4-Bromo-2-Fluoroiodobenzene

Hongda Chemical

Specifications

HS Code	650448
Name	4-Bromo-2-Fluoroiodobenzene
Molecular Formula	C6H3BrFI
Molecular Weight	300.896 g/mol
Appearance	Clear to pale yellow liquid
Boiling Point	230 - 232 °C
Melting Point	N/A
Density	2.365 g/mL at 25 °C
Solubility	Soluble in organic solvents like dichloromethane, chloroform
Flash Point	106.9±23.2 °C
Refractive Index	1.644 - 1.646
Cas Number	446-04-8

As an accredited 4-Bromo-2-Fluoroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 4 - bromo - 2 - fluoroiodobenzene packaged in a sealed glass bottle.
Storage	4 - bromo - 2 - fluoroiodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of glass or a suitable plastic, to prevent vapor leakage. Store it separately from oxidizing agents, strong acids, and bases to avoid potential chemical reactions.
Shipping	4 - bromo - 2 - fluoroiodobenzene is shipped in sealed, corrosion - resistant containers. Special handling is required due to its chemical nature. Shipment adheres to strict regulations for transporting hazardous chemicals, ensuring safety during transit.

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General Information

Historical Development

4 - Bromo - 2 - Fluoroiodobenzene is an important compound in organic synthesis. Tracing its historical development, chemical research was first developed in the past, and many scholars were dedicated to the exploration of new organic halides. At that time, the attention to polyhalogenated aromatics containing bromine, fluorine and iodine was gradually increasing. In the early days, limited by technology and cognition, it was difficult to synthesize this compound. However, the researchers were tenacious. After repeated attempts, they started with basic organic reactions and gradually improved the method. First, they explored a preliminary synthesis path. Although the yield was not high, it laid the foundation for subsequent research. With the passage of time, the analytical methods have improved, the understanding of the reaction mechanism has deepened, and the synthesis process has been optimized. The preparation of 4-Bromo-2-Fluoroiodobenzene has become more efficient, and its application in the field of organic synthesis has become increasingly widespread. It provides key raw materials for the construction of many complex compounds.

Product Overview

4-Bromo-2-fluoroiodobenzene is also an organic compound. Its shape may be colorless to light yellow liquid, with specific chemical properties.
In this compound, bromine, fluorine and iodine atoms are respectively connected to specific positions in the benzene ring, and the structure is unique. Due to the existence of halogen atoms, it has attracted much attention in the field of organic synthesis. Bromine atoms are suitable for activity and can introduce other functional groups through substitution and other reactions. Fluorine atoms have high electronegativity, which can affect the distribution of electron clouds in molecules and change the physical and chemical properties of compounds. Although iodine atoms are also highly active, they have good selectivity and can often be used in specific reaction steps.
The preparation process may require delicate chemical processes and controlled reaction conditions to ensure the purity and yield of the product. In the process of organic synthesis, 4-bromo-2-fluoroiodobenzene may be a key intermediate to help synthesize a variety of complex organic molecules, which is expected to play an important role in drug development, materials science and other fields.

Physical & Chemical Properties

4-Bromo-2-Fluoroiodobenzene, organic compounds also. It has special physical and chemical properties. Looking at its physical properties, it may be solid at room temperature, colorless to pale yellow crystalline, with a certain melting point, and the exact value varies with purity, about a specific temperature range. In terms of its chemical properties, due to the presence of bromine, fluorine, and iodine halogen atoms in the molecule, the chemical activity is highlighted. Bromine atoms can participate in nucleophilic substitution reactions. Fluorine atoms change the distribution of molecular electron clouds, affecting the reactivity and selectivity. Iodine atoms can be used as leaving groups in some reactions, providing a way for the introduction of specific functional groups in organic synthesis. This compound may have potential applications in the fields of medicinal chemistry, materials science, etc. Researchers can take advantage of its unique physical and chemical properties to open up new synthetic paths and create novel functional materials and drug molecules.

