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4-Bromo-2-Fluoro-1-Isopropoxybenzene

4-Bromo-2-Fluoro-1-Isopropoxybenzene

Hongda Chemical

Specifications

HS Code

180398

Chemical Formula C9H10BrFO
Molecular Weight 233.08
Appearance Typically a colorless to light - yellow liquid
Boiling Point Around 220 - 230 °C (estimated, actual may vary)
Density Approximately 1.45 - 1.55 g/cm³ (estimated)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, toluene
Flash Point Caution, flammable, flash point estimated around 90 - 100 °C
Vapor Pressure Low at room temperature

As an accredited 4-Bromo-2-Fluoro-1-Isopropoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 g of 4 - bromo - 2 - fluoro - 1 - isopropoxybenzene packaged in a sealed glass bottle.
Storage 4 - bromo - 2 - fluoro - 1 - isopropoxybenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent evaporation and contamination. Due to its potential reactivity, ensure it is separated from incompatible substances to avoid dangerous reactions.
Shipping 4 - bromo - 2 - fluoro - 1 - isopropoxybenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict chemical shipping regulations, ensuring proper handling to prevent spills and exposure during transit.
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4-Bromo-2-Fluoro-1-Isopropoxybenzene 4-Bromo-2-Fluoro-1-Isopropoxybenzene
General Information
Historical Development
4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene is an organic compound. It originated from the research of many sages. In the past, organic chemistry was flourishing, and many scholars were dedicated to the exploration of new things. In the field of halogenated aromatics, if you want to obtain products with special properties, you will pay attention to this compound.
At the beginning, the synthesis method was still simple and difficult to refine, and the yield was not good. However, after years of research, you have improved your skills. Or change the conditions of the reaction, or choose more reagents, and gradually improve the synthesis method. In today's world, 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene has its uses in medicine, materials, and other industries. This is the result of the diligent research of chemists of all generations, which has made it prosperous in this world since the beginning, adding brilliance to the development of chemistry.
Product Overview
Today there is a substance called 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene. This is an organic compound with a specific molecular structure. Looking at the formula, bromine (Bromo) and fluorine (Fluoro) atoms are attached to the benzene ring, and are connected by isopropoxy (Isopropoxy).
This substance has unique properties. Due to the halogen atoms of bromine and fluorine, it has certain electronegativity, which affects the polarity and reactivity of the molecule. The existence of isopropoxygen also plays a role in its physical and chemical properties. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique structure, it can participate in a variety of reactions, such as nucleophilic substitution, coupling reactions, etc., assisting chemists in creating a variety of novel organic molecules, which are potentially useful in many fields such as medicine and materials, and are expected to contribute to related research and industrial development.
Physical & Chemical Properties
4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene is an organic compound. Its physical and chemical properties are unique and related to many practical applications. From the perspective of physical properties, at room temperature and pressure, this substance may be in a liquid state, with a specific boiling point and melting point. The boiling point determines the temperature at which it converts to a gaseous state when heated, and the melting point is related to the transition between solid and liquid states. Its density is also an important parameter, reflecting the mass of a substance in a unit volume.
In terms of chemical properties, due to the presence of benzene rings, it has aromatic properties and can undergo electrophilic substitution reactions. The substituents of bromine, fluorine and isopropoxy give it unique activity. Bromine atoms are relatively active and can be replaced by other groups under certain conditions; fluorine atoms have large electronegativity, which affects the distribution of molecular electron clouds; isopropoxy groups can participate in some characteristic reactions of ethers. The physical and chemical properties of this compound lay the foundation for its application in organic synthesis and other fields.
Technical Specifications & Labeling
Today there is a product called 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene. The technical specifications and identification (product parameters) of this product should be studied in detail.
Looking at this substance, the preparation method must follow specific rules. The choice of raw materials must be pure and the proportion is appropriate to get the best effect. When reacting, various variables such as temperature and pressure need to be precisely controlled. If the heat is too high, the product may be mutated; if the heat is not enough, the reaction is incomplete and the quality is not pure.
