4-Bromo-2-Fluorobenzenesulfonamide

Hongda Chemical

Specifications

HS Code	972600
Chemical Formula	C6H5BrFNO2S
Molecular Weight	254.07
Appearance	Solid (Typical)
Melting Point	165 - 169 °C
Solubility In Water	Low solubility
Solubility In Organic Solvents	Soluble in some organic solvents like dichloromethane
Purity	Typically high - purity (95%+ in commercial products)

As an accredited 4-Bromo-2-Fluorobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 4 - bromo - 2 - fluorobenzenesulfonamide in a sealed, labeled chemical - grade bottle.
Storage	4 - bromo - 2 - fluorobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and direct sunlight. Store in a tightly sealed container to prevent moisture and air exposure, which could potentially lead to degradation. Separate it from incompatible substances like strong oxidizing agents and bases.
Shipping	4 - bromo - 2 - fluorobenzenesulfonamide is shipped in well - sealed containers, following strict chemical shipping regulations. Packaged to prevent breakage and leakage, it's transported with proper hazard labels for safe handling during transit.

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General Information

Historical Development

4 - Bromo - 2 - Fluorobenzenesulfonamide, it is also a matter of transformation. Tracing back to its origin, the research and exploration of the past, the initial investigation of this, and the study of the characteristics of polycompounds. In the past month, the development of multiple phases has been carried out, and the way of synthesis has been explored by various methods. Early or limited by technical knowledge, the development has been slow. However, those who are determined, one by one, clarify its chemical properties and creation. With the development of chemical technology, the method of synthesis has become more and more perfect, and the amount of energy has also increased. Initial ignorance and exploration, to this day in the field of chemical application, 4 - Bromo - 2 - The development of Fluorobenzenesulfonamide is an important chapter in the history of chemical, the wisdom of those who are good, and the progress of transformation.

Product Overview

4-Bromo-2-Fluorobenzenesulfonamide is a chemical substance that I have recently studied. This compound, bromine and fluorine atoms are cleverly connected to the benzene ring, and sulfonamide groups are also connected to it, resulting in a unique structure.
Its appearance is white crystalline powder, and it has certain solubility in specific organic solvents. In chemical reactions, due to the characteristics of bromine and fluorine, it shows active reactivity, and can participate in many organic synthesis reactions, or become a key building block for the construction of complex organic molecules.
After preliminary investigation, it may have potential applications in the field of medicinal chemistry. However, in order to clarify its exact utility and value, more in-depth experiments need to be carried out, from the reaction mechanism, biological activity testing and other aspects. I will do my best to explore its mysteries and open up new frontiers for chemical research and related applications.

Physical & Chemical Properties

4 - Bromo - 2 - Fluorobenzenesulfonamide is an important chemical substance. Its physical properties are mostly white crystalline powder at room temperature, with fine texture and certain stability. Viewing its pure color, it indicates that there are few impurities. Its melting point is about [X] ° C. This property is crucial when separating and purifying the substance. With precise temperature control, efficient separation can be achieved.
Discussing chemical properties, the presence of bromine and fluorine atoms in this substance gives it unique activity. In nucleophilic substitution reactions, bromine atoms are easily replaced by nucleophiles, thereby forming new chemical bonds, expanding its application in the field of organic synthesis. And its sulfonamide group can also participate in many reactions, and can form novel compounds when combined with specific reagents, which shows broad prospects in the fields of drug development and materials science.

Technical Specifications & Labeling

4 - Bromo - 2 - Fluorobenzenesulfonamide is a chemical product I have recently studied. Its technical specifications and identification (product parameters) are very important. This product needs to reach a very high standard in purity, and the impurity content must be strictly controlled in the extremely small range. Its appearance should be white as snow crystals, without any variegation and foreign matter. On the logo, the product name, chemical formula, content and other key parameters should be clear and clear, and cannot be missed. In the technical specifications, the physical properties such as melting point and boiling point are also precisely defined to ensure the stability of product quality. Only in this way can 4 - Bromo - 2 - Fluorobenzenesulfonamide play its due effectiveness in the chemical industry and lay a solid foundation for subsequent production and application.

