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4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene

4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene

Hongda Chemical

    Specifications

    HS Code

    613956

    Chemical Formula C8H4BrF5O
    Molecular Weight 291.01
    Appearance Colorless to light yellow liquid
    Boiling Point 170 - 172°C
    Melting Point N/A
    Density 1.73 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents
    Flash Point 67°C
    Vapor Pressure N/A
    Stability Stable under normal conditions
    Hazard Class Irritant

    As an accredited 4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4 - bromo - 1 - difluoromethoxy - 2 - trifluoromethyl - benzene in sealed chemical - grade bottle.
    Storage Store 4 - bromo - 1 - difluoromethoxy - 2 - trifluoromethyl - benzene in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly closed container to prevent evaporation and contamination. Avoid storage near incompatible substances to prevent chemical reactions. Use proper labeling for easy identification.
    Shipping 4 - bromo - 1 - difluoromethoxy - 2 - trifluoromethyl - benzene is shipped in specialized, tightly - sealed containers. They're carefully packed to prevent leakage, following strict chemical transportation regulations for safe and compliant delivery.
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    4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene 4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene
    General Information
    Historical Development
    4-Bromo-1-difluoromethoxy-2-trifluoromethylbenzene has a long history of development. In the past, chemical researchers moved forward step by step on the road of material exploration. At the beginning, the understanding of this thing was still shallow, and only a little bit of its characteristics were known. However, with unremitting research, the mystery of its structure gradually became clear. After years of experiments, the synthesis method was improved. At the beginning, the synthesis was difficult, and the yield was quite low, but everyone was determined. With the advance of science and technology, new technologies and new machines have entered the research, and the road of synthesis has gradually widened, and the yield has also been rising. Today's 4-bromo-1-difluoromethoxy-2-trifluoromethylbenzene is no longer comparable to the past, emerging in many fields. Its historical development is the crystallization of the efforts and wisdom of chemical researchers.
    Product Overview
    Today there is a substance called 4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene. The shape of this substance may be a crystal of pure color and uniform quality, or a clear and transparent liquid, which varies depending on the environment.
    Looking at its structure, the bromine atom is stable in one place, and the ortho position is a group containing trifluoromethyl, which contrasts with each other, giving this substance a unique property. There is also a difluoromethoxy group, which is tied to the benzene ring, just like a pearl embellishment, which enhances its brilliance a lot.
    This substance is widely used in the field of chemical industry. It can be used as a key raw material for the synthesis of exquisite drugs to help doctors heal diseases; or as a cornerstone for the creation of special materials, used in aerospace and other high-tech industries, to help equipment be sturdy and durable. It is also an indispensable item in the process of scientific research, and many talents use it to explore the unknown to start a new chapter in chemistry.
    Physical & Chemical Properties
    4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene is a unique compound. Its physical and chemical properties are very interesting. Looking at its morphology, it is a colorless liquid at room temperature and has a special odor. Regarding its boiling point, it is about a certain temperature range, due to the force between molecules. The melting point also has its specific value, which is limited by the molecular structure. In terms of chemical properties, the substituents on its benzene ring give it unique reactivity. Bromine atoms are active and can participate in reactions such as nucleophilic substitution. Fluorine-containing groups give compounds high stability and unique electrical properties. Due to its special physical and chemical properties, it may have potential applications in the fields of materials science, medicinal chemistry, etc. It can be used as a building block for new materials or as a key intermediate for drug development.
    Technical Specifications & Labeling
    4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene is an important chemical product. Its technical specifications and identification (product parameters) are extremely critical.
    The technical specifications of this product are related to its physical and chemical properties. Such as appearance, or a colorless and transparent liquid, with a specific boiling point and melting point, it is related to its state under different conditions. Its purity must reach a high standard, and the impurity content should be minimal to ensure its stable performance in various reactions or applications.
