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4-Bromo-2,3-Difluoroiodobenzene

4-Bromo-2,3-Difluoroiodobenzene

Hongda Chemical

Specifications

HS Code

141673

Chemical Formula C6H2BrF2I
Molecular Weight 329.88
Appearance Typically a colorless to light - colored liquid or solid (appearance can vary based on purity and conditions)
Boiling Point Data may vary, but generally in a range related to its molecular structure and intermolecular forces
Melting Point Specific value depends on its crystalline structure and purity
Density Density value is characteristic of this compound and related to its mass - volume relationship
Solubility Solubility in common organic solvents like dichloromethane, chloroform, etc., but limited in water
Vapor Pressure Depends on temperature and is related to its volatility
Refractive Index Has a specific refractive index value that can be measured
Flash Point Flash point indicates flammability potential

As an accredited 4-Bromo-2,3-Difluoroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - bromo - 2,3 - difluoroiodobenzene packaged in a sealed glass bottle.
Storage 4 - bromo - 2,3 - difluoroiodobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and oxidizing agents. It should be kept in a tightly sealed container, preferably made of a material resistant to corrosion. Due to its potential reactivity and toxicity, storage areas should be restricted to trained personnel only.
Shipping 4 - bromo - 2,3 - difluoroiodobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict chemical shipping regulations, ensuring secure transit to prevent any leakage or damage during transportation.
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4-Bromo-2,3-Difluoroiodobenzene 4-Bromo-2,3-Difluoroiodobenzene
General Information
Historical Development
4 - Bromo - 2, 3 - Difluoroiodobenzene is also a chemical product. At the beginning, the craftsman studies the secret of chemical technology, and wants to make this new product. The initial design, the heavy production, the matching of raw materials, and the control of the heat are not easy. However, people do not work, but they do not work. It takes a long time to get the method.
The method is good, and the quantity is also increased. The field of work, the use, or the raw materials of the material, or the help of the material. From the past production, to the present widespread use, the development of this compound is a big step in the field of chemical technology.
Product Overview
4-Bromo-2,3-difluoroiodobenzene is an organic compound. It may be a colorless to pale yellow liquid with special chemical properties.
In this compound, bromine (Br), fluorine (F) and iodine (I) coexist, giving it unique reactivity. Bromine atoms can participate in nucleophilic substitution reactions. Fluorine atoms can affect the electron cloud distribution of molecules due to their high electronegativity, which changes the chemical stability and reaction selectivity of compounds. Iodine atoms can be used as leaving groups or participate in bonding reactions under specific reaction conditions.
In the field of organic synthesis, 4-bromo-2,3-difluoroiodobenzene is often an important intermediate. Due to its unique structure, it can construct complex organic molecular structures through various chemical reactions, providing key starting materials for research in many fields such as medicinal chemistry and materials science, and has high research and application value.
Physical & Chemical Properties
4-Bromo-2,3-Difluoroiodobenzene is an important compound in organic synthesis. Its physical and chemical properties are unique and have certain stability. Looking at its physical properties, it is a colorless to slightly yellow liquid at room temperature, with a specific boiling point and melting point, and a specific density. This is due to the influence of bromine, fluorine and iodine atoms in the molecular structure. Its chemical properties are active. Due to the presence of halogen atoms on the benzene ring, it is prone to nucleophilic substitution reactions, which can react with many nucleophilic reagents to form new organic compounds. And because it contains different halogen atoms, the reactivity and selectivity vary. This compound is widely used in the field of organic synthesis and provides an important structural unit for the construction of complex organic molecules.
Technical Specifications & Labeling
Today there is a product called 4 - Bromo - 2,3 - Difluoroiodobenzene. Its production method needs to follow the technical specifications and identification (commodity parameters). To make this product, the method of fine research should be used to check the properties of its raw materials and control the degree of reaction.
The ratio of raw materials must be accurate, such as halogenation reaction, the amount of bromine and fluorine is related to the purity of the product. The reaction conditions are also the key. The temperature and the length of time can all affect its formation.
