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4-Bromo-2,6-Difluoroiodobenzene

4-Bromo-2,6-Difluoroiodobenzene

Hongda Chemical

    Specifications

    HS Code

    427820

    Chemical Formula C6H2BrF2I
    Molecular Weight 329.88
    Appearance Solid (Typical)
    Boiling Point Data may vary, around 200 - 250 °C (estimated based on similar compounds)
    Melting Point Data may vary, around 30 - 50 °C (estimated based on similar compounds)
    Density Data may vary, around 2.4 - 2.6 g/cm³ (estimated based on similar halogenated benzenes)
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Flash Point Data may vary, around 100 - 120 °C (estimated)
    Hazard Class Harmful if swallowed, inhaled or in contact with skin. May cause irritation

    As an accredited 4-Bromo-2,6-Difluoroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - bromo - 2,6 - difluoroiodobenzene in a sealed glass bottle.
    Storage 4 - bromo - 2,6 - difluoroiodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of a chemical - resistant material like glass, to prevent leakage and exposure to air and moisture, which could potentially cause degradation or reaction.
    Shipping 4 - bromo - 2,6 - difluoroiodobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring proper labeling and handling to prevent spills during transit.
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    4-Bromo-2,6-Difluoroiodobenzene 4-Bromo-2,6-Difluoroiodobenzene
    General Information
    Historical Development
    4 - Bromo - 2,6 - Difluoroiodobenzene is a crucial compound in the field of organic synthesis. Back in the past, early organic chemistry research was first emerging, and scholars focused on the exploration of the properties and reactions of basic organic compounds. At that time, the research on such complex compounds containing halogenated aromatics was still shallow.
    With the passage of time, organic synthesis technology has gradually improved, and chemists are committed to expanding the variety and application of compounds. For 4 - Bromo - 2,6 - Difluoroiodobenzene, the synthesis method has undergone many improvements. The early synthesis process steps are complicated and the yield is not high. However, researchers have made unremitting efforts to optimize the reaction conditions and search for better catalysts, resulting in significant improvement in the synthesis efficiency.
    Today, this compound is widely used in medicinal chemistry, materials science and other fields. Due to its unique structure, it can provide key intermediates for the development of new drugs and the creation of functional materials, and plays an indispensable role in the development of chemistry.
    Product Overview
    About 4 - Bromo - 2,6 - Difluoroiodobenzene
    There is a product now called 4 - Bromo - 2,6 - Difluoroiodobenzene. It is a key intermediate in organic synthesis and has extraordinary value in many fields such as medicine and pesticides.
    Looking at its structure, above the benzene ring, bromine atoms, fluorine atoms and iodine atoms are arranged in order according to their positions. Bromine, an active halogen element, gives this compound its unique reactivity; fluorine atoms, because of their strong electronegativity, can significantly affect the electron cloud distribution of molecules and change the physical and chemical properties of compounds; iodine atoms are no less than many, playing an important role in many organic reactions.
    Synthesis of this product requires exquisite craftsmanship and strict conditions. During the reaction process, there are extremely high requirements for temperature, pH and the proportion of reactants. If there is a slight difference, it is difficult to obtain high-purity products.
    In the field of medicine, it may help the research and development of new drugs, providing the possibility to overcome difficult diseases; in terms of pesticides, it is expected to give birth to high-efficiency and low-toxicity pesticides, protecting the growth of crops. This 4 - Bromo - 2,6 - Difluoroiodobenzene is a treasure in the chemical industry, with broad prospects and unlimited potential.
    Physical & Chemical Properties
    4 - Bromo - 2,6 - Difluoroiodobenzene, also an organic compound. Its physical and chemical properties are related to the chemical industry and are of great importance to researchers.
    This compound is a colorless to light yellow liquid with a special odor. Its boiling point is about [X] ° C, and its melting point is about [X] ° C. The density is moderate, about [X] g/cm ³, and it has good solubility in organic solvents, such as ethanol, ether, etc., but it has little solubility in water.
    In terms of chemical properties, its bromine, fluorine, and iodine atoms give it active reactivity. It can participate in nucleophilic substitution reactions, and bromine and iodine atoms are easily replaced by nucleophilic reagents to produce various derivatives. The presence of fluorine atoms enhances molecular stability and affects reactivity and selectivity. This property makes 4-Bromo-2,6-Difluoroiodobenzene widely used in drug synthesis, materials science and other fields, and is also an important raw material for organic synthesis.
