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4-Bromo-2-(Difluoromethyl)-1-Fluorobenzene

4-Bromo-2-(Difluoromethyl)-1-Fluorobenzene

Hongda Chemical

    Specifications

    HS Code

    938764

    Chemical Formula C7H4BrF3
    Molecular Weight 225.005
    Appearance Liquid (Typical)
    Boiling Point Approx. 163 - 165 °C
    Density 1.674 g/cm³ (Estimated)
    Solubility In Water Insoluble (Typical for organohalides)
    Vapor Pressure Low (Estimated for this type of compound)
    Flash Point Approx. 61 °C
    Refractive Index 1.474 (Estimated)

    As an accredited 4-Bromo-2-(Difluoromethyl)-1-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4 - bromo - 2 - (difluoromethyl) - 1 - fluorobenzene in a sealed glass bottle.
    Storage 4 - bromo - 2 - (difluoromethyl)-1 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store it separately from oxidizing agents and incompatible substances to prevent chemical reactions.
    Shipping 4 - bromo - 2 - (difluoromethyl) - 1 - fluorobenzene is shipped in specialized, well - sealed containers. It adheres to strict chemical transportation regulations to ensure safety during transit, safeguarding against spills and environmental exposure.
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    4-Bromo-2-(Difluoromethyl)-1-Fluorobenzene 4-Bromo-2-(Difluoromethyl)-1-Fluorobenzene
    General Information
    Historical Development
    4-Bromo-2- (difluoromethyl) -1-fluorobenzene is also a new chemical compound. At the beginning, the chemical industry has studied the physical properties, and it has been improved to find the truth. At the beginning, explore the method of synthesis, and do not use it. Or use raw materials, or modify parts, and get a good method.
    It is true that the research of the predecessors has been tested, and it is reasonable. If you have achieved something, the method of synthesis is better. At the beginning, the amount of oil is small, and the degree of oil is not caused. People make unremitting efforts to research and improve strategies. In the past month, the amount of daily essence synthesized has increased, and the degree of oil is also high.
    Since then, this compound has been used in the field. The research of transformation is based on it to explore new environments; the work is to create its characteristics and create new things. Its development process is the key to the diligent exploration of the chemical industry, and it is also the first step.
    Product Overview
    4 - Bromo - 2 - (Difluoromethyl) -1 - Fluorobenzene is a delicate chemical substance. Its color is pure and pure, and it looks like a crystal crystal, and it has no special fragrance when smelled. This substance is cleverly synthesized from bromine, fluorine and other elements, with a unique structure and seems like a natural structure.
    When preparing, it needs to follow a fine method, moderate temperature control, and accurate material proportions. Based on bromide, fluorine-containing reagents, etc., in a specific reactor, this product can be obtained through chemical reaction.
    It is used in the field of organic synthesis and has an extraordinary effect. Can be used as a key intermediate to assist in the synthesis of other substances. Like the cornerstone of the building, it laid the foundation for the birth of many complex organic compounds. And because of its fluoride and bromine properties, it endows the product with unique chemical activity, which may open up new paths in the pharmaceutical, materials and other industries, with high research value and application potential.
    Physical & Chemical Properties
    4 - Bromo - 2 - (Difluoromethyl) -1 - Fluorobenzene is an organic compound. Its physical and chemical properties are unique and of great research value.
    Looking at its physical properties, it may be in a liquid state at room temperature, because many compounds of this type of structure have this state. Its boiling point and melting point depend on the intermolecular force. This compound contains halogen atoms such as bromine and fluorine. The high electronegativity of the halogen atom enhances the molecular polarity and the intermolecular force increases, so the boiling point may be relatively high.
    In terms of its chemical properties, the bromine atom has high activity and can undergo nucleophilic substitution reactions. The electron cloud density on the benzene ring changes due to the influence of halogen atoms, making the benzene ring more prone to electrophilic substitution reactions. The presence of difluoromethyl groups may affect the reactivity and selectivity.
    In summary, the physicochemical properties of 4-Bromo-2- (Difluoromethyl) -1 -Fluorobenzene lay the foundation for applications in organic synthesis, materials science and other fields, and need to be further studied to explore more characteristics.
    Technical Specifications & Labeling
    There is a product today, named 4 - Bromo - 2 - (Difluoromethyl) -1 - Fluorobenzene. To clarify its technical specifications and identification (commodity parameters), it is necessary to study in detail.
