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4-Bromo-1-Iodo-2-(Trifluoromethyl)Benzene

4-Bromo-1-Iodo-2-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    916047

    Name 4-Bromo-1-Iodo-2-(Trifluoromethyl)Benzene
    Molecular Formula C7H3BrF3I
    Molecular Weight 360.903 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 224 - 226 °C
    Melting Point N/A
    Density 2.193 g/cm³
    Solubility Insoluble in water, soluble in organic solvents like dichloromethane
    Flash Point 99.4 °C
    Purity Typically high - purity (e.g., 97%+ in commercial products)
    Cas Number 124646-66-4

    As an accredited 4-Bromo-1-Iodo-2-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4 - bromo - 1 - iodo - 2 - (trifluoromethyl)benzene in sealed chemical - grade bottle.
    Storage 4 - bromo - 1 - iodo - 2 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials like glass, to prevent leakage and exposure to air or moisture, which could potentially cause degradation.
    Shipping 4 - bromo - 1 - iodo - 2 - (trifluoromethyl)benzene is shipped in well - sealed, corrosion - resistant containers. Special care is taken to prevent physical damage and ensure compliance with chemical transportation regulations due to its nature.
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    4-Bromo-1-Iodo-2-(Trifluoromethyl)Benzene 4-Bromo-1-Iodo-2-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    Wenfu 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene This product originated from the research of various chemical sages. At the beginning, many people were groping for the method of synthesis. At that time, the skills were not refined, and if they wanted to make this product, they often encountered obstacles.
    However, all the masters are determined, and they have been working hard for many years. Looking back at the past, every time there is a new method to try, or because the materials are difficult to find, or because the heat is not suitable, the results are rare. However, everyone is not discouraged, and with perseverance, they explore the details.
    Gradually, the techniques are improving day by day. Everyone has insight into the reaction conditions and the ratio of materials. Finally, this product can be prepared in a relatively stable way. Since its initial appearance, up to now, this compound has been used in the fields of medicine and materials, and it is the unremitting work of many people.
    Product Overview
    4-Bromo-1-iodine-2- (trifluoromethyl) benzene is also an organic compound. It may be a colorless to pale yellow liquid with special chemical properties. This compound is widely used in the field of organic synthesis.
    In its molecular structure, the presence of bromine, iodine and trifluoromethyl gives it unique reactivity. Bromine atoms can participate in nucleophilic substitution reactions, while iodine atoms play a key role in some coupling reactions. The strong electron-absorbing properties of trifluoromethyl affect the electron cloud distribution of molecules, thereby changing their reaction tendency.
    Preparation of this compound often requires delicate chemical methods and specific reaction steps to achieve high purity products. In practical applications, it can be used as an important intermediate for the synthesis of complex drug molecules and functional materials, contributing to the development of chemical research and industrial production.
    Physical & Chemical Properties
    4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene is an organic compound, and its physicochemical properties are crucial. Looking at its physical properties, at room temperature, this substance is mostly solid, with a specific melting point and boiling point. The melting point is about [X] ° C, and the boiling point is up to [X] ° C. Because its molecular structure contains bromine, iodine and trifluoromethyl, it has a high density.
    When it comes to chemical properties, bromine and iodine atoms in this compound are highly active and easily participate in substitution reactions. In nucleophilic substitution reactions, bromine and iodine atoms can be replaced by other nucleophilic reagents. Trifluoromethyl has strong electron absorption, which affects the distribution of electron cloud of benzene ring, reduces the density of electron cloud of adjacent and para-site of benzene ring, and increases the relative of meta-site, which in turn affects its electrophilic substitution reaction activity. Usually, meta-site is more prone to electrophilic substitution. These physicochemical properties lay the foundation for its application in the field of organic synthesis.
    Technical Specifications & Labeling
    Today there is a product called 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene. To clarify its technical specifications and identification (commodity parameters), it is necessary to study its characteristics in detail. The production of this product requires a fine method, from the selection of raw materials to the control of reactions. Its color state, purity, and amount of impurities are all key technical specifications. The color should be pure and correct, the purity should be high, and the impurities must be minimal. The key to marking is to specify its name and mark its key parameters, such as molecular weight, structural formula, etc., so that those who see it can know its properties. According to this specification, the quality of this product can be guaranteed, which is beneficial to the user, and the industry can be trusted.
    Preparation Method
    4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene is an important compound in organic synthesis. The preparation method and the selection of raw materials are very important. Compounds containing bromine, iodine and trifluoromethyl can be selected as starting materials.
    The reaction steps are as follows: First, a specific bromine-containing compound and an iodine-containing reagent are used to precisely locate and combine bromine and iodine atoms under suitable reaction conditions. This process requires temperature control and the selection of a suitable catalyst to make the reaction proceed in the desired direction. Subsequently, trifluoromethyl is introduced, and a specific trifluoromethyl-containing reagent can be used to access it through a specific reaction mechanism.
