4-Bromo-2,5-Difluoronitrobenzene

Hongda Chemical

Specifications

HS Code	296137
Chemical Formula	C6H2BrF2NO2
Appearance	Typically a solid
Color	May be colorless to pale yellow
Melting Point	Data needed
Boiling Point	Data needed
Density	Data needed
Solubility In Water	Low solubility, likely insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Flash Point	Data needed
Vapor Pressure	Data needed
Stability	Stable under normal conditions, but may react with strong oxidizing agents
Hazard Class	Irritant, may be harmful if swallowed, inhaled or in contact with skin

As an accredited 4-Bromo-2,5-Difluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 4 - bromo - 2,5 - difluoronitrobenzene packaged in a sealed glass bottle.
Storage	4 - bromo - 2,5 - difluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent leakage and exposure to air and moisture. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential chemical reactions.
Shipping	4 - bromo - 2,5 - difluoronitrobenzene is shipped in sealed, corrosion - resistant containers. It adheres to strict chemical shipping regulations, ensuring proper handling to prevent spills and environmental/health risks during transit.

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General Information

Historical Development

4-Bromo-2,5-difluoronitrobenzene is also a treasure of chemistry. Although it is difficult to test the exact time when it first appeared, looking at the progress of chemical technology, this product has gradually entered the public eye. In the past, chemical sages studied the properties and changes of substances, and in the genus of halogenated nitrobenzene, they explored them diligently.
At the beginning, the preparation method was still simple and crude, and the amount obtained was also thin. After repeated research, various ingenious methods gradually emerged, and the yield and purity were improved. Scholars strive for excellence in the conditions of reaction and the selection of reagents. Therefore, 4-bromo-2,5-difluoronitrobenzene has gradually developed its use in chemical, pharmaceutical and other fields, making outstanding contributions to the prosperity of the industry. Its historical evolution is actually a corner of the development of chemistry, and it also witnesses the unremitting pursuit of human beings in science.

Product Overview

4-Bromo-2,5-difluoronitrobenzene is the key substance involved in the research of chemical products. This product has unique properties and is in the form of white to light yellow crystalline powder, which is widely used in the field of chemical synthesis.
Its preparation method has been studied many times, and a specific halogenation and nitrification process path has been adopted. Under suitable reaction conditions, the proportion of reactants is carefully adjusted, temperature control and time control, and this product is finally obtained.
In terms of its application, it is particularly important for the synthesis of pharmaceutical intermediates. With it as a cornerstone, many bioactive molecular structures can be built, which is expected to provide assistance for the development of new drugs. And in the field of materials science, there may also be potential applications that can improve some properties of materials.
However, the research process is not smooth sailing, such as the improvement of reaction yield and the removal of impurities. We need to work hard to find a better solution, hoping to push the performance and application of this chemical to a new level.

Physical & Chemical Properties

4 - Bromo - 2,5 - Difluoronitrobenzene, organic compounds are also. Its physical properties are solid at room temperature, with a light yellow color and a special odor. The melting point is suitable, about [X] ° C, this characteristic allows it to maintain its inherent form in a specific temperature environment. The boiling point is also characterized, at about [X] ° C, it vaporizes when heated.
Its chemical properties are active, because it contains functional groups such as bromine, fluorine, and nitro. Bromine atoms are highly active and easily participate in substitution reactions, which can be replaced by other groups. Fluorine atoms have strong electronegativity, which makes molecular electron clouds different and affects the reaction activity and selectivity. Nitro groups have strong electron-absorbing properties, which reduce the electron cloud density of the benzene ring, increase the difficulty of electrophilic substitution reactions, but nucleophilic substitution reactions are more likely to occur. This compound is often a key intermediate in the field of organic synthesis, and many organic products can be derived through various reaction paths.

Technical Specifications & Labeling

4 - Bromo - 2,5 - Difluoronitrobenzene is an important chemical substance. Its process specifications and identification (product parameters) are crucial.
In terms of process specifications, the synthesis process needs to be precisely controlled. From the selection of raw materials, high-purity starting materials should be selected, such as fluorobenzene derivatives and brominating reagents of specific purity. The reaction conditions must also be strictly controlled, the temperature should be controlled in a certain precise range, and the pressure should also be appropriate to ensure the efficient and directional reaction.
On the label (product parameters), the appearance should be a specific color and shape, such as white to slightly yellow crystalline powder. The purity must reach a very high standard, and the impurity content is strictly limited. Melting point, boiling point and other physical parameters should also conform to the established range, so as to ensure product quality and meet the needs of all parties.

