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4-Bromo-1-Iodo-2-(Trifluoromethoxy)Benzene

4-Bromo-1-Iodo-2-(Trifluoromethoxy)Benzene

Hongda Chemical

    Specifications

    HS Code

    890329

    Chemical Formula C7H3BrF3IO
    Molecular Weight 357.90
    Appearance Solid (likely, based on similar compounds)
    Solubility In Water Low (non - polar groups dominate)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Stability Stable under normal conditions, but reactive towards strong nucleophiles and reducing agents

    As an accredited 4-Bromo-1-Iodo-2-(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - bromo - 1 - iodo - 2 - (trifluoromethoxy)benzene in a sealed, labeled bottle.
    Storage 4 - bromo - 1 - iodo - 2 - (trifluoromethoxy)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent exposure to air and moisture. Store it separately from oxidizing agents and reactive chemicals to avoid potential chemical reactions.
    Shipping 4 - bromo - 1 - iodo - 2 - (trifluoromethoxy)benzene is shipped in well - sealed, corrosion - resistant containers. Shipment adheres to strict chemical transport regulations, ensuring safe transit to prevent any leakage or hazard.
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    4-Bromo-1-Iodo-2-(Trifluoromethoxy)Benzene 4-Bromo-1-Iodo-2-(Trifluoromethoxy)Benzene
    General Information
    Historical Development
    4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene is also a special product of chemical products. Its origin originated in the research and exploration of the chemical industry. The first time, it exists in the field of reason, and the human heart tries its best to make it into a product.
    In the month, how many clever and ingenious ways to think about it. The first is to make a new work, to get the clue of synthesis. Or in the room, set the like, and consider the quality of the parts, the degree and strength.
    With the light of the work, the synthesis is becoming more and more exquisite. The initial is crude, to the refinement of the work, every step is condensed before the effort. This kind of chemical object exists spontaneously, from the abundance to the complexity, in the river of transformation, it is the unique value, and it explores new frontiers in multiple fields, which is also a shining pearl in the history of chemical research.
    Product Overview
    Description of 4-Bromo-1-iodine-2 - (trifluoromethoxy) benzene
    There is a product called 4-bromo-1-iodine-2 - (trifluoromethoxy) benzene. It is an organic halide with a delicate structure. Bromine, iodine and trifluoromethoxy are arranged in an orderly manner on the benzene ring.
    This product has unique properties. It is a colorless to slightly yellow liquid at room temperature. If it is pure, it is translucent and clear. However, its gas is pungent, and the smell can sense the unique taste of halogenates. Its melting point has a fixed number, and the boiling point is suitable for a specific temperature, so that the separation and purification can be precisely controlled.
    Discuss the use, in the field of organic synthesis, it is the most important intermediate. It can introduce various functional groups through various reactions to build complex organic molecules. In pharmaceutical chemistry, or involved in the development of new drugs; in materials science, or laying the foundation for the creation of special functional materials.
    The way of synthesis requires specific chemical methods, selection of suitable reagents and conditions, and steps such as halogenation and etherification to strictly control the reaction process before high-purity products can be prepared.
    Physical & Chemical Properties
    4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene is an organic compound. In terms of physical properties, it is mostly solid at room temperature, and it has a certain melting point and boiling point due to factors such as intermolecular forces. From the chemical properties, bromine and iodine have high atomic activity and are prone to nucleophilic substitution reactions. Under appropriate conditions, they can be replaced by other nucleophilic reagents, resulting in a variety of compounds. The existence of trifluoromethoxy gives the substance unique chemical activity and stability. Because of its strong electronegativity, it affects the distribution of molecular electron clouds and changes the check point of reactivity. This compound has great potential in the field of organic synthesis and can be used as a key intermediate to build complex organic structures through various reactions, providing basic materials for new drug development, materials science and many other fields.
    Technical Specifications & Labeling
    4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene is an important raw material for organic synthesis. Its technical specifications and labeling (product parameters) are related to the accuracy and effectiveness of synthesis. Looking at its technical specifications, the purity must reach a very high standard, and the impurity content must be strictly controlled to ensure a smooth reaction. The color and characteristics must also meet specific requirements to prove its quality.