    In terms of production process, the reaction equipment is very strict, and corrosion resistance is required to deal with fluorinated reagents. And the separation and purification after each step of the reaction is also critical. Chromatography, recrystallization and other methods can be used to ensure the purity of the product. In this way, high purity 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene can be obtained.
    Chemical Reactions & Modifications
    In recent years, the chemical substance, 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene, was studied in detail. The way of chemical reaction is related to the change of halogenation. The benzene ring of bromine, iodine and trifluoromethyl may have nucleophilic substitution in time. Nucleophilic reagents are nearby, or easy bromine and iodine, because the electron of the benzene ring is different, and the activity of halogen atoms is special.
    As for the change, the genus of temperature and solvent are involved. Raising temperature often promotes the reaction rate; the polarity of the solvent is different, which also leads to the change of reaction and speed. Polar solvents or nucleophilic substitution, because it can stabilize intermediates.
    My generation studied it, and hoped to clarify its rationale and transformation law, so as to improve this transformation, increase the purity and rate of yield, contribute to chemical industry, and lay the foundation for other research and application.
    Synonyms & Product Names
    Today there is a thing called 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene. Although its name is complex, it is of great importance to our chemical researchers. The synonyms of this thing are actually the key clues to explore its characteristics and uses.
    Synonyms are named either according to their structural characteristics or their reaction characteristics. Although the names are different, they all refer to this thing. And its trade name also shows a unique logo when it is in market circulation and application.
    In our research, we can study the synonyms and trade names in detail to clarify the application and cognition of this thing in different fields and scenarios. Due to regional differences or industry habits, the title has changed. However, in essence, they are all the same chemical substance. Only by having a deep understanding of its synonyms and trade names can we integrate them in research, production and application, and use them properly to contribute to the development of chemistry and the progress of science and technology.
    Safety & Operational Standards
    4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene Safety and Operating Specifications
    If you want to make 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene products, the first priority is safety, and you must follow the operating specifications to be safe.
    This product is chemically active or potentially harmful. When operating, be in a well-ventilated place to prevent air from accumulating and prevent accidents. Operators must wear protective equipment, such as goggles, gloves, protective clothing, etc., to protect their eyes from eye damage, protect their hands from poison, and protect their clothes from skin damage.
    When taking it, the method should be stable and accurate. Measure it with a clean appliance and do not spill it. If there is any accidental sprinkling, clean it up quickly according to the procedures. Sprinkle on the countertop, cover it with a moisture-absorbing material, collect it and discard it in the designated place, and then wash the countertop to remove its residue.
    When storing, choose a cool and dry place, away from fire and heat sources. Seal the device to prevent it from evaporation and deliquescence. The logo is clear, and the name of the product, characteristics, hazards, etc. are written for easy identification.
    If you accidentally touch it during operation, rinse it with plenty of water as soon as possible. If it touches the skin, rinse it for medical treatment; if it enters the eyes, it is especially necessary to rush and seek medical treatment quickly. If you inhale the gas, leave the scene quickly and go to a well-ventilated place. If you are unwell, you need to seek medical attention.
    In short, the products made of 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene are safe, standardized operation, and always keep in mind to ensure people's safety and well-being.
    Application Area
    4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene is also a chemical material. It can be used in the field of research and development, or it can be used as a starting material for special effects. With its unique properties, it may be able to create new solutions and solve the pain of diseases.
    It is also useful for material science. Or special materials can be added to improve the novelty of materials, such as additive materials, to change their performance and resistance, so that the materials can be used in high-tech tools.
    It is also used in research and development, or in good quality. Its chemical properties, the control of bacteria, the health of crops, and the protection of harvests. In addition, this object is used in many fields, and it is all huge. It will be well used by those who study it.
    Research & Development
    In recent years, more than in the exploration of chemical products, especially 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene. Its unique nature, in the way of organic synthesis, has great potential.
    At the beginning of the study of its preparation method, through various attempts, through the selection of reagents and the adjustment of conditions. Or the temperature, or the amount of agent, are all carefully investigated. Start to get a better method, the yield gradually increases, and the quality is also purified.
    Then explore its application. In the creation of drugs, it can be used as a key intermediate to assist the structure of active molecules. In the development of materials, it can also add its specific properties. Looking at its prospects, it is like the first light of morning, shining brightly.
    We should continue to study it, explore its new uses, and improve its production methods. Hope this product is used in the field of chemical industry, and it has an extraordinary effect. It has made great contributions to both academia and industry, so as to promote the progress of chemistry and benefit the prosperity of people's lives.
    Toxicity Research
    If you taste the things in the world, those who are harmful must not be ignored. Today there is a thing named 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene. For our chemical researchers, the study of its toxicity is crucial.
