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4-Bromo-2-Methy-1-(Difluoromethoxy)Benzene

4-Bromo-2-Methy-1-(Difluoromethoxy)Benzene

Hongda Chemical

    Specifications

    HS Code

    730274

    Chemical Formula C8H7BrF2O
    Molecular Weight 239.04
    Appearance Colorless to light yellow liquid (estimated)
    Solubility In Water Insoluble (aromatic and fluorinated ethers are generally hydrophobic)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (general property of aromatic compounds)
    Stability Stable under normal conditions, but may react with strong oxidizing agents

    As an accredited 4-Bromo-2-Methy-1-(Difluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - bromo - 2 - methyl - 1 - (difluoromethoxy)benzene in sealed chemical - grade bottle.
    Storage 4 - bromo - 2 - methyl - 1 - (difluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials like glass, to prevent leakage and maintain its chemical integrity. Label clearly for easy identification.
    Shipping 4 - bromo - 2 - methyl - 1 - (difluoromethoxy)benzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict chemical transportation regulations, ensuring safety during transit to prevent spills and environmental hazards.
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    4-Bromo-2-Methy-1-(Difluoromethoxy)Benzene 4-Bromo-2-Methy-1-(Difluoromethoxy)Benzene
    General Information
    Historical Development
    4 - Bromo - 2 - Methy - 1 - (Difluoromethoxy) Benzene is also an organic compound. Although its founding period is difficult to study in detail, the evolution of chemical technology is closely related to the prosperity of this thing. In the past, chemists were in the field of organic synthesis, and they worked hard to explore the hidden. In the beginning, the synthesis of all kinds of compounds relied on simple methods, but the effect was not yet achieved. As science gradually became more and more advanced, new technologies became more and more advanced, and the technology of organic synthesis became more and more advanced. 4 - Bromo - 2 - Methy - 1 - (Difluoromethoxy) Benzene also gradually obtained the method of synthesis due to the ingenuity and research of chemists. Its production method is improving, and its yield is increasing day by day. It is increasingly widely used in medicine, materials, and other industries. It has become an indispensable quality in the field of chemistry, and has made great contributions to human well-being. Its future development is also limitless.
    Product Overview
    Today there is a substance called 4 - Bromo - 2 - Methy - 1 - (Difluoromethoxy) Benzene. This is an organic compound with a unique structure. The bromine atom, methyl group and difluoromethoxy group are based on the specific positions of the benzene ring.
    Looking at its physical properties, it is in a liquid state at room temperature, with a specific color, taste and density. Its melting and boiling point is also fixed, which varies depending on the forces between molecules. Chemical properties, the benzene ring gives it the versatility of aromatic compounds, which can undergo electrophilic substitution reactions. Bromine atoms are quite active and can participate in many substitution and elimination reactions. Methyl affects the electron cloud distribution of molecules and changes their reactivity. The presence of difluoromethoxy adds its unique chemical activity, or plays a key role in some reactions.
    This compound is widely used in the field of organic synthesis, or is an important intermediate for the preparation of complex drugs and functional materials, and contributes to chemical research and industrial production.
    Physical & Chemical Properties
    4-Bromo-2-methyl-1- (difluoromethoxy) benzene is also an organic compound. Its physical and chemical properties are worth studying. Looking at its physical properties, at room temperature, or in a liquid state, it has a specific color, taste and phase state. Its boiling point, melting point, etc. are the keys to characterize its physical properties. The boiling point is related to its gasification temperature, and the melting point is the boundary of its solid-to-liquid conversion.
    In terms of its chemical properties, due to the presence of bromine, methoxy and other groups, its activity is unique. Bromine atoms can cause nucleophilic substitution reactions, and methoxy groups also affect the distribution of their electron clouds, thereby affecting their chemical activity. In the field of organic synthesis, this compound may be an important intermediate. Due to its physical and chemical properties, it can participate in a variety of reactions to obtain other types of organic products. It may have outstanding application prospects in the pharmaceutical, materials and other industries.
    Technical Specifications & Labeling
    4 - Bromo - 2 - Methy - 1 - (Difluoromethoxy) Benzene is an important chemical compound. Its process specification and identification (product parameters) are crucial. When preparing this compound, the proportion of each reactant needs to be precisely controlled to ensure stable reaction conditions. The purity of the raw material should reach a very high standard to prevent impurities from interfering with the reaction process.
