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4-Bromo-2-(Bromomethyl)-1-Fluorobenzene

4-Bromo-2-(Bromomethyl)-1-Fluorobenzene

Hongda Chemical

    Specifications

    HS Code

    284097

    Chemical Formula C7H5Br2F
    Molecular Weight 269.92
    Appearance Solid (Typical)
    Solubility In Water Low (Expected due to non - polar nature)
    Stability Stable under normal conditions (but reactive due to bromo and bromomethyl groups)

    As an accredited 4-Bromo-2-(Bromomethyl)-1-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - bromo - 2 - (bromomethyl)-1 - fluorobenzene in a sealed chemical - grade bottle.
    Storage 4 - bromo - 2 - (bromomethyl)-1 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to prevent potential reactions.
    Shipping 4 - bromo - 2 - (bromomethyl)-1 - fluorobenzene is a chemical. Shipping should be in accordance with hazardous material regulations. It must be properly packaged to prevent leakage during transit to ensure safety.
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    4-Bromo-2-(Bromomethyl)-1-Fluorobenzene 4-Bromo-2-(Bromomethyl)-1-Fluorobenzene
    General Information
    Historical Development
    4 - Bromo - 2 - (Bromomethyl) - 1 - Fluorobenzene is an important compound in the field of organic synthesis. Looking back in the past, the development process of this compound is of great significance. In the early years, organic chemistry research was still in its infancy, and the properties and synthesis paths of many compounds were yet to be explored. At that time, chemical researchers were dedicated to developing new synthesis methods to prepare various organic compounds.
    With the passage of time, chemical theory and experimental technology have advanced. Researchers have gradually clarified the key to the synthesis of 4 - Bromo - 2 - (Bromomethyl) - 1 - Fluorobenzene through repeated experiments and theoretical derivation. From the initial simple idea to the fine experimental design, unremitting exploration has made the synthesis method gradually mature. Every step of progress has focused the efforts of researchers, laying the foundation for its wide application in organic synthesis and launching a new journey in chemical research.
    Product Overview
    Today there is a substance called 4 - Bromo - 2 - (Bromomethyl) - 1 - Fluorobenzene. Its shape is also substituted by bromine and fluorine, and its structure is exquisite. Bromine atoms, bromomethyl and fluorine atoms are arranged in order according to their positions on the benzene ring.
    This substance has unique properties. Due to the characteristics of bromine and fluorine, it is endowed with different chemical activities. The activity of bromine and the stability of fluorine are extraordinary for co-casting. In the field of organic synthesis, it can be a key intermediate, leading to the direction of reaction and forming new bonds. Or participating in nucleophilic substitution, or involving additive changes, all of which are possible due to its structure.
    Looking at its application, in pharmaceutical research and development, it may be the basis for the creation of new agents; in material science, it may also be the source for the creation of specific materials. On the road of chemistry, it is like a star piloting, guiding researchers to explore the unknown, open up new frontiers, contribute to the prosperity of chemistry, promote the progress of science and technology, and benefit the world.
    Physical & Chemical Properties
    4 - Bromo - 2 - (Bromomethyl) - 1 - Fluorobenzene is also an organic compound. Its physical and chemical properties are quite important to scholars. Looking at its physical properties, under room temperature, or in a solid state, with a certain melting point, the color state may be in the shape of a white crystal, and the texture may be a fine powder.
    In terms of its chemical properties, the existence of halogen atoms makes it highly active. Bromine and fluorine atoms give it unique reactivity. In the nucleophilic substitution reaction, halogen atoms are easily attacked by nucleophiles, resulting in the generation of substitution products. Bromine atoms on methyl groups are also different in reactivity due to the influence of ortho-fluorine atoms. It can react with many reagents, such as alcohols, amines, etc., to form various derivatives. The physicochemical properties of this compound provide many possibilities for organic synthesis, materials science and other fields, and are an indispensable part of chemical research.
    Technical Specifications & Labeling
    4 - Bromo - 2 - (Bromomethyl) -1 - Fluorobenzene is an important organic compound. Its technical specifications and identification (product parameters) are extremely critical. The appearance of this compound may be a colorless to light yellow liquid with a special odor. Its boiling point, melting point, density and other physical parameters are indispensable in production and application.
