Hongda Chemical
Products
Home  /  Products  / 

4-Bromo-2-Fluoro-1-Methoxybenzene

4-Bromo-2-Fluoro-1-Methoxybenzene

Hongda Chemical

Specifications

HS Code

178961

Chemical Formula C7H6BrFO
Molecular Weight 205.02
Appearance Liquid (usually)
Boiling Point Around 195 - 200 °C
Density Data - specific density value may vary but typically in range for similar aromatic compounds
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
Flash Point Data - requires experimental determination
Vapor Pressure Low at room temperature
Odor Aromatic odor

As an accredited 4-Bromo-2-Fluoro-1-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - bromo - 2 - fluoro - 1 - methoxybenzene in a sealed, chemical - resistant bottle.
Storage 4 - bromo - 2 - fluoro - 1 - methoxybenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent evaporation and contact with air and moisture. Store it separately from oxidizing agents and reactive chemicals to avoid potential chemical reactions.
Shipping 4 - bromo - 2 - fluoro - 1 - methoxybenzene is shipped in well - sealed, corrosion - resistant containers. They are carefully packed to prevent breakage during transit and comply with all hazardous chemical shipping regulations.
Free Quote

Competitive 4-Bromo-2-Fluoro-1-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

4-Bromo-2-Fluoro-1-Methoxybenzene 4-Bromo-2-Fluoro-1-Methoxybenzene
General Information
Historical Development
4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene is also an organic compound. Tracing back to its origin, chemistry first emerged at an early age, and many sages worked hard to study it in the field of organic synthesis, unremitting exploration of new compounds. This compound, after years of pondering, chemists have used ingenious methods to adjust various elements to form this specific structure.
At that time, although the experimental conditions were not as complete as they are today, the perseverance of scholars has not been slightly reduced. After countless attempts, it was wrong and difficult, or the reaction temperature and the ratio of reactants were repeatedly weighed. Finally, this 4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene was obtained. Since its birth, it has gradually developed its use in various fields such as medicine and materials, contributing to the progress of scientific research, the rise of industry, and also opening up new paths for latecomers. Its historical evolution has witnessed the brilliance of chemistry and the spirit of unremitting exploration.
Product Overview
Today there is a substance called 4-Bromo-2-Fluoro-1-Methoxybenzene. Its shape is also an organic compound with a unique molecular structure. Bromine, fluorine, and methoxy are linked to each other at specific positions of the benzene ring to form this body.
The color of this substance may be colorless and transparent, or slightly colored, depending on its purity and preparation method. Smell, or have a specific smell, but the strength of its taste is also related to the environment and concentration.
In the field of chemical and pharmaceutical research and development, this compound is quite important. In the chemical industry, it can be used as a raw material to produce other types of organic products through various reactions. Pharmaceutical research and development, because of its special chemical properties, or can participate in the synthesis of pharmaceutical ingredients with specific curative effects, seeks human health and well-being. In chemical reactions, due to the characteristics of each atom and group, it shows unique reactivity, can react with many reagents, and derive a variety of products. The prospect is broad, and it is an important object of chemical research.
Physical & Chemical Properties
4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene is an organic compound, and its physicochemical properties are very important. Looking at its physical properties, at room temperature, this substance may be in a liquid state, with a specific color and odor. Its boiling point is related to its phase transition at different temperatures, which is of great significance for separation and purification. The melting point defines the transition temperature between its solid state and its liquid state.
Discuss the chemical properties, because it contains functional groups such as bromine, fluorine, and methoxy, and its chemical activity is unique. Bromine atoms can participate in nucleophilic substitution reactions, and fluorine atoms change the distribution of molecular electron clouds, which affects the reactivity. Methoxy groups have an electron supply effect, which affects the electron cloud density of the benzene ring, which in turn affects its electrophilic substitution reaction activity. This compound may have critical uses in the field of organic synthesis and can participate in many chemical reactions as an important intermediate to prepare more complex organic compounds.
Technical Specifications & Labeling
4-Bromo-2-fluoro-1-methoxybenzene is a chemical that we have been working on. Its process specifications and identification (product parameters) are crucial.
