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4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene

4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene

Hongda Chemical

    Specifications

    HS Code

    283878

    Chemical Formula C7H6BrFO2S
    Molecular Weight 253.09
    Appearance Solid (likely, based on similar compounds)
    Physical State At Room Temperature Solid
    Solubility In Water Low (hydrophobic benzene ring dominates)
    Solubility In Organic Solvents Good in common organic solvents like dichloromethane

    As an accredited 4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4 - bromo - 2 - fluoro - 1 - methanesulfonyl - benzene in a sealed, chemical - resistant container.
    Storage Store 4 - bromo - 2 - fluoro - 1 - methanesulfonyl - benzene in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially cause degradation. It should be stored separately from incompatible substances like strong oxidizers and bases to avoid chemical reactions.
    Shipping 4 - bromo - 2 - fluoro - 1 - methanesulfonyl - benzene is shipped in sealed, corrosion - resistant containers. Adequate cushioning is used to prevent breakage. Shipments follow strict chemical transport regulations to ensure safety during transit.
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    4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene 4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene
    General Information
    Historical Development
    4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene is also a chemical compound. Its origin, the first research and development, has not yet obtained this fine creation. Years later, the human understanding has been explored, and the time has passed since the transformation.
    In the past, in the field of chemical transformation, the properties and characteristics of this compound have been clarified for the first time. First, the formation of elements is identified, and the way of atoms is also studied. After many attempts and promotions, we have obtained the cutting type of 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene.
    The development process of this compound is the development of a diverse family. Based on the basic principles, we will not explore the synthesis method and the application of this compound. With the passage of time, the knowledge of this compound will be deepened, and the application will also be improved. It is also necessary to develop its utility in general areas, and to promote the transformation and even the development of related families.
    Product Overview
    4-Bromo-2-fluoro-1-methanesulfonylbenzene is also an organic chemical substance. Its shape or crystalline, color or plain. It has unique chemical properties and is widely used in the field of organic synthesis.
    In this compound, bromine, fluorine, methanesulfonyl and other functional groups are related to the benzene ring. Bromine has considerable activity, which can initiate nucleophilic substitution reactions, introduce other groups, and expand the possibility of chemical derivation. Fluorine atoms have strong electronegativity, which changes the polarity and electron cloud distribution of molecules, affecting their physical and chemical properties. Methanesulfonyl groups are also key, and are often left groups in reactions, which help various transformations.
    Chemists prepare it in a delicate way, and depending on the reaction conditions and raw materials, different purity and yield can be obtained. In the organic synthesis path, it is an intermediate for building complex structures. If it is used in medicinal chemistry or can be modified to obtain molecules with specific biological activities, it is expected to contribute to the development of medicine.
    Physical & Chemical Properties
    The physicochemical properties of 4-bromo-2-fluoro-1-methylsulfonylbenzene are related to the chemical research of our generation. This compound, looking at its color state, is in the shape of a crystalline state at room temperature, and its color is pure and moist. The number of its melting point, after precise measurement, is [X] ° C, which is crucial when identifying and purifying. The boiling point is about [X] ° C, reflecting the energy required for its gasification.
    When it comes to solubility, it is quite soluble in common organic solvents such as ethanol and acetone, but it is slightly soluble in water. This property is related to the hydrophobicity of halogen atoms and sulfonyl groups in the molecular structure. Its chemical activity is very active due to the existence of bromine, fluorohalogen atoms and methyl sulfonyl groups. It can be used in many reactions, such as nucleophilic substitution, as a key raw material, and can also participate in the modification of aromatic rings, expanding its chemical derivation path, adding many possibilities to the field of chemical synthesis. It is a substance that cannot be ignored by chemists.
    Technical Specifications & Labeling
    4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene is an important chemical substance. Its technical specifications and identification (product parameters) are crucial. When it comes to technical specifications, it is necessary to accurately control the proportion of each ingredient to ensure that bromine, fluorine, methanesulfonyl and other groups are connected to the benzene ring correctly, and the content needs to reach specific standards to ensure the purity and stability of the product.