    In terms of identification, its chemical name and molecular formula should be clearly defined as C H Br ² F. In terms of technical specifications, the purity must reach a high standard and the impurity content should be strictly controlled. For example, the moisture content must not exceed a specific value to ensure product quality.
    During the production process, the reaction conditions, such as temperature, pressure and reaction time, need to be precisely controlled to ensure that the product meets the technical specifications. At the same time, each batch of products should be strictly labeled and parameter tested to ensure their quality and stability, and to meet the needs of various fields of application.
    Preparation Method
    To prepare 4-bromo-2- (bromomethyl) -1-fluorobenzene, the raw materials and production process, reaction steps and catalytic mechanism are very important. First, an appropriate amount of fluorobenzene is taken and reacted with a brominating agent. Under specific conditions, bromine atoms can replace hydrogen at a specific position in the benzene ring to obtain bromine-containing intermediates. This step requires precise temperature control and time control to make the reaction moderate.
    Then, the intermediate is reacted with reagents containing methyl and bromine sources under the action of a suitable catalyst. The catalyst can reduce the activation energy of the reaction, accelerate the introduction of methyl and bromine atoms, and generate the target product. After each step of the reaction, it needs to be separated and purified to remove impurities to obtain pure products. This preparation method focuses on accurate control of each link in order to obtain this product efficiently.
    Chemical Reactions & Modifications
    Taste the wonders of chemical industry, the changes are endless, and the new material is formed, which is related to the reaction and modification. In this sentence, 4 - Bromo - 2 - (Bromomethyl) - 1 - Fluorobenzene is a compound. The reaction path of this compound is quite elusive.
    If you want to change its properties, you often use chemical methods to adjust the reaction conditions, such as temperature, solvent, and catalyst. Temperature can promote the movement of molecules and speed up their reaction. Appropriate temperature can cause the bromo group to undergo nucleophilic substitution with bromo methyl, or with the fluorobenzene ring, in order to change its structure.
    Solvents are also critical, and the difference in polarity and non-polarity affects the rate and direction of the reaction. Polar solvents are conducive to ionic reactions, which can help nucleophiles approach substrates and increase reactivity.
    The design of the catalyst can lower the energy barrier of the reaction, so that the originally difficult reaction can occur smoothly. After various attempts, this compound may be able to acquire new characteristics, develop its functions in the fields of medicine and materials, and contribute to the progress of chemical industry.
    Synonyms & Product Names
    Today there is a thing called 4 - Bromo - 2 - (Bromomethyl) - 1 - Fluorobenzene. This is a chemical product, which is quite important in the industry. It also has many synonymous names and commodity names.
    The name of the synonym is covered by the principle of chemistry, and it is named from different angles. Or according to its structural characteristics, or according to its composition, various expressions are generated, but they all refer to the same thing.
    The name of the product is related to the operation of the market. Merchants give it a unique title for the convenience of promotion and sales. This product name can not only highlight the characteristics of the product, but also facilitate the identification and distinction of the industry.
    When we study chemistry, we should examine its synonymous names and commodity names in detail. Knowing its many terms can be accurate and not confused in academic exchanges, experimental operations and market trade. This is of great benefit to the progress of chemical research.
    Safety & Operational Standards
    4 - Bromo - 2 - (Bromomethyl) -1 - Fluorobenzene Safety and Operation Specifications
    Fu 4 - Bromo - 2 - (Bromomethyl) -1 - Fluorobenzene is an important compound in chemical research. During its research and use, safety and operation standards are of the utmost importance and cannot be ignored.
    #1. Storage Method
    This compound should be placed in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent accidents. Because of its certain chemical activity, it may react violently in case of heat or open flame, endangering safety. The storage place should also be separated from oxidizing agents, strong alkalis and other substances to avoid interaction and cause danger.
    #2. Rules of Operation
    When operating, the experimenter must wear protective clothing, protective gloves and goggles. This compound may irritate the skin and eyes, and if it is not careful, it will cause injury. The operation should be carried out in a fume hood to prevent the escape of harmful gases and endanger the health of the experimenter. If you need to weigh this compound, the action should be steady and accurate to avoid spillage.