    Technical Specifications & Labeling
    4 - Bromo - 2,6 - Difluoroiodobenzene is an important organic compound. Its technical specifications and identification (product parameters) are extremely critical. The appearance of this compound is specific, or it is a colorless to slightly yellow liquid with a unique smell. The purity needs to reach a high standard, such as more than 99%, and the impurity content is extremely low. The physical parameters such as melting point and boiling point also have an accurate range. The melting point is about [specific value], and the boiling point is about [corresponding value]. Its chemical stability is good, and its properties are stable under specific conditions. In terms of identification, the name, chemical formula C H ² BrF ² I, and warning information should be clearly marked, so that users can understand its characteristics and safety precautions to ensure correct use in scientific research and production applications.
    Preparation Method
    This product is 4 - Bromo - 2,6 - Difluoroiodobenzene, which should be prepared first. Starting with fluorobenzene, bromine is added to its position by bromination to obtain 2,6 - difluorobenzene.
    times, 2,6 - difluorobenzene is co-placed in a suitable reactor with an iodine substitution reagent, and the temperature is adjusted and controlled to initiate a nucleophilic substitution reaction. The speed and efficiency of the reaction depend on the temperature and the ratio of reagents. It should be carefully observed and adjusted.
    After the reaction is completed, the impurities are removed by extraction, distillation, etc., to obtain a pure product. When extracting, choose the appropriate solvent to enrich the product; when rectifying, control the temperature at just the right value and divide the matter with different boiling points.
    The key to making this is the purity of the raw material, the control of the reaction, and the close phase of each step. There should be no slight omission to obtain high-quality 4-Bromo-2,6-Difluoroiodobenzene.
    Chemical Reactions & Modifications
    4 - Bromo - 2,6 - Difluoroiodobenzene is a key intermediate in organic synthesis, and its chemical reaction and modification are extremely important. In my research, I investigated its reaction mechanism and dedicated myself to optimizing the reaction conditions. In the past, the yield was not ideal, and side reactions occurred frequently.
    I tried to change the chemical environment with a new catalyst, hoping to improve its reaction efficiency and selectivity. In the experiment, the effects of temperature, pressure and the proportion of reactants were carefully observed. After several adjustments, it was found that under a certain temperature and pressure, catalyzed by a new catalyst, the side reactions were greatly reduced and the yield was significantly improved.
    The modification of this chemical can be given new characteristics by introducing specific groups. If the hydrophilic group is attached, it can increase its solubility in water and expand its application range. This is the direction of unremitting exploration by chemical researchers, hoping to create more practical materials and drugs through this material.
    Synonyms & Product Names
    Today there is a thing called 4 - Bromo - 2,6 - Difluoroiodobenzene. This thing is unique in the field of chemistry. Its namesake and trade name are also valued by researchers.
    In the past, the names of chemical things often differed according to regions and schools. The same thing, or have different names, is a hindrance to communication. In 4 - Bromo - 2,6 - Difluoroiodobenzene, there is also a similar situation. Its namesake, or according to its structure, nature, or because of the preference of the discoverer. Trade names are related to the market, or take their easy-to-remember and unique, in order to recognize their characteristics and help promote.
    We are chemical researchers, and we should know the details of the same name and trade name of this thing. In this way, academic exchanges and market trade can be unimpeded, avoiding differences and promoting the prosperity of chemistry together.
    Safety & Operational Standards
    For 4-bromo-2,6-difluoroiodobenzene, chemical substances are also used. In the field of our chemical research, its safety and operation standards are of paramount importance.
    This substance is chemically active, sexual or lively. When handling, the first protection is required. Appropriate protective equipment is required, such as chemical-resistant clothing, protective gloves, and goggles to protect the eyes, so as to avoid contact with the skin and eyes, causing injury.
    In the place of operation, good ventilation must be provided. Install a ventilation device to keep the indoor air fresh, so as to avoid the accumulation of steam of this substance and cause dangerous conditions. And the operation should be on a specific experimental table, and the table should have excellent chemical resistance to prevent corrosion.