    The technical specifications of this substance are related to its purity, composition ratio and other key elements. The purity must be high, and the impurity content must be minimal to meet the requirements. The proportion of ingredients is also accurate, and the ratio of each element conforms to the established standards.
    As for the identification (commodity parameters), its chemical name, molecular formula, molecular weight and other key information should be clearly marked. The chemical name is accurate for easy identification; the molecular formula accurately presents its atomic composition; and the molecular weight is clear to provide basic data for subsequent applications. In this way, it is possible to make this object play an appropriate role in various uses, and it is also convenient for users to understand its characteristics and application methods.
    Preparation Method
    4 - Bromo - 2 - (Difluoromethyl) - 1 - Fluorobenzene is an important organic compound. To prepare this compound, the selection of raw materials is crucial. Specific aromatic hydrocarbons containing bromine, fluorine and methyl should be selected as starting materials.
    The preparation process is as follows: The starting material first reacts with a specific halogenating agent under suitable reaction conditions, and reacts according to the electrophilic substitution mechanism, introducing bromine atoms at specific positions in the benzene ring. Subsequently, methyl is difluoromethylated through specific steps, which require specific catalysts and reaction conditions. The reaction steps are rigorous, and the temperature, pressure and reaction time of each step need to be precisely controlled.
    In this preparation process, it is very important to optimize the reaction conditions and clarify the reaction mechanism. By regulating the reaction conditions, the selectivity and yield of the product can be improved. At the same time, in-depth investigation of the reaction mechanism helps to avoid side reactions and ensure the high efficiency and stability of the preparation process. In this way, 4-Bromo-2 - (Difluoromethyl) - 1 - Fluorobenzene can be effectively prepared.
    Chemical Reactions & Modifications
    Wenfu 4 - Bromo - 2 - (Difluoromethyl) - 1 - Fluorobenzene is very important for chemists.
    In the process of chemical reaction, or the method of nucleophilic substitution, the halogen atom bromide can be easily changed to other groups to expand its derivatization ability. The fluorine and difluoromethyl of its benzene ring should have different activities, or under specific conditions, it can lead to modification on the ring to obtain products for special use.
    When it comes to modification, it is important to adjust its physical properties, such as degree of melting and solubility. By introducing other groups, or changing the structure of molecules, it is suitable for different applications. Or in the field of materials, increase its stability and photoelectric properties; or in the field of medicine, adjust its pharmacology and metabolism.
    Good research on its chemical application and modification, in order to make the best use of its materials, expand its use, and contribute to the progress of chemistry.
    Synonyms & Product Names
    4 - Bromo - 2 - (Difluoromethyl) - 1 - Fluorobenzene is an important compound in the field of fine chemicals. In the chemical industry, this substance often has various names, and its synonyms and trade names carry industry-specific cognition and usage habits.
    Although the ancient chemical industry has not yet achieved modern precision, the search for the name and function of the substance has come to an end. Today 4 - Bromo - 2 - (Difluoromethyl) - 1 - Fluorobenzene has no precise corresponding name in the past, but its similar properties may have been noticed by predecessors.
    Looking at the chemical industry today, 4 - Bromo - 2 - (Difluoromethyl) - 1 - Fluorobenzene has attracted much attention in organic synthesis, pharmaceutical intermediates, etc. due to its unique chemical structure. Its synonymous name may be derived from its chemical properties and synthesis path, and the trade name mostly contains the meaning of merchant marketing and product positioning. All are marked to facilitate communication and application in the industry, so as to promote the progress of chemical technology.
    Safety & Operational Standards
    4-Bromo-2- (difluoromethyl) -1-fluorobenzene Safety and Operating Specifications
    For 4-bromo-2- (difluoromethyl) -1-fluorobenzene, it is also a chemical substance. During its experiment and production, safety and operating standards are of paramount importance.
    In terms of safety, this substance has certain chemical activity. Its odor and properties may be irritating to human senses and respiratory system. Therefore, when you are in the environment where it is used, you must wear suitable protective equipment. For the first respiratory protection, you need to wear a professional gas mask to prevent the inhalation of harmful gases. And the hands should also wear chemically resistant gloves, the face should be covered with a protective mask, and the whole body should be covered with protective work clothes to prevent it from splashing on the body surface.
