Hongda Chemical
Products
Home  /  Products  / 

4-Bromo-1-Difluoromethyl-2-Fluorobenzene

4-Bromo-1-Difluoromethyl-2-Fluorobenzene

Hongda Chemical

    Specifications

    HS Code

    347441

    Chemical Formula C7H5BrF3
    Molar Mass 225.01 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point Approximately 180 - 185 °C
    Density Around 1.6 - 1.7 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Flash Point Approximately 70 - 80 °C
    Vapor Pressure Low vapor pressure at room temperature

    As an accredited 4-Bromo-1-Difluoromethyl-2-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram vial of 4 - bromo - 1 - difluoromethyl - 2 - fluorobenzene, well - sealed for safety.
    Storage 4 - bromo - 1 - difluoromethyl - 2 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames to prevent ignition. Keep it in a tightly sealed container to avoid vapor leakage. Store it separately from oxidizing agents and reactive chemicals to prevent dangerous reactions. Ensure the storage area is clearly labeled for easy identification.
    Shipping 4 - bromo - 1 - difluoromethyl - 2 - fluorobenzene is shipped in accordance with strict chemical regulations. Packed in specialized containers, it's transported under controlled conditions to ensure safety during transit.
    Free Quote

    Competitive 4-Bromo-1-Difluoromethyl-2-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: info@alchemist-chem.com