Preparation Method

4 - Bromo - 2,5 - Difluoronitrobenzene is an important chemical raw material, and its preparation method is related to the raw material and production process, reaction steps and catalytic mechanism.
Preparation of raw materials, when taking appropriate starting materials, such as aromatic hydrocarbons containing bromine, fluorine and nitro groups. The production process requires fine planning, from the control of reaction conditions to the purification of the product, all must be rigorous.
For the reaction step, the initial reaction is often halogenation reaction to introduce bromine and fluorine atoms. Conditions may require specific catalysts and solvents to ensure that the reaction proceeds in the desired direction. The subsequent nitration reaction should also be precisely controlled, and the appropriate nitrification reagent and reaction temperature should be selected to ensure the purity and yield of the product.
The catalytic mechanism is very critical, and the appropriate catalyst can greatly improve the reaction rate and selectivity. For example, metal catalysts can promote the substitution of halogen atoms in the halogenation step, while in the nitration, specific acidic catalysts may optimize the reaction path.
In this way, 4-Bromo-2,5-Difluoronitrobenzene can be efficiently prepared after careful preparation of raw materials, planning process, controlling steps and clarifying catalytic mechanism.

Chemical Reactions & Modifications

To taste the way of chemical industry, it is important to develop new ones. Today there are 4 - Bromo - 2,5 - Difluoronitrobenzene this substance, which is in the field of chemistry and is related to the wonder of reaction and modification.
Looking at the reaction, many paths can be followed. Or in a specific medium, a catalyst can be used to accompany it, so that it encounters a certain reagent and undergoes a substitution change, so that atoms such as bromine and fluorine can be translocated to derive new compounds. This reaction condition needs to be carefully controlled. Temperature and humidity, and the proportion of reagents are all key. If there is a slight difference, the results will be very different.
When it comes to modification, a group can be added to it by chemical means. For example, a hydrophilic group is introduced to increase its solubility in the aqueous phase and broaden the field of application. Or add stabilizing groups to strengthen its structure and improve chemical stability. All these are the research directions of chemical researchers, hoping to use this substance as a basis to open up new frontiers and add bricks and mortar to the prosperity of chemical industry.

Synonyms & Product Names

Today there is a thing called 4 - Bromo - 2,5 - Difluoronitrobenzene. This thing is very important in my chemical research. What is its different name? Although it is recorded in the ancient books, there is no mixed name, but it is not known in the industry, or it is called by a simple name.
As for the name of the product, the merchant is to recognize its uniqueness, or to take a unique name to attract people's attention. However, it all revolves around its essential characteristics, hoping to show its difference from other things. Although it is not widely known by the names of its many products, it is necessary for the merchant to be attentive, to pass on its quality by name, and the user knows its use by knowing its name. For the needs of the chemical industry, this thing can be selected to achieve all things. We are also looking forward to the name of the market, which is clear and clear, to help the industry flow smoothly, and to promote the progress of research.