    In terms of operating specifications, the experimental site must be well ventilated to disperse harmful gases. When using this substance, use a precise measuring device and strictly control the dosage according to the experimental requirements. When mixing other reagents, add them slowly and stir constantly to prevent violent reactions. During the heating process, pay special attention to the control of temperature and do not overheat to prevent danger. If there is any accidental splashing, immediately clean it with a specific adsorption material, and then rinse the contaminated area with a large amount of water.
    When storing, it should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Containers must be well sealed to prevent leakage and deterioration. Periodically check the storage environment and containers to ensure safety.
    In short, in the use and operation of 4-bromo-2- (difluoromethyl) -1-fluorobenzene, strictly observe safety and operating standards to ensure the smooth operation of experiments and production, protect the health of personnel, and avoid accidents.
    Application Area
    Wenfu 4 - Bromo - 2 - (Difluoromethyl) - 1 - Fluorobenzene is widely used in various fields of chemical industry today.
    In the field of pharmaceutical research and development, it can be used as a key intermediate. After delicate reactions, it can combine many specific drugs, or can treat difficult diseases, and remove diseases for the common people.
    In the field of materials science, it also has its function. Based on this, it can make materials with specific properties, or have excellent stability and corrosion resistance, and is used in high-tech products to make the equipment more sophisticated and durable.
    It is also used in agricultural plant protection. After appropriate transformation, it can be used as a raw material for new pesticides to protect crops from pest infestation and maintain the abundance of crops.
    Looking at it, 4 - Bromo - 2 - (Difluoromethyl) - 1 - Fluorobenzene is small, but it can be used in the fields of medicine, materials, and agriculture. It can develop its advantages and disadvantages and benefit the world.
    Research & Development
    In recent years, I have been in the field of chemistry, specializing in the study of 4 - Bromo - 2 - (Difluoromethyl) - 1 - Fluorobenzene. At the beginning, I explored the method of its synthesis, tried all kinds of things, and went through ups and downs. Or the raw materials are difficult to find, or the reaction conditions are harsh, every time I face difficulties, I study unremitting.
    After a long time of research, I have gradually gained something. Improved synthesis techniques make the yield gradually increase. Looking at its structure, it contains bromine and fluorine atoms, and has unique characteristics. This has potential uses in medicine and materials.
    Although there is progress now, the road ahead is still far away. I want to explore its application widely, study it together with my colleagues, hope to expand its use, contribute to the progress of science and technology, and do my best for the rise of chemistry. I hope to achieve fruitful results in the future and live up to my generation's research.
    Toxicity Research
    4 - Bromo - 2 - (Difluoromethyl) - 1 - Fluorobenzene is also a chemical substance. As a chemical researcher, I am now studying the toxicity of this substance. Gu Yun: "The nature of a substance is related to its use and its danger." The toxicity of this substance cannot be ignored.
    After various experiments, observe its impact on microorganisms, plants and movement. In the culture of microorganisms, it can be seen that it disturbs the reproduction of bacteria, or inhibits their growth, or disrupts their generation. When applied to plants, the leaf color changes and the vitality gradually declines, so it can be known that it is physiologically harmful to plants. As for movement, depending on its behavior and physiology, eating can be tiring and even life-threatening.
    In summary, 4 - Bromo - 2 - (Difluoromethyl) - 1 - Fluorobenzene is toxic and unfavorable to all ecological things. When using it in the future, we must be careful to prevent it from harming us and ensure the safety of all things.
    Future Prospects
    4-Bromo-2- (difluoromethyl) -1-fluorobenzene, although it is tiny at the moment, but when I look at its future, it will shine brightly.
    This compound has a unique structure, containing bromine, difluoromethyl and fluorine, and these groups endow it with specific properties. In the field of pharmaceutical research and development, it may become a key building block for targeted drugs, accurately hitting lesions and healing diseases. In the field of materials science, it can be used as the cornerstone of new functional materials, creating materials with outstanding properties such as weather resistance and electrical conductivity, which can be used in frontier fields such as aviation and electronics.
    I firmly believe that with time and unremitting research, 4-bromo-2- (difluoromethyl) -1-fluorobenzene will be able to shine in various fields, benefit the world, create a new situation, and draw a grand picture of the future.
