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4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene

4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    917200

    Chemical Formula C7H3BrF3NO2
    Molar Mass 286.003 g/mol
    Appearance Typically a solid
    Melting Point Data may vary by source
    Boiling Point Data may vary by source
    Density Data may vary by source
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
    Flash Point Data may vary by source
    Vapor Pressure Low vapor pressure
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

    As an accredited 4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4 - bromo - 2 - nitro - 1 - (trifluoromethyl)benzene in sealed chemical - grade containers.
    Storage 4 - bromo - 2 - nitro - 1 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent vapor leakage. Due to its potential hazards, ensure storage is in a location inaccessible to unauthorized personnel and in compliance with safety regulations.
    Shipping 4 - bromo - 2 - nitro - 1 - (trifluoromethyl)benzene is shipped in sealed, corrosion - resistant containers. Compliance with hazardous chemical shipping regulations is ensured, with proper labeling for safe transportation.
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    4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene 4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    4-Bromo-2-nitro-1- (trifluoromethyl) benzene, a new product of chemistry. Watching the evolution of chemistry, the sages of the past dynasties have devoted themselves to exploring physical properties and innovating techniques. The initial appearance of this product has also been studied in various ways.
    In the past, chemists were deeply cultivated in the field of organic synthesis. Begin with basic raw materials, according to the principles of chemistry, exquisite operation. After many experiments, adjusting its conditions and controlling its reactions, the embryonic form of this compound was obtained.
    After the scholars, they carried on the work of their predecessors and strived for excellence. Optimize the synthesis method, improve the yield and improve the purity. Or in the reaction medium, or in the catalytic agent, careful study has finally made 4-bromo-2-nitro-1- (trifluoromethyl) benzene, from its initial state, gradually complete, in chemical applications, emerging, laying the foundation for future development.
    Product Overview
    Product Overview
    4-Bromo-2-nitro-1- (trifluoromethyl) benzene is a crucial compound in the field of organic synthesis. It has a unique chemical structure. Bromine atoms, nitro groups and trifluoromethyl are cleverly arranged based on benzene rings, giving the substance many special physical and chemical properties.
    This compound usually has a white to light yellow crystalline powder appearance, suitable melting point, and has good solubility in specific organic solvents. Due to its structure containing strong electron-absorbing nitro and trifluoromethyl groups, it is chemically active and often used as a key intermediate. It is widely used in medicine, pesticides and materials science.
    In the field of pharmaceutical synthesis, with its active chemical activity, complex structures with biological activity can be constructed through a series of reactions such as nucleophilic substitution and reduction, providing an important foundation for the research and development of new drugs. In the field of pesticide creation, it can participate in the synthesis of compounds with high insecticidal, bactericidal or herbicidal properties, contributing to the sustainable development of agriculture. In the field of materials science, its special structure may improve the electrical and optical properties of materials and promote the innovation of advanced materials.
    Physical & Chemical Properties
    4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene is an organic compound. Its physical properties are solid at room temperature, and its color may be light yellow. The melting point is in a specific range, because accurate determination requires experimental operation. The substance is insoluble in water, but soluble in some organic solvents, such as ethanol, ether, etc. This property is derived from its molecular structure.
    In terms of chemical properties, it contains functional groups such as bromine, nitro and trifluoromethyl. Bromine atoms have certain reactivity and can undergo substitution reactions. Nitro is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring and affects the electrophilic substitution reactivity of the benzene ring. Trifluoromethyl is also an electron-withdrawing group, which enhances molecular stability and chemical inertness. Due to the large electronegativity of fluorine atoms, the compound has unique chemical properties and has specific uses in the field of organic synthesis. It can participate in a variety of organic reactions to build complex organic molecular structures.
    Technical Specifications & Labeling
    Today there is a product called 4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene. In this product, the process specifications and identification (commodity parameters) are the key.
    In terms of its process specifications, the preparation method needs to follow a precise formula. The choice of raw materials must be pure and free of impurities, and the temperature, time and pressure of the reaction are all fixed. If a certain method is used, the temperature is controlled at XX degrees, and the initial state can be achieved after XX. The subsequent refining process also needs to follow the specifications to obtain high-quality products.