The identification of the product lists the parameters in detail, which are related to the purity and the amount of impurities. This is the proof of quality. According to this technical specification and strict adherence to the identification parameters, we can obtain this excellent product and demonstrate its effectiveness in the field of chemical industry.
Preparation Method
To prepare 4-Bromo-2,3-Difluoroiodobenzene, the raw materials and production process, reaction steps and catalytic mechanism are crucial. First, take an appropriate amount of o-difluorobenzene, place it in a clean reactor, add a brominating reagent, catalyze with a specific catalyst, control the temperature and reaction time, so that the bromine atom precisely replaces the specific hydrogen atom on the benzene ring to obtain bromoo-difluorobenzene.
Then, transfer this product to another reaction device, add an iodine substitution reagent, adjust the reaction conditions, so that the iodine atom is also successfully connected to the benzene ring, and then form the target product 4-Bromo-2,3-Difluoroiodobenzene. The whole process requires strict control of the conditions of each reaction step, accurate allocation of raw material proportions, and extremely high requirements for catalyst activity and selectivity in order to ensure the purity and yield of the product.
Chemical Reactions & Modifications
4 - Bromo - 2,3 - Difluoroiodobenzene is an important compound in organic synthesis. In chemical research, its chemical reaction and modification have attracted much attention.
The synthesis of this compound in the past may have severe reaction conditions and low yield. For example, the traditional halogenation reaction in the early stage requires high temperature, strong alkali and other conditions, and there are many side reactions, and the product separation is complicated.
Today, researchers are committed to optimizing its chemical reaction. With the use of new catalysts, the reaction can be carried out under milder conditions. For example, a new type of metal complex catalyst can effectively reduce the activation energy of the reaction, improve the reaction selectivity, and increase the yield significantly.
In terms of modification, 4-Bromo-2,3-Difluoroiodobenzene can be given new properties by introducing specific functional groups. Such as connecting nitrogen-containing heterocycles, its electron transport properties can be enhanced, and it may have extraordinary applications in the field of organic optoelectronic materials. In this way, continuous exploration of chemical reactions and modifications can make it shine in more fields.
Synonyms & Product Names
4-Bromo-2,3-difluoroiodobenzene is also a genus of chemical substances. Its synonyms and trade names are important marks in academia and industry. Scholars from the ancient times have their own methods for studying physical properties and marking famous objects. Today, 4-bromo-2,3-difluoroiodobenzene also has many nicknames, all of which explain its characteristics and are used in various ways.
In the field of chemistry, there are many people who have the same thing but different names. This 4-bromo-2,3-difluoroiodobenzene, its synonyms are either due to the order of discovery, or due to the different emphasis on structural analysis. As for the trade name, it is related to the promotion of production and sales, so as to make it simple and easy to understand, so as to recognize its excellence and facilitate its circulation.
All kinds of different names and trade names are bridges for communication between academia and industry. Scholars use them to distinguish physical properties, and workers use them for their actions. Although the names are different, they all refer to this thing, such as the return of all rivers to the sea, the same way, to help the progress of chemistry, and the prosperity of industry.
Safety & Operational Standards
4 - Bromo - 2,3 - Difluoroiodobenzene Safety and Operating Specifications
Husband 4 - Bromo - 2,3 - Difluoroiodobenzene, a common product for chemical research. Its special nature is related to safety and operating standards, and must not be ignored.
Safety matters, the first protection. When touching this object, you must wear appropriate protective clothing, such as chemical-resistant clothing, to protect the body and skin; wear protective gloves to prevent it from touching your hands and causing injury; wear protective goggles to prevent it from splashing into your eyes and damaging your eyes. This is a priority for your own safety.
When storing, keep it in a cool, dry and well-ventilated place. Keep away from fire and heat sources, because it may be flammable, it is dangerous in case of fire. It must also be placed separately from oxidizing agents, acids, etc., to prevent adverse reactions and cause disasters.