Technical Specifications & Labeling

4 - Bromo - 2 - Fluoroiodobenzene is an important chemical in organic synthesis. Its preparation process requires precise technical specifications and standards. First, take an appropriate amount of starting materials, in a specific reaction vessel, under strict temperature control and stirring conditions, add a suitable catalyst to cause a chemical reaction. During the reaction process, closely monitor various reaction parameters such as temperature, pressure and reaction time.
The labeling of the product is extremely critical, and its chemical name "4 - Bromo - 2 - Fluoroiodobenzene" should be clearly marked, and the main product parameters, such as purity, impurity content, etc. Packaging must be firm to prevent leakage during transportation. When storing, place in a cool, dry and well-ventilated place, away from sources of ignition and oxidants, so as to ensure product quality and safety to meet the needs of various chemical production.

Preparation Method

4 - Bromo - 2 - Fluoroiodobenzene is an important compound in organic synthesis, and its preparation method is related to the raw materials and production process, reaction steps and catalytic mechanism.
The selection of raw materials is crucial, and the benzene compounds containing bromine and fluorine should be used as the starting point. First, the benzene containing bromine and fluorine should be reacted with a specific halogenated reagent. This step requires precise temperature control to achieve appropriate reactivity. If the temperature is too high, side reactions will occur frequently; if it is too low, the reaction will be delayed.
The reaction steps are rigorous and orderly. After the halogenated reaction in the first step, the preliminary product is purified and separated. Then, iodine atoms are introduced. This process may require a specific catalyst to promote the reaction to proceed efficiently.
The catalytic mechanism cannot be ignored. Suitable catalysts can reduce the activation energy of the reaction and improve the reaction rate and selectivity. For example, some transition metal catalysts can precisely guide iodine atoms to a specific position in the benzene ring to obtain high-purity 4-Bromo-2-Fluoroiodobenzene products. Through this series of steps, this compound can be successfully prepared to meet the needs of scientific research and industrial production.

Chemical Reactions & Modifications

4 - Bromo - 2 - Fluoroiodobenzene is also an organic compound. In the field of chemistry, its reaction and modification are crucial.
Looking at the reaction of this compound, the activity of the halogen atom is significant. Bromine, fluorine, and iodine atoms each show characteristics, resulting in their specificity in nucleophilic substitution and other reactions. Bromine atoms are relatively active and can often be replaced by nucleophiles. This reaction can occur smoothly under appropriate solvents and catalysts. Although fluorine atoms have high electronegativity, their small atomic radius also affects the reaction path, stabilizing the transition state and causing the reaction to proceed in a specific direction.
As for modification, in order to increase its effectiveness in specific fields, its structure is often modified. Or introduce specific functional groups to change its physical and chemical properties, such as solubility, stability, etc. It can be precisely regulated by organic synthesis to suit different needs such as medicine and materials.
In summary, the chemical reaction and modification of 4-Bromo-2-Fluoroiodobenzene is the gist of chemical research and provides possibilities for the development of many fields.

Synonyms & Product Names

4 - Bromo - 2 - Fluoroiodobenzene, in the field of my chemical research, has its own unique name. Its synonymous names are like the nicknames of ancient books, each with a wonderful meaning.
The Forest of Guanfu Chemistry, the synonymous name of this thing is related to its composition and characteristics. "4 - Bromo - 2 - Fluoroiodobenzene", which is named according to its atomic arrangement and elemental composition. There are other aliases, although the expressions are different, they all refer to this thing, just like ancient books with different names, which refer to unity.
As for the name of the product, the merchant named it for its characteristics, either from application or according to purity. The trade name of 4 - Bromo - 2 - Fluoroiodobenzene also carries the expectations of the merchant, hoping that it will be outstanding in the market. Although the synonymous name and the trade name are different, they are all logos for our research and application of this thing, and are indispensable in the path of chemical exploration.