As for the logo, when the name is clearly stated, the book "4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene" is visible to people at a glance. Remember its key parameters, such as molecular weight, melting point, boiling point, to help users understand its properties. On the packaging, there should also be a warning, if this thing has any dangerous characteristics, you should not be careless. In this way, the technical specifications and labels (product parameters) should be combined.
Preparation Method
4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene is an important organic compound. The raw materials and production process are crucial for the preparation of this compound.
In the selection of raw materials, when the benzene series compounds containing bromine and fluorine are used as the starting materials, and the isopropoxylation reagent is required. The purity and quality of these two are related to the purity and yield of the product.
In the production process, the reaction steps are as follows: First, the benzene series raw materials containing bromine and fluorine are mixed in a specific reaction vessel with a suitable catalyst to create a specific reaction environment. Temperature and pressure need to be precisely controlled. Then, slowly add the isopropoxylation reagent. This process should pay close attention to the reaction process to prevent side reactions. After the reaction is completed, it is separated and purified to obtain high-purity 4-Bromo-2-Fluoro-1-Isopropoxybenzene.
In this preparation process, a complete monitoring mechanism should be established to analyze and test the products at each step to ensure that they meet quality standards. In this way, the ideal 4-Bromo-2-Fluoro-1-Isopropoxybenzene product can be obtained.
Chemical Reactions & Modifications
4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene is an important compound in organic synthesis. In chemical reactions, phenols and halogenated hydrocarbons are commonly synthesized by Williamson ether. In this reaction, phenolic hydroxyl groups form phenoxy anions under basic conditions, which act as nucleophiles to attack the carbon-halogen bonds of halogenated hydrocarbons and undergo nucleophilic substitution reactions to generate the target product.
However, there is room for improvement in this reaction. First, the bases used in traditional methods may require harsh reaction conditions and have many side reactions. You can try to use milder bases or optimize the amount of bases to improve the reaction selectivity. Second, the activity of halogenated hydrocarbons has a great influence on the reaction. It can be considered to modify the structure of halogenated hydrocarbons to enhance their activity, make the reaction easier, shorten the reaction time and increase the yield. In this way, through the optimization of reaction conditions and reactants, it is expected to improve the synthesis of 4-Bromo-2-Fluoro-1-Isopropoxybenzene, and improve its preparation efficiency and quality.
Synonyms & Product Names
Today there is a product called 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene. This product is very important in my chemical research.
Looking at its name, we can know the characteristics of its chemical structure. "Bromo" is bromine; "Fluoro" is fluorine; "Isopropoxy" is isopropoxy, which is a key component of it.
As for its synonyms, although there is no widely known name, it is in the industry or has another name for its structure. The trade name will not be named until after marketing activities.
Our chemical researchers are committed to exploring the characteristics and uses of this product. It may have unique effects in the fields of organic synthesis. It is hoped that in the future, appropriate synonyms and trade names can be found for it, so that it can be better known in the industry, play a greater role, and promote the progress of chemical research and application.
Safety & Operational Standards
4 - Bromo - 2 - Fluoro - 1 - Safety and Operation Specifications of Isopropoxybenzene
Husband 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene is also a chemical product. To study its safety and operation, it is necessary to check the general elements.
First word safety. This thing may have chemical activity. If you pick it up, you should be careful. If it is too hard to be irritated, it is recommended to prevent clothing, such as chemical-resistant sleeves and gloves, from being stained with the skin. If you are not careful, wash it with a lot of water quickly, and you still don't feel it. If you are in a hurry, you should be careful.
In case of eye contact, there is also a risk of damage. The operation method must be worn in the eyes. If you are not careful about entering the eyes, immediately wash the mixture with water.
Furthermore, its smell or pungent, and it is harmful to inhalation. Therefore, the operation should be carried out in a good way, or placed in a row to prevent it from evaporating and accumulating, inhaling, causing respiratory failure or other diseases.
Until the operation is complete. Before use, the phase of the mixture is clear, and its nature and danger are clear. When the amount is high, use a fine measuring tool and take it according to the required amount. Do not lack it. Mix it, add it slowly, and do not mix it, to prevent the reaction from being strong.