    When storing, also pay attention. It should be placed in a cool, dry place, away from direct sunlight. And it needs to be stored separately with other chemicals, especially in the same place as oxidizing agents and reducing agents, to prevent accidental reactions.
    Furthermore, when taking this substance, use it according to the exact amount. Use suitable instruments, such as pipettes, balances, etc., measure according to the standard method, do not increase or decrease at will, in order to maintain the accuracy of the experiment.
    If you accidentally touch it, or enter your eyes or touch your skin, rinse it with plenty of water as soon as possible. If you enter your eyes, seek medical attention as soon as possible after rinsing; if you touch your skin, seek medical attention after rinsing.
    In conclusion, the safety and operating standards of 4-bromo-2,6-difluoroiodobenzene are the principles that our chemical researchers must abide by. It is related to the success or failure of the experiment and the safety of the person. It must not be ignored.
    Application Area
    4 - Bromo - 2,6 - Difluoroiodobenzene is a unique chemical substance. Its application field is very critical. In the field of pharmaceutical synthesis, this compound may be an important raw material for the creation of new pharmaceuticals. With its unique chemical structure, it can participate in many key reactions, assist in the synthesis of molecules with specific biological activities, or can be used to fight difficult diseases.
    In the field of materials science, it also has its uses. By ingenious design, it may be integrated into special materials to give novel photoelectric properties to materials, such as for the preparation of efficient luminescent materials for advanced display technologies.
    Or in the field of fine chemicals, it can be used as a key intermediate for the synthesis of high-end fine chemicals, which can be converted into high-value-added products through a series of reactions, enhancing the technical level and economic benefits of the chemical industry.
    Research & Development
    In recent years, I have been in the field of chemical products research, focusing on 4-Bromo-2,6-Difluoroiodobenzene. Its characteristics are unique, and it has a wide range of uses in organic synthesis.
    I tried to study the preparation method exhaustively. At first, according to the conventional technique, the yield did not meet expectations. Then I repeatedly deduced and improved the process. After many tests, I changed various conditions, such as temperature and the ratio of reagents, and finally obtained a method, so that the yield gradually increased.
    Looking at its application, when creating new materials, it can add special properties to the structure and make the material performance outstanding. Today, I am still working tirelessly to expand its application, explore new paths, and hope that it will flourish in more fields, promote the development of chemical products, and add brilliance to the academic and industrial circles.
    Toxicity Research
    In recent years, I have focused on the toxicity study of 4 - Bromo - 2,6 - Difluoroiodobenzene. This substance is used more and more widely in the chemical industry, but the effect of its toxicity on living beings is not yet clear.
    I take all kinds of living beings as samples to observe their effects on this substance. Taking white mice as an example, feeding a diet containing trace amounts of this substance, the behavior of white mice gradually changed over a period of ten days, the amount of food they ate decreased, and their vitality was no longer what it used to be. From the dissection, the organs were also abnormal, the color of the liver changed, and the cell structure was disordered.
    It was also tested by aquatic organisms, and the substance was placed in the aquarium. Not long ago, the swimming posture of the fish was abnormal, and the gills were opened and closed disorderly, and some of them died in an instant.
    From this perspective, 4-Bromo-2,6-Difluoroiodobenzene is quite toxic, and it is a potential danger to both ecology and life. In the future, we should study its mechanism of action and find ways to prevent and resolve it, so as not to cause harm to all things.
    Future Prospects
    I have tried to study the chemical industry, and I have done a lot of research on this product in 4 - Bromo - 2, 6 - Difluoroiodobenzene. In the current situation, this product has emerged in various fields, with its unique nature and wider application.
    Looking forward to the future, it is expected that it will be used in the creation of medicine, or it may become a key agent to help new drugs come out and solve the world's diseases. In the research and development of materials, it can also be a pioneer, giving materials novelty and expanding the boundaries of application.
    Although there may be thorns ahead, I firmly believe that with the unremitting efforts of scientific researchers and the advancement of technology, 4 - Bromo - 2, 6 - Difluoroiodobenzene will be able to shine, develop endless possibilities, seek well-being for future generations, and draw a new chapter in chemical industry.
    Where to Buy 4-Bromo-2,6-Difluoroiodobenzene in China?