When operating, it should be carried out in a fume hood. This is to remove harmful gases from escaping and ensure the safety of the operating environment. Be careful and handle it with care to avoid leakage caused by damage to the container. If it is unfortunate to leak, take immediate measures. Small leaks can be absorbed by inert materials such as sand and vermiculite and collected in suitable containers. If there are large leaks, they must be built embankments or dug for containment, and transferred to a tank or a special collector by pump, recycled or transported to a waste treatment site for disposal.
Furthermore, operators should be professionally trained to be familiar with the properties, hazards and emergency treatment methods of this substance. If you accidentally come into contact with the skin, you should immediately remove the contaminated clothing and rinse with plenty of running water. If it enters the eye, lift the eyelids, rinse with running water or normal saline, and seek medical attention in time.
In short, the safety and operating standards of 4 - Bromo - 2,3 - Difluoroiodobenzene must be observed carefully to ensure the smooth progress of the research and the well-being of the caregivers.
Application Area
Today there is a product called 4 - Bromo - 2,3 - Difluoroiodobenzene. This product is quite wonderfully used in various application fields.
In the field of pharmaceutical research and development, it can be used as a key intermediate. Due to the properties of halogen atoms, molecules can precisely fit with biological targets, helping to create new special drugs and cure various diseases.
In the field of materials science, it participates in the synthesis of special functional materials. It can be chemically modified to give materials unique optoelectronic properties for high-end electronic devices, such as advanced display screens and high-efficiency photovoltaic modules, to improve their performance and efficiency.
Furthermore, in the fine chemical industry, this compound is also an important cornerstone. Through delicate reaction paths, it is transformed into a variety of high-value-added fine chemicals, adding bricks and mortar to the chemical industry, expanding industrial boundaries, and promoting related industries to move forward vigorously.
Research & Development
Today there is a product named 4 - Bromo - 2,3 - Difluoroiodobenzene. We are exploring its research and development as a researcher. The structure of this product is unique, and the atoms of bromine, fluorine and iodine are co-structured into its form, and the chemical properties are different, which attracts the attention of the academic community.
In the experimental research, its reactivity and selectivity are the focus of research. After various attempts, the reaction behavior of it under different conditions is observed to clarify its optimal reaction path, hoping to improve the yield and purity.
Looking forward to its development, if it can make good use of its characteristics, there may be breakthroughs in the fields of medicine, materials and so on. Based on it, synthesizing new drugs or developing materials with special properties are all promising directions. The road to scientific research is long, but we uphold the heart of exploration and hope to explore new paths for its development and achieve great results.
Toxicity Research
Today there is a product, named 4 - Bromo - 2,3 - Difluoroiodobenzene. As a chemical researcher, I am very concerned about its toxicity research.
The toxicity of this product is a threat to everyone's safety. To observe its properties in detail, multiple experiments are required. Or take various organisms and observe their reactions after exposure to this product, observe their physiological changes and behavioral differences. Explore its impact on the body from the cellular level to see if it damages cellular structure and disrupts cellular metabolism.
Also think about its diffusion in the environment, if it flows into water sources and soil, what will be the disturbance to the surrounding ecology. Therefore, toxicity research is not only to show the harm to individual organisms, but also to protect the stability of the ecology and ensure the safety of all living beings. It must be treated strictly and there must be no slack.
Future Prospects
I have tried to research chemical products, and recently focused on 4 - Bromo - 2,3 - Difluoroiodobenzene. This material has extraordinary potential and has broad development prospects in the future. In the field of organic synthesis, it may pave the way for the development of new materials. I expect that in time, with the unique properties of this compound, materials with excellent performance can be produced for use in electronics, medicine and many other fields. In the future, it is expected to break through the limitations of existing technologies, achieve more efficient synthesis, reduce costs and benefit related industries. When the technology is mature, its application will be like a bright star, illuminating the way forward in many fields and laying a solid foundation for future development. This is my vision for its future.
Where to Buy 4-Bromo-2,3-Difluoroiodobenzene in China?
As a trusted 4-Bromo-2,3-Difluoroiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Bromo-2,3-Difluoroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 4-Bromo-2, 3-Difluoroiodobenzene?