The method of survival cannot be ignored. It should be stored in the oil, dry air, avoid fire, avoid oil, and divide the oil into the original oil to prevent accidental reaction.
Therefore, those who operate 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene must keep the safe operation to ensure their own safety and the safety of the environment.
Application Area
4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene is a unique chemical compound. The application field of Guanfus compound is quite considerable. In the field of medicinal chemistry, it may be used as a key intermediate to help create new specific drugs. Due to its unique molecular structure, it can be matched with specific targets in organisms, and is expected to emerge in the field of disease treatment, such as anti-tumor and anti-virus.
In the field of materials science, this compound may contribute to the research and development of new functional materials. With its bromine, fluorine and other elements, it may endow materials with unique properties such as excellent photoelectric properties and chemical stability, and then be applied to the preparation of advanced materials such as organic Light Emitting Diodes and sensors. In short, 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene has great potential in the application fields of medicine and materials, which needs to be deeply explored and excavated by us.
Research & Development
I am committed to the research and development of 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene. At the beginning, I explored its synthesis path, and thought hard about the selection of raw materials and the order of steps. I have tried all kinds of things, or because the conditions are not suitable, or because the reagents are poor, I have been frustrated many times. However, I am not discouraged, and repeatedly study the classics and seek advice from the Fang family.
Finally, I have obtained an exquisite method. With a certain raw material, after a specific reaction, I can obtain this product. Its purity and yield can be seen. Looking at this achievement and thinking about its application, it can be used in the fields of medicine and materials. However, the road ahead is still long, and it is necessary to study the performance in detail and expand the use. I will make unremitting efforts to make greater progress in the research and development of this object, and to contribute to the academic community and the industry, in recognition of the value of scientific research.
Toxicity Research
Recently, the toxicological analysis of 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene was carried out in detail. The structure of this substance is unique, and it contains bromine, fluorine and isopropoxybenzene, which may cause special toxicological effects.
After various experiments, its effect on the organism was observed. When mice were fed with food containing this substance, the behavior and physiology of the mice changed abnormally for several weeks. Their activities gradually slowed down, the amount of food they ate also decreased, and the organs also showed signs of damage. The color and texture of the liver were abnormal. From the perspective of slices, the structure of liver cells was disordered, or the substance interfered with cell metabolism.
It was also tested by plants. Adding an appropriate amount of this substance to the culture medium caused plant growth to be inhibited, leaf color to turn yellow, and root system to be stunted. This shows that 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene is significantly toxic and is harmful to the growth and metabolism of organisms. Follow-up application must be cautious, and protective measures must be studied in detail to avoid ecological disasters and endangering life.
Future Prospects
I have dedicated myself to the chemical substance 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene. Looking at the present, although there is a certain amount of research, there are still many areas to be explored in the future.
In the synthesis method, we hope to find a simpler, more efficient and environmentally friendly way. The consumption of raw materials is reduced, the yield is increased, and the impact on the ring is minimized. In this way, it is in line with the trend of future chemical industry.
The domain of its application is also expected to be expanded. Or in the field of medicine, it can become the key ingredient of new medicines, adding new power to the treatment of diseases; or in the field of materials, giving materials unique properties, such as better electrical conductivity, heat resistance, etc., to meet diverse needs.
I am convinced that with time and unremitting research, 4 - Bromo - 2 - Fluoro - 1 - Isopropoxybenzene will be able to shine in the future and make great contributions to the progress of mankind.
Where to Buy 4-Bromo-2-Fluoro-1-Isopropoxybenzene in China?
As a trusted 4-Bromo-2-Fluoro-1-Isopropoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Bromo-2-Fluoro-1-Isopropoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Bromo-2-Fluoro-1-Isopropoxybenzene?
4-Bromo-2-fluoro-1-isopropoxybenzene is also an organic compound. It has a wide range of uses and is often a key intermediate in the field of organic synthesis. Due to its unique structure, the presence of bromine, fluorine and isopropoxy gives it special reactivity and selectivity.
