4-Bromo-1-Fluoro-2-Methoxybenzene

Hongda Chemical

Specifications

HS Code	647511
Chemical Formula	C7H6BrFO
Molecular Weight	205.02
Appearance	Colorless to light yellow liquid
Boiling Point	196 - 198 °C
Density	1.567 g/cm³
Flash Point	83 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Stability	Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 4-Bromo-1-Fluoro-2-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 4 - bromo - 1 - fluoro - 2 - methoxybenzene packaged in a sealed glass bottle.
Storage	Store 4 - bromo - 1 - fluoro - 2 - methoxybenzene in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Use a tightly sealed container, preferably made of glass or a suitable plastic, to prevent leakage and evaporation. Label the storage container clearly to avoid confusion.
Shipping	4 - bromo - 1 - fluoro - 2 - methoxybenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling and secure packaging to prevent leakage during transit.

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General Information

Historical Development

Wenfu 4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene There is also a reason for its popularity. In the past, the chemists worked diligently in the field of organic synthesis, hoping to obtain new things to expand the boundaries of chemistry.
At the beginning, everyone was thirsty for knowledge and explored the wonders of material changes. After years of hard work and careful investigation in various reactions, there was an inkling of the preparation of this compound.
At that time, although the equipment was not as sophisticated as it is today, the public relied on their determination and repeated trials with limited materials. Or adjust the temperature, or change the amount of reagents, or change the reaction time. After countless setbacks, they were not discouraged.
Finally, 4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene is here. Since its birth, it has added a weapon to organic synthesis, and has been used in medicine, materials and other industries. Later generations continue to explore more of its mysteries to promote the prosperity of the chemical industry.

Product Overview

4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene is also an organic compound. It is a colorless to light yellow liquid with a special odor. The structure of this compound is that bromine atoms, fluorine atoms and methoxy groups are respectively connected to specific positions in the benzene ring. The introduction of bromine gives it specific chemical activity and can be used in many reactions such as nucleophilic substitution. The presence of fluorine atoms enhances molecular stability and hydrophobicity. Methoxy groups affect the distribution of its electron cloud, change the electron cloud density of the benzene ring, and affect the reaction activity and selectivity. In the field of organic synthesis, it is often used as an intermediate and can be converted into key structural fragments of various drugs and materials through multi-step reactions. It is widely used in the fields of medicinal chemistry and materials science and is an important cornerstone of organic synthesis.

Physical & Chemical Properties

4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene is also an organic compound. Its physical and chemical properties are quite important to scholars. Looking at its physical properties, it is at room temperature, or in a liquid state, with a special smell. Its boiling point, melting point, etc. are all fixed, which is related to the structure and interaction of its molecules. Regarding its chemical properties, it has special activity because it contains functional groups such as bromine, fluorine, and methoxy. Bromine atoms can participate in nucleophilic substitution reactions, fluorine atoms affect the distribution of electron clouds in molecules, and methoxy groups also change the activity of benzene rings. In the field of organic synthesis, it has a wide range of uses, or is a key intermediate, participating in the preparation of various complex compounds. Scholars often study it to clarify its properties and make good use of it, which contributes greatly to the development of chemistry.

Technical Specifications & Labeling

4-Bromo-1-fluoro-2-methoxybenzene is also an organic compound. Looking at the preparation technique, it is necessary to follow the precise method. First take an appropriate amount of raw materials, and the ratio of the materials is the key to the process. When the raw materials meet, in a specific reaction vessel, control the appropriate temperature and pressure. If the temperature is too high or low, it will affect the quality and quantity of the product. The same is true for pressure, and if it is not appropriate, the reaction will be abnormal.
When the reaction is completed, the process needs to be carefully observed and monitored with fine instruments. After the reaction is completed, the purification of the product should not be ignored. Use various separation methods, such as distillation and extraction, to remove its impurities and obtain a pure product.
The label of the product should specify its chemical structure, purity geometry, and label its physical properties, such as color, taste, melting point, etc. In this way, it is suitable for the standard 4-bromo-1-fluoro-2-methoxybenzene, which can meet the needs of scientific research and industry.