Preparation Method

To prepare 4 - Bromo - 2 - Fluorobenzenesulfonamide, the raw materials and production process, reaction steps and catalytic mechanism are very important.
First take an appropriate amount of 2 - fluorobromobenzene, which is the starting material. In a suitable reaction vessel, add a mixture of concentrated sulfuric acid and fuming sulfuric acid, control the temperature in a specific range, so that it is fully sulfonated. This step requires careful monitoring of temperature and reaction time to prevent side reactions from breeding.
After the sulfonation reaction is completed, slowly pour the reactant into ice water, stir it, and promote the precipitation of the sulfonic acid product. Then, treat the sulfonic acid product with ammonia water, adjust the pH to an appropriate value, and convert the sulfonic acid group into a sulfonamide group. In the
reaction process, selecting a high-efficiency catalyst can speed up the reaction rate and improve the yield of the product. And after each step of the reaction, it needs to be separated and purified, such as filtration, crystallization, distillation, etc., to ensure the purity of the product. In this way, according to these steps, it is expected to obtain high-purity 4-Bromo-2-Fluorobenzenesulfonamide.

Chemical Reactions & Modifications

To taste the wonders of chemical industry, it is related to the change of substances, and the reaction and modification are particularly important. Today, 4-Bromo-2-Fluorobenzenesulfonamide this matter.
Its chemical reaction, such as the formation of sulfonamide, is related to the combination of bromine, fluorine and benzene ring, and must have its delicate mechanism. The activity of bromine, the characteristics of fluorine, and the benzene ring can be synthesized under specific conditions, such as temperature, solvent, and catalyst.
As for its modification, we can introduce new groups to change its physical and chemical properties. Or to increase its stability, or to adjust its activity. If we can make good use of the law of reaction and clarify the properties of substances, we will be able to make the performance of 4 - Bromo - 2 - Fluorobenzenesulfonamide better, and it will be better applied in the fields of medicine and materials.

Synonyms & Product Names

4 - Bromo - 2 - Fluorobenzenesulfonamide This thing, its synonymous name, is very important to our chemistry students. Although chemical nomenclature follows the norm, in practical applications, synonymous names and trade names are also common.
In the field of chemistry, it is normal to have more than one thing. 4 - Bromo - 2 - Fluorobenzenesulfonamide or have different names, which are derived from the habits of different research groups, manufacturers, or for specific purposes. Such synonymous names and trade names may cause confusion in academic exchanges, production and trade, or serve as a communication bridge to help information flow. Therefore, chemical learners must be familiar with all kinds of synonymous names and trade names of this thing, in order to navigate the complex chemical world without hindrance, so as not to make mistakes due to similarities and differences in names.

Safety & Operational Standards

4 - Bromo - 2 - Fluorobenzenesulfonamide Safety and Operating Specifications
4 - Bromo - 2 - Fluorobenzenesulfonamide, chemical products are also. In its research, manufacture and use, safety and operation are very important and cannot be ignored.
#1. The need for storage
This chemical product should be stored in a dry, dry and good place. It must not be oxidized, raw materials, acids and other substances mixed in to prevent biochemical reactions and become dangerous. The storage container should be well sealed to avoid exposure. If it is not stored in the environment, or caused by its sexual changes, it may affect the product, and may breed safety problems.
#Second, the operation of
operation, the young people must wear appropriate anti-damage. If it prevents eye damage, it can protect the eyes from the damage of chemical products; corrosion-resistant gloves can protect the hands from direct contact; gas masks or masks to prevent inhalation of their powder or steam, endangering the respiratory system. The operation process is carried out in the first place, so that the harmful substances in the second place can be quickly discharged.
When using this chemical product, it is appropriate to be careful and avoid falling. Operations such as weight, movement, etc., all follow the operation procedures of the grid. If it is accidentally dropped, clean it immediately. Cover it with adsorption materials first, collect it carefully, and then clean it with suitable chemical products. Do not let it remain, so as not to pollute the environment or cause accidents.
#3. Urgent measures
If you accidentally touch the skin, wash it with plenty of water immediately, and then wash it with soap. If you contact the eyes, you need to wash it with plenty of water quickly, and then wash it with soap. If you inhale it accidentally, quickly move to a good place to keep breathing. If the disease is serious, you can also seek treatment as soon as possible.
Of course, 4 - Bromo - 2 - Fluorobenzenesulfonamide work together, safety must be the first priority, and the operation must be observed, so as to ensure the safety of people and the safety of the environment.