    Control of reaction temperature and time is also critical. The appropriate temperature and time can make the reaction fully proceed and improve the yield and purity of the product. And the reaction process needs to be carried out in a specific environment, such as under the protection of inert gas, to avoid side reactions such as oxidation.
    In terms of identification, product parameters must be detailed and accurate. Including chemical structure, purity data, physical properties, etc. This allows users to understand product characteristics, ensure safe and efficient use, and follow strict process specifications and accurate labeling in the field of chemical research and industrial production. It is the cornerstone of ensuring the quality of 4-Bromo-2-Methy-1 - (Difluoromethoxy) Benzene.
    Preparation Method
    The raw materials of 4 - Bromo - 2 - Methy - 1 - (Difluoromethoxy) Benzene are crucial to the production process, reaction steps, and catalytic mechanism.
    The raw materials are selected, which are based on compounds containing bromine, methyl and benzene rings, supplemented by reagents containing difluoromethoxy groups. Both require high purity to ensure accurate reaction.
    In the production process, the raw materials are first mixed in a reaction kettle in a specific ratio, and the temperature is controlled in a moderate range to ensure stable reaction. The reaction steps are orderly, and the raw materials are slowly heated at the beginning to activate, followed by a catalytic mechanism to intervene to urge the rearrangement and combination of chemical bonds. Exclusive catalysts can be selected to increase the reaction rate and yield. In the catalytic mechanism, the catalyst interacts with the raw material to reduce the reaction energy barrier and cause the reaction to be efficient. Through multi-step reaction and fine purification, high purity 4-Bromo-2-Methy-1 - (Difluoromethoxy) Benzene can be obtained to meet various needs.
    Chemical Reactions & Modifications
    There is a chemical substance today, named 4 - Bromo - 2 - Methy - 1 - (Difluoromethoxy) Benzene. In the field of chemistry, reaction and modification are the key. The reaction of this substance is the weight of chemical research. Its reaction may involve a variety of paths, and in order to achieve the best state, all ends must be carefully examined.
    As far as modification is concerned, it is intended to make this substance have different properties. Or change its stability, or increase its activity to meet different needs. However, modification is not easy, and it is necessary to know the structure of its molecules and clarify its chemical properties.
    In order to find the beauty of the reaction and modification of this substance, we should use scientific methods to investigate it carefully. Either adjust the conditions of the reaction, or choose a specific reagent to obtain the ideal result. In this way, it can be beneficial to the research of chemistry, paving the way for the use of this substance in various fields.
    Synonyms & Product Names
    4-Bromo-2-methyl-1 - (difluoromethoxy) benzene, this substance is used in the field of chemistry and has a wide range of uses. Its synonymous names also have various names. The names of chemical substances often vary due to regions, habits, and research focuses.
    In the industry, or they are called by aliases, which are all for the convenience of communication and description. The names of commercial products are also set up with the business operation and marketing activities of merchants. Although the names are different, the things referred to are all 4-bromo-2-methyl-1 - (difluoromethoxy) benzene.
    Its synonymous names, although each has its own expression, are all accurate references to this thing. The name of the product set by the merchant also hopes to recognize its characteristics and attract the attention of customers, so that the transaction can flow smoothly. In chemical research and commercial circulation, the names are diverse, referring to the same thing, just like the stars shining together for a month, each showing its own color, and gathering together in the logo of the thing.
    Safety & Operational Standards
    4 - Bromo - 2 - Methyl - 1 - (Difluoromethoxy) Benzene Safety and Operation Specifications
    Fu 4 - Bromo - 2 - Methyl - 1 - (Difluoromethoxy) Benzene is also a research object. To understand its safe operation, please check the following.
    #1. The key to survival
    This object should be placed in a place where it is dry and clear. Avoid direct sunlight to prevent its properties. The device must be kept secret, and do not let air and water vapor contact each other, or it may be biochemically damaged as a result. In addition, the earth is a source of fire, a source of fire, and fire prevention.
    #Second, the operation of the
    operation of the
    operation, the appropriate anti-damage. Such as anti-eye protection, the eyes can be protected from its harm; chemical-resistant gloves, to prevent skin damage; anti-gas masks, can prevent it from entering the lungs. The operation should be in the pass, so that the escape of the
    The note, it is appropriate, do not let the overflow. If there is a leak, immediately clean up with the appropriate adsorption, do not let it disperse. Mixing, in order, and mixing, pay attention to its reaction, if there is any problem, stop the operation immediately.