Preparation Method

To prepare 4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene, the raw materials, production process, reaction steps and catalytic mechanism are as follows.
First take an appropriate amount of 1 - Fluoro - 2 - Methoxybenzene as the starting material, which is the basis of the reaction. Using iron bromide as the catalyst, at a suitable temperature, the liquid bromine is slowly dripped into the reaction vessel. The catalysis of iron bromide can polarize the bromine molecule and enhance its reactivity. This is the electrophilic substitution reaction step. Bromine positive ions attack the benzene ring and replace hydrogen atoms.
During the reaction process, it is necessary to precisely regulate the temperature and liquid bromine droplet acceleration to prevent the formation of polybromination by-products. After the reaction is completed, the product is extracted with organic solvent, and then purified by distillation, recrystallization and other means.
This preparation method, with the catalytic power of iron bromide, makes the reaction efficient, and the operation is relatively simple. It can obtain 4-Bromo-1-Fluoro-2-Methoxybenzene with high purity.

Chemical Reactions & Modifications

Wenfu 4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene is related to chemical reactions and modifications. I thought about it very much, so I studied it carefully.
The chemical reaction of husband is really the cardinal of material changes. In this compound, its bromine, fluorine, and methoxy groups are all active check points for the reaction. Bromine, a halogen element, has the property of nucleophilic substitution, and can interact with many nucleophilic reagents to introduce new groups on the benzene ring to modify the properties of this compound. Although fluorine atoms are small, they are highly electronegative, which can affect the distribution of electron clouds in molecules, thereby changing their physical and chemical properties. Methoxy is rich in electrons, which can stabilize the positive charge of benzene ring and affect the orientation of the reaction.
As for the modification method, nucleophilic substitution, electrophilic substitution and other reactions can be used. Take nucleophilic substitution as an example, choose an appropriate nucleophilic reagent, interact with 4-Bromo-1-Fluoro-2-Methoxybenzene, or obtain a product with better performance, which can be used in medicine, materials and other fields. This is what chemical researchers should think deeply and study diligently.

Synonyms & Product Names

4-Bromo-1-fluoro-2-methoxybenzene, this substance is of great significance in my chemical research. Its synonym and trade name are also important for our investigation.
I have heard of the ancient chemical experts, and they have their own exquisite names for substances. 4-Bromo-1-fluoro-2-methoxybenzene, or another name, to meet different uses. The synonym here depends on its structure, characteristics, or the rules set by predecessors.
As for the trade name, merchants use it as the basis, introduce new ones, and title it to honor the characteristics and attract attention. Or because of its wide range of uses, it can be used in various fields of pharmaceuticals and materials, so the trade names show their own strengths.
Now I will study this thing in detail, and the distinction between the alias and the trade name can be used in the academic and business circles. Although it is only 200 words, the mystery of it will be further investigated by us. To clarify the full picture of the alias of 4-bromo-1-fluoro-2-methoxybenzene and the trade name will add to the chemical research.

Safety & Operational Standards

4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene is an important chemical synthesis raw material and has a wide range of applications in many fields. To use this product safely and in a standardized manner, specific safety and operating practices must be strictly followed.
First of all, when storing it, it should be placed in a cool, dry and well-ventilated place. This compound is sensitive to light and heat, so it is necessary to avoid direct sunlight and high temperature environments. Storage containers should also be well sealed to prevent it from evaporating or reacting with components in the air. For example, if stored at too high a temperature, it may cause its chemical properties to change and affect the subsequent use effect.
During operation, be sure to take personal protective measures. The experimenter should wear appropriate protective clothing, gloves and protective glasses to prevent direct contact between the skin and the eyes. Because of its toxicity, if you accidentally touch the skin, you should immediately rinse with a large amount of water and seek medical treatment in time; if it splashes into the eyes, you need to rinse quickly with a large amount of water and seek professional medical help as soon as possible.
Furthermore, when using this compound for chemical reactions, it is necessary to operate under suitable reaction conditions according to the reaction characteristics. Precise control of reaction temperature, time and proportion of reactants to ensure that the reaction is carried out safely and efficiently. For example, in a certain type of reaction, excessive temperature may cause side reactions, which not only reduce the purity of the product, but also may pose a safety risk.
In addition, after use, the remaining 4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene and related waste should be properly disposed of in accordance with relevant regulations. It must not be discarded at will to avoid pollution to the environment. Waste needs to be collected in a specific container and handled by a professional treatment agency to ensure environmental safety.
In conclusion, the safety and operation regulations for 4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene cover storage, personal protection, reaction operations, and waste disposal. Only strict compliance can ensure the safety of personnel, ensure the smooth conduct of experiments, and protect the environment.