Safety & Operational Standards

4 - Bromo - 2,5 - Difluoronitrobenzene Safety and Operation Specifications
F 4 - Bromo - 2,5 - Difluoronitrobenzene, a substance commonly used in chemical research. If you want to make good use of this substance, you must first clarify its safety and operation specifications.
This substance is dangerous. Its bromine, fluorine, nitro and other atomic groups coexist, or cause complex variables of chemical reactions. Bromine is active, or reacts with other substances such as halogenation; nitro is oxidizing, and it may explode when exposed to reducing agents, heating, etc.; the presence of fluorine atoms also greatly increases the chemical activity of molecules. Therefore, when storing, it is necessary to choose a cool, dry and well-ventilated place, away from fire and heat sources, and store it separately from reducing agents, flammable substances, etc., and must not be mixed to avoid accidents.
When operating, be strict. The experimenter is in front of appropriate protective equipment, such as protective clothing, protective gloves and protective glasses, to prevent skin contact and splashing into the eyes. The operating environment should have good ventilation facilities to dissipate harmful gases that may escape. When weighing, the action should be slow and precise to avoid powder flying and increase the concentration of harmful substances in the air.
If you accidentally come into contact with this object, you should deal with it quickly. For skin contact, rinse immediately with a large amount of flowing water, followed by soap, if you feel unwell, seek medical attention immediately. Eye contact, immediately lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline, and seek medical attention in time. If inhaling its volatile gas, quickly leave the scene to a fresh air, keep the respiratory tract unobstructed, if breathing difficulties, give oxygen, stop breathing, perform artificial respiration and seek medical attention.
In short, 4 - Bromo - 2,5 - Difluoronitrobenzene Although useful in chemical research, its safety and operating standards should not be ignored, so as to ensure the safety of the experiment and the smooth research.

Application Area

4 - Bromo - 2,5 - Difluoronitrobenzene is a unique chemical substance. In various application fields, it shows unique functions. In the field of pharmaceutical research and development, it may be a key intermediate for the synthesis of specific drugs. Through delicate chemical reactions, it can be integrated into the molecular structure of drugs, giving drugs specific biological activity and pharmacological efficacy. In the field of materials science, it can be chemically modified to prepare materials with special optoelectronic properties, such as in advanced display technology or high-performance sensors, because of its unique molecular structure, or can regulate the electronic transport and optical response characteristics of materials. In organic synthetic chemistry, it is also an important building block for the construction of complex organic molecules, enabling chemists to create a variety of novel organic compounds, expanding the research boundaries of organic chemistry, and providing a key material foundation and innovation opportunity for the development of various related fields.

Research & Development

Today there is a substance called 4 - Bromo - 2,5 - Difluoronitrobenzene. I am a researcher of chemicals, and I have been very attentive to the research and development of this substance.
When I first came into contact with this substance, I felt that its structure is exquisite, bromine, fluorine and nitro are combined in the benzene ring, and its characteristics are unique. So I thought about the method of its synthesis, and after many attempts, I adjusted the temperature or changed the solvent, and strived for accuracy. Also explore its reactivity, observe its changes in different reagents, and know which one it can respond to and which one can make new substances.
Looking at its application in the field of medicine, it is expected to be the foundation of new pharmaceuticals. With its characteristics, it may be able to break difficult diseases; in the field of materials, it may be able to become new materials and increase the ability of materials. Although the road ahead is long, I firmly believe that through unremitting research, this thing will be able to shine, and on the road of research and development, it will take a solid step, be used by the world, and benefit people.

Toxicity Research

The toxicity of 4-Bromo-2,5-Difluoronitrobenzene is studied. This substance contains bromine, fluorine, nitro and other groups, which may be potentially harmful. Its bromine atom has high activity, or it may initiate chemical reactions in the body and interfere with biochemical processes. Fluorine has strong electronegativity, which can affect molecular stability and reactivity, or cause toxic aberration. Nitro is a strong electron-absorbing group, which changes the electron cloud density of the benzene ring, or involves a toxic mechanism.
In vivo, or through metabolic transformation, produces active intermediates, which damage cell structure and function. Looking at its structure, it can be seen that it is similar to many toxic substances, such as the toxicology of halogenated aromatics, or cell damage caused by electrophilic substitution and oxidative stress. Although there is no detailed toxicological report, it is inferred from the structure that attention should be paid to its potential toxicity, and the experimental operation must be careful to prevent exposure and pollution, and ensure environmental and personal safety.

Future Prospects

Husband 4 - Bromo - 2,5 - Difluoronitrobenzene, it is also a thing of transformation. Its future prospects can be deeply considered. This compound may have new encounters in the way of material research. With its special creation, it may lead to new life and save people.
And in the field of material science, it may also be a big color. Or it can be turned into the cornerstone of high-performance materials, helping aerospace, children, etc.
However, if we want to achieve this state, we still need to research the heart of the chemical researcher, explore its nature, and explore its secrets. With unremitting efforts, we can make 4 - Bromo - 2,5 - Difluoronitrobenzene the ability to benefit the world and achieve extraordinary things.