    #3. Urgent strategy
    If the skin is in trouble, quickly wash it with a lot of water and soap. If it enters the eye, urgently wash it with water and ask for treatment. If you eat it, do not urge vomiting, just do it as soon as possible, and make this thing clear, so as to help the person know its nature. Such as fire, according to its chemical properties, it is appropriate to make a fire, such as dry powder and carbon dioxide.
    Therefore, the research of 4 - Bromo - 2 - Methyl - 1 - (Difluoromethoxy) Benzene must be kept safe and operate to keep you safe and safe.
    Application Area
    4 - Bromo - 2 - Methy - 1 - (Difluoromethoxy) Benzene has a wide range of application fields. In the field of pharmaceutical research and development, this compound can be the basis for the creation of new agents. Its unique structure can interact with specific targets in organisms, or assist in the development of anti-disease drugs, and treat diseases for patients.
    In the field of materials science, it also has its uses. Or it can use its characteristics to improve the properties of materials, such as enhancing the stability and weather resistance of materials. The material can be maintained in good condition in different environments, so that it can be used in many industries such as construction and electronics.
    And in the field of organic synthesis, this compound is often used as a key intermediate. Chemists can use it to derive a variety of organic molecules, expand the boundaries of organic chemistry, and provide a new material basis for the development of many fields. Therefore, 4 - Bromo - 2 - Methy - 1 - (Difluoromethoxy) Benzene is of great value in various application fields.
    Research & Development
    Today there is a product called 4 - Bromo - 2 - Methy - 1 - (Difluoromethoxy) Benzene. As a chemical researcher, I have been focusing on the research and development of this substance for a long time.
    This product has unique properties and has great potential in the field of organic synthesis. After repeated experiments, its reactivity and selectivity can be studied. We use a variety of advanced methods to analyze the relationship between its structure and properties.
    In the study, we are committed to optimizing its preparation process, striving to increase yield and reduce costs. We also consider its impact on the environment and explore green and sustainable ways.
    Over time, if we can break through the current predicament, we will definitely be able to make it widely used in many fields such as medicine and materials, contributing to the development of the industry and promoting related industries to new frontiers. This is our unremitting pursuit.
    Toxicity Research
    In this world, there is a substance named 4 - Bromo - 2 - Methy - 1 - (Difluoromethoxy) Benzene, and it is important to study its toxicity.
    To observe this substance, the chemical structure is unique, or it contains potential harm. Toxicity research should investigate the reaction of organisms and observe its impact on cells and tissues.
    Try to take various organisms as samples and observe their symptoms after exposure to this substance. Or there are changes in physiological functions and different behaviors. Explore the way it enters the body, or through breathing, skin, or diet.
    It is clear that the strength of its toxicity is related to dose and time, which cannot be ignored. Only by knowing the location of its harm can it be used as a protective policy to protect people from safety, avoid the harm of poisons, and protect the well-being of the people.
    Future Prospects
    Today there is a product, named 4 - Bromo - 2 - Methy - 1 - (Difluoromethoxy) Benzene. I have studied this product for a long time, observed its properties, explored its preparation method, and achieved everything.
    Looking at the future prospects of the husband, this product has a good prospect. In the field of medicine, it may become a key ingredient of new agents, cure various diseases, and save people's pain. In the field of materials, it is also expected to be the foundation of new materials, give specific properties to materials, and expand the field of application.
    We should study it diligently, use its mysteries, and hope to develop its potential with the power of science and technology. With time, it will be able to make this material shine, for the well-being of the world, and add a splendid touch to the future scientific and technological journey, living up to the original intention of our generation's scientific research and exhibiting unprecedented brilliance.
    Where to Buy 4-Bromo-2-Methy-1-(Difluoromethoxy)Benzene in China?
    As a trusted 4-Bromo-2-Methy-1-(Difluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-2-Methy-1-(Difluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 4-Bromo-2-Methy-1- (Difluoromethoxy) Benzene?
    4-Bromo-2-methyl-1- (difluoromethoxy) benzene, which has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to its structure containing bromine atoms and difluoromethoxy groups, the two have unique reactivity. Bromine atoms can undergo many reactions, such as nucleophilic substitution, interact with various nucleophiles, introduce different functional groups, and then build complex organic molecular structures.
