Hongda Chemical
Products
Home  /  Products  / 

4-Bromo-2-Fluorobenzenesulphonyl Chloride

4-Bromo-2-Fluorobenzenesulphonyl Chloride

Hongda Chemical

    Specifications

    HS Code

    496700

    Chemical Formula C6H3BrClFO2S
    Molecular Weight 289.51
    Appearance Typically a solid
    Color May be white to off - white
    Melting Point Specific value would require literature search
    Boiling Point Specific value would require literature search
    Density Data would need to be sourced from literature
    Solubility Solubility characteristics vary with solvents; may be soluble in some organic solvents
    Pungency Likely has a pungent odor due to the presence of sulfonyl chloride group
    Reactivity Reactive towards nucleophiles due to the electrophilic nature of the sulfonyl chloride group

    As an accredited 4-Bromo-2-Fluorobenzenesulphonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4 - bromo - 2 - fluorobenzenesulphonyl chloride in a sealed, corrosion - resistant bottle.
    Storage 4 - bromo - 2 - fluorobenzenesulphonyl chloride should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It must be kept in a tightly - sealed container, preferably made of corrosion - resistant material, as it is reactive. Store it separately from incompatible substances like oxidizing agents, bases, and moisture - sensitive materials to prevent chemical reactions.
    Shipping 4 - bromo - 2 - fluorobenzenesulphonyl chloride is a chemical. Ship it in well - sealed, corrosion - resistant containers. Follow strict hazardous material shipping regulations. Ensure proper labeling and documentation for safe transport.
    Free Quote

    Competitive 4-Bromo-2-Fluorobenzenesulphonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: info@alchemist-chem.com