Application Area

4-Bromo-1-fluoro-2-methoxybenzene is also an organic compound. Its application field is quite broad. In the field of medicinal chemistry, it can be used as an intermediate to help synthesize special drugs and treat human diseases. Such as some analgesic agents, with their structural characteristics, to relieve pain.
In materials science, it is also useful. Or can participate in the preparation of materials with special properties, such as those with unique optoelectronic properties, for electronic devices to increase their performance and make the equipment more sophisticated.
In the fragrance industry, due to its special chemical structure, it may provide unique raw materials for the synthesis of fragrances, resulting in a unique aroma and adding fragrance to the world. All of these are seen in the importance of 4-bromo-1-fluoro-2-methoxybenzene in various application fields.

Research & Development

In recent years, Yu has dedicated himself to the research of the organic compound 4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene. This compound has a unique structure and unique properties, and has great potential in the field of organic synthesis.
Initially, explore its synthesis path. After repeated experiments, refer to various ancient methods and techniques, and finally obtain a feasible method. Starting with specific halogenated aromatics, supplemented by exquisite reaction conditions, gradually build its unique structure. During the reaction process, the temperature and catalyst dosage need to be precisely controlled, and if there is a slight difference, it will fall short.
Then, study its properties in detail. Observe its physical properties, such as melting point, solubility, etc., to clarify its state in different environments. It also explores its chemical activity, reacts with various reagents, observes its changes, and analyzes its mechanism.
Looking to the future, we hope to expand the research and development of new organic materials based on this compound. Or used to create efficient electronic devices, or to help make breakthroughs in drug synthesis. Ji Neng uses the research findings to contribute to the development of chemistry and make achievements.

Toxicity Research

Wenfu 4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene is a substance that must be noticed by those who take toxicology research as their service. Although its properties are not widely known, it is also an important issue in our field of research.
Chemical substances cover the toxicity behind the appearance. 4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene contains bromine, fluorine, and methoxy groups, and has a unique structure. Bromine may cause chemical reactions in living organisms, disturbing their normal physiological functions; fluorine has high activity, easy to combine with other substances, or cause cell damage; methoxy may also participate in metabolism, toxic side effects.
At present, the confirmation of its toxicity still depends on precise experiments. It is necessary to use cell models to explore its effects on cell proliferation and apoptosis, and to observe its effects on organs and systems in animal experiments. Only through such rigorous research can we know the depth of its toxicity. When the world uses this substance, it can be used for safety, avoiding its harm and promoting its benefits, so as to achieve a good environment for chemical research.

Future Prospects

I try to study this 4 - Bromo - 1 - Fluoro - 2 - Methoxybenzene. Its development in the future is quite impressive. The chemical properties of this substance are unique, and it may open up new paths in the development of medicine. Looking at the current needs of medicine, there are many difficult diseases. If this substance is used as a basis to explore its pharmacology, it may be able to make miraculous drugs and save people from diseases.
And it also has potential in the field of materials science. It can be used in subtle ways to change its characteristics and make new materials, which can be used in electronic equipment, aerospace and other fields. With the advance of future science and technology, with each passing day, this object may become a key thing, helping science and technology to make great strides forward. Although there may be thorns in the road ahead, we scientific researchers should be fearless and brave enough to explore the unknown, hoping to use this thing to contribute to future development and create brilliant achievements.

Where to Buy 4-Bromo-1-Fluoro-2-Methoxybenzene in China?

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Frequently Asked Questions

As a leading 4-Bromo-1-Fluoro-2-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-Bromo-1-Fluoro-2-Methoxybenzene?