    In the field of medicinal chemistry, such compounds may have potential biological activity. With the special electronic and spatial effects of difluoromethoxy groups, it may affect the interaction between drugs and targets, laying the foundation for the development of new drugs. Scientists can explore lead compounds with higher activity and better selectivity based on the structure of this compound through modification and modification.
    In the field of materials science, it can also be used. Through appropriate chemical reactions, it can be introduced into the structure of polymer materials, giving the material unique properties. The existence of difluoromethoxy groups may improve the solubility, thermal stability and optical properties of materials, etc., which is of great value in the preparation of special functional materials.
    In industrial production, as an intermediate, it can be converted into high value-added products through a series of reactions. After optimizing the synthesis route and reaction conditions, large-scale production can be realized to meet the needs of different industries for this compound and derived products. In summary, 4-bromo-2-methyl-1- (difluoromethoxy) benzene has important uses in various fields such as organic synthesis, medicine, materials, and industrial production, promoting the development and innovation of related fields.
    What are the physical properties of 4-Bromo-2-Methy-1- (Difluoromethoxy) Benzene?
    4-Bromo-2-methyl-1- (difluoromethoxy) benzene is one of the organic compounds. Its physical properties are very important, and it is related to its performance in various chemical processes and practical applications.
    First of all, its appearance is usually a colorless to light yellow liquid, which is clear in appearance and has a special visual representation. The formation of this color state is due to the absorption and scattering characteristics of light by the internal structure of the molecule. In its molecular structure, the synergistic action of bromine atoms, methyl and difluoromethoxy gives it a unique electron cloud distribution, which in turn affects its optical properties.
    times and boiling points, about a certain temperature range. The existence of this temperature value is closely related to the intermolecular forces. There are van der Waals forces between molecules, including dispersion forces, induction forces and orientation forces, and due to the electronegativity differences of bromine atoms and fluorine atoms, a certain dipole-dipole interaction is formed. The combined action of various forces causes the compound to obtain enough energy to overcome the attractive forces between molecules at a specific temperature, and transform from a liquid state to a gaseous state, that is, to a boiling point.
    In addition, the melting point is also a key physical property. Its melting point is affected by the regularity of molecular arrangement. The shape and substituent distribution of the compound molecules determine the intermolecular stacking mode in the solid state. If the molecular arrangement is more regular, the intermolecular force can be effectively exerted, and the melting point is relatively high; conversely, when the arrangement is disordered, the melting point is lower.
    In addition, the solubility cannot be ignored. In organic solvents such as ethanol and ether, the compound exhibits good solubility. This is because the molecules of the organic solvent can form similar interactions with the compound molecules, such as van der Waals force or hydrogen bond (if conditions permit), following the principle of "similar miscibility". In water, the solubility is poor because of the large difference in molecular polarity from water molecules and the lack of groups that form strong interactions with water molecules.
    In terms of density, the compound has a specific value, which may be different from that of water. This density characteristic is derived from the relative mass of molecules and the degree of intermolecular compactness. The relative mass of bromine, fluorine and other atoms in the molecule is relatively large, and the compactness of the molecular structure also affects the density.
    In summary, the physical properties of 4-bromo-2-methyl-1 - (difluoromethoxy) benzene, such as appearance, boiling point, melting point, solubility and density, are determined by its unique molecular structure, and play an important role in many fields such as chemical research and industrial production, providing theoretical basis and practical basis for its application.
    What are the synthesis methods of 4-Bromo-2-Methy-1- (Difluoromethoxy) Benzene?
    The synthesis of 4-bromo-2-methyl-1- (difluoromethoxy) benzene has attracted much attention in the field of organic synthesis. Its synthesis path can be followed by several strategies.
    First, 4-bromo-2-methylphenol can be used as the starting material. This phenolic compound, after appropriate alkali treatment, such as potassium carbonate and other alkalis, converts its phenolic hydroxyl group into phenoxy anion, enhancing its nucleophilicity. Subsequently, the nucleophilic substitution reaction occurs with difluoromethyl halide, such as difluoromethyl bromide and other electrophilic reagents, and the difluoromethoxy group can be introduced to obtain the target product 4-bromo-2-methyl-1 - (difluoromethoxy) benzene. The key to this path lies in the selection of the base and the regulation of the reaction conditions. The strength of the base needs to be appropriate. Too strong or too weak may affect the reaction efficiency and selectivity. The reaction temperature and time also need to be carefully controlled. Usually, in an appropriate organic solvent, such as N, N-dimethylformamide (DMF), the reaction is stirred within a certain temperature range for several hours to tens of hours.