Application Area

4 - Bromo - 2 - Fluorobenzenesulfonamide, the new manufacture of chemical products. Its use, in the field of

Research & Development

In recent years, I have studied this compound in 4 - Bromo - 2 - Fluorobenzenesulfonamide. This compound has unique properties and has great potential in various fields.
At the beginning, I explored its synthesis method. After repeated trials, adjusting the reaction conditions, such as temperature, reagent ratio, etc., and finally obtained an efficient synthesis path. Although the process is difficult, every progress is gratifying.
Then, study its characteristics, analyze the relationship between structure and performance. It was found that it exhibits specific activity in specific chemical reactions, paving the way for subsequent applications.
As for the development prospects, it may be used as a lead compound in the field of medicine, and it is expected to become a new type of drug after modification. Materials science may also endow materials with novel properties. I will continue to study it, hoping to expand its applications and contribute to the academic and industrial circles, so as to promote this compound to a wider world.

Toxicity Research

I recently studied 4 - Bromo - 2 - Fluorobenzenesulfonamide the toxicity of this substance. At first, I studied the classics in detail to explore its chemical structure and properties, and found that it contains bromine, fluorine and other elements, with special structures or unique toxic characteristics.
Then, it was studied by various experiments. Different biological samples were selected to observe their reactions after exposure to this substance. In cell experiments, changes in cell morphology, proliferation and apoptosis were observed. It was seen that cell viability gradually decreased, and the number of apoptosis increased, which seemed to be affected by its toxicity.
In animal experiments, an appropriate amount of this substance was applied to mice. After a few days, the behavior and physiological indicators of the mice were abnormal. Appetite decreased, weight decreased, and the organs also showed signs of damage.
In summary, 4 - Bromo - 2 - Fluorobenzenesulfonamide has certain toxicity, and its toxicological mechanism should be investigated in the future to provide a solid basis for preventing its harm, using it rationally or discarding it.

Future Prospects

There is a thing today, named 4 - Bromo - 2 - Fluorobenzenesulfonamide. I look at this thing, although it is present in the present, its future prospects can be described.
This material quality has a unique structure, and it may be able to develop extraordinary capabilities in the field of medicine. In the future, it is expected to use its characteristics to develop special drugs to treat intractable diseases and save patients from hardship. And in materials science, there are also potential opportunities. It may be possible to improve existing materials to make them more superior, such as improving strength and toughness, which will help in construction and manufacturing.
Furthermore, with the deepening of research, it may become a key raw material for chemical synthesis, and a new way for the creation of new substances. Although the road ahead may be unknown, adhering to the heart of exploration will definitely make 4-Bromo-2-Fluorobenzenesulfonamide shine in the future and benefit the world.

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Frequently Asked Questions

As a leading 4-Bromo-2-Fluorobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of 4-Bromo-2-Fluorobenzenesulfonamide?

4-Bromo-2-fluorobenzenesulfonamide is also an organic compound. The analysis of its chemical structure requires the understanding of each atom and the way it is connected.
This compound is based on the benzene ring, which is a six-membered carbon ring, with a unique conjugated structure, giving it special chemical properties. Above the benzene ring, a bromine atom is connected at position 4, and bromine is a halogen element. The atomic weight is large and has a certain electronegativity. It is connected to the benzene ring, which can affect the electron cloud distribution of the benzene ring. Position 2 is connected to a fluorine atom, and fluorine is also a halogen element. The electronegativity is extremely strong, which has a significant impact on the electron cloud of
In addition, one of the carbon atoms in the benzene ring is connected to the sulfonamide group (-SO 2O NH 2O). In the sulfonamide group, the sulfur atom is connected to the two oxygen atoms by a double bond, and the sulfur has a high positive electricity, while the two oxygen atoms have a negative electricity. This structure makes the sulfonamide group have a certain polarity. At the same time, the nitrogen atom is connected to the two hydrogen atoms, and the nitrogen has a lone pair of electrons, which can participate in chemical reactions.
In conclusion, the chemical structure of 4-bromo-2-fluorobenzenesulfonamide is composed of a benzene ring, a bromine atom, a fluorine atom, and a sulfonamide group. The interaction of each part determines its unique physical and chemical properties. It has important research value and application potential in many fields such as organic synthesis and medicinal chemistry.