    #3. Emergency measures
    In case of accidental contact with the skin, rinse with plenty of water immediately, and then seek medical treatment. If it enters the eye, it is necessary to quickly rinse with flowing water or normal saline and seek medical assistance. In case of leakage, evacuate personnel immediately and cut off the fire source. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be built or dug for containment, and then properly disposed of.
    In short, during the research and operation of 4 - Bromo - 2 - (Bromomethyl) -1 - Fluorobenzene, safety should be the top priority and operating standards should be strictly adhered to to to prevent problems before they occur and ensure the smooth progress of the research work.
    Application Area
    4 - Bromo - 2 - (bromomethyl) -1 - fluorobenzene, the application field of this compound is very critical. In the field of organic synthesis, it can be used as an important intermediate. Due to the unique activity of bromine, fluorine atom and bromomethyl group in the molecule, many complex organic structures can be constructed through various chemical reactions. For example, in the coupling reaction of halogenated aromatics, it can interact with other compounds containing active groups to prepare new functional materials. In the field of drug development, it also has potential value. With specific functional groups, or molecules with specific pharmacological activities can be modified and synthesized, providing the possibility of creating novel drugs. And because of its structural properties, it may participate in the construction of key pharmacophore of drug molecules, which helps to improve drug efficacy and specificity. In short, this compound has broad application prospects in the fields of organic synthesis and drug development.
    Research & Development
    Today there is a product, named 4 - Bromo - 2 - (Bromomethyl) - 1 - Fluorobenzene. I am a chemical researcher, and I have been studying it for a long time.
    The study of this product is related to many aspects. Its structure is unique, and the arrangement of bromine, fluorine atoms and bromomethyl groups affects its chemical properties. To understand its properties, it is necessary to observe it experimentally and observe its reaction under different conditions.
    Study the method of its preparation, explore the optimal path, and hope to improve the yield and reduce its cost. At the same time, consider its impact on the environment, and strive for a green path.
    Looking forward to its development, it may be useful in the fields of medicine and materials. If we can make good use of its characteristics, we will be able to contribute to the progress of the industry, promote the development of chemical research, and achieve new opportunities.
    Toxicity Research
    Recently, Yu Yan 4 - Bromo - 2 - (Bromomethyl) - 1 - Fluorobenzene toxicity of this substance. It is an organic halide, containing bromine, fluorine and other halogen atoms.
    Experiments show that this compound has a significant effect on living organisms. In mice experiments, if exposed to this substance, their movements gradually slowed down and their eating also decreased. Anatomy shows that the organs are damaged to varying degrees, the liver is abnormal in color, and the kidney function also appears to decline.
    Investigate the reason, or because of its active halogen atoms, it is easy to replace with macromolecules in living organisms, resulting in damage to the structure and function of proteins, nucleic acids, etc.
    And this substance is difficult to degrade in the environment and is easy to accumulate. If the surrounding water bodies are contaminated by it, aquatic organisms are also implicated. Therefore, the study of the toxicity of this substance cannot be slack, and it is necessary to find proper protection and treatment methods to ensure the well-being of life and the environment.
    Future Prospects
    Guanfu 4 - Bromo - 2 - (Bromomethyl) - 1 - Fluorobenzene has great potential in the field of chemical industry. The future development is expected to emerge in the way of pharmaceutical synthesis. With its unique structure, it may become a key raw material for the creation of new drugs, helping to overcome difficult diseases and seek well-being for the world.
    In the field of materials science, there is also an opportunity for expansion. It may be possible to integrate new materials through ingenious processes, giving materials different properties, such as enhancing their stability, improving their electrical and thermal conductivity, and then promoting innovation in the field of materials.
    Furthermore, with the advancement of science and technology, the process of synthesizing this compound will continue to be optimized. Energy consumption may be greatly reduced, resulting in a purer product, which not only reduces costs but also benefits the environment. This is the future of 4 - Bromo - 2 - (Bromomethyl) - 1 - Fluorobenzene.
    Where to Buy 4-Bromo-2-(Bromomethyl)-1-Fluorobenzene in China?
    As a trusted 4-Bromo-2-(Bromomethyl)-1-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-2-(Bromomethyl)-1-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Bromo-2- (Bromomethyl) -1-Fluorobenzene?