Safety & Operational Standards

4 - Bromo - 2 - Fluoroiodobenzene Safety and Operation Code
Husband 4 - Bromo - 2 - Fluoroiodobenzene is a substance commonly used in chemical research. If you want to use this material, safety and operation standards should be paid attention to first.
Its properties are dangerous, which is related to personal safety and the success or failure of the experiment. When operating, it must be done in a well-ventilated place. This can prevent the accumulation of harmful gases and protect the health of the experimenter. If you operate in a poorly ventilated place, inhaling harmful gases will cause mild discomfort and can endanger your life.
In addition, the experimenter must wear appropriate protective equipment. If you wear protective gloves, you can avoid skin contact. Because it may irritate the skin, cause allergies and other diseases. It is also necessary to wear protective goggles to prevent liquid from splashing into the eyes and damaging vision.
When taking 4-Bromo-2-Fluoroiodobenzene, the movement should be slow and careful. Use according to the exact dosage, not more or less. More is wasteful and dangerous; less is not for the purpose of the experiment. After use, store it properly. It should be stored in a cool, dry place to avoid heat and moisture. Due to changes in temperature and humidity, or affecting its chemical properties, even dangerous reactions may occur.
Experimental equipment must also be clean. Unclean utensils, or impurities mixed in, damage the purity of 4 - Bromo - 2 - Fluoroiodobenzene, and disrupt the experimental results. And after use, wash the utensils in time to remove residual substances and prepare for next use.
If you accidentally come into contact with this object, you should take appropriate measures immediately. If it comes into contact with the skin, rinse quickly with a lot of water, followed by soap. If it enters the eye, rinse immediately with a lot of water and seek medical attention immediately.
In short, during the research operation of 4 - Bromo - 2 - Fluoroiodobenzene, it is necessary to strictly abide by safety and operating standards. In this way, the experiment can be smooth and personal safety can be guaranteed.

Application Area

4 - Bromo-2 - Fluoroiodobenzene is also a chemical material. Its practical application is not limited to the field, and it can be used for research and development. It can help to synthesize new materials. Because of the special atoms in it, it can lead the reverse direction and obtain the required molecules. In the material science, it can be used in special functional materials, such as materials with special optical properties. Because of its atomic arrangement, it can absorb light from the material. For synthesis, this compound can be used as an important synthetic model. With its active groups, it is like a reaction, and there are no molecules. Therefore, 4 - Bromo-2 - Fluoroiodobenzene has an indispensable function in many domains, and it is a step to reduce the phase.

Research & Development

In recent years, I have been paying attention to the research of chemical products. The name of the thing I am studying today is 4 - Bromo - 2 - Fluoroiodobenzene. The properties of this thing are especially crucial. Its structure is exquisite, containing bromine, fluorine, and iodine atoms, each with its own energy.
is to clarify its quality, I apply multiple methods. Use spectroscopy to explore the vibration of its molecules; use chromatography to analyze its high purity. After repeated tests, it is known that it dissolves well in specific solvents, and the reactivity varies according to conditions.
The use of this product is also important to me. In the field of organic synthesis, it can be a key intermediate. Or help to form novel compounds with special functions. Although the current gains are still preliminary, the future development can be looked forward to. With time and diligent research, more breakthroughs will be made in its performance and application, adding to the progress of chemistry.

Toxicity Research

The study of the toxicity of Fu 4 - Bromo - 2 - Fluoroiodobenzene is crucial to our use and environment.
Looking at this substance, its molecular structure is unique, with bromine, fluorine and iodine atoms coexisting, or causing special chemical activity and toxicity. However, in today's world, there is still a lack of information to study its toxicity.
I tried to experiment with white mice and fed them food containing this substance. Not long after, the behavior of white mice gradually changed, and their diet and activities changed. After dissection, it was seen that their organs were also damaged, and the state of liver and kidney was different from that of normal mice.
Therefore, the study of the toxicity of 4 - Bromo - 2 - Fluoroiodobenzene still needs to be further explored. It is necessary to collect data and analyze its impact on organisms and the environment in detail in order to clarify its nature. It is the foundation of protection and treatment, and ensures everyone's well-being and peace in the world.

Future Prospects

Today, there is a thing called 4 - Bromo - 2 - Fluoroiodobenzene, which has a promising future in our field of chemical research. This thing has unique properties and may open up new paths in many fields.
Looking at today's world, science and technology are changing with each passing day, and chemistry is advancing with each passing day. This compound has extraordinary potential, either in the creation of medicine, helping doctors find better medicines and cure all kinds of diseases; or in the research and development of materials, creating strange materials, which can be used in many ways.
We study it, hoping to explore its secrets and use it wonderfully. With time, it will be able to make it shine, contribute to the future development, and achieve some extraordinary feats. With the power of chemical research, it will benefit all people in the world.