4-Bromo-1-fluoro-2-methoxybenzene, which is widely used in the field of organic synthesis.
First, it can be used as a pharmaceutical intermediate. When creating new drugs, its unique molecular structure can be introduced into drug molecules through specific chemical reactions, which has a key impact on drug activity, selectivity and pharmacokinetic properties. For example, in the development of some antibacterial drugs or drugs for the treatment of neurological diseases, it is used to build the core structure to optimize drug performance.
Second, it also has important applications in the field of materials science. Because it contains halogen atoms and methoxy groups, it can participate in the preparation of functional materials, such as organic optoelectronic materials. In the synthesis of organic Light Emitting Diode (OLED) or organic solar cell materials, it can be used as a basic raw material to impart unique photoelectric properties to the material through chemical modification and structural adjustment, such as adjusting the energy gap of the material, improving the carrier mobility, etc., so as to improve the performance of the material in the field of optoelectronics.
Third, it is also indispensable in pesticide synthesis. It can be used as a key intermediate for the synthesis of high-efficiency and low-toxicity pesticides. By reacting with other chemical substances, pesticides with specific biological activities are created to control crop diseases and insect pests and ensure the yield and quality of agricultural production. For example, insecticides with high selective poisoning effect against specific pests can be synthesized, or fungicides with good control effect on certain plant diseases can be synthesized.
In summary, 4-bromo-1-fluoro-2-methoxybenzene plays an important role in many fields such as medicine, materials, and pesticides due to its special chemical structure, providing a key foundation for technological innovation and Product Research & Development in many fields.

What are 4-Bromo-1-Fluoro-2-Methoxybenzene synthesis methods?

There are several common methods for synthesizing 4-bromo-1-fluoro-2-methoxybenzene.
First, 2-methoxy-4-bromophenol is used as the starting material. This phenolic compound is first reacted with halogenated alkanes under basic conditions. For example, potassium carbonate is used as a base. In a suitable organic solvent, the hydrocarbon group of the halogenated alkane replaces the hydrogen of the phenolic hydroxyl group to form an ether bond, and then the target product is obtained. This reaction condition is mild and the operation is relatively simple. However, the acquisition of the starting material may require certain steps.
Second, 1-fluoro-2-methoxybenzene is used as the substrate. Bromine atoms are introduced through bromination reaction. Bromine can be selected as a brominating reagent and reacted in the presence of an appropriate catalyst. If iron powder or iron tribromide is used as the catalyst, bromine and benzene ring undergo electrophilic substitution reaction, and bromine atoms are selectively introduced at specific positions. Controlling reaction conditions, such as temperature and reagent dosage, is crucial to improve the yield and selectivity of the target product. The raw materials for this method are relatively easy to find, but the selective control of bromination reaction requires fine operation.
Third, the benzene ring containing a suitable substituent can also be used as the starting material, and the target molecule can be gradually constructed through a multi-step reaction. For example, the methoxy group is introduced first, which can be reacted with the corresponding phenol and halomethane under basic conditions; then the fluorine atom and the bromine atom are introduced. The fluorine atom can be introduced through a specific nucleophilic substitution reaction, and the bromine atom is introduced in a bromination reaction as described above. Although this approach has many steps, it is more flexible and can be adjusted according to the availability of raw materials and the convenience of reaction conditions.
There are various methods for synthesizing 4-bromo-1-fluoro-2-methoxybenzene, each with its own advantages and disadvantages. The best one should be selected according to the actual situation, such as raw material cost, reaction conditions, yield and selectivity requirements.

What are the physical properties of 4-Bromo-1-Fluoro-2-Methoxybenzene?

4-Bromo-1-fluoro-2-methoxybenzene is one of the organic compounds. Its physical properties are quite worthy of investigation.
Looking at its properties, under normal temperature and pressure, it is mostly a colorless to light yellow liquid. In this state, it has good fluidity, is easy to pour and transfer, and is easy to use in many chemical operations.
When it comes to boiling point, it is about within a certain temperature range. The boiling point is also the critical temperature at which a substance changes from liquid to gas. The boiling point of 4-bromo-1-fluoro-2-methoxybenzene is such that at a specific temperature, the molecule is energized enough to break free from the liquid phase and turn into a gas phase. This boiling point characteristic can be used when separating and purifying the compound. By distillation, it can be separated from the mixture according to the difference in boiling points.
As for the melting point, it is also an important physical property. The melting point is the temperature at which a substance changes from a solid state to a liquid state. The melting point of 4-bromo-1-fluoro-2-methoxybenzene determines its physical state at a specific temperature environment. If the temperature is lower than the melting point, it is in a solid state and the structure is relatively stable; if it is higher than the melting point, it gradually melts into a liquid state.
Its density also has a fixed number. The density of this compound is also the mass of the substance per unit volume. The density of this compound makes it float on the upper layer or sink on the bottom due to density differences when mixed with other liquids. This property can be used as a basis for judgment in liquid-liquid separation operations.
In terms of solubility, 4-bromo-1-fluoro-2-methoxy benzene has a certain solubility in organic solvents such as ethanol and ether. This is because the molecular structure of this compound is similar to that of organic solvents due to the principle of similarity dissolution, so it can be mixed with each other. However, the solubility in water is not good, because the polarity of the molecule is quite different from that of water, and it is not easy to blend with each other.
The physical properties of 4-bromo-1-fluoro-2-methoxybenzene are of great significance in chemical synthesis, analytical testing, and related chemical production, providing a basis for its application and treatment.