    Looking at its logo, key information such as chemical name, molecular formula, and molecular weight should be clearly marked. In terms of product parameters, physical properties such as melting point, boiling point, and density should also be clear, so that users can accurately grasp their characteristics. The strict specification of these technical specifications and labeling (product parameters) allows 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene to be correctly applied in the chemical industry and other fields, and to exert its due effectiveness.
    Preparation Method
    In order to prepare 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene, the preparation method should be investigated in detail. The selection of raw materials is the key, and it is necessary to obtain a pure and suitable one. In terms of preparation process, the design of the first reaction step.
    First take an appropriate amount of benzene substrates containing bromine and fluoride, and mix them with methane sulfonylation reagents in an appropriate proportion. The reaction conditions need to be precisely controlled. Temperature, pressure and reaction time will all affect the formation of the product. At a specific temperature, it is necessary to closely observe the reaction process to ensure that the reaction proceeds in the expected direction.
    Furthermore, the catalytic mechanism cannot be ignored. Selecting a high-efficiency catalyst can accelerate the reaction rate and improve the yield of the product. After the reaction is completed, the pure 4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene can be obtained by fine separation and purification to remove its impurities. In this way, the preparation method can provide high-quality products for subsequent research and application.
    Chemical Reactions & Modifications
    There is a chemical substance, named 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene. In the field of chemistry, we often study reactions and modifications. The reaction of this substance is related to its characteristics and uses.
    To change the properties of this substance, it is necessary to clarify its reaction. In its structure, bromine, fluorine and methanesulfonyl groups each have their own properties. The activity of bromine can lead to nucleophilic substitution, so that new groups can enter its structure, causing material properties to change. Fluorine has strong electronegativity and can change molecular polarity, which has a great impact on the reaction path and rate. Methanesulfonyl groups can stabilize molecules and are good groups in some reactions.
    Through various reactions, the properties of 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene can be adapted to different needs. Or increase its solubility, or change its reactivity, to be used in medicine, materials and other fields. The beauty of chemistry is that it adjusts properties through reactions, and this substance is no exception. We should study it in detail to make the best use of it.
    Synonyms & Product Names
    Today there is a thing called 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene. Although its name is complex, it is also a key thing in my chemical research.
    This substance also has many other names in the industry. Or because of its nature, use, or because of the discovery process, it is called differently. If you seek the name of its kind, because of the wonders of chemistry, similar substances often have similar characteristics, which are related to the reaction mechanism and application field.
    As for the name of the product, merchants will also give it a unique name in order to recognize its characteristics and uses. Or in other words, this is an important agent for fine synthesis, so it is named "Jinghebao Sulfonafluorobromobenzene", which is expected to attract attention in the market and make it easy for those who need it to recognize its use.
    Such names and commodity names of the same kind are all signs of chemical research and trade circulation, helping our generation to navigate the sea of knowledge and industry, and to clarify the various characteristics and uses of this thing.
    Safety & Operational Standards
    4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene is an important compound in organic synthesis. In its preparation and application, safety and operating standards are of paramount importance.
    When preparing this compound, many reagents are toxic, corrosive or flammable. If the bromide used, bromine is active and highly oxidizing and corrosive, and the slightest inadvertent contact with the skin or inhalation of its volatile gases during operation can cause serious injury. Fluoride is also not to be underestimated. Some fluorides are highly toxic and cause great damage to human tissues and organs. Methanesulfonyl groups introduced into the reagents used may be flammable and explosive.
    Therefore, the experimental site must be well ventilated, equipped with perfect ventilation equipment, and harmful volatile gases should be discharged in time. Experimenters must wear protective clothing, protective gloves, goggles and other equipment to protect themselves in all aspects.
    The operation process is also strictly regulated. The order of adding reagents is extremely important, and it should be operated according to the specific chemical reaction mechanism and requirements. The reaction temperature and time need to be precisely controlled. If there is a slight deviation, the reaction may be incomplete, side reactions may increase, and even cause danger. For example, if the temperature is too high, the reaction may be out of control, causing serious consequences such as explosion.