    4-Bromo-1-Difluoromethyl-2-Fluorobenzene 4-Bromo-1-Difluoromethyl-2-Fluorobenzene
    General Information
    Historical Development
    4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene is also an organic compound. The beginning of its research was covered when many people studied the wonders of chemical synthesis. At first, it was only seen in the laboratory, but chemists worked hard to make this product with new techniques and new theories.
    At that time, the conditions were not as good as they are today, and all experiments needed to be cautious. However, the public's will was unremitting, and they explored the road of chemistry diligently. With the passage of time and the advancement of technology, the preparation of this compound has gradually matured.
    Since its inception, it has shown unique capabilities in various fields such as medicine and materials. Medicine, by virtue of its characteristics, helps the research of new drugs; materials, by virtue of its advantages, promote the formation of new quality. Looking at its historical evolution, from the discovery of micro to the wide use of the environment, it is one of the clear evidence of chemical development.
    Product Overview
    Today there is a substance called 4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene. This substance is the result of our painstaking research. Its color may be clear or slightly glossy, depending on the environment and the preparation method. Its properties are stable, and it is not easy to change violently with other substances under common temperature and pressure conditions.
    Looking at its structure, the position of the benzene ring, the bromine atom is located in the fourth, the difluoromethyl is in the first, and the fluorine atom is in the second. This unique structure gives it a different nature. In the field of organic synthesis, it is often a key raw material, which can lead to various reactions and produce diverse products. Either participate in nucleophilic substitution, or participate in addition change, all depend on the reaction conditions and accompanying reagents.
    Our research hopes to be able to use it in various industries such as medicine and materials, and contribute to the progress of the world.
    Physical & Chemical Properties
    4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene is an organic compound, and its physicochemical properties are particularly important. Looking at its physical properties, it is in a liquid state at room temperature and has a specific boiling point and melting point, which is related to its phase change at different temperatures. The value of its boiling point can help the planning of separation operations such as distillation. The melting point is also one of the key indicators to distinguish its purity.
    When it comes to chemical properties, the presence of bromine, fluorine and other atoms in this compound makes it have unique reactivity. Bromine atoms can participate in nucleophilic substitution reactions and can be replaced by other nucleophilic reagents, thereby deriving a variety of organic products. Fluorine-containing groups give them special electronic and spatial effects, which affect the polarity and chemical reaction selectivity of molecules. This compound can be used as a key intermediate in the field of organic synthesis to construct more complex organic molecular structures to meet the needs of pharmaceutical chemistry, materials science and other fields.
    Technical Specifications & Labeling
    4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene is an important organic compound. Its process specifications are related to the fineness of preparation, the purity of raw materials, reaction conditions such as temperature, pressure, catalyst, etc. If the reaction temperature is not appropriate, it may cause side reactions to breed and affect the purity of the product. The regulation of pressure should not be underestimated, but it is related to the reaction rate and balance.
    The identification of the product (commodity parameters) must accurately indicate its composition, purity and characteristics. The identification of purity must be accurate, which is the core indicator for measuring the quality of the product. The description of the trait should include appearance, smell, etc., so that the user can clearly understand its characteristics. Only in this way can we ensure that the product can be accurately applied in scientific research, production and other fields, and give full play to its due value.
    Preparation Method
    To prepare 4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene, its raw materials and production process, reaction steps and catalytic mechanism are the key. First take an appropriate amount of fluorobenzene as the initial raw material, add a brominating reagent in a specific reaction kettle, and control the temperature in a moderate range according to the precise ratio to make it fully react. This is the bromination step.
    After the bromination reaction is completed, add a reagent containing difluoromethyl, and with the help of a high-efficiency catalyst, adjust the pH and pressure of the reaction environment to promote its substitution reaction. This is the important step in introducing difluoromethyl.
    During the reaction process, it is necessary to strictly measure the composition and purity of the product at each stage, and use precision analytical instruments, such as chromatography analyzers, to control the reaction direction. After the reaction is completely completed, through distillation, extraction, recrystallization and other refining processes, pure 4-Bromo-1-Difluoromethyl-2-Fluorobenzene is obtained. In this way, attention is paid to the characteristics of raw materials, precise regulation of reaction conditions and rational use of catalytic mechanisms to achieve the purpose of efficient preparation.
    Chemical Reactions & Modifications
    Today there is a substance called 4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene. In the field of chemistry, it is crucial to explore its reaction and modification.
    Looking at the reaction, this compound meets with other substances, or undergoes a substitution change, or generates an addition response. At the time of substitution, the bromo group and the fluoro group can be used as a reaction site, and foreign objects or substitutes can be used to form a new structure. At the moment of addition, the unsaturated part of the molecule binds to other substances to expand its structure.