    In terms of labeling, the name must be accurate and clearly marked to prevent confusion. The packaging label should also be complete, with express safety precautions to protect the user's completeness. As for product parameters, such as melting point, boiling point and other physical parameters, they need to be accurately determined to provide a reliable basis for subsequent applications. In this way, 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene can play its best role in the field of chemical synthesis.
    Preparation Method
    To prepare 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene, the raw materials are crucial to the production process, reaction steps and catalytic mechanism.
    The raw material is based on bromine, iodine and trifluoromethoxy-related compounds. The reaction starts by mixing the bromine-containing compound and the iodine-containing reagent in a suitable solvent according to a specific ratio. The solvent needs to have good solubility to the reactants and does not conflict with the reaction system. The temperature is raised to a certain range, and the initial reaction between the two is prompted to form a halogenated intermediate.
    Then, the trifluoromethoxy-containing reagent is introduced to adjust the reaction temperature and pH, and optimize the reaction environment. With the help of a specific catalyst, the substitution process of trifluoromethoxy can be accelerated, which can reduce the activation energy of the reaction, improve the reaction rate and yield.
    During the reaction process, the degree of reaction at each stage is closely monitored, and the reaction node is controlled by modern analytical methods, such as chromatography and spectroscopy. After the reaction is complete, a series of post-processing processes, such as extraction, purification, and crystallization, are used to obtain pure 4-Bromo-1-Iodo-2 - (Trifluoromethoxy) Benzene products to ensure that their quality and purity meet the expected standards.
    Chemical Reactions & Modifications
    The industry of chemical industry is related to the change of all things, the transformation of substances, and the subtlety. In today's words, 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene, the chemical reaction and modification of this compound have a lot to study.
    Looking at the reaction, the halogenation reaction may be the key. The substitution of bromine and iodine has its own rules and varies according to the reaction conditions. Such as temperature and the genus of solvent, it can affect the direction of the reaction. When the temperature is high, it may promote the speed of the reaction, but it may also be disturbed by side reactions.
    As for the modification, the introduction of fluoroalkoxy groups makes this compound unique. The distribution of its electron cloud changes, causing its chemical activity to change. Or in the nucleophilic substitution, it shows a different state, which can add a new way to organic synthesis.
    The beauty of chemistry lies in finding the rules of reaction and exploring the changes of substances. In 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene, when its reaction and modification are deeply studied, it is the responsibility of our generation of chemical researchers to realize the new environment of chemical industry and use it for later generations.
    Synonyms & Product Names
    4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene is an important chemical substance. Its synonym and trade name are of great significance in the field of our chemical research.
    This substance, with its unique chemical structure, exhibits specific properties in many chemical reactions. Its synonym depends on the characteristics of its chemical composition or the relevant details of its discovery process. The trade name is often closely related to the marketing strategy and product positioning of the manufacturer.
    In the past research, many scholars have discussed the synonym and trade name of this substance. Due to different names, the dissemination and communication of research results may be affected. Only by accurately clarifying its synonyms and trade names can we ensure correct academic exchanges and orderly production and application.
    In the process of current chemical research, the continuous attention and research on the synonyms and trade names of 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene must be a key link in promoting the development of this field.
    Safety & Operational Standards
    4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene Safety and Operation Specifications
    Husband 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene is a research and development thing. If you want to get it safely and use it well, you must have its own rules.
    #1. Store
    This product should be placed in a cool, dry and well-connected place. Avoid direct sunlight, and do not approach fire or oil sources. Because of its nature or because of it, or cause danger. And Oxidation,,,,, If the phase is mixed, it is feared that the strong will be reversed, and the damage will be immediate.
    #2. Methods of operation
    In operation, it is necessary to wear appropriate anti-damage clothing, such as anti-damage clothing, gloves, etc. Also wear a mask to prevent this object from entering the eye and causing the eye to be affected. In the place of operation, it is necessary to pass the mask, so that the mask can be obtained and dispersed, so as not to gather in the air and prevent people from breathing.
    If you take this thing, use a dry and dry utensil, and do not let it overflow. Use a seal, that is, seal its container and set it in place.