    4-Bromo-2- (bromomethyl) -1-fluorobenzene is one of the organic compounds. Its main uses are quite extensive and are often found in the field of organic synthesis.
    In pharmaceutical chemistry, it is often used as a key intermediate. Drug developers can create new drug molecules with specific biological activities by modifying and modifying their chemical structures. For example, it can be combined with other compounds containing specific functional groups through a series of chemical reactions, and ingeniously designed to construct drugs that can precisely act on specific targets in the human body to achieve the purpose of treating diseases.
    In the field of materials science, it also has important uses. It may participate in the synthesis process of polymer materials and endow the materials with novel properties. By introducing it into the polymer structure, the solubility, thermal stability and optical properties of the material may be improved. For example, through specific polymerization reactions, materials with unique photoluminescence properties can be prepared, which may have broad application prospects in the manufacture of optoelectronic devices such as Light Emitting Diodes and optical sensors.
    In addition, in the field of fine chemicals, 4-bromo-2- (bromomethyl) -1-fluorobenzene can be used to prepare special organic reagents. These organic reagents can act as catalysts, ligands, etc. in organic synthesis reactions, helping to achieve more efficient and precise chemical reactions, resulting in the synthesis of many complex and unique fine chemicals, such as fragrances, dyes, and specialty coatings.
    What are the synthesis methods of 4-Bromo-2- (Bromomethyl) -1-Fluorobenzene?
    The synthesis of 4-bromo-2- (bromomethyl) -1-fluorobenzene is a key topic in the field of organic synthesis. There are many common ways to synthesize this compound.
    First, fluorobenzene derivatives can be initiated. First, bromine fluorobenzene with a specific halogenating reagent, such as bromine, under appropriate catalyst and reaction conditions, and introduce bromine atoms at specific positions in the benzene ring. After that, methyl is introduced through a suitable methylating reagent in a specific reaction environment, and further bromine atoms are introduced on the methyl by bromination, so that the target product can be obtained. This process requires precise control of reaction conditions, such as temperature, reaction time, and reagent dosage, in order to improve yield and selectivity.
    Second, it can also start from other functionalized benzene derivatives. For example, first introduce suitable substituents and gradually build the structure of the target molecule through a series of functional group conversion reactions. Through ingenious design of reaction routes, various organic reactions, such as nucleophilic substitution, elimination, and addition, are used to construct molecules in an orderly manner.
    Third, the reaction strategy of transition metal catalysis is also feasible. With the unique catalytic activity of transition metal catalysts, the precise construction of carbon-halogen bonds and carbon-carbon bonds can be achieved. For example, under the action of specific transition metal catalysts, fluorobenzene derivatives are coupled with bromine-containing and methylating reagents to achieve the synthesis of the target product. Although the conditions of this method are relatively mild, it requires strict catalyst selection and reaction system, and needs to be carefully regulated.
    When synthesizing 4-bromo-2- (bromomethyl) -1-fluorobenzene, it is necessary to consider the availability of starting materials, the difficulty of reaction conditions, yield and purity requirements, and carefully select a suitable synthesis method to prepare the compound efficiently and economically.
    What are the physical properties of 4-Bromo-2- (Bromomethyl) -1-Fluorobenzene?
    4-Bromo-2- (bromomethyl) -1-fluorobenzene is also an organic compound. It has specific physical properties, which are related to the properties of substances, melting boiling point, solubility and other characteristics. It is widely used in many fields such as chemical industry and medicine.
    This compound is mostly in solid or liquid state at room temperature and pressure, but the exact state depends on specific conditions. Looking at its melting point, there is a certain numerical range due to the characteristics of intermolecular forces and structures. Unfortunately, the exact melting point cannot be determined today, but it can be inferred that the existence of bromine, fluorine atoms and methyl groups in the molecule must have a significant impact on its melting point. The bromine atom has a large atomic radius and relative mass, which enhances the intermolecular force and increases the melting point; the fluorine atom has strong electronegativity, and although the atomic radius is small, it also contributes to the intermolecular force.