The preparation of this product requires strict procedures. From the selection of raw materials to the control of reaction conditions, it cannot be ignored. The purity of raw materials and the correct ratio are the basis for a smooth reaction. The reaction temperature and duration must also be precisely controlled to ensure the purity and yield of the product.
In terms of identification, the name, chemical formula, content and other parameters should be clearly marked. Packaging must be proper to prevent damage and leakage. Storage is also particular, choose a dry, cool place, avoid light and heat, and keep it stable. By strictly adhering to process specifications and labeling guidelines, 4-bromo-2-fluoro-1-methoxybenzene can be made of high quality and fully capable in applications.
Preparation Method
To prepare 4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene, the raw materials and production process, reaction steps and catalytic mechanism are crucial.
To prepare this compound, first take an appropriate amount of fluoroanisole as the starting material, based on the activity check point of its phenyl ring. Place it in a special reactor, add an appropriate amount of brominating reagent, such as liquid bromine, and add a specific catalyst, iron bromide is appropriate. Control the reaction temperature in a moderate range, about 50 to 60 degrees Celsius, which is a suitable thermal environment for the reaction.
During the reaction, bromine ions are induced by the catalyst to attack a specific position of the fluoroanisole phenyl ring, and through electrophilic substitution reaction, gradually generate the target product. This process requires close monitoring of the reaction progress, and timely regulation of the reaction conditions by means of high performance liquid chromatography to ensure the purity and yield of the product. After the reaction is completed, a series of separation and purification methods, such as extraction, distillation, recrystallization, etc., can obtain pure 4-Bromo-2-Fluoro-1-Methoxybenzene. This preparation method, with reasonable raw materials, precise steps and effective catalysis, achieves the purpose of preparation.
Chemical Reactions & Modifications
Wen 4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene, in the field of chemistry, its reaction and modification are very important. In the past, the researchers worked hard to understand the effect of its transformation.
At the beginning, it was tried by the usual method, but the effect was not good, the yield was quite low, and there were many impurities. The public then thought about changes, observed its structure, and studied its characteristics. Or adjust the temperature, or change the agent, and apply it in a hundred ways.
A new method was obtained, and a certain agent was used to accompany it, the temperature was controlled at an appropriate value, and the reaction was smooth. The yield gradually increased, and the quality was also excellent. This change is not only the progress of skills, but also the fruit of deep understanding of chemical properties.
Looking at its modification, after various attempts, new bases are introduced, and chemical properties are one of the changes. It has a wide range of uses, and it has a new look in the fields of medicine and materials. From this perspective, chemical application and modification are actually the Jinliang of chemical research, and continuous exploration can achieve a good state.
Synonyms & Product Names
4-Bromo-2-fluoro-1-methoxybenzene is also an organic compound. Its synonyms and trade names are quite important in the field of chemical industry.
There are many synonyms for this substance, or from its structural characteristics, or according to the naming method of the past, there are many names. And the trade name is the name chosen by the merchant to recognize its characteristics and facilitate its sale.
In the process of my chemical research, I know that although different synonyms and trade names refer to the same thing, in the context of literature records and experimental exchanges, if the details are not known, it is easy to cause confusion and make mistakes. It is to examine its synonyms and trade names in detail, which can make the research more smooth and accurate. And when it is industrially prepared and circulated in the market, it is also necessary to clarify its different names in order to make everything orderly and not disordered. Therefore, it is of great significance to explore the synonyms and trade names of 4-bromo-2-fluoro-1-methoxybenzene in chemical research and related industries.
Safety & Operational Standards
4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene Safety and Handling Specifications
Fu 4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene is a chemical commonly used in organic synthesis. To handle this product safely, it is necessary to understand its characteristics and follow its specifications.
This product has certain chemical activity and should be protected first during operation. The operator wears protective gloves in front of suitable protective clothing to prevent skin contact with it. Because it may be irritating, touching the skin can cause discomfort or even damage. You also need to wear goggles to protect your eyes from splashing into the eyes and causing eye diseases.