    4-Bromo-2-Fluorobenzenesulphonyl Chloride 4-Bromo-2-Fluorobenzenesulphonyl Chloride
    General Information
    Historical Development
    4-Bromo-2-fluorobenzenesulfonyl chloride is also a genus of chemical products. It first appeared in the academic world and has been studied by several generations of scholars. At the beginning, the synthesis method was still simple, and the yield was not abundant, but the research heart of the academic world was still there. As the years passed, various sages worked hard on the synthesis technology, improving the method and improving the yield, so that the chemical was gradually used in the chemical industry, medicine and other fields. Its development was not achieved overnight. It was only through repeated experiments by scholars in the laboratory, and careful investigation of reaction conditions and raw material ratios, that this chemical could be perfected day by day, playing an increasingly important role in industrial practice, benefiting the world, and promoting the progress of related industries.
    Product Overview
    Today there is a substance called 4 - Bromo - 2 - Fluorobenzenesulphonyl Chloride. It is an organic compound with unique chemical properties. Looking at its structure, bromine atoms, fluorine atoms and benzenesulfonyl chloride groups are cleverly connected.
    This substance is quite useful in the field of organic synthesis. It can be used as a key intermediate and participates in many organic reactions. If it reacts with nucleophiles, it can introduce specific functional groups to build complex organic molecules.
    Its physical properties are also worthy of attention. At room temperature or in a specific color state, melting boiling point and other properties have a great impact on its storage and use. In chemical experiments and industrial production, it is necessary to operate properly according to its characteristics in order to maximize its effectiveness and promote the development of organic chemistry research and related industries.
    Physical & Chemical Properties
    4 - Bromo - 2 - Fluorobenzenesulphonyl Chloride is a chemical substance, and its physicochemical properties are crucial. This substance is solid, white in color and has a certain crystalline form. Looking at its physical properties, its melting point is specific, which has a great impact on its preservation and application. It can maintain stability in a specific temperature environment. Its density is also a key indicator, which is related to the distribution in different media.
    When it comes to chemical properties, bromine, fluorine and sulfonyl chloride groups in 4 - Bromo - 2 - Fluorobenzenesulphonyl Chloride are all active. Sulfonyl chloride groups are easy to react with nucleophiles and can be used in many organic synthesis to form sulfonates or sulfonamides. Bromine atoms can participate in the substitution reaction and expand the diversity of molecular structures. The introduction of fluorine atoms enhances molecular stability and unique electronic effects, making it a great potential for application in the fields of medicinal chemistry and materials science. However, due to its chemical activity, it is necessary to avoid water and alkali when storing to prevent deterioration.
    Technical Specifications & Labeling
    4-Bromo-2-fluorobenzenesulfonyl chloride is involved in the research of chemical products. Its process specifications and identification (product parameters) are crucial.
    The process specifications of this product need to follow a specific method. The selection of raw materials, when refined and pure, must be accurate. The temperature and time of the reaction are fixed and cannot be exceeded slightly. Through various reactions, the purity and properties of this product should be in line with the standard.
    As for the identification (product parameters), its name is established as 4-bromo-2-fluorobenzenesulfonyl chloride, and the molecular formula, molecular weight and other parameters must be clear. The appearance of the state, the signs of color and taste, also need to be recorded in detail. This is the basis for identifying products and standardizing their use, and is indispensable in the chemical industry.
    Preparation Method
    To prepare 4 - Bromo - 2 - Fluorobenzenesulphonyl Chloride, the method is as follows:
    Prepare raw materials, based on benzene compounds containing bromine and fluorine. In an appropriate reaction vessel, add such raw materials and proceed with a specific chemical reaction process. The first step is to adjust the reaction conditions, such as temperature, pressure and catalyst dosage, according to the reaction steps. Make the raw materials undergo a specific reaction and gradually transform.
    During the reaction process, each link is carefully controlled to ensure that the reaction proceeds in a predetermined direction. In this regard, the transformation mechanism is very critical. Through ingenious design, the molecular structure is gradually transformed to achieve the structure of the target product.
    After the reaction is completed, the product can be separated and purified after subsequent treatment to obtain 4-Bromo-2-Fluorobenzenesulphonyl Chloride. The whole preparation process, the selection of raw materials and the control of the reaction process are all key, which are related to the purity and yield of the product.
    Chemical Reactions & Modifications
    In the field of chemistry, the study of its reaction and modification is quite important.
    Looking at the reaction, the bromine, fluorine and sulfonyl chloride groups of this compound are all active. Bromine groups can participate in nucleophilic substitution, and can be translocated to form new chemical bonds when appropriate nucleophilic reagents are used. Although fluorine groups are small, their strong electronegativity can affect the electron cloud distribution of molecules, thereby changing the reactivity and selectivity of compounds. Sulfonyl chloride groups are often electrophilic reagents and can react with electron-rich substrates to derive a variety of products.