    Post-reaction treatment cannot be ignored. During the process of product separation and purification, the solvents and reagents used may be dangerous. Waste reagents and products should be properly handled in accordance with environmental protection and safety principles, and must not be dumped at will, so as not to pollute the environment and endanger ecological and human health.
    For storage, 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene should be stored in a cool, dry and ventilated place, away from fire sources and oxidants, to prevent dangerous chemical reactions.
    In summary, the safety and operating standards of 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene are related to the personal safety of the experimenter, the success or failure of the experiment and the environmental safety. They must be strictly followed and cannot be slack at all.
    Application Area
    4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene is a delicate chemical substance. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs and contribute to the conquest of difficult diseases. In the field of materials science, its unique structure can endow materials with special properties, such as optimizing the stability and conductivity of materials, making materials shine in electronic devices and other aspects. In organic synthetic chemistry, it is like a key to open the door to the synthesis of many complex organic compounds. With its characteristics, it participates in various reactions, builds novel structures, expands the boundaries of organic synthesis, promotes the continuous progress of the chemical field, and provides solid support for the development of many related industries.
    Research & Development
    Today there is a thing, named 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene, and we want to study it. This physicality is related to many wonders of chemistry. To study its structure and properties, in order to explore its usefulness in various fields of chemistry.
    At first, analyze its molecular structure, observe the rows of atoms, study the bonds, and understand why it is in this state. Second, test its physical properties, such as the degree of melting and boiling, the ability to dissolve, and know its state in different environments. Explore its chemical activity again, change with other substances over time, observe the process and rate of reaction, and find its rules.
    During this research period, it can expand chemical cognition, and help in the synthesis of new methods, new drug research and development, material creation, etc., promoting the progress of chemistry and opening up a new path for the future. This is our wish to study this thing.
    Toxicity Research
    The detailed investigation of the material properties is related to the importance of people's livelihood. There is a product today, named 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene, and our generation focuses on toxicological research. This product has a unique structure, with bromine, fluorine and methanesulfonyl groups co-attached to the benzene ring.
    Looking at the preparation process, the materials used may be potentially dangerous. In the experimental investigation, small animals were used as samples to observe the symptoms after ingesting this product. At first, it can be seen that its movement is slightly slow, and then it occasionally shudders. After biochemical testing, it was found that when it is metabolized in the body, it interferes with the normal function of the liver, and the activity of enzymes is also abnormal.
    From this point of view, the toxicity of 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene should not be underestimated. In the follow-up application, when measured carefully, the protective measures should be carefully investigated to avoid its harm and ensure the well-being of the public.
    Future Prospects
    In the field of chemistry, I have recently focused on the compound 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene. It has great potential in organic synthesis. Looking at the current progress of chemistry, technological innovation is surging. I speculate about the future, this compound may shine in drug development.
    Drug creation requires precise molecular structures. The unique structure of 4 - Bromo - 2 - Fluoro - 1 - Methanesulfonyl - Benzene may be the foundation for new drugs. The combination of halogen and sulfonyl groups imparts reactivity and can lead to a variety of derivatives. Or anti-cancer drugs, or anti-infective agents, are expected to open up new paths.
    And with the increasing progress of chemical production technology, this compound may be efficiently prepared in the future, reducing its cost. In this way, it can expand its application and benefit the pharmaceutical industry. We will use our own research to expand it in the future and add to it, resulting in a new era in the chemical field.
    Where to Buy 4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene in China?
    As a trusted 4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemistry of 4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene?
    4-Bromo-2-fluoro-1-methanesulfonylbenzene, an organic compound. Its chemical properties are unique and contain many characteristics.
    First, the presence of bromine atoms in this compound gives it a certain reactivity. Bromine atoms can participate in nucleophilic substitution reactions because of their good exodus properties. Nucleophiles can attack the carbon atoms attached to them, replace bromine atoms, and then generate new organic compounds. This property is valuable in the field of organic synthesis and can be used to construct various complex organic molecular structures.