It is essential to operate in a well-ventilated place. This substance may evaporate harmful gases. If the space is blocked, the gas will accumulate, and inhalation will damage the respiratory tract, and even endanger the health of the whole body. Therefore, the fume hood is a necessary appliance, which can quickly discharge harmful gases and ensure the safety of the operating environment.
Furthermore, storage also has its own rules. When placing 4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene in a cool, dry place, away from fire and heat sources. Cover it in case of heat or open flame, and it should be stored separately from oxidizing agents, acids, alkalis, etc., to avoid chemical reactions caused by improper mixing and lead to accidents.
During the operation, take an appropriate amount, do not take more waste, and prevent accidents caused by excess. If it is accidentally spilled, clean it up immediately. Small spills can be absorbed by inert materials such as sand and vermiculite, placed in suitable containers, and disposed of according to regulations. If a large number of spills need to start an emergency plan, evacuate personnel, seal the scene, and properly dispose of it by professionals.
Operate 4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene, take safety as the priority, and abide by the operating specifications, so as to avoid disasters, ensure the smooth operation of the experiment, and protect the health of the personnel.
Application Area
4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene is a delicate chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new specific drugs to cure various diseases. In the field of materials science, it also has important functions, and may be used to prepare materials with special properties, such as materials with high stability and high conductivity, thus promoting progress in this field. In the field of fine chemicals, this substance can be used to synthesize special additives, improve product performance and improve product quality. Looking at its application, it covers many important fields and is of great value in promoting the development of various fields. It is an indispensable part of chemical research and industrial production.
Research & Development
In recent years, I have been in the field of organic chemistry, specializing in the study of 4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene. At first, analyze its structure, clarify its characteristics, and understand the wonder of its reaction mechanism.
Study its synthesis method, and try all kinds of things. Either adjust the temperature of the reaction, or change the amount of reagents, or change the choice of solvents, hoping to obtain the best method. Beginning with the conventional method, the yield did not meet expectations. Later, the new theory was introduced, and the technique of catalysis was tried, and it has made progress.
Re-explore its application, and in the preparation of pharmaceuticals, it can be used as a key intermediate, paving the way for the development of new drugs. In the field of materials science, it also has potential value and is expected to create materials with special properties.
Although it has been achieved, the road ahead is still difficult. To increase productivity, reduce costs, and expand applications. I must study diligently, hoping that this product can shine in scientific research and industry, and contribute to the development of chemistry.
Toxicity Research
Toxicity of 4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene. The toxicity of this product is related to people's livelihood and health, and cannot be ignored.
Examine the properties of this chemical in detail. Its structure is unique, bromine, fluorine and methoxy are combined in the benzene ring. Such structures may cause it to have special reactivity, and the activity is often related to toxicity.
According to common sense, halogen atoms such as bromine and fluorine may increase their lipid solubility, easily penetrate biofilms, enter cells, and disrupt their biochemical order. Although methoxy may have the effect of regulating charge distribution, on the whole, this product may interfere with the metabolic pathway of organisms.
Looking at the examples of similar structural chemicals in the past, most of them have the ability to affect nerve conduction and damage liver and kidney. Therefore, it is speculated that 4-Bromo-2-Fluoro-1-Methoxybenzene may also have such potential toxicity. Strict experiments are required to determine the degree of harm to life and provide a solid basis for future application and protection.
Future Prospects
Today 4 - Bromo - 2 - Fluoro - 1 - Methoxybenzene This product has extraordinary potential in the field of chemistry. Although the current production is limited, the future development can be looked forward to.
We research it, hoping to use new technologies to increase its yield and improve its purity. In the future, it may be widely used in the manufacture of medicine, with its unique properties, to make special drugs and solve people's diseases. Or in the world of materials, it will shine brightly, providing a solid foundation for the research of new materials.
With time and unremitting efforts, its potential will be fully developed. To make this compound successful in all fields and for the benefit of future generations is our vision for the future.
Where to Buy 4-Bromo-2-Fluoro-1-Methoxybenzene in China?
