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4-Bromo-1-Chloro-3,5-Difluorobenzene

4-Bromo-1-Chloro-3,5-Difluorobenzene

Hongda Chemical

Specifications

HS Code

633826

Chemical Formula C6H2BrClF2
Molar Mass 229.43 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 174 - 176 °C
Melting Point N/A
Density 1.83 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 70 °C
Refractive Index 1.520 - 1.523
Purity Typically high - purity, e.g., 98%+

As an accredited 4-Bromo-1-Chloro-3,5-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - bromo - 1 - chloro - 3,5 - difluorobenzene in a sealed chemical - grade bottle.
Storage 4 - bromo - 1 - chloro - 3,5 - difluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant material. Label the storage container clearly with the chemical name and relevant safety information to prevent misuse.
Shipping 4 - bromo - 1 - chloro - 3,5 - difluorobenzene is shipped in well - sealed, corrosion - resistant containers. It's handled with care during transit, following strict regulations for chemical transport to ensure safety and integrity.
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4-Bromo-1-Chloro-3,5-Difluorobenzene 4-Bromo-1-Chloro-3,5-Difluorobenzene
General Information
Historical Development
4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene is also an organic compound. Its research and development process is really meaningful. In the past, the art of organic synthesis was not as sophisticated as it is today, and it was not easy to obtain this compound. The researchers worked hard and tried countless times. At first, the synthesis method was cumbersome and the yield was low. However, the researchers did not give up. After years of delay and unremitting exploration, new technologies gradually emerged. From the fine adjustment of reaction conditions to the new selection of raw materials, there have been changes. Eventually, the synthesis process became smoother and the yield also increased. This compound is increasingly used in the fields of medicine and materials. The process of its research and development has witnessed the evolution of synthetic chemistry, from simple to complex, from difficult to easy to achieve, which is a lesson for future researchers and promotes the continuous development of chemistry.
Product Overview
Today there is a substance called 4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene. It is an organic halogenated aromatic hydrocarbon with a unique molecular structure, containing bromine, chlorine, and fluorine atoms. Bromine atom occupies 4 positions, chlorine atom is 1 position, and difluorine atom occupies 3 and 5 positions.
This substance has special properties and has high reactivity due to the electronic effect of halogen atoms. It can be used as a key intermediate in organic synthesis and is widely used in pharmaceutical chemistry, materials science and other fields. In drug research and development, it can help create new drug molecules; in material synthesis, it can make functional materials with special properties. The method of
synthesis, or through halogenation reaction, select suitable aromatic hydrocarbon substrates, control the reaction conditions, and introduce various halogen atoms. However, when synthesizing, it is necessary to pay attention to the reaction selectivity and yield in order to achieve the desired effect. It is of great value in the stage of organic synthesis and has promising prospects.
Physical & Chemical Properties
4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene is an organic compound, and its physical and chemical properties are quite critical. Looking at its physical properties, it is mostly colorless to light yellow liquid under normal conditions, with specific volatility. Due to the molecular structure containing halogen atoms, its boiling point is relatively high, about 150 - 170 ° C, the density is greater than that of water, and it is difficult to dissolve in water, but it is easily soluble in common organic solvents, such as ethanol, ether, etc.
In terms of chemical properties, its halogen atoms are active and can participate in many chemical reactions. For example, nucleophilic substitution reactions, due to the electron-withdrawing action of halogen atoms, the electron cloud density of benzene rings decreases, making nucleophilic reagents easy to attack benzene rings and replace with halogen atoms. For example, under certain conditions, the elimination reaction can occur, and the halogen atom is separated from the hydrogen atom on the adjacent carbon atom to form an unsaturated bond. The study of the properties of this compound is of great significance to the development of organic synthesis and related fields.
Technical Specifications & Labeling
For 4-bromo-1-chloro-3,5-difluorobenzene, the quality of chemistry is also. Looking at its preparation, it must follow strict technical specifications. In the reaction chamber, all kinds of materials are gathered according to precise proportions. The purity of its raw materials is related to the quality of the product. The temperature of the reaction may need to be controlled by a temperature control device, and a certain degree should be kept, so that the millimeter should not be poor. The control of time is also the key. If it is too long or not enough, the product can be impure.
Test its quality, and there should be clear standards. Measure its purity with an instrument, and the amount of impurities must be subtle. The color and state of the appearance should conform to the established rules. Its melting point and boiling point also need to be accurate to be qualified. In this way, strictly abide by technical specifications and quality standards to obtain high-quality 4-bromo-1-chloro-3,5-difluorobenzene.
Preparation Method
The method of making 4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene involves raw materials and production processes, reaction steps and catalytic mechanisms. First, an appropriate amount of fluorine-containing raw materials is taken, and they are reacted in a specific container according to specific proportions and reaction conditions. This process requires precise temperature and pressure control to promote the positive progress of the reaction. At the beginning of the reaction, the raw materials interact, and through a series of complex chemical changes, intermediate products are gradually formed. Then, with suitable catalysis, the reaction process is accelerated, and the intermediate products are further converted. After multiple steps of reaction, the crude product is obtained. After purification processes, such as distillation, extraction, etc., impurities are removed to obtain pure 4-Bromo-1-Chloro-3,5-Difluorobenzene. The whole production process needs to be strictly controlled to ensure product quality and output.