    In terms of labeling, product parameters should be clear. On the packaging, the chemical name and molecular formula should be clearly marked so that the user can see it at a glance. And should be attached to the hazard label, because it may have certain toxicity, corrosive and other hazards, warning users to take precautions when operating. In this way, the product can be safely and efficiently circulated in production, transportation, use and other links.
    Preparation Method
    The raw materials of 4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene are the key to the production process, reaction steps and catalytic mechanism.
    First take an appropriate amount of bromine-containing benzene derivatives as the base material, add a specific proportion of fluorine-containing reagents, put them in a well-prepared reactor, and control the temperature in a suitable range. This is the initial step. The addition of fluorine reagents requires a precise process to ensure the steady progress of the reaction.
    In the reaction process, the catalytic mechanism is the core. Choose the appropriate catalyst to promote the efficient occurrence of the reaction. This catalyst can cleverly reduce the activation energy of the reaction, make the intermolecular collision more effective, and accelerate the formation of the target product.
    As for the production process, the materials need to be mixed evenly, and the reaction time needs to be precisely controlled. After the reaction is completed, the impurities are removed through fine separation and purification to obtain pure 4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene. Each step is related to the purity and quality of the product, and cannot be slack.
    Chemical Reactions & Modifications
    The chemical reaction and modification of 4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene are studied. Chemical changes are related to the change of substances, and the reaction path of this compound is the key to research.
    Looking at its structure, the coexistence of halogen atoms and special groups must make it uniquely reactive. Bromine atoms are active and can initiate nucleophilic substitution, interact with many nucleophilic reagents, or form new bonds to change their structures. The existence of fluoromethoxy groups and trifluoromethyl groups affects the distribution of electron clouds in molecules, and the reactivity and selectivity are different from those of normal substances.
    As for modification, it can be controlled by reaction conditions, such as changes in temperature, solvent, and catalyst, to lead it to form the desired product. Or introduce other groups to obtain new properties and be more widely used in materials, medicine, etc. Therefore, exploring its chemical reaction and modification is of great benefit to the advancement of chemistry and the expansion of applications.
    Synonyms & Product Names
    4-Bromo-1-difluoromethoxy-2-trifluoromethylbenzene, this substance is widely used in today's chemical industry. Its synonymous names are also many. In the industry, it may be called a special bromofluorobenzene, due to the unique arrangement of bromine and fluorine atoms in the structure. Its trade name may vary according to different manufacturers and uses. There are those named to highlight its fluorine characteristics, in order to highlight its special properties in specific reactions and product applications due to the introduction of fluorine atoms.
    Ancient theory, although there is no such precise chemical name, it can also be expressed as one or two of its characteristics in ancient Chinese. Its structure is unique, like an ancient treasure, containing the stability of bromine and the vitality of fluorine. The two are blended on the benzene ring, just like a strange thing embedded in a stable cornerstone. The variety of its synonymous names and commodity names is also like an ancient treasure. The names of different places vary depending on where they are used and who they meet.
    Safety & Operational Standards
    4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene Safety and Operation Specifications
    Fu 4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene is an important substance in chemical research. During its experimental operation and use, safety is the key, and specific operating specifications must be followed.
    First of all, handle this substance when it is in a well-ventilated experimental site. Because it may be volatile, if the ventilation is not smooth, harmful gases will accumulate, endangering the health of the operator. And must avoid direct contact with the skin and eyes. If you accidentally touch it, you should immediately rinse it with a large amount of water. If the situation is serious, seek medical treatment urgently.
    Furthermore, when storing, it must be placed in a cool, dry place away from fire and heat sources. Due to its chemical properties, it may cause dangerous reactions in case of heat or fire. Packaging should also be tight to prevent leakage.
    As for the operating specifications, when taking it, use a precise measuring tool and measure it accurately according to the experimental requirements, and do not increase or decrease it at will. When stirring and other operations, the speed is moderate to prevent overreaction. After the experiment is completed, the remaining materials cannot be discarded at will, and they should be properly disposed of in accordance with relevant regulations to avoid polluting the environment.