    As for modification, in order to optimize its properties, or through chemical modification, its molecular structure can be adjusted. For example, the introduction of specific functional groups to change its solubility, stability or biological activity. This is why chemists study this substance carefully and strive to explore its optimal reaction conditions and modification strategies in order to achieve the wonders of chemical applications.
    Synonyms & Product Names
    4 - Bromo - 2 - Fluorobenzenesulphonyl Chloride, a kind of chemical substance. Its trade name is the same, and it is also noted in the study.
    This compound has a unique property. In the field of chemistry, it may have a general name, which is derived from the same name due to different uses, research processes and business. Its trade name, or according to the family, in recognition of its characteristics, products, or specific market needs.
    Those who study it, are clearly identified with the same, and its use in the text, report, communication, or alternately. If it cannot be communicated, it may be confused, and the meaning may be understood, resulting in research bias. Therefore, intensive study of the same product name of this thing is a must-have ability for researchers to help them understand and explore accurately, and in the way of transformation, they can achieve success.
    Safety & Operational Standards
    4-Bromo-2-fluorobenzenesulfonyl chloride
    4-bromo-2-fluorobenzenesulfonyl chloride is also a commonly used material in chemical preparation. To clarify its safety and operation specifications, be sure to check the following matters in detail.
    In terms of safety, this compound is dangerous. It is corrosive. If it touches the skin, rinse with plenty of water as soon as possible, followed by appropriate chemicals, and should not be ignored. If it enters the eye, immediately open the eyelids, rinse with flowing water or normal saline, and seek medical attention immediately. Due to its irritation, during operation, it is necessary to prevent inhalation of its volatile aerosol. It is suitable for doing it in a well-ventilated place, or to prepare a gas mask.
    As for the operation specifications, the first thing is to use special equipment when using it, measure it accurately, and do not let it spill. When storing, it should be placed in a cool, dry and ventilated place, away from fire and heat sources to prevent deterioration or danger. In the operation room, all kinds of fire and emergency treatment equipment should be readily available for emergencies.
    Furthermore, the operator must wear protective clothing, including protective clothing, protective gloves and protective glasses, to ensure their own safety. During the reaction process, the temperature, time and proportion of the material should be strictly controlled according to the established procedures, and must not be changed without authorization. If there are waste materials, they should also be properly disposed of according to regulations and should not be discarded at will to avoid polluting the environment.
    All these are the essentials of the safety and operation of 4-bromo-2-fluorobenzenesulfonyl chloride. Practitioners should keep in mind to ensure smooth and safe operation.
    Application Area
    4 - Bromo - 2 - Fluorobenzenesulphonyl Chloride is also a chemical compound. Its use is important in the field of synthesis, and it can be used to generate biologically active compounds. For example, in some cases, it is necessary to use this material in a specific basis to give the desired activity properties of the compound.
    In the context of materials science, it is also useful. Or it can be modified to introduce specific functionalities to repair the surface properties of materials and improve their resistance and wear resistance. In the process of chemical research, it is an important starting point for exploring new anti-theory and expanding the synthesis path. It is a step for researchers to explore more possible synthesis strategies and promote the transformation of the field.
    Research & Development
    In recent years, I have been studying chemical substances, especially 4 - Bromo - 2 - Fluorobenzenesulphonyl Chloride. The characteristics of this substance are very different, and it has great potential in organic synthesis.
    At the beginning, analyze its structure, understand the beauty of its atomic relationship, and explore the rules of its chemical bonding. Then, try different methods to make it. Or choose various raw materials, adjust their proportions, control the temperature and time of the reaction, and hope to obtain high-purity products.
    During the process, I encountered various problems. The reaction rate was not as expected, and the removal of impurities was also a difficult matter. However, I was not discouraged, and repeatedly inferred, referred to ancient and modern literature, and interviewed peers.
    Finally, the method of optimization has gradually become, and the quality and quantity of the product have improved. And thinking about the future use of this thing, it can be used in the fields of medicine and materials, or it can open up an innovation bureau, contribute to the development of chemistry, and hope for my research. It can lead to common research and promote its wide application, so as to benefit the world.
    Toxicity Research
    The study of taste and smell of material properties is related to the importance of people's livelihood. Today there is a thing named 4 - Bromo - 2 - Fluorobenzenesulphonyl Chloride, and the study of its toxicity should not be ignored.
    The nature of this thing may be potentially dangerous. Between experiments, observe its contact with other things, and the changes that occur are related to the appearance of toxicity. If you accidentally contact it, you may hurt the skin, and if you enter the body, you may mess with the viscera.