4-Bromo-2,3-difluoroiodobenzene, a genus of organohalogenated aromatic hydrocarbons. Its chemical properties are interesting, including its rich in bromine, fluorine and iodine halogen atoms in the molecule, each with unique reactivity.
Bromine atoms in this compound exhibit the typical properties of halogenated hydrocarbons. When encountering nucleophiles, nucleophilic substitution reactions can occur. In an alkaline environment, nucleophiles such as hydroxyl anions (OH) can interact with the carbon site where the bromine atom is located, and the bromine ions leave, thereby generating corresponding alcohol derivatives. This reaction mechanism is based on the attack of nucleophilic agents on positively charged carbon nuclei, following the SN1 or SN2 reaction path, depending on the reaction conditions and substrate structure.
Fluorine atoms, due to their high electronegativity, endow molecules with unique electronic effects. It reduces the electron cloud density of the benzene ring and increases the difficulty of electrophilic substitution reactions on the benzene ring. However, the presence of fluorine atoms can also enhance the stability and lipid solubility of the molecule, which has a great impact on the physical and chemical properties of the compound. In some specific reactions, fluorine atoms can act as locators, affecting the position of other substituents entering the benzene ring.
Although iodine atoms are relatively active, they can participate in various reactions under specific conditions. For example, the coupling reaction can occur under metal catalysis, and it can be combined with other organohalides or organometallic reagents to form more complex organic molecular structures. This reaction is an important means of building carbon-carbon bonds in the field of organic synthesis, and is of great significance for the creation of new organic materials, drug molecules, etc.
In addition, the benzene ring structure of the compound also gives it aromatic properties, making it have certain thermal and chemical stability. However, due to the substitution of halogen atoms, the distribution of benzene ring electron clouds changes, resulting in different reactivity compared with benzene. In many organic reactions, 4-bromo-2,3-difluoroiodobenzene, as an important intermediate, provides rich possibilities for the synthesis of various organic compounds by virtue of the characteristics of each halogen atom, and occupies an important position in the field of organic synthetic chemistry.
What are the main uses of 4-Bromo-2, 3-Difluoroiodobenzene?
4-Bromo-2,3-difluoroiodobenzene is also an important intermediate commonly used in organic synthesis. Its main uses cover the following ends.
In the field of medicinal chemistry, this compound is often a key building block. Because it contains halogen atoms, it can introduce various active groups by means of nucleophilic substitution and other reactions to build drug molecules with diverse structures. For example, when developing antibacterial and antiviral drugs, this can be used as a starting material, modified by a series of reactions, or lead compounds with specific biological activities can be obtained, and then optimized into clinically usable drugs.
In materials science, 4-bromo-2,3-difluoroiodobenzene also has extraordinary uses. Using it as a raw material, polymer materials with special optoelectronic properties can be prepared by polymerization and other means. Such materials may be applied to organic Light Emitting Diodes (OLEDs), solar cells and other fields. Due to the existence of halogen atoms, they can adjust the electron cloud distribution of materials, improve charge transport properties, and enhance the overall properties of materials.
In the field of organic synthesis chemistry, it is often the cornerstone of building complex organic molecules. Through classic organic reactions such as palladium-catalyzed cross-coupling reactions, it can be coupled with different organometallic reagents to increase carbon chains or build carbon rings and heterocyclic structures. Chemists can use this to expand the complexity of molecules and achieve the synthesis of target products, providing powerful tools for the study of total synthesis of natural products.
In addition, in the field of pesticide chemistry, with this compound as the starting point, modified and modified, new high-efficiency and low-toxicity pesticides may be developed. By introducing specific groups, its biological activity and mechanism of action can be adjusted to meet the needs of modern agriculture for pesticides.
What is the synthesis method of 4-Bromo-2, 3-Difluoroiodobenzene?
To prepare 4-bromo-2,3-difluoroiodobenzene, you can follow the following method. First take a suitable benzene derivative as the starting material. This raw material needs to contain a substitutable group, and its position is related to the position of bromine, fluorine and iodine atoms in the target product.