Where to Buy 4-Bromo-2,5-Difluoronitrobenzene in China?

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Frequently Asked Questions

As a leading 4-Bromo-2,5-Difluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 4-Bromo-2, 5-Difluoronitrobenzene?

4-Bromo-2,5-difluoronitrobenzene is a key intermediate in organic synthesis and is widely used in many fields.
First, in the field of medicinal chemistry, it is an important raw material for the synthesis of specific drugs. Many new antibacterial and antiviral drugs are created by relying on this as the starting material. Through fine chemical reactions, specific functional groups are added to shape unique chemical structures, resulting in excellent biological activity, which can accurately act on pathogenic targets and effectively treat various diseases.
Second, in the field of pesticide chemistry, new pesticides with high efficiency, low toxicity and environmental friendliness can be prepared. After ingenious design, a specific molecular structure is constructed, which makes it have a strong toxic effect on pests, or interferes with their growth and reproduction process, and has a slight impact on non-target organisms, making a great contribution to ensuring crop harvest and maintaining ecological balance.
Third, in the field of materials science, it also plays an important role. It can be used to synthesize high-performance organic optoelectronic materials, such as organic Light Emitting Diode (OLED) materials. Its unique molecular structure gives the material excellent photoelectric properties, improves the luminous efficiency, stability and color purity of the device, and promotes the continuous improvement of display technology.
Furthermore, in the study of organic synthetic chemistry, it is the cornerstone of the construction of complex organic molecules. Because it contains a variety of active functional groups, it can couple with various reagents through multiple reactions such as nucleophilic substitution and electrophilic substitution to build a rich and diverse organic framework, providing a broad space for chemists to explore the structure and properties of new compounds.
In short, 4-bromo-2,5-difluoronitrobenzene plays a key role in the fields of medicine, pesticides, materials and organic synthesis due to its unique chemical properties, and continues to promote innovation and development in various fields.

4-Bromo-2, what are the physical properties of 5-Difluoronitrobenzene

4-Bromo-2,5-difluoronitrobenzene is one of the organic compounds. It has the following physical properties:
Looking at its appearance, under normal temperature and pressure, it often takes the form of a white-like to light yellow crystalline powder. This form is easy to identify and has visual characteristics.
As for the melting point, it is about 50-54 ° C. The melting point is the critical temperature at which the substance changes from solid to liquid. This property is very important when distinguishing and purifying the compound. When the temperature gradually rises to the melting point range, the compound slowly melts from solid to liquid, like ice and snow melting when warm.
Its boiling point is about 254.4 ° C. Boiling point, the temperature at which the saturated vapor pressure of a liquid is equal to the external pressure. At this temperature, the liquid will vaporize violently, which is an important physical transformation of the substance at high temperature. At this boiling point, 4-bromo-2,5-difluoronitrobenzene will change from liquid to gaseous state.
4-bromo-2,5-difluoronitrobenzene is insoluble in water, because water is a polar solvent, and the molecular structure of the compound is polar, so it interacts weakly with water and is therefore insoluble. However, it is soluble in organic solvents such as dichloromethane, chloroform, and toluene. The polarity and molecular structure of organic solvents vary, and the compounds can interact with van der Waals forces, hydrogen bonds, etc., so that they can be uniformly dispersed. This solubility is of great significance in the process of organic synthesis and separation, and can help chemists select suitable solvents for various reactions and operations according to their characteristics.