    Second, 2-methyl-1- (difluoromethoxy) benzene can also be used as a substrate to introduce bromine atoms through halogenation. The commonly used halogenation reagent is N-bromosuccinimide (NBS), which is heated and refluxed in an appropriate solvent such as carbon tetrachloride in the presence of an initiator such as benzoyl peroxide. In this process, factors such as the amount of initiator, the reaction temperature, and the dripping rate of the halogenated reagent have a significant impact on the regional selectivity and yield of the reaction. It is necessary to carefully investigate various factors before the bromine atom can be selectively substituted in the target position to obtain high-purity 4-bromo-2-methyl-1- (difluoromethoxy) benzene.
    Furthermore, the target molecule can also be constructed by the coupling reaction of bromine-containing and difluoromethoxy groups through the coupling reaction catalyzed by transition metals. For example, the palladium-catalyzed Suzuki coupling reaction uses bromine-containing aromatic hydrocarbon derivatives and difluoromethoxy-containing borate esters or boric acid derivatives as raw materials, and the reaction is carried out in a suitable solvent under the action of alkali and palladium catalysts. This method requires more stringent reaction conditions, and the activity of the catalyst, the selection of ligands, and the type of bases will significantly affect the process and results of the reaction. Careful screening of reaction parameters is required to achieve efficient and highly selective synthesis.
    What is the price range of 4-Bromo-2-Methy-1- (Difluoromethoxy) Benzene in the market?
    4-Bromo-2-methyl-1- (difluoromethoxy) benzene, this product is in the market price range, it is difficult to say exactly. Due to the fickle market conditions, the price of high or low often depends on a variety of factors.
    First, the state of supply and demand has a huge impact on its price. If there are many people, but the supply is small, the price may rise; conversely, if the supply exceeds the demand, the price will decline. For example, in a certain field recently, due to the large increase in demand for it in a specific industry, the supply will exceed the demand for a while, and its price will skyrocket.
    Second, the difficulty of preparation is also related to the price. If complex steps, rare raw materials, or harsh reaction conditions are required to synthesize the quality of this product, the cost will be high, and the price will also rise.
    Third, the market competition situation also affects its price. If there are many players competing with each other, in order to occupy the market seat, there may be a price reduction; if only a few companies control it, the price may be stable and high.
    Fourth, regional differences are also the key. In different places, due to differences in transportation costs, taxes, and local market characteristics, prices may vary widely. For example, in remote places, due to inconvenient transportation, the price may be significantly different from that in places with convenient transportation.
    Roughly speaking, the price of this substance varies from a few yuan to tens of yuan per gram, but this is only an approximate number. The actual price should be subject to real-time market conditions. To know the exact price, you need to consult the relevant chemical raw material supplier in detail, or refer to the latest quotation of the chemical product trading platform to get an accurate figure.
    What are the storage conditions for 4-Bromo-2-Methy-1- (Difluoromethoxy) Benzene?
    4-Bromo-2-methyl-1- (difluoromethoxy) benzene is also an organic compound. Its storage conditions are quite important, related to the stability and quality of this substance.
    In a room temperature environment, it needs to be placed in a dry place. Because moisture can easily lead to adverse reactions such as hydrolysis, damage its chemical structure and reduce its purity. Therefore, in the warehouse, it should be supplemented with a desiccant to make the environment dry and less wet.
    and should be stored away from light. Under light, this compound may have photochemical reactions, causing it to deteriorate. Therefore, the storage container should be dark, such as a brown glass bottle, which can block light from penetrating and protect it from light disturbance.
    Furthermore, the storage place should be well ventilated. In order to prevent the accumulation of volatile gas from the compound, one should avoid the danger of safety caused by its high concentration, and the other should avoid environmental odor.
    Temperature is also critical. Although it can be stored at room temperature, if the temperature fluctuates violently, it will also affect its properties. Therefore, the temperature should be controlled in a relatively stable range to avoid hot and cold.
    In addition, this compound should be stored separately from oxidants, acids, bases, etc. Due to its chemical properties, it may react violently in case of such substances, endangering safety.
    When storing, it is necessary to affix a label with the name, specification, date, etc. in detail. In order to access and trace, and to prevent misuse of mixed storage. In this way, the stability and safety of 4-bromo-2-methyl-1- (difluoromethoxy) benzene during storage can be guaranteed.