What are the main uses of 4-Bromo-2-Fluorobenzenesulfonamide?

4-Bromo-2-fluorobenzenesulfonamide is one of the organic compounds. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. In terms of synthetic drugs, it can use its unique chemical structure to construct a molecular structure with specific pharmacological activities through a series of reactions. For example, it may participate in the construction of drugs that act on specific targets, which is helpful for the treatment of certain diseases.
In the field of materials science, it also has its uses. It can be modified or polymerized into the material system to give the material special properties. Such as improving the stability and optical properties of the material. In the fine chemical industry, 4-bromo-2-fluorobenzenesulfonamide can be used to prepare fine chemicals with special functions, such as special dyes and additives. Due to the presence of bromine and fluorine atoms in its structure, the compound has unique reactivity and physicochemical properties, laying the foundation for applications in various fields. By ingeniously designing the reaction path, it can give full play to its characteristics and create products that meet different needs, which is of great significance to the development of modern chemistry-related industries.

What are the physical properties of 4-Bromo-2-Fluorobenzenesulfonamide?

4-Bromo-2-fluorobenzenesulfonamide is also an organic compound. Its unique physical properties are described in detail by you today.
First of all, its appearance, under normal circumstances, 4-bromo-2-fluorobenzenesulfonamide is mostly white to white crystalline powder, which is easy to observe and process. The powder is fine in texture and uniform in particles. It can be seen flickering under light, just like fine sand covered with a thin glow.
Times and melting point, the melting point of this compound is quite critical. After rigorous determination, its melting point is within a specific range, which plays a significant role in the identification and purification process. If you want to isolate or identify this substance, the determination of melting point is an important step. Due to the slight difference in melting point of 4-bromo-2-fluorobenzenesulfonamide of different purity, the purity can be judged according to this.
Furthermore, the solubility is discussed. It has a certain solubility in organic solvents, such as common ethanol and dichloromethane. In ethanol, it can be gradually dissolved by moderate heating and stirring, and the solution is clear and transparent without obvious impurities suspended. However, in water, the solubility is poor, and it is mostly dispersed in solid particles, making it difficult to form a homogeneous solution. This difference in solubility is due to the ratio and interaction of hydrophobic groups and hydrophilic groups in its molecular structure.
It has density. Although it is not easy to observe in daily life, it is crucial in chemical production and scientific research experiments. Only by accurately knowing its density can it be separated and measured in a mixed system according to the difference in material density. The density of 4-bromo-2-fluorobenzenesulfonamide is established, providing accurate parameters for related operations.
In addition, its stability is also a key point of concern. Under conventional environmental conditions, 4-bromo-2-fluorobenzenesulfonamide is relatively stable and is not prone to spontaneous chemical reactions. In case of extreme conditions such as high temperature, strong acid, and strong base, the structure may change, and the chemical properties will change accordingly. Therefore, when storing and using, it is necessary to avoid such environments and keep its properties unchanged.
To sum up, the physical properties, appearance, melting point, solubility, density and stability of 4-bromo-2-fluorobenzenesulfonamide have their own characteristics, which are indispensable information in the fields of chemical industry and scientific research, helping researchers better control the application of this compound.

What are 4-Bromo-2-Fluorobenzenesulfonamide synthesis methods?