    As for modification, its properties can be adjusted by chemical methods. To increase its stability, or change its active site, so that the structure of the molecule is more stable. If you want to change the solubility, you can add suitable groups to make it easier to disperse in specific solvents. This is what chemists often think when exploring this compound, in order to clarify its properties, make good use of it, and add bricks to the progress of chemistry.
    Synonyms & Product Names
    Today there is a thing called 4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene. This thing is unique in the field of chemistry. Its synonymous names may vary due to research perspectives and regional differences.
    The sages of chemistry, exploring its nature, in order to seek accuracy, have different names. Although the names are different, they all refer to this thing. The name of the product also changes with the merchant and the use. Either to facilitate its promotion, or to meet specific needs, it is called another name.
    All synonymous names and product names are to clarify the quality and use of this thing. Those of us who study it should distinguish it carefully, understand its essence, and not be confused by the complexity of the name. In this way, we can get a glimpse of the mystery of chemistry, and make accurate use of the power of this thing when researching and applying it.
    Safety & Operational Standards
    4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene Safety Production and Operation Specifications
    For 4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene, chemicals are also very important in the chemical industry. To ensure its safe production and compliance with the operation, many specifications must be specified.
    First words Storage rules. This product should be placed in a cool, dry and well-ventilated place, away from direct sunlight. Exposure to sunlight, or cause the temperature to rise, causing all kinds of accidents. And it should be placed separately from oxidizing agents, reducing agents, alkalis, etc., because of their active chemical properties, they may react violently in case of them. In the storage place, prepare leakage emergency treatment equipment and suitable containment materials, just in case.
    Times and accurate operation. Operators must be specially trained, familiar with the operating procedures, and uphold a rigorous and serious attitude. When operating, appropriate protective equipment must be worn, such as gas masks, to prevent inhalation of harmful gases; wear chemical safety glasses to protect your eyes from damage; wear anti-toxic substances to penetrate the work clothes to avoid skin contact. The operation site should be well ventilated to reduce the concentration of harmful substances in the air.
    Furthermore, it is related to leakage treatment. If there is a leak, immediately evacuate unrelated personnel and isolate the leakage area. Emergency responders must wear protective gear and do not let leaks come into contact with skin and eyes. In the event of a small leak, it can be absorbed by inert materials such as sand and vermiculite and placed in a suitable container for disposal. If there is a large leak, it is necessary to build a dike or dig a pit to contain it, cover it with foam to reduce volatilization, and then transfer it to a tanker or a special collector with a pump for recycling or transportation to a waste treatment site for disposal.
    It is also necessary to transport. During transportation, ensure that the container does not leak, collapse, fall, or damage. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. It is strictly forbidden to mix with acids, flammable substances, organic substances, reducing agents, self-igniting items, and flammable items in case of moisture. During transportation, protect against sun exposure, rain, and high temperature.
    In short, the safe production and operation of 4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene must comply with the above specifications, and must not be slack at all, in order to ensure the safety of personnel, the environment is not damaged, and the production is orderly.
    Application Area
    4-Bromo-1-difluoromethyl-2-fluorobenzene is also a new product of chemistry. Its use is wide. In the field of medical medicine, it can be a raw material for making good medicines. Those who cover their special structure and can react with other things to produce healing properties. In the field of agriculture, it can become an agent for protecting seedlings, preventing diseases and insect pests, and ensuring the abundance of crops. In the study of materials, it can assist in the research of new materials, making them special, such as good weather resistance and electricity resistance. The emergence of this product has opened up a new path for various industries. Those who are waiting for research will explore its secrets in depth, expand a wider range of uses, so as to benefit people's livelihood and promote the progress of the world.
    Research & Development
    In recent years, Yu has dedicated himself to the research of organic compounds, focusing on the substance 4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene. This compound has a unique structure and has potential applications in many fields.
    At the beginning of the research, I was trapped in the synthesis method. The traditional path, the yield is quite low, and there are many impurities. Yu then read the classics, referred to the methods of various families, tried repeatedly, and finally obtained the improved technique. The new way uses a specific reagent, and after several steps of reaction, the yield is greatly improved, and the purity is also high.
    As for the application exploration, this compound is expected to become a key intermediate in the creation of medicine. After derivatization reaction, new drugs can be prepared to fight specific diseases. In materials science, it may improve material properties, such as enhancing stability and optimizing optical properties.
    There are still challenges ahead. Cost control and Environmental Impact Assessment for large-scale preparation need to be done with caution. Yu should continue to study, and hope that this compound will achieve great success in research and development and application, adding to the academic and industrial circles.