First, in pharmaceutical chemistry, it can be introduced into the molecular structure of a drug through a series of reactions. During drug development, this compound can be linked to other active fragments through nucleophilic substitution, coupling and other reactions to construct new compounds with specific pharmacological activities. For example, by palladium-catalyzed coupling reactions with nitrogen-containing heterocycles, potential drug molecules with high affinity and activity to specific disease targets can be prepared.
Second, in the field of materials science, it can be used to prepare functional materials. Due to its high electronegativity of fluorine atoms, it can enhance the stability and weather resistance of materials; bromine atoms can participate in subsequent polymerization reactions or modification reactions, so that materials have unique electrical and optical properties. For example, in the synthesis of organic optoelectronic materials, this can be used as a raw material, or organic semiconductor materials with high charge transport properties and good photostability can be synthesized.
Third, in the field of fine chemical manufacturing, 4-bromo-2-fluoro-1-isopropoxybenzene can be used as an important starting material for the synthesis of fine chemicals such as special fragrances and pesticide synergists. Through chemical transformation, fine chemicals with diverse structures can be derived to meet the specific needs of different industries.
In short, 4-bromo-2-fluoro-1-isopropoxybenzene, with its unique chemical structure, plays an important role in many fields such as organic synthesis, medicinal chemistry, materials science and fine chemical manufacturing, and has broad application prospects and research value.
What are the physical properties of 4-Bromo-2-Fluoro-1-Isopropoxybenzene?
4-Bromo-2-fluoro-1-isopropoxybenzene is one of the organic compounds. Its physical properties are quite inscrutable.
Looking at its properties, under normal temperature and pressure, it is usually a colorless to light yellow liquid. In this state, the fluidity is quite good. In the container, it can flow with the heart, like the water of a stream, which is smooth and natural.
When it comes to the boiling point, it is about within a certain temperature range. The boiling point is the critical temperature at which a substance changes from a liquid state to a gaseous state. At this temperature, the energy of the molecules in the liquid is enough to break free from the attractive forces between each other and escape into a gaseous state. The boiling point of 4-bromo-2-fluoro-1-isopropoxybenzene makes it possible to achieve phase transformation under certain conditions.
In terms of melting point, there are also specific values. The melting point is the temperature limit for the transformation of solid substances into liquid states. Below the melting point, it is in a solid state, and the molecules are arranged in a regular and orderly manner, just like a strict army array; when it reaches the melting point, the molecules gain more energy, and the arrangement begins to be chaotic, and then they turn into a liquid state.
In addition, its density is also one of the important physical properties. The density is also the mass of the substance per unit volume. The density of 4-bromo-2-fluoro-1-isopropoxybenzene makes it exhibit specific floating and sinking characteristics when mixed or contacted with other substances.
In terms of solubility, this compound often has a certain solubility in organic solvents, such as some common alcohols and ether solvents. It can interact with solvent molecules and disperse them uniformly. In water, its solubility is relatively limited, because the polarity of water and the polarity of the compound are quite different, making it difficult for the two to blend, just like the barrier between oil and water.
In addition, its volatility is also worthy of attention. Although it is not a highly volatile substance, under appropriate conditions, molecules can also escape from the liquid surface and disperse in the surrounding space, like a faint fragrance, slowly diffusing.
In summary, the physical properties of 4-bromo-2-fluoro-1-isopropoxybenzene are of great significance in chemical research and practical applications, laying the foundation for its subsequent operations and research.
What are 4-Bromo-2-Fluoro-1-Isopropoxybenzene synthesis methods?
The synthesis method of 4-bromo-2-fluoro-1-isopropoxybenzene can be discussed from the following numbers.
First, take 4-bromo-2-fluorophenol and react it with an isopropylation reagent. If an isopropyl halide (such as isopropyl bromide or isopropyl chloride) is used as an isopropylation reagent, in an alkaline environment, the oxygen atom of the phenolic hydroxyl group attacks the carbon atom of the isopropyl halide, and the halogen ion leaves, this is a nucleophilic substitution reaction. The basic reagent can be selected from potassium carbonate, sodium hydroxide, etc., in an appropriate solvent (such as N, N-dimethylformamide, acetone, etc.), heated and stirred to obtain the target product. The reaction conditions are relatively mild and the yield is considerable.