As a trusted 4-Bromo-2-Fluoro-1-Methoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Bromo-2-Fluoro-1-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Bromo-2-Fluoro-1-Methoxybenzene?
4-Bromo-2-fluoro-1-methoxybenzene is also an organic compound. It has a wide range of uses and plays an important role in the field of organic synthesis.
First, it can be used as a pharmaceutical intermediate. To cover the process of pharmaceutical synthesis, it is often necessary to construct a specific molecular structure. 4-bromo-2-fluoro-1-methoxybenzene can be used as a key building block because of its unique chemical structure. Through various chemical reactions, such as nucleophilic substitution, coupling reaction, etc., other functional groups are introduced to synthesize compounds with specific pharmacological activities, laying the foundation for the creation of new drugs.
Second, it is also used in the field of pesticides. It can participate in the synthesis of pesticides with high insecticidal, bactericidal or herbicidal properties. It is chemically modified to make it highly selective and active to specific pests or weeds, improve the efficacy of pesticides, and reduce the adverse effects on the environment.
Third, it can also be seen in materials science. It can be used as a starting material for the synthesis of special functional materials. After polymerization or other reactions, materials with special optical, electrical or thermal properties are prepared for use in electronic devices, optical instruments and many other aspects.
Furthermore, this compound is also an important tool in scientific research and exploration. Chemists can gain in-depth insight into the mechanism of organic reactions by studying their reactivity, expand the knowledge system of organic chemistry, and provide ideas and basis for the development of new reactions and new synthesis methods.
In short, 4-bromo-2-fluoro-1-methoxybenzene has important uses in many fields such as medicine, pesticides, materials and scientific research due to its unique structure and chemical properties, promoting the development and progress of related fields.
What are the physical properties of 4-Bromo-2-Fluoro-1-Methoxybenzene?
4-Bromo-2-fluoro-1-methoxybenzene is one of the organic compounds. Its physical properties can be described in detail.
First of all, its appearance, at room temperature and pressure, is mostly colorless to light yellow liquid, clear and transparent, like the purity of morning dew. Its smell, often with a special aroma, but not a rich and strong fragrance, is elegant and unique, and the smell is slightly impressive.
As for the boiling point, it is about a certain numerical range. Due to the intermolecular force, it needs to supply a considerable amount of energy before it can be converted from liquid to gas. Specifically, its boiling point varies slightly according to the experimental conditions, and is probably in a certain range. This is due to the interaction of bromine, fluorine and methoxy groups in the molecular structure, which affects the attractive force between molecules, and then determines the energy required for boiling.
Melting point is also an important physical property. The melting point of 4-bromo-2-fluoro-1-methoxylbenzene allows this substance to maintain the stability of the solid state at a specific temperature limit. The definition of this temperature is dominated by the molecular arrangement and interaction forces. In the solid state, the molecules are arranged in an orderly manner and have a tight structure.
In terms of solubility, this substance exhibits good solubility in organic solvents, such as some common ether and aromatic hydrocarbon solvents. Due to the principle of "similarity and dissolution", the molecular structure of its organic molecules is similar to that of organic solvents, and they can form a weak interaction with each other, thus dissolving with each other. However, in water, due to the hydrophobicity of the molecule, the solubility is quite low, and the force between the water molecule and the compound molecule is weak, making it difficult to disperse it uniformly in water.
Density is also a property that cannot be ignored. Its density is slightly heavier than that of water, so if mixed with water, this substance will sink to the bottom of the water. This is because the relative weight of the bromine atom in the molecule is relatively large, resulting in an increase in the overall molecular weight, which in turn affects its density. The physical properties of 4-bromo-2-fluoro-1-methoxybenzene are due to its unique molecular structure. The interaction between atoms and functional groups jointly determines its various manifestations in the physical world.
What are 4-Bromo-2-Fluoro-1-Methoxybenzene synthesis methods?
The synthesis method of 4-bromo-2-fluoro-1-methoxybenzene has been recorded in many books in the past, and this is a detailed description for you.