    Toxicity Research
    Today, there is a substance named 4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene. I work on toxicological research, so I pay attention to its toxicity. The toxicity of this substance is related to everyone's health and cannot be ignored.
    After various experiments, observe its phase transformation with other substances, and observe the signs of its entry into the body. See that under specific conditions, it can disrupt the normal order of cells and disturb the balance of physiology. Or damage the ability of organs, or hinder the transmission of nerves. Although its toxicity occurs, it cannot be observed for a while, but when it accumulates, it will be exposed over time.
    For everyone's sake, when it is produced and used, strict precautions should be taken, and the person who handles it must wear protective gear to avoid it. And where the object is placed, it should be clearly marked so that everyone is aware of its risks. In this way, everyone can be safe and protected from its poison.
    Future Prospects
    I try to study this product of 4 - Bromo - 1 - Difluoromethyl - 2 - Fluorobenzene. Looking at its properties, it has specific properties and has extraordinary performance in various reactions.
    Looking to the future, this product is expected to emerge in the field of medicine. Its unique structure may be used as a key component of targeted drugs to precisely attack lesions and treat diseases and diseases for patients. In material science, it may also be able to give birth to new functional materials. With its characteristics, the material has excellent properties, such as better stability and conductivity, which will contribute to material innovation.
    Although the road ahead may be difficult, the road to scientific research requires unremitting exploration. I firmly believe that with time, this product will be able to shine, open up new horizons for the well-being of mankind, and create brilliance for future development.
    Where to Buy 4-Bromo-1-Difluoromethyl-2-Fluorobenzene in China?
    As a trusted 4-Bromo-1-Difluoromethyl-2-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-1-Difluoromethyl-2-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-bromo-1-difluoromethyl-2-fluorobenzene?
    The main use of 4-Shen-1-divinyl-2-naphthalene is in the production of dyes, dyes and plastics.
    Rubber divinyl naphthalene, its performance is very good, and it can be used for the manufacture of dyes. It can be used as an important raw material for the manufacture of dyes. With this base, dyes with good color and fastness can be obtained, which can be used for printing and dyeing, so that the dyes have a colorful appearance.
    As for the field of dyes, divinyl naphthalene can be modified and transformed into compounds with specific chemical activities due to its special chemical production. It may be able to synthesize antibacterial, anti-cancer, etc., which is very difficult to solve and save many patients.
    For plastic engineering, divinylnaphthalene can be used as a polymer material with high performance. This plastic material may be characterized by high mechanical properties and resistance, and can be used in high-precision fields such as aviation and electronics, promoting the progress of science and technology.
    In addition, naphthalene derivatives are also involved in fragrances, light materials, etc. In fragrances, they can be used for special fragrance of products; in light materials, or in light materials that can affect the light properties of materials, such as refractive index, light, etc.
    Therefore, 4-Shen-1-divinyl-2-naphthalene plays an important role in the chemical industry. The depth of its use and influence cannot be ignored. It is an important angle for the development and improvement of people's livelihood.
    What are the physical properties of 4-bromo-1-difluoromethyl-2-fluorobenzene?
    4-Bromo-1-diethylamino-2-bromobenzene organic compound, its physical properties are as follows:
    In appearance, it is mostly colorless to light yellow liquid at room temperature and pressure, and its quality is uniform. This color property is helpful for preliminary identification and observation of it in experiments or industrial production, and it is easy to judge its purity and state changes.
    In terms of olfactory sense, it has a special smell. The smell is unique. When operating and using, the operator can initially judge whether there is an abnormal situation such as leakage by virtue of the smell, but because the substance may be toxic and harmful, it cannot be deliberately sniffed close to it.
    In terms of solubility, it can be soluble in common organic solvents, such as ethanol, ether, dichloromethane, etc. This solubility allows it to use these organic solvents as the reaction medium in the organic synthesis reaction to promote the smooth progress of the reaction. At the same time, during the separation and purification process, the appropriate solvent can be selected for extraction, recrystallization and other operations according to its solubility characteristics.
    Boiling point and melting point are also important physical properties. Its boiling point and melting point are affected by factors such as intermolecular forces and structures, and the specific values are boiling point [X] ° C, melting point [Y] ° C. The boiling point determines the temperature conditions to be controlled in separation operations such as distillation to ensure that the substance can be effectively separated from the mixture; the melting point helps to judge the purity of the substance. The melting point of pure substances is fixed. If impurities are contained, the melting point is usually reduced and the melting range is widened.
    In terms of density, the density is [Z] g/cm ³. This property is very critical in experimental operations or industrial production processes involving liquid-liquid mixing, stratification, etc., and can be separated from other liquids through density differences.
    In addition, the substance has a certain volatility. This means that during storage and use, it is necessary to pay attention to sealed storage to avoid its volatilization leading to concentration changes, losses, and harm to the environment and human body.
    Is 4-Bromo-1-difluoromethyl-2-fluorobenzene chemically stable?
    The chemical stability of 4-hydroxy-1,2-diethylamino-2-hydroxy-propyl depends on many factors.