    All of these are the essentials of the safety and operation of 4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene. The operator must always keep in mind that strict regulations are followed to ensure the smooth operation of the experiment, and the safety of themselves and the environment.
    Application Area
    4-Bromo-1-difluoromethoxy-2-trifluoromethylbenzene, this compound has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help develop new specific drugs, or to optimize the structure of existing drugs to improve efficacy and safety. In the field of pesticides, it can lay the foundation for the creation of high-efficiency, low-toxicity and environmentally friendly pesticides to enhance the control effect of crop diseases and pests. In the field of materials science, it can participate in the synthesis of functional materials, giving materials unique electrical, optical or thermal properties, such as application in new display materials, semiconductor materials, etc., so as to meet the needs of different fields for special materials, showing great potential and value in many application fields.
    Research & Development
    In recent years, I have focused on the research of 4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene. This compound has unique properties and has potential applications in many fields.
    At the beginning, the road to synthesis was full of thorns. The ratio of raw materials, reaction temperature and time all need to be carefully controlled. If there is a slight difference, the yield will be greatly reduced. However, after unremitting exploration, after repeated experiments, the final optimization method was obtained, and the yield was steadily improved.
    At the same time, in-depth exploration of its reaction mechanism was carried out. With modern analytical methods, the mystery of intermolecular interaction was gained, which laid the foundation for further improvement of the synthesis process.
    Looking forward to the future, we hope to expand the application of this research result. I will do my best to promote the development of 4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene and make a modest contribution to the academic community and industry.
    Toxicity Research
    Today there is a substance called 4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene. As a chemical researcher, I investigate its toxicity.
    The toxicity study of this substance is related to everyone's life and death and well-being, which cannot be ignored. After repeated tests, we have carefully observed its reaction with various substances and its effect on living beings. Observing the path of its transportation and transformation in the body, we can know that it may disturb the order of biochemistry and damage the ability of the viscera.
    Although the toxicity is clear, it cannot be achieved overnight, but every proof obtained is the key. We must be careful to understand the depth of toxicity of this chemical and the mechanism of action, so as to avoid disasters and make it a blessing for the world, so that this substance can be used in a way that will not harm the world. In this way, it is not the responsibility of the researcher.
    Future Prospects
    Wuguanfu 4 - Bromo - 1 - Difluoromethoxy - 2 - Trifluoromethyl - Benzene This product has unique properties and a wide range of uses. Looking forward to the future, there is much to be done.
    In today's world, science and technology are changing, and this compound is expected to shine in various fields. In the field of medicine, it may be possible to use its characteristics to develop new agents to treat various diseases and save patients from hardship. In the field of materials, it may be able to help make specific materials, increase their performance, and make utensils more durable and durable.
    Although the road of my research is difficult, we scientific researchers should have perseverance and unremitting exploration. With time, we will be able to understand more of its mysteries and make it better for the world, which is also a great hope for the future. We should work tirelessly and look forward to seeing this compound bloom in a brilliant light in the future, adding luster to the well-being of mankind.
    Where to Buy 4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene in China?
    As a trusted 4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene?
    4-Bromo-1-difluoromethoxy-2-trifluoromethylbenzene is one of the organic compounds. It has a wide range of uses and plays an important role in many fields.
    In the field of medicinal chemistry, this compound can be used as a key intermediate to help synthesize a variety of specific drugs. The bromine atom, difluoromethoxy group and trifluoromethyl group contained in the genome molecule give it unique chemical properties and biological activities. Through organic synthesis, chemists can skillfully transform it into compounds with specific pharmacological activities, such as for the development of new drugs such as antiviral and anti-tumor drugs.
    In the field of materials science, 4-bromo-1-difluoromethoxy-2-trifluoromethylbenzene also has potential uses. Due to the presence of fluorine atoms, it can improve the physical properties of materials, such as enhancing the chemical resistance, thermal stability and surface properties of materials. Therefore, it may be used to prepare high-performance polymer materials, coating materials, etc., and be used in high-end fields such as aerospace and electronics.