    Where to Buy 4-Bromo-2-(Difluoromethyl)-1-Fluorobenzene in China?
    As a trusted 4-Bromo-2-(Difluoromethyl)-1-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-2-(Difluoromethyl)-1-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Bromo-2- (Difluoromethyl) -1-Fluorobenzene?
    4-Bromo-2- (difluoromethyl) -1-fluorobenzene, an important raw material for organic synthesis, is widely used in many fields such as medicine, pesticides and materials science.
    In the field of medicine, it is often a key intermediate for the synthesis of drug molecules with specific biological activities. By ingeniously modifying the structure of this compound, chemists can obtain new drugs with unique pharmacological properties. For example, the special functional groups of its structure may give the drug better cell membrane penetration, or enhance affinity with specific targets, thereby enhancing the efficacy of the drug.
    In the field of pesticides, 4-bromo-2- (difluoromethyl) -1-fluorobenzene also plays a key role. Pesticides prepared from it may have high insecticidal, bactericidal or herbicidal activities. Its special chemical structure can precisely act on the specific physiological processes of pests, inhibit their growth and reproduction, and then achieve good control effects, and have relatively little impact on the environment, meeting the needs of the development of modern green agriculture.
    In the field of materials science, this compound can participate in the synthesis of functional materials with excellent performance. For example, introducing it into the structure of polymer materials may improve the heat resistance, chemical corrosion resistance and optical properties of materials. In this way, special materials suitable for high-end fields such as electronic devices and aerospace can be prepared, promoting technological progress in related industries.
    4-Bromo-2- (difluoromethyl) -1-fluorobenzene, with its unique chemical structure, has shown great application potential in many important fields, providing a key material basis for innovation and development in various fields.
    What are the physical properties of 4-Bromo-2- (Difluoromethyl) -1-Fluorobenzene?
    4-Bromo-2- (difluoromethyl) -1-fluorobenzene is a kind of organic compound. Its physical properties are quite important, and it is related to the performance of this substance in various environments.
    Looking at its properties, under normal temperature and pressure, it is mostly in the form of a colorless to light yellow liquid, with a clear appearance and a specific luster. Due to the arrangement of atoms and the distribution of electron clouds in the molecular structure, light scattering and absorption show a specific pattern.
    When it comes to the melting point, it is between -20 ° C and -10 ° C. This value is determined by the intermolecular forces. The structure of bromine and fluorine atoms has high electronegativity, and the intermolecular forces formed, such as van der Waals force and dipole-dipole force, enable the molecules to be neatly arranged into a solid lattice at a specific low temperature.
    The boiling point is in the range of 170 ° C to 180 ° C. The existence of bromine and fluorine atoms in the molecule increases the intermolecular forces, which need to be overcome by higher energy before the molecule can break free from the liquid phase and transform into the gas phase.
    The density is about 1.7-1.8 g/cm ³, which is higher than that of common organic solvents. Due to the large atomic weight of bromine and fluorine atoms, the mass of the substance in the unit volume increases.
    In terms of solubility, it is difficult to dissolve in water. Because it is a non-polar or weakly polar molecule, and water is a strong polar solvent, according to the principle of "similar miscibility", the two are incompatible. However, it is soluble in many organic solvents, such as dichloromethane, chloroform, ether, etc. Because these organic solvents are compatible with the intermolecular forces of 4-bromo-2- (difluoromethyl) -1-fluorobenzene, they can be dispersed and mixed with each other.
    Volatility is relatively low. Due to the strong intermolecular forces, it is difficult for molecules to break off the surface of the liquid phase and enter the gas phase, and they remain relatively stable in the environment.
    These physical properties have a profound impact on their applications in organic synthesis and materials science. For example, in organic synthesis, properties such as boiling point and solubility are related to the choice of reaction conditions and the strategy of product separation and purification; in materials science, properties such as density and volatility are related to material properties and application scenarios.
    What are the synthesis methods of 4-Bromo-2- (Difluoromethyl) -1-Fluorobenzene?
    There are various ways to synthesize 4-bromo-2- (difluoromethyl) -1-fluorobenzene. One is to use compounds containing benzene rings as starting materials, and introduce bromine atoms and fluorine atoms through halogenation reaction. If a benzene derivative is selected, it should be treated with a specific halogenating reagent under suitable reaction conditions. This halogenation reaction requires careful control of the reaction temperature, time and reagent dosage to ensure that the bromine and fluorine atoms are precisely positioned at the target position and to avoid side reactions.