    #3. For urgent measures
    , quickly wash the skin with a large amount of water, and then wash it with soap. If it enters the eye, immediately use physiological water or water to wash it, and it is necessary to wash it quickly. If you inhale it, you can quickly go to a fresh place. If you are sleepy, you can apply oxygen inhalation, and you can also seek emergency treatment.
    Therefore, in the safe operation of 4-Bromo-1-Iodo-2- (Trifluoromethoxy) Benzene, you must not be careless, in order to ensure people's safety and safety, and the things you seek can be carried out.
    Application Area
    4-Bromo-1-Iodo-2- (Trifluoromethoxy) Benzene is a unique organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drug molecules with specific biological activities. Due to the unique structure of bromine, iodine and trifluoromethoxy in the molecule, it can effectively regulate the interaction between drugs and targets and improve drug efficacy. In the field of materials science, with its special chemical structure, it can participate in the creation of new functional materials, such as optoelectronic device materials. Its structure gives materials unique optoelectronic properties, or can improve the efficiency and stability of optoelectronic devices. In the field of organic synthetic chemistry, in order to build an important building block of complex organic molecules, various chemical reactions can be used to synthesize organic compounds with diverse structures, greatly expanding the boundaries of organic synthesis, which is of great significance in many scientific research and industrial production fields.
    Research & Development
    In recent years, I have focused on the research of 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene. This compound has unique properties and has potential applications in various fields.
    Initially, I investigated its molecular structure in detail, analyzed its bonding mode and electron cloud distribution, in order to clarify its chemical activity source. Then, explore its synthesis method. After many attempts, various reagents and conditions were prepared, and finally the best path was obtained. Although the process was difficult and encountered many problems, such as the reaction yield did not meet expectations and the side reactions were complicated, I did not give up.
    Every time there is a setback, I will review the plan, consult the classics, and ask my colleagues for advice. Improve the reaction process and optimize conditions, such as temperature control, pH adjustment, etc. After unremitting efforts, the synthesis method has gradually matured, and the yield has also steadily increased.
    Today, this achievement is gradually dawning. 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene's synthesis technology is expected to help the transformation of related industries, and develop its talents in the fields of medicine and materials. I will continue to study it to promote its wider application and deeper development.
    Toxicity Research
    The toxicity of 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene was studied. This substance has a unique structure and contains groups such as bromine, iodine and trifluoromethoxy. After various experiments, it may be harmful to organisms under specific environments.
    The mice were fed with food containing this substance as an experiment. After a while, the mice behaved differently, or appeared tired or ate less. And their organs also changed, and the liver and kidney function indicators showed abnormalities.
    In cell experiments, cells were cultured in a solution containing this substance, and cell growth was hindered, proliferation was slowed down, and some cell morphologies were distorted. From this point of view, 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene has certain toxicity. Follow-up studies should study its toxicological mechanism and prevention and control strategies in detail to avoid its harm to life and the environment in production and application.
    Future Prospects
    I look at the chemical industry of the world, new products are emerging one after another, and they are changing with each passing day. Today, I am talking about 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethoxy) Benzene, which is quite promising in the future.
    This compound has a unique structure and unique properties, and must be important in various fields. In pharmaceutical chemistry, it may become the basis for the development of new agents, cure various diseases, and save people and patients. In material science, special materials can be made to meet the needs of high-end, such as aerospace and electronic devices, so that their performance is outstanding.
    And technology is advancing rapidly, and exploration is not endless. In the future, we will be able to improve the synthesis method, reduce its cost and increase its yield. Or in the new use to open up, unlimited possibilities. Although there may be thorns in the road ahead, but I believe it will shine, for the progress of the world, add bricks and tiles, and create a brilliant future.
    Where to Buy 4-Bromo-1-Iodo-2-(Trifluoromethoxy)Benzene in China?
    As a trusted 4-Bromo-1-Iodo-2-(Trifluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-1-Iodo-2-(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Bromo-1-Iodo-2- (Trifluoromethoxy) Benzene?
    4-Bromo-1-iodine-2 - (trifluoromethoxy) benzene is also an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
    Gein has a unique molecular structure and contains functional groups such as bromine, iodine and trifluoromethoxy. These functional groups endow the compound with diverse reactivity and can participate in many organic reactions.