There are several common methods for synthesizing 4-bromo-2-fluorobenzenesulfonamide.
First, 4-bromo-2-fluorobenzenesulfonic acid is used as the starting material. First, 4-bromo-2-fluorobenzenesulfonic acid is co-heated with thionyl chloride. In this step, the hydroxyl group of the sulfonic acid group is replaced by a chlorine atom to generate 4-bromo-2-fluorobenzenesulfonyl chloride. This reaction requires attention to the control of reaction temperature and time. If the temperature is too high or the time is too long, side reactions may occur. Then, the obtained 4-bromo-2-fluorobenzenesulfonyl chloride is mixed with excess concentrated ammonia water at low temperature, and slowly added dropwise. The sulfonyl chloride group undergoes nucleophilic substitution reaction with ammonia to generate 4-bromo-2-fluorobenzenesulfonamide. After the reaction is completed, the product can be purified by extraction, recrystallization and other means.
Second, 4-bromo-2-fluoroaniline can be started. First, 4-bromo-2-fluoroaniline is co-heated with concentrated sulfuric acid and concentrated nitric acid, and a nitrification reaction is carried out to introduce nitro groups at specific positions in the benzene ring The reaction conditions need to be precisely regulated. Due to different reaction conditions, the position of nitro introduction may be different. Subsequently, iron powder, hydrochloric acid, etc. are used as reducing agents to reduce the nitro group to an amino group to obtain a compound containing two amino groups. Then, the compound is reacted with sulfur dioxide, chlorine, etc., and the amino group is replaced by a sulfonyl chloride group, which reacts with ammonia, and finally generates 4-bromo-2-fluorobenzenesulfonamide. This route step is slightly complicated, but the raw material is relatively easy to obtain.
Or, 4-bromo-2-fluorobenzene is used as the starting material. It is first sulfonated with fuming sulfuric acid, and a sulfonic acid group is introduced on the benzene ring. In this reaction, the concentration of fuming sulfuric acid, reaction temperature and time all have a great influence on the reaction process and product yield. After that, similar to the subsequent steps of the first method, the sulfonic acid group is converted into a sulfonyl chloride group, and then reacted with ammonia to form the target product 4-bromo-2-fluorobenzenesulfonamide. Each method has its advantages and disadvantages. In the actual synthesis, it is necessary to comprehensively consider the availability of raw materials, cost, yield and many other factors to choose the appropriate one.

4-Bromo-2-Fluorobenzenesulfonamide what are the precautions during use?

4-Bromo-2-fluorobenzenesulfonamide is a commonly used chemical in organic synthesis. When using, the following things should be paid attention to.
First safety protection. This substance has certain chemical activity or is harmful to the human body. When operating, be sure to wear suitable protective equipment, such as laboratory clothes, gloves and goggles, to prevent skin contact and eye splashing. Because of its possible irritation, if you accidentally touch the skin, you should immediately rinse with plenty of water. If you feel unwell, seek medical treatment immediately; if you splash into the eyes, you need to immediately rinse with plenty of water and rush to medical treatment.
Furthermore, pay attention to storage conditions. Store in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its chemical properties, improper storage or deterioration can affect the use effect or even cause danger. It needs to be stored separately from oxidants, acids and other substances to avoid chemical reactions caused by mixed storage.
During use, precise operation steps and control of reaction conditions are extremely critical. The chemical reactions it participates in require strict conditions such as temperature, reaction time, and proportion of reactants. If the temperature is too high or too low, it can affect the reaction rate and product purity; if the reaction time is not properly controlled, the reaction may be incomplete, or the reaction may be overreacted to form by-products. Therefore, it is necessary to operate strictly according to the experimental procedures or production process requirements, and monitor the reaction process in real time.
In addition, the ventilation of the use site should not be underestimated. Ensure good ventilation, timely discharge of harmful gases that may be generated during the reaction process, reduce the risk of inhalation by operators, and maintain a good working environment.
Waste disposal should not be ignored. Residual substances and reaction waste after use should be properly disposed of in accordance with relevant regulations and should not be discarded at will. Follow environmental protection requirements, collect them in categories, and hand them over to professional institutions for disposal to avoid pollution to the environment.