    As for the identification (commodity parameters), its color, taste and state should be detailed in the book. The color is XX, the taste is XX, and it is XX state under normal circumstances. And its purity, impurity content and other data must be accurately marked to clarify its quality, and the user can make good use of it. This is also the key to process specifications and identification (commodity parameters).
    Preparation Method
    To prepare 4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene, the raw materials and production process, reaction steps and catalytic mechanism are the key. First, take an appropriate amount of fluoroaromatic hydrocarbons, mix them with brominating reagents in a specific ratio, and catalyze the bromination reaction under a suitable temperature and pressure. This step requires precise control of the reaction time and temperature, so that the bromine atom is just at the target check point.
    Then, introduce nitrifying reagents, ingeniously regulate the reaction conditions, and make the nitro group accurately integrate to form a preliminary product. After the reaction is completed, the impurities are removed by separation and purification to obtain a pure product. The entire process, the purity of the raw materials, the temperature of the reaction, and the activity of the catalyst are all crucial to success or failure. Careful operation is required to ensure the quality and yield of this product according to established procedures.
    Chemical Reactions & Modifications
    4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene is an important chemical compound. In the past chemical research, its chemical reaction and modification have always been the focus.
    To obtain this compound, the common reaction path is to take a specific aromatic hydrocarbon as the starting material, through halogenation, nitration and introduction of trifluoromethyl. When halogenating, choose the appropriate halogenation reagent and reaction conditions, so that the bromine atom can be precisely connected to the designated position of the benzene ring. In the nitration reaction, the ratio of mixed acid and temperature are controlled to ensure the smooth introduction of nitro groups at the ortho position. The introduction of trifluoromethyl often requires the help of special fluorine-containing reagents and catalytic systems.
    However, there is still room for improvement in this reaction. First, some reaction conditions are harsh, requiring high equipment and high energy consumption, and mild reaction conditions can be explored to reduce energy consumption and equipment costs. Second, the reaction selectivity may be improved. By developing new catalysts or optimizing reaction solvents, the reaction can be more directional and the generation of by-products can be reduced. In this way, the synthesis of 4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene can be made more efficient and green.
    Synonyms & Product Names
    Today there is a thing called 4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene. This thing is very important in my chemical research. Its nickname and trade name are also the main points of research.
    It is common for scientific research to find its nickname. Cover different names, or due to differences in research angles, or due to differences in regions and habits. Knowing nicknames, you can gather literature and brainstorm. As for trade names, they are related to market circulation, and the names given by different manufacturers may vary.
    The nickname of this thing is either based on its chemical structure characteristics, or according to its reaction characteristics. And trade names often have both practical and marketing meanings. Our chemical researchers need to scrutinize their different names in order to be handy and correct when researching and applying them. In terms of literature review, experimental operation, and market transactions, they can be accurate and promote the research process.
    Safety & Operational Standards
    4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene is an important chemical compound in chemical synthesis. In its experimental preparation and application, safety and operating standards are of paramount importance.
    This compound has certain chemical activity and potential danger. From a safety point of view, first, store in a cool, dry and well-ventilated place away from fire, heat and strong oxidants to prevent the risk of explosion due to violent chemical reactions. Second, when taking it, the experimenter must wear complete protective equipment, such as protective gloves, goggles and laboratory clothes. Because the compound may be irritating and corrosive to the skin and eyes, if it is inadvertently exposed, it should be immediately rinsed with a large amount of water, and seek medical treatment according to the severity of the injury.
    In terms of operation specifications, first of all, it is necessary to accurately plan the experimental process and dosage before the experiment to avoid material waste and danger caused by excessive reaction. During the reaction operation, the reaction conditions, such as temperature, pressure and reaction time, must be strictly controlled. The reaction in which this compound participates may require strict conditions, and a slight deviation may affect the purity and yield of the product, or even cause accidents. Secondly, the exhaust gas, waste liquid and waste residue during the experiment should be properly disposed of. The waste gas needs to be effectively purified and discharged, and the waste liquid and waste residue should be collected according to their chemical properties, and handed over to professional institutions for harmless disposal. It must not be dumped at will to avoid polluting the environment.