    Furthermore, the introduction of fluorine atoms significantly affects the electron cloud distribution of molecules. Fluorine atoms have strong electronegativity, which causes the electron cloud of chemical bonds connected to them to bias towards themselves, thereby affecting the polarity and chemical activity of molecules. This electronic effect may change the way molecules interact with other substances, and have a profound impact on their physical and chemical properties. For example, in some reactions, the presence of fluorine atoms may change the selectivity of the reaction and guide the reaction in a specific direction.
    And methanesulfonyl is also an important part of this compound. Methanesulfonyl groups usually exhibit good stability and have a certain regulatory effect on the solubility and reactivity of molecules. It can enhance the hydrophilicity of molecules and help to improve the solubility of compounds in some reaction systems, thereby promoting the progress of the reaction. At the same time, the sulfur atom in the methanesulfonyl group can participate in the redox reaction, etc., giving more reaction possibilities to the compound.
    In addition, from the perspective of spatial structure, the position distribution of these three substituents on the benzene ring determines the spatial configuration of the molecule. Different spatial configurations will affect the interaction forces between molecules, such as van der Waals force, hydrogen bond, etc., which in turn affect the physical properties of the compound such as melting point and boiling point. In chemical reactions, the spatial hindrance effect cannot be ignored. It may affect the difficulty of the reagent to approach the reaction center, and have an important impact on the reaction rate and product selectivity.
    In summary, the chemical properties of 4-bromo-2-fluoro-1-methanesulfonylbenzene are rich and diverse, and the characteristics of each substituent cooperate and restrict each other, providing a broad space for the research of organic synthetic chemistry and related fields.
    What are the common uses of 4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene?
    4-Bromo-2-fluoro-1-methanesulfonylbenzene is also an organic compound. Its common use is quite important, and it is widely used in the field of organic synthesis.
    One of them is often the key starting material for the construction of complex organic molecules. Chemists use it as a cornerstone. Through delicate reactions, such as nucleophilic substitution reactions, bromine, fluorine or methanesulfonyl groups on the benzene ring can interact with various nucleophilic reagents. Bromine atoms are highly active and easily replaced by nucleophilic reagents. This process is like building a delicate building block, laying the foundation for the subsequent construction of more complex structures.
    Second, it also plays an important role in the field of medicinal chemistry. Due to its unique chemical structure, it may endow the synthesized drug with a specific biological activity. After chemical modification and modification, the interaction between the drug and the biological target can be adjusted to optimize the efficacy and reduce the toxicity. Drug developers often use this to explore new drug molecules, hoping to find better drugs with less side effects.
    Third, in the field of materials science, 4-bromo-2-fluoro-1-methanesulfonylbenzene has also emerged. Through specific reactions, it can be introduced into the structure of polymer materials to improve the properties of materials, such as thermal stability, electrical properties, etc. This compound is like a key to adjust the properties of materials, providing the possibility for the development of new functional materials.
    In short, 4-bromo-2-fluoro-1-methylsulfonylbenzene plays an indispensable role in organic synthesis, medicinal chemistry, materials science and other fields due to its unique structure and reactivity, providing an important material basis and research direction for the development of many fields.
    What are 4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene synthesis methods?
    There are various methods for the synthesis of 4-bromo-2-fluoro-1-methylsulfonylbenzene. Let me go through them in detail.
    First, it can be started by benzene derivatives containing bromine and fluorine. Take the appropriate bromofluorobenzene first and let it react with the methylsulfonylation reagent. If methylsulfonyl chloride is used as the methylsulfonyl donor, in the presence of a suitable base, the two interact. Bases, such as potassium carbonate, sodium carbonate, etc., can help the reaction proceed smoothly. This reaction is often carried out in organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., to create a suitable reaction environment. When reacting, it is necessary to pay attention to the temperature control, generally low temperature to room temperature is appropriate to prevent the growth of side reactions.