    As a matter of fact, a rigorous method should be followed. Observe its state in different situations, measure the degree of its reaction, and clarify the depth and scope of toxicity. This research is not only to recognize the nature of this thing, but also to prevent it from harming Weimeng, to ensure the well-being of everyone, and to make the chemical industry stable and progressive, free from the disturbance of poison.
    Future Prospects
    Wuguanfu 4 - Bromo - 2 - Fluorobenzenesulphonyl Chloride, its chemical research in today, emerging, the future development, considerable. This compound has a unique structure, bromine, fluorine atoms, and benzenesulfonyl chloride groups, with different characteristics, a wide range of uses.
    In the field of organic synthesis, it can be a key intermediate. With its activity, it can introduce functional groups into organic molecules to produce a variety of compounds. Pharmaceutical research and development, or can be used as a lead compound, modified and transformed into a good drug for the treatment of diseases. Materials science, or can endow materials with new properties, such as improving heat resistance, chemical resistance, etc.
    Looking to the future, researchers should deeply explore its reaction mechanism, optimize the synthesis path, improve the yield and reduce the cost. Expand the application field, and hope to shine in emerging disciplines such as new energy and environmental science. In time, 4 - Bromo - 2 - Fluorobenzenesulphonyl Chloride will surely contribute to human well-being, make outstanding contributions, have bright prospects, and can be expected to achieve great success.
    Where to Buy 4-Bromo-2-Fluorobenzenesulphonyl Chloride in China?
    As a trusted 4-Bromo-2-Fluorobenzenesulphonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-2-Fluorobenzenesulphonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Bromo-2-Fluorobenzenesulphonyl Chloride?
    4-Bromo-2-fluorobenzenesulfonyl chloride, which is a crucial chemical reagent in the field of organic synthesis, has a wide range of uses.
    In the field of drug synthesis, it is often used as a key intermediate. Gein benzenesulfonyl chloride groups have active chemical properties and can be linked to other organic molecules through many reactions. For example, they can react with compounds containing amino groups to form sulfonamides. Many drug molecular structures contain sulfonamide fragments, which often have a key impact on the activity and selectivity of drugs. By introducing 4-bromo-2-fluorobenzenesulfonyl chloride, a specific drug skeleton can be constructed, laying the foundation for the development of drugs with novel structures and excellent pharmacological activities.
    In the field of materials science, it also shows unique value. It can be used to prepare functional polymer materials. By polymerizing with monomers containing unsaturated bonds, benzenesulfonyl chloride and special groups such as bromine and fluorine are introduced into the polymer chain. The introduction of fluorine atoms can enhance the chemical resistance and weather resistance of the material; bromine atoms can impart flame retardant properties to the material. In this way, the prepared polymer materials can be applied to fields such as aerospace, electronics and electrical appliances that require strict material properties.
    Furthermore, in the study of organic synthesis methodology, 4-bromo-2-fluorobenzenesulfonyl chloride is also a commonly used reactant. Chemists have expanded the strategies and methods of organic synthesis by exploring new reactions in which it participates. For example, exploring its reaction with different nucleophiles under transition metal catalysis, developing efficient and selective organic synthesis pathways, and promoting the development of organic chemistry.
    To sum up, 4-bromo-2-fluorobenzenesulfonyl chloride plays an indispensable role in many fields such as drug synthesis, materials science, and organic synthesis methodology, and is of great significance to promote the progress of related fields.
    What are the physical properties of 4-Bromo-2-Fluorobenzenesulphonyl Chloride?
    4-Bromo-2-fluorobenzenesulfonyl chloride, the properties of this substance are quite critical and related to many practical aspects. Its color state is often white to light yellow crystalline powder. This color and shape are the most important characteristics when identifying.
    When talking about the melting point, it is about 42-46 degrees Celsius. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. This value is stable and can be an important basis for identification and purification.
    The boiling point also has characteristics. Under specific pressure conditions, it can reach a certain value. However, the exact boiling point varies depending on the external pressure, and it usually boils at a higher temperature. The determination of the boiling point can help to separate and purify the substance.
    In terms of solubility, it has a certain solubility in most organic solvents, such as dichloromethane, chloroform, toluene, etc. This property enables it to be well dispersed in the reaction system in the organic synthesis reaction, and fully contact with other reagents to promote the reaction.
    4-Bromo-2-fluorobenzenesulfonyl chloride has active chemical properties, among which the sulfonyl chloride group (-SO 2O Cl) is highly reactive. It is easy to react with nucleophilic reagents, such as with alcohols, to form corresponding sulfonates; when reacted with amines, it can form sulfonamides. The bromine and fluorine atoms on the benzene ring can also participate in specific substitution reactions, giving the substance rich chemical reaction possibilities and wide application in the field of organic synthesis.