    When performing various operations related to 4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene, strictly abide by safety and operating standards to ensure the smooth progress of the experiment, and at the same time ensure the safety of the experimenter and the environment.
    Application Area
    4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene is also a chemical product. Its application field is not good. In the field of synthesis, it can be used in the middle and assist in research and development, so that the effect can be improved. With its characteristics, it may be able to create specific chemical molecules and cure general diseases.
    In the field of materials, it is also useful. It can help synthesize special materials and improve the novelty of materials, such as increasing their quality and improving their optics. Make the material effective in materials, optical equipment, etc., and promote the progress of science and technology.
    In addition to research, this product may help. It can be used as raw materials to produce high-efficiency products, eliminate pests, reduce crops, and ensure good harvests, which is of great benefit to people's livelihood.
    Research & Development
    There is now a product named 4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene. As a chemical researcher, I often study the properties, preparation methods and applications of this product, hoping to make progress in research and development.
    At first, its properties were explored, and it was known that it had a special chemical structure, and the order of bromine, nitro and trifluoromethyl gave it unique reactivity. This structure is used in the field of organic synthesis, or is a key intermediate, and can lead to various reactions to form various compounds.
    As for the preparation method, after repeated tests, several paths were obtained. Or starting from a specific aromatic hydrocarbon, through halogenation, nitrification and trifluoromethylation, etc. Although the advantages and disadvantages of each method are mutually exclusive, after optimization, it is expected to obtain efficient and pure products.
    Talking about applications, it can be used in pharmaceutical research and development, or it can be used as a lead compound. After structural modification, molecules with specific biological activities can be obtained, which will contribute to the creation of new drugs. In materials science, or because of its special structure, it can endow materials with novel properties, such as improving the stability and solubility of materials.
    We should continue to study and dig deep into the potential of this substance, hoping to make more breakthroughs in the process of research and development, and contribute to the progress of the chemical field.
    Toxicity Research
    Since modern times, chemical refinement has made all kinds of compounds increasingly apparent in the world. Today there is 4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene, and the study of its toxicity is a top priority.
    Watching the signs of toxicity, or involving the body of living beings, damages its internal organs and disrupts its physiology. In the cells of the micro, or disturb its metabolism and destroy its structure. Although the shape of this thing is either colorless crystal or clear liquid, its potential danger cannot be ignored.
    If you want to study its toxicity, you should use scientific methods to conduct experiments. Take the animal as a model, observe its state after taking this thing, and observe the changes in its behavior and the differences in body symptoms. It is also necessary to study the path of its entry into the body, either by breathing, or by eating, each has a different effect.
    Furthermore, in the environment, the dispersion of this thing, or sewage soil, or air pollution, endangers the surrounding organisms. It is a study of toxicity, which is related to the safety of living beings and the peace of the environment, and cannot be ignored. It is necessary to investigate in detail and explain the reason for its poison, so as to prevent problems before they occur and protect the health of all things.
    Future Prospects
    Fu 4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene, a new product of chemical engineering. Its undeveloped development can be looked forward to.
    In the field of engineering, this product may be the foundation of a new process. Its special design, or lead to the innovation of material science. Due to its characteristics, it can be used in the manufacture of special plastics and materials to make it have excellent performance, weather resistance, and resistance.
    The way of development is also promising. Or the first research of new research, its chemical properties, specific diseases, and special effects.
    And scientific exploration, this product may be a new way of anti-chemical research. Helpers deepen the secrets of understanding and expand the boundaries of knowledge. Unknown, 4 - Bromo - 2 - Nitro - 1 - (Trifluoromethyl) Benzene will unleash its colors in multiple fields, becoming a help for technology.
    Where to Buy 4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene in China?
    As a trusted 4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Bromo-2-Nitro-1- (Trifluoromethyl) Benzene?
    4-Bromo-2-nitro-1- (trifluoromethyl) benzene has a wide range of uses in the field of organic synthesis. First, it is a raw material for the preparation of pharmaceutical intermediates. When creating antibacterial, anti-cancer and other drugs, this compound can be added with specific functional groups through various chemical reactions due to its unique structure, and gradually build a complex molecular structure with biological activity, making it a key starting material for pharmaceutical synthesis.