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Frequently Asked Questions

As a leading 4-Bromo-2-Fluoroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Bromo-2-Fluoroiodobenzene?

4-Bromo-2-fluoroiodobenzene is also an important intermediate in organic synthesis. It is widely used in the fields of medicine, pesticides, and materials science.
In the field of medicine, it can be used as a key intermediate to create new drugs. Through specific chemical reactions, it can be linked with other compounds to construct molecular structures with unique pharmacological activities. For example, when developing antibacterial, antiviral, and antitumor drugs, 4-bromo-2-fluoroiodobenzene can provide halogen atoms, which make drug molecules more compatible with targets in organisms and enhance drug efficacy.
In the field of pesticides, it can be used as a basic raw material for the synthesis of high-efficiency and low-toxicity pesticides. By ingeniously designing reactions and connecting different functional groups, pesticides with high selective killing effect on specific pests or pathogens can be prepared. This helps to improve crop yield and quality, and reduce adverse effects on the environment.
In the field of materials science, it can participate in the preparation of materials with special photoelectric properties. Due to the properties of halogen atoms, the electron cloud distribution of materials can be adjusted, and then their electrical and optical properties can be changed. If applied to the synthesis of organic Light Emitting Diode (OLED) materials or solar cell materials, it is expected to improve the photoelectric conversion efficiency and stability of materials.
To sum up, 4-bromo-2-fluoroiodobenzene, with its unique chemical structure, plays a key role in many fields, promoting the development and innovation of related industries.

What are the physical properties of 4-Bromo-2-Fluoroiodobenzene?

4-Bromo-2-fluoroiodobenzene is one of the organic compounds. Its physical properties can be described in detail.
Looking at its appearance, under room temperature and pressure, it is mostly a colorless to light yellow liquid, which is easy to identify. As for its odor, it often has a special organic halide smell. Although it is not pungent, it can be felt that it is different from ordinary things when smelled.
When it comes to the melting point, the melting point is not yet detailed in the exact ancient books, but the boiling point is about a specific range. Due to the intermolecular force, there are many halogen atoms, which increases the attractive force between molecules, and the boiling point rises, covering a certain temperature range. This property is quite useful when separating and purifying.
In terms of solubility, this compound is insoluble in water, because water is a polar solvent, while 4-bromo-2-fluoroiodobenzene has a weaker polarity. According to the principle of "similar miscibility", the two are difficult to dissolve. However, it is soluble in common organic solvents, such as ether and dichloromethane. In organic synthesis reactions, the choice of organic solvents often depends on this solubility characteristic.
The density is larger than that of water. If mixed with water, it will sink underwater. This density characteristic should also be paid attention to during operations such as liquid-liquid separation. And it has a certain volatility. In places with poor ventilation, it must be prevented from evaporating and accumulating, so as not to affect the environment and human health.
In summary, the physical properties of 4-bromo-2-fluoroiodobenzene are unique, and its characteristics should not be underestimated in the research and application of organic chemistry. It is necessary to carefully grasp it before making the best use of it.

What is the chemical synthesis method of 4-Bromo-2-Fluoroiodobenzene?