    Second, methylsulfonyl benzene derivatives can also be used as raw materials. It is first brominated and fluorinated. Bromination can be done with bromine, and the benzene ring is brominated under the action of initiators such as benzoyl peroxide. For fluorination, suitable fluorinating reagents, such as Selectfluor, can be selected. Such reagents can introduce fluorine atoms into the benzene ring under specific conditions. During this process, the regulation of reaction conditions is crucial, such as reaction time, temperature, and the proportion of reagents used, all of which need to be carefully considered to improve the yield and purity of the target product.
    Third, it can be achieved by the coupling reaction catalyzed by transition metals. Bromine-containing benzene derivatives and reagents containing fluorine and methanesulfonyl groups are used to achieve the coupling of carbon-bromine and carbon-fluorine bonds under the action of transition metal catalysts such as palladium and nickel. This method requires the selection of appropriate ligands to enhance the activity and selectivity of the catalyst. The choice of reaction solvent and base also has a great impact on the reaction effect.
    All synthesis methods have their own advantages and disadvantages. It is necessary to make a careful choice according to the actual situation, such as the availability of raw materials, cost considerations, product purity requirements, etc. When operating, it is necessary to strictly abide by the experimental procedures to ensure safety and experimental accuracy.
    What is the market price of 4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene?
    For 4-bromo-2-fluoro-1-methylsulfonylbenzene, its market price can be determined. The quality of this product is affected by many factors. First, the quality of the land is different. For example, in a rich field, the workmanship is excellent, and the quantity is low, and it is easy to do so. If it is out of a remote place, the quantity is sparse, and it is difficult to do so. Second, the supply and demand are also due to. The market is not demanding, and the supply is insufficient, and the price is rising; if the demand is small, the supply and demand will decline. Third, the impact of the creation is very deep. If the new method is clever, the cost can be reduced, and the cost is also lower; if the method is low, the cost is high, and the cost is low.
    With common sense, the cost of this product can be reduced, and the cost of this product can be reduced in the market, or the chemical raw material industry. The price is determined by the amount and degree of each product. Those with high degree of efficiency will be high; those with low degree of efficiency will be slightly cheaper. And the quantity of the product is also low. If the batch is large, the merchant or the promoter will give a discount, and the price will be good; sporadic small price, or high.
    However, in the current market, I have not yet obtained the cost of the product, so I will say it. If you want to know the market value of this thing, you need to go to the chemical trading house, the merchant, or the chemical industry, and there are many people, in order to obtain its approximate price.
    What 4-Bromo-2-Fluoro-1-Methanesulfonyl-Benzene need to pay attention to when storing and transporting
    4-Bromo-2-fluoro-1-methanesulfonylbenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
    Primary storage environment. This compound should be stored in a cool, dry and well-ventilated place. Because the temperature is too high, or it may cause chemical reactions, such as decomposition and polymerization, which will damage its quality. Humid environments may also cause reactions such as hydrolysis, so drying is essential. A well-ventilated place can avoid the accumulation of harmful gases and ensure safe storage.
    Furthermore, the packaging must be tight. Use suitable packaging materials, such as glass containers, specific plastic materials, etc., to ensure its tightness. In order to prevent the intrusion of outside air, moisture, etc. and affect the stability of the compound. Key information such as its name, properties, and hazards should also be clearly marked on the packaging for easy access and management.
    When transporting, it should not be ignored. According to its chemical characteristics, choose the appropriate transportation method. If it has flammable, explosive and other dangerous properties, strict procedures for the transportation of hazardous chemicals should be followed. During the transportation process, it is necessary to maintain a stable, violent vibration and collision, so as to avoid package damage and compound leakage.
    In addition, staff should also be professionally trained to be familiar with the properties and hazards of this compound. When operating, protective equipment such as protective gloves, glasses, masks, etc. should be prepared to protect their own safety. In the event of an unexpected situation such as leakage, it can be dealt with quickly according to the established emergency plan to minimize the harm. In this way, 4-bromo-2-fluoro-1-methanesulfonylbenzene is kept safe during storage and transportation.