First, the method of using phenolic compounds as starting materials. First take specific phenols and make them react with halogenating reagents such as brominating agents and fluorinating agents in sequence. During bromination, it is necessary to choose appropriate reaction conditions, control temperature, time and reagent dosage, so that bromine atoms precisely replace hydrogen atoms at specific positions in the benzene ring. After fluorination, the reaction parameters are also carefully adjusted to allow fluorine atoms to be introduced. Finally, the methoxylation reaction is carried out with methylating reagents, such as dimethyl sulfate, etc., to complete the introduction of methoxy groups under the catalysis of bases, so as to obtain the target product 4-bromo-2-fluoro-1-methoxybenzene.
Second, based on the synthesis path of halogenated aromatics. Select suitable halogenated aromatics and pass through metal-catalyzed coupling reactions, such as palladium-catalyzed reactions. First, the halogenated aromatics are coupled with fluorinated reagents in the presence of palladium catalysts, ligands and bases to construct fluorophenyl ring structures. Then bromine atoms are introduced, and brominating reagents can be used to react under appropriate conditions. Finally, 4-bromo-2-fluoro-1-methoxybenzene is formed by reagents such as iodomethane and corresponding intermediates through methoxylation steps.
Third, the functional group conversion method of benzene ring derivatives is used. Take benzene ring derivatives containing suitable substituents and protect or activate some groups first. Bromine, fluorine and methoxy groups are introduced in sequence through multi-step reactions such as oxidation, reduction and substitution. This process requires fine design of the reaction sequence and conditions to ensure the selectivity and yield of each step of the reaction, and finally obtain the required 4-bromo-2-fluoro-1-methoxybenzene.
The above synthesis methods have their own advantages and disadvantages, and the experimenter should choose carefully according to factors such as their own needs, availability of raw materials, and reaction conditions.
4-Bromo-2-Fluoro-1-Methoxybenzene need to pay attention to when storing
For 4-bromo-2-fluoro-1-methoxybenzene, many things need to be paid attention to when storing. This compound has specific chemical properties, so it should be placed in a dry place. Moisture can easily cause it to deteriorate. If the environment is humid, or it causes reactions such as hydrolysis, it will damage its purity and quality.
Furthermore, temperature is also critical. It should be stored in a cool place to avoid high temperature hot topics. If the temperature is too high, it may promote its chemical reaction, cause decomposition or other adverse changes. Generally speaking, an environment at room temperature or slightly below room temperature is appropriate.
It is also indispensable to keep it away from light. Under light, this compound may have photochemical reactions, which affect its stability. Choose brown bottles and other dark containers to prevent light intrusion.
In addition, 4-bromo-2-fluoro-1-methoxybenzene may be toxic and irritating. Store away from people and food, and clearly marked to make others aware of its danger. When taking it, follow strict operating procedures to ensure safety.
Store in a place that should also be well ventilated to prevent the accumulation of volatile gases and reduce latent risk. At the same time, store separately from other chemicals to avoid mutual reaction.
In conclusion, in order to properly store 4-bromo-2-fluoro-1-methoxybenzene, it is necessary to pay attention to drying, temperature, protection from light, safety and ventilation, so as to ensure its quality and stability.
What is the market price of 4-Bromo-2-Fluoro-1-Methoxybenzene?
4-Bromo-2-fluoro-1-methoxybenzene is one of the organic compounds. Its market price is difficult to determine, and it is subject to many factors.
First, the cost of raw materials is related to its price. The preparation of this compound requires raw materials such as bromide, fluoride and methoxylation reagents. If the supply of raw materials is abundant and the price is stable, the cost of 4-bromo-2-fluoro-1-methoxybenzene may be controlled; however, if the supply of raw materials is scarce, or its price rises sharply due to market supply and demand, changes in origin, etc., the cost of 4-bromo-2-fluoro-1-methoxybenzene will increase, and its market price will also rise.
Second, the preparation process is also the key. Preparation of 4-bromo-2-fluoro-1-methoxybenzene, or there are various process paths. An efficient, simple and high-yield process can reduce its production cost; if the process is complicated, special equipment is required, harsh reaction conditions are required, or the yield is low due to many reaction steps, the production cost will be high and the market price will be high.
Third, the supply and demand situation of the market has a great impact on the price. If an industry has strong demand for 4-bromo-2-fluoro-1-methoxybenzene, but limited supply, its price is bound to rise; conversely, if the market demand is low and the supply is excessive, the price may be downward.
Fourth, the level of purity is also related to the price. The high purity of 4-bromo-2-fluoro-1-methoxybenzene is often higher than that of ordinary purity due to the difficulty of preparation and the high requirements for purification process.
In summary, due to the above factors intertwined, the market price of 4-bromo-2-fluoro-1-methoxybenzene is difficult to say exactly, or varies from time to time, and it is difficult to give a fixed value.