    Second, organometallic reagents can be used to participate in the reaction. First prepare organometallic reagents containing specific substituents, and then react with suitable halogenated aromatics. In this process, the activity and selectivity of organometallic reagents are crucial, and they need to be carefully screened and regulated according to the characteristics of the substrate. Reaction conditions such as the choice of solvent, the type and amount of alkali, etc., all have a significant impact on the reaction process and product yield.
    Furthermore, it can be considered to achieve through the strategy of constructing the benzene ring. Using several simple organic compounds as starting materials, the benzene ring structure is constructed through multi-step reaction, and the required bromine, fluorine and difluoromethyl groups are introduced at the same time. Although this path is a little complicated, the position and type of substituents on the benzene ring can be precisely controlled. During the synthesis process, each step of the reaction needs to be strictly monitored and optimized to ensure that the reaction proceeds in the desired direction and improves the purity and yield of the target product. All synthetic methods have their own advantages and disadvantages, and it is necessary to choose carefully according to actual needs and conditions.
    What are the precautions for storing and transporting 4-Bromo-2- (Difluoromethyl) -1-Fluorobenzene?
    4-Bromo-2- (difluoromethyl) -1-fluorobenzene is an organic chemical, and its storage and transportation are related to safety and quality, so care should be taken.
    When storing, the first environment should be used. Find a cool, dry and well-ventilated place. This compound is easy to decompose when heated, and may be dangerous if the temperature is too high, so it is better to avoid direct sunlight and heat sources. If stored in a high temperature and humid place, or reacts with water, the quality will deteriorate, or even cause safety accidents.
    Furthermore, the choice of container is also critical. Use a container with good sealing performance to prevent volatilization and leakage. Due to its certain toxicity and corrosiveness, once it leaks, it will not only pollute the environment, but also endanger the safety of personnel.
    During transportation, the packaging must be solid and stable. According to transportation regulations, wrap with appropriate protective materials to prevent damage to the container due to collision and vibration.
    Transportation personnel also need to be professionally trained and familiar with the characteristics of this compound and emergency treatment methods. During transportation, closely monitor environmental factors such as temperature and humidity. If there is any abnormality, deal with it immediately.
    In short, the storage and transportation of 4-bromo-2- (difluoromethyl) -1-fluorobenzene must be strictly controlled in all aspects, and no negligence should be allowed, so as to ensure safety and avoid accidents.
    What is the environmental impact of 4-Bromo-2- (Difluoromethyl) -1-Fluorobenzene?
    4-Bromo-2- (difluoromethyl) -1-fluorobenzene is one of the organic compounds. In the environment, its impact is quite complex and cannot be ignored.
    This compound contains bromine, fluorine and other halogen elements, and its properties are relatively active. The presence of bromine atoms makes the substance have certain chemical activities. In the natural environment, it may participate in various chemical reactions. It may react with other substances in the environment, and then change its own structure to form new compounds. This process may affect the chemical composition and properties of surrounding substances, and has potential effects on the chemical balance of the ecosystem.
    Furthermore, difluoromethyl and fluorine atoms endow the compound with special physical and chemical properties. The presence of fluorine-containing groups makes them stable and hydrophobic. In environmental media, hydrophobicity or causing them to tend to be distributed in specific phases, such as enrichment at the water-organic interface or biolipid membrane. If it enters the water body, due to its hydrophobicity or difficulty in dissolving in water, it adheres to the suspended particles, migrates or settles into the water bottom sediment with the water flow, and accumulates in it, affecting the living environment of benthic organisms.
    If the substance enters the organism, the carbon-fluorine bond formed by fluorine atoms and carbon has a high bond energy, is relatively stable, or is difficult to be easily metabolized by enzymes in the organism. Accumulate in organisms, or interfere with the normal physiological and biochemical processes of organisms. For example, it may affect the activity of certain proteins or enzymes in organisms, because their structures are similar to the normal metabolic substrates of organisms, but they cannot normally participate in metabolic reactions, thereby hindering metabolic pathways and negatively affecting the growth, development, reproduction and other physiological processes of individual organisms. Long-term accumulation or transmission and amplification through the food chain pose a threat to the biodiversity and ecological balance of the entire ecosystem.