    In the field of agricultural chemistry, this compound may also play a role. With its special chemical structure, it may be used to synthesize pesticides with high insecticidal and bactericidal activities. It can precisely act on specific pest targets and contribute to ensuring crop yield and quality.
    In summary, although 4-bromo-1-difluoromethoxy-2-trifluoromethylbenzene is an organic compound, it has important uses in many fields such as medicine, materials, and agriculture, and is of great significance to promoting scientific and technological progress and industrial development in various fields.
    What are the physical properties of 4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene?
    4-Bromo-1-difluoromethoxy-2-trifluoromethylbenzene is a member of the family of organic compounds. Its physical properties are unique and worthy of careful investigation.
    Looking at its appearance, under normal circumstances, this substance is mostly a colorless to light yellow transparent liquid, which is clear and has a specific visual appearance. This morphology is conducive to observation and processing in many chemical operations and applications.
    Smell, the compound emits a unique odor, but this odor is quite special and needs to be carefully identified in a professional environment. Its odor characteristics may be used as a basis for preliminary identification in some application scenarios, or have a certain impact on the surrounding environment and user senses.
    Talking about the melting point, due to the specific arrangement and interaction of molecular structure, the melting point of 4-bromo-1-difluoromethoxy-2-trifluoromethylbenzene is in a relatively specific range. This melting point value plays a key role in defining the physical state transition of the substance under different temperature conditions. When the external temperature approaches or reaches the melting point, the substance will gradually change from solid state to liquid state, which is of great significance in the fields of material processing, separation and purification.
    The boiling point of this compound also has its own inherent value. The boiling point reflects the temperature conditions required for the substance to transform from liquid state to gas state under a specific pressure environment. Its boiling point characteristics provide an important parameter reference for the separation and purification of this substance in chemical operations such as distillation and rectification. Appropriate temperature control can ensure that the substance can be effectively separated or interacted with other substances in a specific process.
    In terms of solubility, 4-bromo-1-difluoromethoxy-2-trifluoromethylbenzene exhibits a certain tendency to dissolve in common organic solvents. For example, in some non-polar organic solvents, it can exhibit good solubility, which makes it possible to select a suitable solvent system in the organic synthesis reaction to promote the smooth progress of the reaction. In polar solvents, its solubility may be greatly limited, which is crucial for designing chemical reaction paths and selecting suitable reaction media.
    density is also one of the important physical properties of the substance. The specific density value indicates the quality of the substance per unit volume, which provides indispensable data support for ensuring product quality and reaction effect in chemical processes such as precise measurement and mixing ratio control.
    In summary, the physical properties of 4-bromo-1-difluoromethoxy-2-trifluoromethylbenzene are interrelated and play an important role in chemical research, chemical production and related application fields, laying a solid foundation for the effective utilization and in-depth exploration of this substance.
    What are 4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene synthesis methods?
    The synthesis of 4-bromo-1-difluoromethoxy-2-trifluoromethylbenzene is an important topic in organic synthetic chemistry. The synthesis methods vary widely, depending on the raw materials and reaction conditions.
    One method can be initiated by a benzene derivative containing the corresponding substituent. If benzene with a suitable substituent is used as the raw material, bromine atoms are introduced through halogenation reaction. For this halogenation reaction, a suitable brominating reagent can be selected, such as bromine (Br ²), which reacts with benzene derivatives under the action of a catalyst to introduce bromine atoms at specific positions.
    Then, to introduce a difluoromethoxy group, a nucleophilic substitution reaction can be used. Select appropriate bis fluoromethoxylation reagents, such as active compounds containing difluoromethoxy, to react with brominated benzene derivatives. During the reaction, attention should be paid to the control of reaction conditions, such as temperature and solvent selection. Suitable solvents may promote the reaction and improve the yield of the product.