    Looking at the structure of this compound, it contains functional groups such as hydroxyl groups and amine groups. Hydroxyl groups have certain activity and can participate in many reactions, such as esterification, which can form esters with acids under suitable conditions. This process is like craftsmen splicing different components with clever techniques. However, if there is no acid in the environment to echo it, esterification will be difficult to occur, and its chemical properties can be said to be relatively stable in this regard.
    Amine groups also have their own characteristics, are basic, and can neutralize with acids, just like yin and yang. If the environment is acidic, the amino group is easy to interact with the acid, and the chemical properties will be active; if it is in a neutral or alkaline environment, the reactivity of the amine group will be reduced, and the stability will be enhanced accordingly.
    Furthermore, the structure of the carbon chain in this compound is also affected. The carbon chain is relatively long and contains substituents, and the spatial structure also plays a role in the stability of its chemical properties. Under generally mild conditions, if there is no specific reagent or strong external factors, such as high temperature, strong oxidizing agent, strong reducing agent, etc., this compound can maintain a relatively stable state.
    However, once it encounters severe conditions, such as high temperature, the vibration of the chemical bond intensifies, which may cause it to break and cause reactions such as decomposition; in case of strong oxidants, both hydroxyl and amine groups may be oxidized, changing their chemical structure and properties.
    Therefore, the chemical stability of 4-hydroxyl-1,2-diethylamino-2-hydroxypropyl cannot be generalized, but depends on the specific environmental conditions and the substances in contact. In common mild environments, if there are no special reactants, it can remain relatively stable, but under extreme or specific reaction conditions, the chemical activity will be revealed, and various chemical reactions will occur.
    What are the synthesis methods of 4-bromo-1-difluoromethyl-2-fluorobenzene?
    The synthesis of 4-bromo-1-diethylamino-2-bromobenzene covers many ways.
    First, it can be started from a suitable benzene derivative. First, take the benzene containing the appropriate substituent. Under specific conditions, a brominating agent such as liquid bromine is used in the presence of a catalyst such as iron powder or iron tribromide. At this time, the bromine atom will be selectively introduced into a specific position in the benzene ring. Due to the positioning effect of the existing substituent on the benzene ring, the bromine atom can be guided to the target position to obtain a bromine-containing intermediate. Next, the intermediate is reacted with diethylamine. During the reaction, attention should be paid to the choice of reaction temperature and solvent. Polar aprotic solvents such as N, N-dimethylformamide are often used. At appropriate temperatures, the amino group of diethylamine can replace a certain halogen atom on the benzene ring. After careful post-treatment, such as extraction, distillation, recrystallization, etc., pure 4-bromo-1-diethylamino-2-bromobenzene can be obtained.
    Second, the method of gradually constructing the benzene ring can also be used. First, simple organic compounds containing bromine and amino groups are used as raw materials to construct the benzene ring through a series of reactions such as condensation and cyclization. For example, with appropriate brominated enamines, under specific catalysts and reaction conditions, the intramolecular cyclization reaction is carried out to form a phenyl ring structure, and bromine and amino-related substituents are introduced at the same time. Then, depending on the specific situation, the amino group is modified by ethylation to obtain the required diethylamino group, and the bromine atom may need to be protected and deprotected during the process, and each step of the reaction may be carefully regulated to finally complete the synthesis of 4-bromo-1-diethylamino-2-bromobenzene.
    Synthesis requires precise control of the reaction conditions at each step, proper selection of solvent, temperature, catalyst, and effective separation and purification of intermediates, so that the target compound can be efficiently obtained.
    What is the price range of 4-bromo-1-difluoromethyl-2-fluorobenzene in the market?
    In the business of the world, changes in prices often vary with time, place, and supply and demand. As for the market price of 4-hydroxyl-1,2-diethylamino-2-hydroxypropyl, this rule is also followed.
    This product is in the market, and its price is not constant, due to many reasons. First, the price of raw materials, if the raw material is rare, the cost of its production will increase, and the price will also rise; on the contrary, the raw material is abundant, and the price may drop. The two are the fineness of the craftsmanship. If the craftsmanship is excellent, the production efficiency is high and the quality is high, and the price may be appropriate; if the craftsmanship is poor, the production is low and the quality is inferior, and the price is difficult to be low. The three are the supply and demand of the market. If there is a need for prosperity and a lack of supply, the price will be high; if there is an oversupply, the price will fall.
    However, it is not easy to determine the range of the price. The market conditions are ever-changing, and there are differences in different places. Or in prosperous commercial ports, where transactions are frequent, the price may be leveled due to competition; in remote places, where supply and transportation are inconvenient, the price may be slightly higher.
    I have heard that such goods, at the market price, may be low or tens of dollars a catty, and high or hundreds of dollars a catty. However, this is only an approximate number, and the actual price shall be subject to the real-time market conditions and the difference in quality. To obtain a definite price, you need to widely observe the market conditions and consult merchants before you can obtain it. In short, the city is impermanent, and the price is indeterminate. It is necessary to adapt to local conditions according to time and conditions, and study the school in detail to know the approximate price.