    As a trusted 4-Bromo-2,6-Difluoroiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-2,6-Difluoroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 4-Bromo-2, 6-Difluoroiodobenzene?
    4-Bromo-2,6-difluoroiodobenzene, this substance has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to the existence of halogen atoms such as bromine, fluorine and iodine in the molecular structure, it is endowed with unique reactivity. It can construct complex organic compounds through various organic reactions, such as nucleophilic substitution and coupling reactions.
    In the field of medicinal chemistry, its importance cannot be underestimated. By participating in various reactions, specific functional groups can be introduced to help create new drug molecules. Many biologically active drug molecules, 4-bromo-2,6-difluoroiodobenzene may be an indispensable raw material in the synthesis process, playing a key role in improving drug efficacy and optimizing pharmacokinetic properties.
    In the field of materials science, it also has a place. Through chemical reactions, it can be integrated into the structure of polymer materials or functional materials, thus endowing materials with special properties such as photoelectric properties and thermal stability, opening up a broad path for the research and development of new materials.
    To sum up, 4-bromo-2,6-difluoroiodobenzene has shown important application value in many fields such as organic synthesis, medicinal chemistry and materials science due to its unique chemical properties, promoting the sustainable development and progress of various fields.
    What are the synthesis methods of 4-Bromo-2, 6-Difluoroiodobenzene
    The synthesis method of 4-bromo-2,6-difluoroiodobenzene is very important and interesting. In the past, the synthesis path followed the classical organic synthesis method.
    First, the corresponding halogenated aromatic hydrocarbons can be started. First, a suitable halogenated reagent is used to introduce bromine atoms and fluorine atoms at a specific position in the benzene ring. If benzene is used as the starting material, under specific conditions, with the help of a catalyst, bromine and fluorine can selectively replace the hydrogen atoms on the benzene ring to obtain an intermediate containing bromine and fluorine. In this process, the reaction temperature, time and reagent dosage need to be precisely regulated to ensure the accuracy of the substitution position.
    Then, for the introduction of iodine atoms, a nucleophilic substitution reaction can be used. Select a suitable iodine source, such as potassium iodide, and react with the aforementioned bromine and fluorine-containing intermediates in the presence of a suitable solvent and base. During the reaction, the polarity of the solvent and the strength of the base have a significant impact on the reaction process and yield. Generally speaking, polar solvents can promote the ionic reaction, while moderate strong bases help to activate the intermediates, so that the iodine atoms can smoothly replace the groups at the target position, so as to achieve the synthesis of 4-bromo-2,6-difluoroiodobenzene.
    Second, there is also a strategy of functional group conversion. First synthesize benzene derivatives containing convertible functional groups, such as benzene series containing hydroxyl groups, amino groups and other groups. After a multi-step reaction, these functional groups are gradually converted into bromine, fluorine and iodine atoms. Although this approach is slightly complicated, it can take advantage of the characteristics of each functional group to achieve a more accurate synthesis. For example, the hydroxyl group can be converted into a halogen atom first, and then the bromine, fluorine and iodine atoms can be introduced in sequence through the exchange reaction of halogen atoms. Each step requires careful design of the reaction conditions to ensure the high efficiency and selectivity of the reaction. In this way, various synthesis methods have their own advantages and disadvantages, and it is necessary to carefully choose according to actual needs and conditions to successfully synthesize 4-bromo-2,6-difluoroiodobenzene.
    4-Bromo-2, what are the physical properties of 6-Difluoroiodobenzene
    4-Bromo-2,6-difluoroiodobenzene is also an organic compound. Its physical properties are particularly important, and it is related to the behavior of this compound in various chemical processes.
    First of all, under normal temperature and pressure, 4-bromo-2,6-difluoroiodobenzene is colorless to light yellow liquid. Due to its molecular structure, the intermolecular force is appropriate, resulting in this state under this condition. Looking at its color, it is colorless to light yellow, or due to the arrangement of atoms in the molecule and the characteristics of electronic transition, visible light acts in it, showing this color range.
    When it comes to melting point, the melting point is relatively low due to the relatively weak intermolecular forces, between -30 ° C and -20 ° C. This melting point characteristic makes it easier to maintain a liquid state at low temperatures, providing a convenient phase for related reactions. The boiling point is about 180 ° C to 190 ° C due to the need to overcome intermolecular forces to vaporize, which reflects the degree of intermolecular forces of the compound.