    Its stability needs to be paid attention to, in humid air, it is easy to hydrolyze to form corresponding sulfonic acid and hydrogen chloride gas. Therefore, when storing, it needs to be placed in a dry environment to isolate water vapor to avoid deterioration.
    This is the approximate physical properties of 4-bromo-2-fluorobenzenesulfonyl chloride. Applications in chemical, pharmaceutical and other fields depend on these properties.
    4-Bromo-2-Fluorobenzenesulphonyl Chloride chemically stable?
    4-Bromo-2-fluorobenzenesulfonyl chloride, this physical property is not fixed. It is active and easy to cause various reactions, so it is difficult to say stable.
    Looking at its structure, the two atoms of bromine and fluorine are connected to the benzene ring, and there are sulfonyl chloride groups attached to it. The activity of sulfonyl chloride is quite high, and it is easy to hydrolyze in contact with water, resulting in corresponding sulfonic acid and hydrogen chloride. Its hydrolysis is like Tang Woxue, which is fast and strong. When tested with water, you can see smoke rising. This is the appearance of hydrogen chloride escaping, which proves its hydrolysis drama.
    Because of its halogen atom and sulfonyl chloride group, it is also active in nucleophilic substitution reactions. Nucleophiles are easy to attack their positions and cause substitution. If it encounters alcohols, chlorine in the sulfonyl chloride group can be replaced by alkoxy groups to form sulfonates. This reaction is also prone to occur under suitable conditions, which shows the agility and variability of its chemical properties.
    When storing it, be careful. Keep it away from water and moisture, and place it in a dry, cool and ventilated place. If it is not stored properly, the risk of hydrolysis will increase greatly, not only losing its original physical properties, but also causing dangerous conditions, such as hydrogen chloride escaping to rot and poison.
    In summary, 4-bromo-2-fluorobenzenesulfonyl chloride is chemically active and has poor stability. It is necessary to use and store it according to its characteristics, so as to ensure safety and promote the reaction.
    What is the preparation method of 4-Bromo-2-Fluorobenzenesulphonyl Chloride?
    4-Bromo-2-fluorobenzenesulfonyl chloride is a commonly used reagent in organic synthesis. The method of its preparation has been recorded in the literature in the past, and the details are described later.
    First, 4-bromo-2-fluorobenzene is used as the starting material. This raw material can be co-heated with fuming sulfuric acid, chlorosulfonic acid and other sulfonating reagents. During the sulfonation process, the reaction temperature and time need to be carefully regulated. Usually, the temperature should be controlled in a specific range, such as between 80-100 ° C, for a duration of about several hours. In this way, a sulfonic acid group can be introduced on the benzene ring to obtain 4-bromo-2-fluorobenzenesulfonic acid.
    Then, the obtained 4-bromo-2-fluorobenzenesulfonic acid reacts with a chlorination reagent. Commonly used chlorination reagents include phosphorus pentachloride, thionyl chloride, etc. If phosphorus pentachloride is taken as an example, 4-bromo-2-fluorobenzenesulfonic acid is mixed with an appropriate amount of phosphorus pentachloride and reacted at an appropriate temperature, such as 60-80 ° C. During this reaction, the hydroxyl group of the sulfonic acid group can be replaced by a chlorine atom, so 4-bromo-2-fluorobenzenesulfonic chloride is obtained.
    The reaction is over, and the product often contains impurities, so purification is required. Methods such as reduced pressure distil If a suitable organic solvent is used to dissolve and recrystallize the product to remove impurities, a pure 4-bromo-2-fluorobenzenesulfonyl chloride can be obtained. This preparation method, according to the previous literature, has been practiced many times, and the target product can be effectively obtained.
    What are the precautions for 4-Bromo-2-Fluorobenzenesulphonyl Chloride in storage and transportation?
    4-Bromo-2-fluorobenzenesulfonyl chloride is a chemical substance. When storing and transporting, many matters must be paid attention to.
    First word storage. This substance should be placed in a cool, dry and well-ventilated place. Because of the cool environment, it can reduce the risk of reaction due to excessive temperature, and drying can avoid contact with water vapor to prevent adverse reactions such as hydrolysis. Good ventilation can disperse harmful gases that may leak in time and ensure the safety of the storage environment. And be sure to keep away from fire and heat sources. Because of its chemical activity, it is easy to cause danger in case of open flames and hot topics. At the same time, it should be stored separately from oxidizing agents, alkalis, etc., and must not be mixed. It is easy to chemically react with such substances and cause safety accidents.
    Times and transportation. When transporting, the packaging must be tight to ensure that there is no risk of leakage. The packaging materials used must be resistant to the corrosion of the substance to protect the integrity of the transportation process. The transportation process should be protected from exposure to the sun, rain, and high temperature. The transportation vehicle should also be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. The escort personnel must be familiar with the nature of the substance and the emergency treatment method, and regularly check the condition of the packaging during transportation. If there is any leakage and other abnormalities, they should be properly handled immediately according to the regulations. When loading and unloading, the operation must be handled lightly, and it is strictly forbidden to drop or press, so as to avoid packaging damage, material leakage, and endangering personnel and the environment.