    Second, it also has important functions in the field of pesticides. Through a series of organic transformations, it can produce highly efficient pesticides, fungicides and other pesticide products. Its fluorine, bromine and nitro structure can endow pesticides with better biological activity and stability, and has remarkable results in the control of crop diseases and pests.
    Furthermore, in the field of materials science, it can be used as a building block for the synthesis of special functional materials. For example, when preparing polymer materials with specific optical and electrical properties, the introduction of this compound structural unit may endow the material with special photoelectric properties, opening up a path for the research and development of new functional materials.
    In addition, in dye chemistry, it can participate in the synthesis of dyes with unique colors and properties. By modifying its structure, the absorption and emission spectra of dyes can be regulated to meet different dyeing needs.
    All of this highlights the important uses of 4-bromo-2-nitro-1- (trifluoromethyl) benzene in various fields such as organic synthesis, medicine, pesticides, materials and dyes, and is an indispensable basic raw material for the development of the chemical industry.
    What are the physical properties of 4-Bromo-2-Nitro-1- (Trifluoromethyl) Benzene?
    4-Bromo-2-nitro-1- (trifluoromethyl) benzene is one of the organic compounds. It has specific physical properties and is quite used in chemical synthesis and other fields.
    Looking at its properties, under normal temperature, this substance is mostly in a solid state. Its melting and boiling point is quite critical, with a melting point of about [specific value] ° C and a boiling point of about [specific value] ° C. Such boiling point characteristics enable the substance to maintain its corresponding physical form within a specific temperature range, and can provide a certain temperature reference for operation in various chemical reactions and industrial processes.
    In terms of solubility, it exhibits different solubility conditions in organic solvents. In common organic solvents such as dichloromethane, chloroform, etc., there is a certain solubility, but in water, the solubility is extremely limited. This difference in solubility can be used as an important consideration when chemical separation, purification and reaction system construction. By choosing a suitable solvent, the reaction process can be optimized and the purity of the product can be improved.
    Density is also one of its important physical properties, about [specific value] g/cm ³. This density characteristic is not only related to the weight and volume relationship of the substance itself, but also has guiding significance in chemical production, storage and transportation. Accurately knowing its density can help to rationally plan the capacity of the storage container and ensure the safety of the transportation process.
    Furthermore, its appearance may be white to light yellow powder or crystalline. This appearance feature can provide an intuitive basis for preliminary judgment in the process of substance identification. In combination with other analytical methods, such as infrared spectroscopy, nuclear magnetic resonance, etc., the structure and purity of the substance can be accurately confirmed.
    In summary, the physical properties of 4-bromo-2-nitro-1 - (trifluoromethyl) benzene, such as melting point, solubility, density and appearance, play an important role in organic chemistry research, chemical production and related fields of practice, and need to be carefully considered for scientific and industrial applications.
    What are the synthesis methods of 4-Bromo-2-Nitro-1- (Trifluoromethyl) Benzene?
    There are several common methods for synthesizing 4-bromo-2-nitro-1- (trifluoromethyl) benzene.
    One is a benzene derivative containing trifluoromethyl as the starting material. First, bromine atoms are introduced into the benzene ring, and a bromination reaction can be used. If benzene containing trifluoromethyl is reacted with bromine elemental substance in the presence of a suitable catalyst, such as iron powder or iron tribromide, the bromine atom can selectively replace the hydrogen atom at a specific position on the benzene ring to obtain a benzene derivative containing bromine and trifluoromethyl. Then, the derivative is nitrified. The mixed acid of concentrated nitric acid and concentrated sulfuric acid is used as the nitrifying reagent. Under suitable temperature and reaction conditions, the nitro group is introduced into the benzene ring, and the nitro group can be substituted at a specific position according to the localization effect of the existing substituents on the benzene ring, so as to obtain 4-bromo-2-nitro-1- (trifluoromethyl) benzene.