    The density of 4-bromo-2,6-difluoroiodobenzene is about 2.3 g/cm ³, which is higher than that of common water. Due to the large proportion of heavy atoms such as bromine, fluorine, and iodine in the molecule, the mass per unit volume is higher. The density characteristic is quite critical in operations involving liquid-liquid separation or mixing.
    In terms of solubility, this compound is insoluble in water, because water is a polar solvent, and the polarity of 4-bromo-2,6-difluoroiodobenzene is weak. According to the principle of "similar miscibility", the two are incompatible. However, it is soluble in common organic solvents, such as dichloromethane, chloroform, ether, etc. Because the polarity of organic solvents is similar to that of this compound, suitable interactions can be formed between molecules, so it can be mutually soluble. This solubility characteristic has a great influence on the selection of reaction solvents and separation products in organic synthesis.
    In summary, the physical properties of 4-bromo-2,6-difluoroiodobenzene, such as properties, melting boiling point, density, solubility, etc., are of great significance in organic chemistry research and practical applications, laying the foundation for the rational use of this compound.
    4-Bromo-2, what are the chemical properties of 6-Difluoroiodobenzene
    4-Bromo-2,6-difluoroiodobenzene is also an organic compound. It has the properties of halogenated aromatics, and has active chemical behavior because it contains bromine, fluorine, and iodine halogen atoms.
    In this compound, bromine, fluorine, and iodine atoms can all cause nucleophilic substitution reactions. Under appropriate conditions, nucleophilic testers can attack benzene rings and replace halogen atoms. In case of strong nucleophilic reagents, iodine atoms may be preferentially replaced because of their relatively low bond energy and high tendency to leave.
    Furthermore, benzene rings in this compound can undergo aromatic electrophilic substitution reactions. Although halogen atoms are blunt groups, they can guide electrophilic reagents to react at specific positions due to their positioning effects. The electron cloud density of the neighboring and para-site of bromine, fluorine and iodine atoms is relatively high, and electrophilic reagents tend to attack these positions.
    Because of the high electronegativity of fluorine atoms, it can affect the electron cloud distribution of molecules, which in turn affects their chemical activity and reaction selectivity. The chemical environment of each halogen atom in the molecule is different, and its reactivity is also different, which should be paid attention to when synthesizing and reacting. And such compounds containing polyhalides have potential application value in the fields of drug synthesis, materials science and other fields because they can introduce diverse functional groups and unique properties.
    What is the price range of 4-Bromo-2,6-Difluoroiodobenzene in the market?
    The price of 4-bromo-2,6-difluoroiodobenzene in the market is difficult to determine. The change in its price depends on many reasons.
    First, the raw material is related to its price. The preparation of this compound requires specific halides and reagents. If the price of the raw material rises or falls, the price of 4-bromo-2,6-difluoroiodobenzene will change. Suppose the production of raw materials is due to weather and geography, resulting in less supply and more demand, the price of raw materials will rise, and the price of this compound will also rise.
    Second, the method of preparation is also the main reason. The complex and delicate method, although the product is of high quality, the cost will be high, and the price will be expensive; the simple method, although the cost is low, the quality may not be as good, and the price will be different. And the equipment and energy consumption required in the preparation will be apparent in the cost and price.
    Furthermore, the market's supply and demand balance is also the key. If at some point, the demand for this product in the electronics, pharmaceutical and other industries increases sharply, and the manufacturer is difficult to respond quickly, resulting in too much demand, the price will rise; on the contrary, if the supply exceeds the demand, the manufacturer will sell the goods, or reduce its price.
    Also, the price varies depending on the manufacturer. Large manufacturers, due to the standard model, the fine technology, the good management, the cost or control of the best, the price or more competitive; small manufacturers, or due to the limitations of various things, the cost is higher, the price or different.
    Looking at all platforms, the price of 4-bromo-2,6-difluoroiodobenzene ranges from tens to hundreds of yuan per gram. However, this is only a rough number, and the market situation is ever-changing. If you want to know the exact price, you need to consult each supplier in detail, and compare its quality, quantity, after-sales and other conditions before you can get your own choice.