    In pharmaceutical chemistry, it can be used to construct molecular structures with specific biological activities. Drug developers often use their unique structures to introduce target molecules to modify the physicochemical properties of drugs, such as improving solubility, enhancing bioavailability, and enhancing interaction with targets, in the hope of creating more efficient and safe drugs.
    In the field of materials science, it also has important uses. It can be used as a building block for building functional materials and participate in the synthesis of materials with special optical, electrical or thermal properties. For example, in the preparation of organic optoelectronic materials, through rational design and reaction, it can be integrated into the material skeleton, or the electronic transport properties and fluorescence emission characteristics of materials can be adjusted to meet the specific requirements of material properties in fields such as organic Light Emitting Diodes (OLEDs) and solar cells.
    Furthermore, in the field of fine chemicals, it is also an important raw material for the preparation of special chemicals. After various chemical reactions, a series of high-value-added fine chemicals can be derived, which are used in flavors, dyes, additives and other industries, providing key support for the development of related industries.
    What are the synthesis methods of 4-Bromo-1-Iodo-2- (Trifluoromethoxy) Benzene?
    The synthesis of 4-bromo-1-iodine-2- (trifluoromethoxy) benzene depends on the technology of organic synthesis. In the past, although the method of organic synthesis was complex, it has laid the foundation for today's research.
    First, it can be started by the benzene ring containing a specific substituent. First, bromine atoms are introduced into the benzene ring with an appropriate reagent. This step requires fine control of the reaction conditions, such as temperature, reactant ratio, and catalyst dosage. Because the selectivity of the bromination reaction is related to the purity and yield of the subsequent product. Commonly used brominating reagents, such as bromine combined with an appropriate catalyst, can make bromine atoms fall precisely at the designated position of the benzene ring in a suitable solvent.
    Then, trifluoromethoxy is introduced. This process may require special reagents and reaction environments. Reagents containing trifluoromethoxy can be used to connect trifluoromethoxy to the benzene ring through nucleophilic substitution and other reactions. This step also needs to pay attention to the regulation of reaction conditions to prevent side reactions. Such as the polarity of the solvent, the strength of the base, etc., all have a great impact on the reaction process.
    As for the introduction of iodine atoms, iodine substitutes can be used at appropriate stages, and the iodine atoms can be connected to the target position by suitable reaction mechanisms, such as variants of halogenation reactions. The iodine substitution reaction also requires attention to many factors, such as the stability of the reactive intermediates, the pH of the reaction system, etc.
    After each step of the reaction, it is often necessary to go through the process of separation and purification to obtain a pure product. Available methods, such as column chromatography, recrystallization, etc. Column chromatography separates according to the polarity of the substance, and recrystallization purifies by different solubility. After many operations and careful regulation, 4-bromo-1-iodine-2 - (trifluoromethoxy) benzene can be obtained. This synthesis method requires a good understanding of the organic reaction mechanism and meticulous operation.
    What are the physical properties of 4-Bromo-1-Iodo-2- (Trifluoromethoxy) Benzene?
    4-Bromo-1-iodine-2 - (trifluoromethoxy) benzene, this is an organic compound, its physical properties are quite unique, and it is of great significance in the field of chemistry.
    Looking at its physical state, under normal temperature and pressure, 4-bromo-1-iodine-2 - (trifluoromethoxy) benzene is often in a liquid state. Because of its molecular structure, bromine, iodine and trifluoromethoxy groups endow molecules with specific polarity and spatial structure, resulting in moderate intermolecular forces, so this state exists.
    When it comes to melting point, due to the interaction between atoms and groups, the melting point of this compound is relatively low. Bromine and iodine atoms have large atomic radius and mass, which can increase the intermolecular dispersion force. However, the strong electron-absorbing property of trifluoromethoxy group weakens the tight accumulation between molecules to a certain extent, and the final melting point is not high.
    In terms of boiling point, due to the large relative mass of the molecule and the existence of polar groups, the intermolecular force is strong, and its boiling point is relatively high. Bromine and iodine atoms increase the molecular mass, and trifluoromethoxy enhances the molecular polarity, so that in addition to the dispersion force, there is a strong dipole-dipole force between molecules. More energy is required to overcome the intermolecular attractive force and realize gas-liquid conversion, so the boiling point is higher.