    Second, the nitrobenzene derivative can also be used as the starting material. First, the bromination reaction of nitrobenzene is carried out, and the bromine atom is introduced into the benzene ring with a suitable brominating reagent and catalyst. Then, trifluoromethyl is introduced into the benzene ring by There are many methods for introducing trifluoromethyl. For example, trifluoromethyl-containing reagents, such as Grignard reagents such as trifluoromethyl halide, can be used to undergo nucleophilic substitution reaction with bromonitrobenzene under suitable reaction conditions, and trifluoromethyl can be successfully introduced into the benzene ring. The final product is 4-bromo-2-nitro-1- (trifluoromethyl) benzene.
    Or starting from bromobenzene derivatives, the introduction of nitro groups on bromobenzene first, and then the introduction of trifluoromethyl into the benzene ring through suitable reaction conditions and reagents, which is also a feasible synthetic path. In the actual synthesis process, it is necessary to comprehensively consider and select the most suitable synthesis method according to many factors such as the availability of raw materials, the difficulty of controlling the reaction conditions, and the yield.
    4-Bromo-2-Nitro-1- (Trifluoromethyl) Benzene What to watch out for when storing and transporting
    4-Bromo-2-nitro-1- (trifluoromethyl) benzene is also an organic compound. During storage and transportation, many matters must not be ignored.
    First words storage. This compound may be more active in nature and should be placed in a cool, dry and well-ventilated place. Avoid direct sunlight, which can cause photochemical reactions and damage its quality. Temperature also needs to be controlled. If it is too high, the molecular movement will intensify, or cause adverse reactions such as decomposition and polymerization. Humidity is also the key. If the humidity is too high, water vapor may interact with it and cause it to deteriorate. And should be stored separately from oxidizing agents, reducing agents, alkalis, etc., because the compound structure contains bromine, nitro, trifluoromethyl and other functional groups, encounter with the above substances, or react violently, and risk safety.
    As for transportation, be sure to ensure that the packaging is in good condition. Containers should be strong and resistant to vibration and collision to prevent leakage. During transportation, a suitable environment should also be maintained to prevent sudden changes in temperature and humidity. Transportation vehicles should be selected for compliance and equipped with necessary emergency treatment equipment and protective equipment. Escort personnel must be familiar with the characteristics of the compound and emergency treatment methods. In case of emergencies, they can respond quickly to ensure the safety of personnel and the environment.
    In conclusion, when storing and transporting 4-bromo-2-nitro-1- (trifluoromethyl) benzene, care must be taken in terms of environment, packaging, personnel, etc. to avoid danger and ensure its safety.
    What is the environmental impact of 4-Bromo-2-Nitro-1- (Trifluoromethyl) Benzene?
    4-Bromo-2-nitro-1- (trifluoromethyl) benzene, its impact on the environment is worth exploring. This substance has bromine, nitro and trifluoromethyl groups, and its characteristics are different.
    First of all, its chemical stability is greatly increased due to the presence of trifluoromethyl. This structure is difficult to decompose by common chemical processes in the natural environment and is easy to retain for a long time. If it flows into water bodies, it is hydrophobic or adsorbed on suspended particles, deposited on the bottom of the water, and gradually accumulated in the bottom mud, affecting the aquatic ecology. In soil, it is also difficult to degrade, or change soil chemical properties, affecting vegetation growth.
    Furthermore, its biological toxicity cannot be underestimated. The presence of bromine and nitro groups may make this substance toxic to a certain extent. After biological uptake, it may interfere with cellular physiological processes. For example, nitro groups can be biotransformed to generate active intermediates with strong oxidizing properties, which damage biological macromolecules in cells, such as DNA and proteins, and affect the normal growth, development and reproduction of organisms.
    Re-examine its impact on the atmospheric environment. Although it is not highly volatile at room temperature, it may evaporate into the atmosphere under certain conditions, such as high temperature or industrial processes. In the atmosphere, or participate in photochemical reactions, affect the chemical balance of the atmosphere, and have a potential impact on air quality.
    And it is transmitted and enriched in the environment or through the food chain. After ingestion by lower organisms, due to difficult metabolism and excretion, it rises with the food chain, and the concentration in higher organisms gradually increases, which may eventually endanger human health. Therefore, the situation of such compounds in the environment should be carefully studied to prevent them from causing harm to the ecological environment and human well-being.