    In terms of boiling point, the same is true, and it is dominated by the intermolecular force. The relative molecular weight is large, and under the influence of bromine and fluorine atoms, the intermolecular force is enhanced, causing the boiling point to rise. This compound should have certain solubility in organic solvents, such as common ethanol, ether, dichloromethane, etc. Because it is an organic halogen, it has certain hydrophobicity and poor solubility in water.
    The color state of 4-bromo-2- (bromomethyl) -1-fluorobenzene may be colorless to light yellow, which is a common color state of many halogen-containing aromatic compounds. The density may be higher than that of water, due to its molecular composition and structure, and the molecular density increases due to the relatively heavy bromine and fluorine atoms.
    In summary, the physical properties of 4-bromo-2- (bromomethyl) -1-fluorobenzene lay the foundation for its behavior in various chemical reactions and practical applications. In-depth understanding of its properties is helpful for the rational application of this compound in related fields.
    What are the chemical properties of 4-Bromo-2- (Bromomethyl) -1-Fluorobenzene
    4-Bromo-2- (bromomethyl) -1-fluorobenzene is one of the organic compounds. Its chemical properties are unique and can be investigated.
    First of all, its halogenated hydrocarbon properties. The molecule contains bromine and fluorodihalogen atoms, and has the structure of bromomethyl. Bromine atoms are active and can undergo many substitution reactions. In the way of nucleophilic substitution, halogen atoms are easily replaced by nucleophiles. If encountered with alcohol nucleophiles, under suitable conditions, bromine atoms can be replaced by alkoxy groups to obtain corresponding ether compounds. This reaction needs to be catalyzed by alkali substances to seize the protons of nucleophiles and promote the reaction.
    Furthermore, the properties of the benzene ring should not be underestimated. The benzene ring is aromatic and can undergo electrophilic substitution reactions. Although there is a halogen atom and bromomethyl, the benzene ring can still interact with electrophilic reagents. For example, in the case of nitrifying reagents, nitro groups can be introduced into the benzene ring. Because the halogen atom and bromomethyl are ortho-para-sites, nitro groups are mostly introduced into its ortho-sites.
    The bromomethyl part is highly active because of the bromine atom attached to its α-carbon. Reactions such as with sodium cyanide can occur. The bromomethyl bromide is replaced by a cyanyl group to obtain a compound containing a cyanide group. This cyanyl group can be hydrolyzed into a carbox
    Because of its fluorine-containing atoms, fluorine atoms are highly electronegative, which has a significant impact on the electron cloud distribution of molecules, which in turn affects their reactivity and physical properties. It can affect the electron cloud density on the benzene ring and change the electrophilic substitution reactivity of the benzene ring.
    In summary, 4-bromo-2- (bromomethyl) -1-fluorobenzene is rich in chemical properties. In the field of organic synthesis, its characteristics can be used to construct complex organic compounds through various reactions, providing many possibilities for the research and practice of organic chemistry.
    What are the precautions for 4-Bromo-2- (Bromomethyl) -1-Fluorobenzene during storage and transportation?
    4-Bromo-2- (bromomethyl) -1-fluorobenzene is also an organic compound. During storage and transportation, many matters must not be ignored.
    First storage, this compound is active and should be stored in a cool, dry and well-ventilated place. Avoid direct sunlight to prevent its decomposition or other chemical reactions due to light. If the temperature is too high, it is easy to promote its deterioration, so the storage temperature should be controlled in a lower range. In addition, it is toxic and corrosive to a certain extent, and must be stored separately from oxidants, strong bases and other substances to avoid interaction and danger. And it needs to be placed out of the reach of children and locked for safekeeping.
    As for transportation, the packaging must be tight and reliable. Use suitable packaging materials to ensure that it will not be damaged or leaked during transportation. Transportation vehicles should be equipped with good ventilation equipment to dissipate gases that may leak. Transportation personnel must be professionally trained and familiar with the characteristics of this compound and emergency treatment methods. During transportation, drive carefully to avoid bumps, vibrations, and prevent damage to the packaging. In the event of a leak, it should be dealt with immediately according to the established emergency plan, evacuate surrounding personnel, seal the scene, strictly prohibit fireworks, and quickly use appropriate materials to absorb and clean up leaks to prevent pollution of the environment and endanger the safety of everyone.
    All of these are key considerations when storing and transporting 4-bromo-2- (bromomethyl) -1-fluorobenzene.