    The properties of this thing may contain bromine, iodine, trifluoromethyl and other groups. Bromine and iodine are genera, or have active properties, and trifluoromethyl is also unusual. Its toxicity may enter the body and disturb the order of physiology. Or hurt the internal organs, disrupt the flow of qi and blood; or damage the meridians and collaterals, hinder the communication of nerves.
    In fact, it is necessary to use a rigorous method to observe its response to various environments and organisms. Observe whether it changes or not in water and soil, and observe how it affects the bodies of insects and rats. It is necessary to seek true evidence, to clarify the depth of its poison, and to provide evidence for the world to avoid harm and use things, so as to live up to the responsibility of research.
    Future Prospects
    Fu 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene is also a chemical substance. Our research, the strength of its performance, has not yet been developed, full of expectations.
    This physical property is special, or can be used in new research. Today's research, seeking special effects, and this compound may be able to affect its performance. With its characteristics, it may be able to act on lesions and reduce the suffering of patients.
    And in the field of materials, it can also be used. It may be possible to improve the properties of materials to make them more resistant to corrosion and more resistant, and it is more important to use in aviation, electronics, etc.
    We must do our best to explore in depth. It is hoped that the method of science will be used to clarify its secrets, so that it can be used by people to benefit the world, and to work with the macros that have not yet been achieved.
    Where to Buy 4-Bromo-1-Iodo-2-(Trifluoromethyl)Benzene in China?
    As a trusted 4-Bromo-1-Iodo-2-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-1-Iodo-2-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 4-Bromo-1-Iodo-2- (Trifluoromethyl) Benzene?
    4-Bromo-1-iodine-2- (trifluoromethyl) benzene is one of the organic compounds. Its chemical properties are particularly important and are widely used in the field of organic synthesis.
    In this compound, bromine, iodine and trifluoromethyl are all key functional groups. Bromine and iodine atoms give molecules unique reactivity due to their electronegativity and atomic radius. Bromine atoms are slightly smaller than iodine atoms and slightly more electronegativity. Both can participate in nucleophilic substitution reactions. Under appropriate conditions, bromine and iodine atoms can be replaced by various nucleophilic reagents, thereby introducing diverse functional groups and expanding the structure and function of molecules.
    The presence of trifluoromethyl has a great impact on the properties of this compound. Trifluoromethyl has a high electronegativity and strong electron-withdrawing effect, which can significantly change the electron cloud density of the benzene ring, reduce the electron cloud density of the adjacent and para-sites of the benzene ring, and therefore affect the electrophilic substitution reaction activity on the benzene ring. Usually, electrophilic reagents tend to attack the meso-sites. And the introduction of trifluoromethyl can greatly improve the lipid solubility, stability and biological activity of the compound, which is of great significance in the fields of pharmaceutical chemistry and materials science.
    In addition, in 4-bromo-1-iodine-2 - (trifluoromethyl) benzene molecules, the conjugated system of the benzene ring also contributes The conjugated system confers certain stability to the molecule and can affect the optical and electrical properties of the molecule. This conjugated structure may play a key role in the study of photochemical reactions or electron transport materials. It can also be used as an important intermediate for the synthesis of complex organic molecules, through a series of organic reactions, to construct more complex and unique compounds.
    What are the main uses of 4-Bromo-1-Iodo-2- (Trifluoromethyl) Benzene?
    4-Bromo-1-iodine-2 - (trifluoromethyl) benzene is also an organic compound. It has a wide range of uses and plays a great role in the field of organic synthesis.
    First, it can be used as an intermediary for pharmaceutical synthesis. The development of medicinal chemistry relies on many organic compounds as raw materials. The special structure of this compound allows it to participate in specific reactions and build a framework for complex pharmaceutical molecules. With the activity of halogen atoms and trifluoromethyl atoms, chemists can ingeniously design reaction pathways to synthesize molecules with specific pharmacological activities, such as the development of new antimicrobial and anticancer drugs, which are of great help to human health.
    Second, it also has important applications in materials science. Because of its fluorine atoms, it gives the material unique properties. If introduced into polymer materials, it can improve the weather resistance, chemical stability and surface properties of the material. It can be used to prepare high-performance coatings and plastics, so that they still have good performance in harsh environments, prolong the service life of materials, and have broad application prospects in aerospace, automobile manufacturing and other industries.
    Third, it is indispensable in pesticide synthesis. The existence of halogen atoms and trifluoromethyl gives it a certain biological activity. On this basis, high-efficiency, low-toxicity and environmentally friendly pesticides can be developed, which is helpful for pest control in agricultural production, improve crop yield and quality, and ensure food security.
    In conclusion, 4-bromo-1-iodine-2 - (trifluoromethyl) benzene has a variety of uses due to its unique structure, and plays an important role in the fields of medicine, materials, and agriculture, promoting the development and progress of various industries.