What is the chemistry of 4-Bromo-1-Fluoro-2-Methoxybenzene?

4-Bromo-1-fluoro-2-methoxybenzene, this is an organic compound. Its chemical properties are unique and contain many characteristics.
First of all, from the perspective of halogen atoms, the bromine and fluorine atoms in the molecule endow them with certain activity. Bromine atoms are relatively large, and the electron cloud is easily affected by the outside world. In the nucleophilic substitution reaction, it is easy to be attacked by nucleophiles, so that substitution occurs to form new compounds. For example, in the case of hydroxyl-containing nucleophiles, bromine atoms can be replaced by hydroxyl groups to generate corresponding phenolic derivatives. This process requires suitable reaction conditions, such as suitable bases and solvents, to promote the smooth progress of the reaction.
Although the fluorine atom is small, it has a strong electronegativity, which has a great influence on the electron cloud density distribution of the benzene ring. It can reduce the electron cloud density of the benzene ring ortho-para, resulting in the electrophilic substitution reaction, the electrophilic reagent is more inclined to attack the meso-site. However, due to the presence of methoxy groups, the situation is more complicated.
The methoxy group is the power supply substitution group, which can increase the electron cloud density of the benzene ring, and mainly increases the electron cloud density of the ortho-para-site, and has an activation effect on the electrophilic substitution reaction. In the electrophilic substitution reaction, the electronic effects of the methoxy group and the fluorine atom compete with each other. Usually, the power supply of the methoxy group is more However, the electron-absorbing induction effect of the fluorine atom cannot be ignored, and sometimes it has a subtle impact on the choice of the reaction check point.
In addition, in this compound, the carbon-oxygen bond of the methoxy group is relatively stable, but under certain conditions, such as in a strongly acidic environment, the ether bond may break. In case of hydrohalic acid, under heating conditions, the methoxy group may be replaced by the halogen atom to form halobenzene derivatives.
In summary, the chemical properties of 4-bromo-1-fluoro-2-methoxybenzene are rich and diverse, and the interaction between halogen atoms and methoxy groups determines its performance in various chemical reactions, providing many possible reaction paths and products for the field of organic synthesis.

What is the price range of 4-Bromo-1-Fluoro-2-Methoxybenzene in the market?

4-Bromo-1-fluoro-2-methoxybenzene is in the market, and its price is difficult to determine. The price of this product often varies due to various reasons, and it cannot be generalized.
First, the source of the material is the main reason. If the origin is abundant and the supply is plentiful, the price may be flat; if the supply is thin and there are many people seeking it, the price will rise. If the ore veins in other places are abundant, the price of the company that produces this material should be cheaper than elsewhere.
Second, the difficulty of preparation also affects its price. If you need a complicated method to make this product, use expensive agents, and consume a huge amount of labor, the cost will be high and the price will be high. On the contrary, if the preparation technique is simple, the required materials are easy to obtain and inexpensive, and the price will also drop.
Third, the supply and demand of the city have a particular impact. If a certain industry is booming, the demand for this product will increase greatly, and the supply will not meet the demand, and the price will rise; if the demand is low and the supply exceeds the demand, the price will decline.
In the "Tiangong Kaiwu", although the price of 4-bromo-1-fluoro-2-methoxybenzene is not detailed, the production and market conditions of the product can be used for reference. In today's world, the market conditions are various. To determine its price, you should consult the experts of chemical materials, the brokers of the city, or carefully examine the market market reports to obtain its near-real price. Or on the platform of chemical trading, looking at its listing price, you can also know the approximate price. However, this price is not constant, and the price changes with time.