent, thereby introducing the trifluoromethoxy group to obtain the target product. When reacting, pay attention to the temperature control, not too high, so as to avoid the growth of side reactions.
    The second method starts from 2-nitro-4- (trifluoromethoxy) aniline. First, the aniline is diazotized at a low temperature, about 0-5 ° C, with appropriate diazotization reagents, such as sodium nitrite (NaNO ²) and hydrochloric acid (HCl), to form diazonium salts. Then, the solution of hydrobromic acid (HBr) of cuprous bromide (CuBr) is added, and the Sandmeyer reaction occurs. The diazo group is replaced by a bromine atom, and 4-bromo-2-nitro (trifluoromethoxy) benzene is obtained. During this process, the low temperature and the acidity of the reaction solution need to be carefully adjusted to ensure a smooth reaction.
    There are also those who use 4-bromo-2-nitrobenzoic acid as the starting material. First, the carboxyl group is converted into a group that is easy to leave, such as methyl ester. Then, under the action of a strong base, such as sodium hydride (NaH), it reacts with a trifluoromethylating agent to introduce a trifluoromethoxy group. Then, the target product can be obtained through the reduction and decarboxylation step. However, there are many steps in this path, and the reaction conditions of each step need to be optimized in detail to improve the yield.
    All production methods have their own advantages and disadvantages, and are suitable for industrial production or laboratory preparation. It should be carefully selected according to factors such as the availability of raw materials, cost and difficulty of reaction conditions.
    What is the price range of 4-Bromo-2-Nitro (Trifluoromethoxy) Benzene in the market?
    4-Bromo-2-nitro (trifluoromethoxy) benzene, the price of this substance in the market is difficult to determine. The range of its price often varies for a variety of reasons.
    First, the method and difficulty of preparation are related to its price. If the preparation process is complicated, rare raw materials are required, or the reaction conditions are strict, such as precise temperature control, pressure control, and high requirements for equipment, the cost will increase, and the price will also be high. On the contrary, if the production method is simple and the raw materials are common, the price may be slightly lower.
    Furthermore, the state of supply and demand has a great impact. If there is a strong demand for this product in the market, but the supply is limited, if there is a sharp increase in demand for this product in a certain industry, it will be difficult for producers to supply it in sufficient quantities in a timely manner, and the price will rise; if the demand is sluggish and the manufacturer produces too much, the market will be flooded with this product. In order to make a sale, the price may be reduced.
    Also, the quality is related to the price. High-quality products have less impurities and high purity, and have more advantages in special applications, and the price must be higher than those with slightly inferior quality.
    In addition, the state of market competition also plays a role. If multiple factories produce this product, the competition is fierce, in order to occupy the market share, or some manufacturers reduce the price to promote; if the market is monopolized by a few manufacturers, the price is easy to
    In the past, the price of this chemical per gram may range from tens to hundreds of yuan. However, this is only an approximation, and the actual price should be based on the current market conditions, merchant pricing and transaction volume. If the purchase volume is very large, the merchant may give a discount, and the price may be lower; if the purchase volume is rare, plus other costs, the price per gram may be higher.