    What are the synthesis methods of 4-Bromo-1-Iodo-2- (Trifluoromethyl) Benzene?
    The synthesis methods of 4-bromo-1-iodine-2-trifluoromethyl-benzene are quite diverse. The common method is to use benzene derivatives containing trifluoromethyl as the starting material and undergo halogenation reaction.
    First, 2- (trifluoromethyl) aniline can be used as the starting material. First, it is diazotized with sodium nitrite and hydrobromic acid to form a diazonium salt. Subsequently, potassium iodide is added, and the diazo group is replaced by iodine to obtain 1-iodine-2- (trifluoromethyl) benzene. This product is then brominated with bromine in the presence of suitable catalysts such as iron powder or iron tribromide. Due to the localization effect of substituents on the benzene ring, bromine atoms will be mainly substituted at specific positions to produce 4-bromo-1-iodine-2- (trifluoromethyl) benzene.
    Second, 2- (trifluoromethyl) benzoic acid is used as the starting material. It is first converted into the corresponding acid chloride, and then reduced to give 2- (trifluoromethyl) benzaldehyde. Then, through haloform reaction, halogen atoms can be introduced. For example, with sodium hypobromite, bromine atoms can be introduced at specific positions in the benzene ring. Subsequent to a suitable iodization reaction, the target product can be synthesized.
    Alternatively, 1-bromo-2- (trifluoromethyl) benzene is used as a raw material. By selecting a specific iodizing agent, such as iodine elemental substance and suitable oxidizing agent, under appropriate reaction conditions, such as the presence of suitable solvents, temperatures and catalysts, iodine atoms can be introduced into the benzene ring to obtain 4-bromo-1-iodine-2- (trifluoromethyl) benzene. These methods have their own advantages and disadvantages, and should be selected according to actual needs and conditions.
    What are the precautions for 4-Bromo-1-Iodo-2- (Trifluoromethyl) Benzene during storage and transportation?
    4-Bromo-1-iodine-2 - (trifluoromethyl) benzene must be paid attention to during storage and transportation.
    This substance has certain chemical activity. When stored, the first environment is dry. Because of its exposure to water or water vapor, or chemical reactions such as hydrolysis, the quality is damaged. The humidity of the warehouse should be controlled at a low level, such as relative humidity not exceeding 60%.
    Temperature is also critical. It should be stored in a cool place to avoid hot topics. Due to high temperature or its volatilization, it may accelerate and even cause decomposition reactions. It is recommended that the storage temperature be between 2-8 ° C.
    Furthermore, the packaging must be tight. It should be packed in glass bottles or special plastic bottles to ensure that it is well sealed to prevent air and water vapor from infiltrating.
    During transportation, it is extremely important to prevent shock and collision. Because it is a fragile bottled chemical, bumps and collisions may cause packaging to break and materials to leak. The transportation vehicle must drive smoothly, and when the road is bumpy, it should pass slowly.
    At the same time, it should be protected from direct sunlight. Light may cause photochemical reactions to change the chemical structure and properties. Vehicles should be equipped with shading facilities, such as tarpaulins, etc., and the transportation period should also be selected when the light is weak in the morning and evening.
    In addition, transportation and storage personnel need professional training, familiar with the properties of the chemical and emergency treatment methods. In the event of an accident such as a leak, it can respond promptly and correctly to ensure the safety of personnel and the environment from contamination.
    What is the market price range for 4-Bromo-1-Iodo-2- (Trifluoromethyl) Benzene?
    I look at the "4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) Benzene" you are inquiring about, which is an organic compound. Its market price range is difficult to determine, due to the interaction of many factors.
    First, the cost of raw materials has a great impact. The price of bromide, iodide and trifluoromethyl-containing raw materials required for the preparation of this compound fluctuates erratically. If raw materials are scarce or production is difficult, the price will rise; conversely, if raw materials are abundant, the price may drop.
    Second, the simplicity of the preparation process also affects its price. If delicate and complex synthesis steps are required, such as multi-step reactions, harsh reaction conditions, such as high temperature, high pressure, special catalysts, etc., the cost will increase and the price will also be high; if the process is simple and efficient, the cost may be reduced, and the price will also be lower.
    Third, the market supply and demand situation is the key. If many industries, such as medicine, material science, etc., have strong demand for it, but the supply is limited, the price will be high; if the demand is weak and the supply is excessive, the price will easily fall.
    Fourth, the product purity requirements are also related to the price. High-purity products are difficult to prepare, the cost is high, and the price is naturally expensive; ordinary purity products, the price may be relatively low.
    Combined with various factors, the price of this compound may range from tens to hundreds of yuan per gram, but this is only a rough estimate. The actual price should be carefully investigated according to specific market conditions, transaction quantity and quality.