In the first step, bromine atoms can be introduced by electrophilic substitution reaction. Here, the raw materials can be placed in a system containing brominated reagents, such as bromine and suitable catalysts, such as iron tribromide. Under suitable temperature and reaction conditions, bromine atoms will selectively replace hydrogen atoms at specific positions on the benzene ring to obtain bromine-containing benzene derivatives.
In the second step, fluorine atoms are introduced. This can be achieved by nucleophilic substitution reaction. Select a suitable fluorination reagent, such as potassium fluoride, and match it with a phase transfer catalyst to improve the reaction efficiency. Under specific solvent and temperature conditions, the fluoride ion in the fluorinated reagent will replace other groups at specific positions on the benzene ring to form a benzene derivative containing bromine and fluorine.
At the end, iodine atoms are introduced. Iodizing reagents, such as cuprous iodide, can be used in the presence of suitable ligands and bases, through nucleophilic substitution or other related reactions, so that iodine atoms replace the groups at the target position, and finally 4-bromo-2,3-difluoroiodobenzene can be obtained.
During the reaction process, the reaction conditions, such as temperature, reaction time, and reagent dosage, need to be carefully controlled to increase the yield and purity of the target product. After each step of the reaction, the product should be purified by methods such as column chromatography and recrystallization to remove impurities and provide pure raw materials for the next step. In this way, following this series of steps and conditions, 4-bromo-2,3-difluoroiodobenzene can be obtained.
4-Bromo-2, 3-Difluoroiodobenzene What should I pay attention to when storing and transporting?
4-Bromo-2,3-difluoroiodobenzene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
The first word storage, because of its active nature, is quite sensitive to environmental conditions. When placed in a cool, dry and well-ventilated place, do not expose to high temperature or humidity. High temperature can easily accelerate its chemical reaction, or cause decomposition and deterioration; humid environment may cause it to react with water vapor, which will damage its quality. It must be sealed and stored to prevent contact with oxygen, carbon dioxide and other substances in the air. This compound may oxidize with oxygen, changing its chemical structure and affecting its performance.
As for transportation, it is also necessary to be cautious. It must be operated in accordance with the relevant regulations on the transportation of hazardous chemicals. Due to its toxicity, corrosiveness or other dangerous characteristics, the transportation container must be strong and well sealed to prevent leakage. During transportation, avoid violent vibration and collision to prevent damage to the container. At the same time, the transportation personnel should be familiar with its dangerous characteristics and emergency treatment methods. In case of emergencies, they can respond in time and properly to ensure the safety of transportation. In short, the storage and transportation of 4-bromo-2,3-difluoroiodobenzene must strictly follow the relevant specifications, and attach great importance to environmental conditions and operation details to ensure its quality and transportation safety.
What is the market price of 4-Bromo-2,3-Difluoroiodobenzene?
I look at your question, and I am inquiring about the market price of 4-bromo-2,3-difluoroiodobenzene. However, the price of this chemical often changes due to many factors, and it is difficult to determine an exact value.
First, the trend of supply and demand determines its price. If there are many people who want it, but the supply is small, the price will increase; conversely, if the supply exceeds demand, the price will be reduced. Second, the cost of production is also the key. The price of raw materials, the method of preparation, the cost of energy consumption, etc., all affect its cost, which in turn affects the selling price. Third, the quality is also related to the price. Those with high purity and excellent quality are often more expensive than those with ordinary quality. Fourth, the state of market competition cannot be ignored. If there are many merchants and the competition is fierce, the price may be lower; if there are few suppliers and they have the potential to monopolize, the price may be higher.
In addition, geographical differences, purchase quantities, etc., also have an impact on the price. In prosperous cities, prices may vary due to factors such as logistics and operating costs; bulk purchasers can often get preferential prices.
To sum up, in order to know the exact market price of 4-bromo-2,3-difluoroiodobenzene, it is necessary to carefully observe market dynamics, consult suppliers, and comprehensively consider multi-channel information to obtain a more accurate price.