Second, halogenated benzene derivatives are used as starting materials. If there is a suitable 4-halogen-2-fluoro-1 - (halogenated isopropoxy) benzene, it can be cross-coupled by metal catalysis. For example, a palladium-catalyzed system, such as tetra (triphenylphosphine) palladium, etc., reacts with bromine or iodine-containing halogenated benzene derivatives in the presence of bases. This reaction can precisely construct carbon-oxygen bonds. Although the conditions are slightly complicated and require an anhydrous and anaerobic environment, it has many advantages for the synthesis of phenyl ethers with complex structures.
Third, start with the strategy of phenyl ring construction. The phenyl ring structure containing bromine, fluorine and isopropoxy can be constructed first. For example, through multi-step substitution reaction, bromine and fluorine atoms are introduced into the phenyl ring first, and then isopropoxy is introduced through nucleophilic substitution or other suitable reactions. Although this approach has many steps, it can flexibly design the reaction route and choose the appropriate method according to the availability of raw materials and reaction conditions, and can also achieve the synthesis of 4-bromo-2-fluoro-1-isopropoxy benzene.
4-Bromo-2-Fluoro-1-Isopropoxybenzene What are the precautions during storage and transportation?
For 4-bromo-2-fluoro-1-isopropoxybenzene, many matters must be paid attention to during storage and transportation.
Its properties may be unstable, and it may be dangerous in case of heat, open flames, oxidants, etc. Therefore, the storage place must be kept away from heat sources, fire sources, and do not co-store with oxidants. The warehouse should be cool, well ventilated, and the temperature and humidity should be appropriate to ensure its stability.
When transporting, caution must also be taken. The container used must be strong and sealed to prevent leakage. Load and unload the truck, and the action should be slow, so as not to cause collision or heavy pressure to cause damage to the container. Transportation vehicles should be equipped with corresponding fire and leakage emergency treatment equipment to avoid danger.
This substance may be toxic, irritating, or harmful to the human body and the environment. Operators and transporters should be in front of appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to prevent it from touching the skin and eyes. If there is a leak, quickly isolate the scene and restrict access. Emergency responders wear self-contained positive pressure respirators, anti-toxic clothing, small leaks, mixed with sand, dry lime, etc. Collect; if there is a large amount of leakage, build a dike or dig a pit to contain it, cover it with foam, reduce volatilization, and transfer it to a tanker or special collector for recycling or transportation to a waste treatment site for disposal.
During the storage and transportation of 4-bromo-2-fluoro-1-isopropoxybenzene, all relevant procedures should be strictly followed and handled with caution to ensure the safety of personnel, the environment is not damaged, and the material is properly stored and transported.
What is the market price of 4-Bromo-2-Fluoro-1-Isopropoxybenzene?
4-Bromo-2-fluoro-1-isopropoxybenzene, the price of this substance is difficult to determine in the market. The change in its price is related to various factors.
First, it is related to the production method. If it is obtained by a simple and low-cost method, its price is low; if the preparation method is complicated, rare raw materials are required, and a lot of manpower and material resources are consumed, the price will be high.
Second, the price of raw materials is also a major factor. If the raw materials required for the preparation of this compound are abundant, easy to obtain and low in price, the price of the finished product will also decrease; if the raw materials are scarce, the price is high and difficult to find, and the price of the finished product will increase.
Third, the supply and demand of the city determines the price. If the market has strong demand for this product, but the supply is limited, and the supply is in short supply, the price will rise; on the contrary, if the demand is weak, the supply is excessive, and the supply exceeds the demand, the price will drop.
Fourth, the price varies depending on the manufacturer. Large factories may have advantages due to their scale, sophisticated technology, or controllable cost; small factories may have higher prices due to higher costs.
As for the exact inter-market price, it is difficult to determine. To know the details, you should consult chemical product suppliers, or check the recent quotations of chemical raw material trading platforms to get a relatively accurate price.