What are the synthesis methods of 4-Bromo-2, 5-Difluoronitrobenzene

There are various ways to synthesize 4-bromo-2,5-difluoronitrobenzene. Common ones can be started from nitrobenzene and formed by halogenation.
First, the nitrobenzene is first used under specific conditions with suitable halogenating reagents, such as brominating agents and fluorinating agents, in sequence or at the same time. In appropriate solvents, such as halogenated hydrocarbon solvents, control factors such as temperature, reaction time and reagent ratio. Too high or too low temperature may affect the reaction rate and product selectivity. If the temperature is too high, or side reactions will increase, resulting in unnecessary polyhalogenated products; if the temperature is too low, the reaction will be slow and take a long time. The reaction time must also be precisely controlled. If it is too short, the reaction will not be completed, and the product will be impure. If it is too long, it will increase the cost and may also lead to side reactions. The proportion of reagents is also critical. If the amount of brominating agent and fluorinating agent is not appropriate, the substitution position and number of bromine atoms and fluorine atoms may deviate from expectations.
Second, it can also be started from benzene derivatives containing bromine and fluorine, and the target product can be obtained through nitrification reaction. At this time, the choice of nitrification reagents is very important. The commonly used nitric acid and sulfuric acid mixed system needs to adjust its concentration and ratio. Sulfuric acid is not only a solvent, but also helps to generate nitroyl cations, which is an active intermediate for nitrification reactions. The reaction conditions also need to be carefully regulated. Factors such as temperature and reaction time are all related to the Due to the presence of bromine and fluorine substituents on the benzene ring, the electronic and spatial effects will affect the regioselectivity of the nitrification reaction.
In addition, the reaction catalyzed by transition metals can also be considered to achieve the precise introduction of bromine, fluorine and nitro groups. Although this method may be complicated, the selectivity is often better. Transition metal catalysts can promote the coupling reaction of halogen atoms and benzene rings, and the precise progress of nitrification reactions. However, such methods require harsh reaction conditions, and the choice and dosage of catalysts, as well as the design of ligands, need to be carefully considered.
In summary, the synthesis of 4-bromo-2,5-difluoronitrobenzene requires comprehensive consideration of many factors such as starting materials, reaction conditions, and reagent selection. Only after careful optimization can the ideal product yield and purity be obtained.

4-Bromo-2, 5-Difluoronitrobenzene What are the precautions during storage and transportation?

4-Bromo-2,5-difluoronitrobenzene is a commonly used raw material in organic synthesis. During storage and transportation, many matters need to be paid careful attention.
Its properties have certain chemical activity, and in case of hot topics, open flames or strong oxidants, there is a risk of combustion and explosion. Therefore, when storing, it should be placed in a cool and ventilated warehouse, away from fire and heat sources, and the storage temperature should not exceed 30 ° C. It should be stored separately from oxidizing agents, reducing agents, and alkalis. Do not mix storage to prevent dangerous chemical reactions.
Where it is stored, suitable materials should be prepared to contain leaks. Because if it leaks, it may cause harm to the environment and human body. When transporting, it is also necessary to ensure that the container does not leak, collapse, fall or damage. The transport vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment.
During transportation, it is necessary to prevent exposure to the sun, rain and high temperature. When transporting by road, it is necessary to follow the prescribed route and do not stop in residential areas and densely populated areas. The escort personnel should also be familiar with the characteristics of this object and emergency treatment methods, so as to ensure the safety of storage and transportation and avoid disasters.

4-Bromo-2, 5-Difluoronitrobenzene impact on the environment and human health

4-Bromo-2,5-difluoronitrobenzene is also an organic compound. It is used in industrial synthesis, or has specific uses. However, this substance has potential effects on the environment and human health.
As far as the environment is concerned, if it is released in nature, it may be difficult to degrade. Because of its halogen atoms and nitro groups, the structure is stable. In soil, it may cause soil pollution, affecting the activity of soil microorganisms and soil fertility, and then disturbing the growth of plants. In water, it may harm aquatic organisms. Its toxicity or cause death of fish, plankton, etc., destroy the balance of aquatic ecosystems, and will also enrich with the food chain, harming more advanced organisms.
As for human health, 4-bromo-2,5-difluoronitrobenzene is toxic. Inhalation through the respiratory tract, or irritating the respiratory mucosa, causing cough, asthma and other diseases, long-term inhalation, or damage to lung function. If it is exposed to or penetrates the skin, it will cause skin allergies, redness, swelling, itching, etc., and in severe cases, it may cause systemic poisoning. Ingestion through the mouth may damage the digestive system, cause nausea, vomiting, abdominal pain, etc., or damage the liver, kidneys and other organs. Because of its metabolism in the body, toxic metabolites are produced, which affect the normal function of organs. Therefore, in the production and use of 4-bromo-2,5-difluoronitrobenzene, strict safety procedures must be followed to properly dispose of waste to reduce its harm to the environment and human health.