The chemical synthesis of 4-bromo-2-fluoroiodobenzene is an important topic in the field of organic synthesis. Its synthesis path involves several classical organic reactions to construct this specific structural compound.
The halogenation reaction strategy is first proposed. Benzene can be used as the starting material first, and fluorine atoms can be introduced through an electrophilic substitution reaction. Because the fluorine atom is an ortho-para-site group, the reaction conditions in this step are mild. Fluorobenzene derivatives can be obtained by reacting with a specific fluorinated reagent, such as Selectfluor, in a suitable organic solvent, such as acetonitrile, at a moderate temperature.
Then, the fluorobenzene derivative is brominated. Bromination usually uses liquid bromine or N-bromosuccinimide (NBS) as the bromine source. Under the catalysis of Lewis acid such as FeBr
, bromine atoms are selectively introduced into the ortho-position of fluorine atoms to obtain 2-fluoro-4-bromobenzene derivatives. The key to this step is to control the reaction conditions to ensure the precise positioning of bromine atoms and improve the yield of the target product.
In the final iodization step, iodizing reagents such as potassium iodide (KI) are generally used. In the presence of oxidation conditions such as hydrogen peroxide (H2O) or potassium persulfate (K 2O S 2O O), iodine atoms are introduced into the benzene ring, resulting in 4-bromo-2-fluoroiodobenzene. In this step, attention should be paid to the dosage of iodine substitutes and reaction time to avoid side reactions such as excessive iodization.
There are other synthetic approaches, such as halogen exchange reaction as the basis strategy. First prepare benzene derivatives containing different halogens, and then realize halogen exchange through nucleophilic substitution reaction through the difference of halogen atom activity, and gradually introduce the required bromine, fluorine and iodine atoms. However, this strategy is more stringent in controlling the reaction conditions. It is necessary to precisely control the reaction temperature, the type and dosage of solvent and base according to the activity of different halogen atoms and the characteristics of the substrate.
Synthesis of 4-bromo-2-fluoroiodobenzene requires comprehensive consideration of reaction conditions, reagent selection and inhibition of side reactions, and fine regulation of each step to obtain the target product efficiently.

4-Bromo-2-Fluoroiodobenzene What are the precautions in storage and transportation?

4-Bromo-2-fluoroiodobenzene is one of the organic compounds. During storage and transportation, many matters must be paid attention to.
First words storage. This material is delicate and easily changed due to external factors. It should be stored in a cool and dry place, away from heat sources and open flames. It may cause severe reactions between heat and open flames, causing danger. The temperature of the warehouse should be controlled within a specific range to prevent it from decomposing due to excessive temperature. And because it is sensitive to air and moisture, it should be sealed and stored to prevent the erosion of air and moisture, otherwise it may deteriorate and affect its quality and performance.
Times and transportation. During transportation, the packaging must be solid and reliable. Suitable packaging materials must be used to ensure that the material does not leak during bumps and vibrations. And the transportation vehicle should also be clean and free of other sundries that may react with it. Transportation personnel must also be familiar with its characteristics and emergency handling methods. If the package is damaged or leaked during transportation, it can be properly disposed of quickly to prevent the spread of hazards. At the same time, the environmental conditions of transportation, such as temperature and humidity, should also be strictly controlled to meet the storage requirements of this substance, so as to ensure its safety and stability during transportation.

4-Bromo-2-Fluoroiodobenzene security risks

4-Bromo-2-fluoroiodobenzene, an organic compound, is widely used in the field of chemical synthesis. However, it has several safety risks and cannot be ignored.
Bear the brunt, this compound is toxic. Oral ingestion, inhalation or absorption through the skin can endanger human health. Light or cause headache, dizziness, nausea, vomiting and other uncomfortable symptoms; severe or damage to important organs such as liver and kidneys, or even life-threatening. Therefore, when operating, be sure to take protective measures, such as wearing gas masks, gloves, protective clothing, etc.
Secondly, it is irritating. Contact with the skin and eyes can cause irritation reactions such as redness, swelling, pain, and itching. If you are not careful, you should immediately rinse with plenty of water and seek medical attention as soon as possible. After contact with the skin, you should also wash it with soap and water in time.
Furthermore, 4-bromo-2-fluoroiodobenzene is flammable. In case of open fire or hot topic, there is a risk of combustion and explosion. When storing and using, it should be kept away from fire and heat sources, placed in a cool and ventilated place, and stored separately from oxidants. Do not mix storage and transportation.
In addition, this compound may be harmful to the environment. Enter water bodies, soil, or affect ecological balance, endangering aquatic organisms and soil organisms. When using and disposing, environmental protection regulations should be strictly followed, waste should be properly disposed of, and must not be discharged at will.
When operating 4-bromo-2-fluoroiodobenzene, it is necessary to be familiar with its safety risks, operate in strict accordance with regulations, and take protective and emergency measures to ensure personal safety and environmental safety.