    Solubility is also a key physical property. This compound is insoluble in water because its molecules are non-polar as a whole. Water is a polar solvent. According to the principle of "similarity and miscibility", 4-bromo-1-iodine-2 - (trifluoromethoxy) benzene with weak polarity interacts with polar water molecules to dissolve. However, it is soluble in many organic solvents, such as dichloromethane, chloroform, ether, etc. Such organic solvents have certain polarity or weak polarity, and can interact with the compound molecules through dispersion force, dipole-dipole force, etc., so that they are mutually soluble.
    In addition, the color state of 4-bromo-1-iodine-2- (trifluoromethoxy) benzene, when pure or colorless to light yellow transparent liquid, may vary slightly in appearance due to impurities or storage conditions. Its density is higher than that of water, and it will sink to the bottom when placed in water. Because its molecules contain heavy atoms such as bromine and iodine, the unit volume mass increases, so the density is higher than that of water.
    What are the chemical properties of 4-Bromo-1-Iodo-2- (Trifluoromethoxy) Benzene?
    4-Bromo-1-iodine-2 - (trifluoromethoxy) benzene, this is an organic compound. Its chemical properties are interesting and worth exploring in detail.
    Let's talk about its halogen atom properties first. The compound contains two halogen atoms, bromine (Br) and iodine (I). Bromine atoms are highly active and can often emerge in nucleophilic substitution reactions. When encountering nucleophilic reagents, bromine atoms are easily replaced. For example, in an alkaline environment, nucleophilic reagents can attack carbon atoms attached to bromine and replace bromine to form new organic compounds. Although iodine atoms are slightly more stable than bromine atoms, they can also participate in the reaction under certain conditions. For example, in some metal-catalyzed reaction systems, iodine atoms can form intermediates with metals, which can then promote the reaction and participate in the construction of complex organic molecular structures.
    Then look at the group of trifluoromethoxy (-OCF
    ). Trifluoromethoxy has strong electron absorption and can significantly affect the electron cloud density of the benzene ring. Due to its strong electron absorption effect, the electron cloud density on the benzene ring decreases, especially the electron cloud density of ortho and para-sites decreases more significantly. As a result, in the electrophilic substitution reaction, the reactivity of the compound is very different from that of ordinary benzene ring derivatives. Electrophilic reagents tend to attack the intersites with relatively high electron cloud density. In addition, the presence of trifluoromethoxy also affects the physical properties of the molecule, such as it can enhance the fat solubility of the compound and make it more soluble in organic solvents, which is of great significance for its applications in organic synthesis and drug research and development.
    In addition, the atoms and groups in the compound interact with each other. The electronic effect of halogen atoms and trifluoromethoxy groups interacts to shape the reactivity and selectivity of the molecule as a whole. In some reactions, it is necessary to comprehensively consider their synergy to achieve the desired reaction results. For example, in multi-step organic synthesis, clever use of the characteristics of these atoms and groups can achieve the precise construction of complex organic molecules.
    What is the price range of 4-Bromo-1-Iodo-2- (Trifluoromethoxy) Benzene in the market?
    4-Bromo-1-iodine-2 - (trifluoromethoxy) benzene, the price of this product in the market varies for many reasons, and it is difficult to determine its exact number.
    First, the source of the material is different, and the price is different. If the source is wide and easy to obtain, the price may be slightly cheaper; if the source is rare and difficult to find, the price will be high. Second, the preparation method also has an impact. If the process is simple and efficient, the cost may decrease, and the price will follow; if the method is complex and the consumption is huge, the price will be high. Third, the supply and demand of the city is also the main reason. If there are many applicants and there are few suppliers, the price will rise; if the supply exceeds the demand, the price will decline.
    In the past, the price of this substance in the market was between tens and hundreds of yuan per gram. However, this is only an approximate number, not an exact value. If there is a special time, if the material is tight and the preparation changes, the price will fluctuate greatly. To know the exact price, when consulting the chemical material supplier in detail, you can get the real-time price to meet the needs.