    As for the introduction of trifluoromethyl, there are also various strategies. You can choose a reagent containing trifluoromethyl to react with benzene derivatives containing bromine and difluoromethoxy through specific reaction conditions. Or use a transition metal-catalyzed reaction to achieve the precise introduction of trifluoromethyl. In this process, the choice and dosage of transition metal catalysts have a great impact on the selectivity and efficiency of the reaction.
    There is another method, or the reaction sequence can be changed. Trifluoromethyl is introduced first, and then bromination and difluoromethoxylation are carried out. The change of this sequence, or due to the different effects of different substituents on subsequent reactions, requires detailed optimization of the reaction conditions in each step to achieve the best synthesis effect.
    In addition, during the reaction process, the separation and purification of intermediates is also key. After each step of the reaction, appropriate separation and purification operations, such as column chromatography and recrystallization, can improve the purity of the final product and ensure the feasibility and reliability of the synthesis route. There are many ways to synthesize 4-bromo-1-difluoromethoxy-2-trifluoromethylbenzene, and the synthesis method should be carefully selected and optimized according to the actual situation, considering the availability of raw materials, the difficulty of reaction conditions, the yield and purity and other factors.
    What are the precautions in storage and transportation of 4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene?
    4-Bromo-1-difluoromethoxy-2-trifluoromethylbenzene is an organic compound. During storage and transportation, many matters must be paid attention to.
    This compound is chemically active and may be sensitive to heat. When storing, choose the first environment, and it should be placed in a cool, dry and well-ventilated place. Be sure to keep away from fire and heat sources, because heat can easily cause it to decompose or cause dangerous reactions. Excessive temperature may cause changes in the structure of the compound, resulting in changes in its properties, and even may cause serious consequences such as explosion.
    Furthermore, the storage place should be separated from oxidants, reducing agents, acids, bases, etc., and must not be stored in mixed storage. Because of its active chemical properties, contact with the above substances, or trigger violent chemical reactions, causing the risk of fire and explosion. For example, if it coexists with strong oxidizing agents, or an oxidation reaction occurs, a large amount of energy is released, which can lead to accidents.
    The transportation process should also not be taken lightly. It is necessary to ensure that the packaging is complete and sealed. If the packaging is damaged, compounds or leaks, it will not only pollute the environment, but also pose a threat to the safety of transporters. The means of transportation should also be clean and dry, free of other impurities that may react with it. When transporting, it should also follow the specified route to avoid densely populated areas and important facilities to prevent accidents during transportation and cause serious damage to people's lives and facilities.
    In addition, whether it is storage or transportation, relevant personnel should be familiar with the characteristics of the compound and emergency treatment methods. In the event of a leak or fire, it can respond quickly and correctly. In the event of a leak, immediate evacuation of surrounding personnel is required to isolate the leak area. Emergency responders should wear appropriate protective equipment to prevent exposure to poisoning, and then take corresponding collection and cleaning measures.
    In short, the storage and transportation of 4-bromo-1-difluoromethoxy-2-trifluoromethylbenzene must strictly follow relevant norms and requirements, and operate with caution to ensure personnel safety and environmental safety.
    What is the market price of 4-Bromo-1-Difluoromethoxy-2-Trifluoromethyl-Benzene?
    4-Bromo-1-difluoromethoxy-2-trifluoromethylbenzene, the market price of this product is difficult to determine. The chemical market is unpredictable, and the price varies with supply and demand, season, origin, and quality.
    In the past, if the demand for this product is strong and the supply is limited, the price will rise; if the supply exceeds the demand, the price may fall. In different places, due to transportation, taxes, etc., the price is also different.
    And its quality, the price of pure is high, and the price of miscellaneous is low. And the price of chemical raw materials often fluctuates due to international situations, policies and regulations. If environmental protection becomes stricter, production is limited, and prices may rise; if the international economic situation is poor, demand is sluggish, and prices are easy to fall.
    To know the exact market price, you can only get it by consulting chemical raw material manufacturers, trading platforms, or looking at recent market transaction data. However, at this moment I can't tell what the price is.