Chemical Reactions & Modifications
The chemical industry is related to the change of all things, among which chemical reaction and modification are particularly critical. Today, 4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene is discussed.
In the process of synthesis, the reaction method is quite important. Or by halogenation, bromine, chlorine, and fluorine atoms are precisely introduced to form this specific structure. However, the reaction conditions, such as temperature, solvent, and catalyst, need to be studied in detail. High or low temperature can cause the reaction to be biased and the product is impure.
As for the modification method, the conversion of functional groups can be used to make it have different properties. Or increase its stability, or change its solubility to suit different purposes. If you want to use it for a specific organic synthesis, you can adjust its structure according to your needs to make the reaction smoother and the product better. All these are chemical researchers who should think deeply and study carefully. They can make good use of the method of reaction and modification to contribute to the progress of chemical industry.
Synonyms & Product Names
4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene is an important chemical substance. The discussion of its synonyms and trade names is very crucial in our chemical research.
This substance may have many names, which are derived from different research purposes and application scenarios. As far as synonyms are concerned, chemists may give it different expressions according to its chemical structure characteristics, synthesis paths, etc., but they all refer to this substance.
As for the trade name, due to market demand and commercial considerations, each merchant may take a different name to promote its products. However, no matter what the name is, its core is this 4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene.
A detailed study of its synonyms and trade names will help us accurately grasp the dynamics of this object in the academic world and the market, and is of great significance in chemical research and industrial applications.
Safety & Operational Standards
4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene is an important chemical substance. Many regulations need to be strictly adhered to in terms of experimental operation and safety assurance.
Anyone who participates in the experiment of this substance should be familiar with its physical and chemical properties in advance. This substance has specific reactivity, and understanding its characteristics is the basis for safe operation.
In the experimental operation room, it is necessary to ensure that the environment is well ventilated. Because it may be volatile, good ventilation can effectively reduce the concentration of this substance in the air and avoid danger caused by accumulation. When operating, the experimenter should wear appropriate protective equipment, such as laboratory clothes, gloves and goggles. Gloves need to be resistant to the erosion of this substance, and goggles can fully protect the eyes from possible splash damage.
When taking 4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene, use a precise measuring tool and strictly control the dosage. The weighing process needs to be carried out in a smooth and clean environment to prevent impurities from mixing in. And the operation should be steady and slow to avoid the spilling of the substance due to excessive movement range.
If the substance is accidentally spilled during the experiment, do not panic. Proper cleaning measures should be taken immediately. A small amount of spillage can be covered with a suitable adsorption material, and then carefully collected into a specific waste container. In the event of a large number of spills, in addition to evacuating people in time, the scene should be quickly sealed and professionals should be notified to deal with it.
Storage of 4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene also requires caution. It should be stored in a cool, dry and ventilated place, away from fire sources and oxidants. Storage containers must be well sealed to prevent leakage and volatilization. At the same time, key information such as the name of the substance and hazardous characteristics should be clearly marked on the outside of the container.
Only by strictly following the above safety and operating practices can we ensure that the experiments related to 4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene are carried out in a safe and orderly manner, effectively avoid various potential risks, and ensure the safety of the experimental personnel and the smooth progress of the experiment.
Application Area
4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene is a unique chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, this compound is often a key intermediate, helping medical researchers to create new specific drugs. With its unique chemical structure, it may be able to derive drugs with excellent efficacy for specific diseases.
In the field of materials science, due to its special halobenzene structure, it can participate in the preparation of high-performance materials. It can improve the stability and conductivity of materials, and then be used in electronic devices, optical materials and other fields to promote the innovation and development of related technologies.
In the field of organic synthetic chemistry, 4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene, with its unique combination of functional groups, provides an important starting material for the synthesis of complex organic molecules, enabling chemists to explore novel synthetic pathways and enrich the variety and properties of organic compounds.
Research & Development
In recent years, in the field of chemistry, I have focused on the research of 4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene. Its unique nature, in the process of organic synthesis, has great potential.
At the beginning, the study of its preparation method was repeatedly hindered. The choice of raw materials and the control of conditions are all difficult problems. However, I did not give up. After repeated experiments, the variables were carefully observed, and finally a feasible method was obtained. The yield gradually increased, and the quality was also excellent.
Having obtained a good recipe, I have re-explored its application. In the field of drug research and development, I tried to combine various compounds to obtain specific drugs. And in material science, observe its impact on material properties. After long-term research, I gradually understand its value in various fields.
In the future, I will continue to study this thing. Expand its application and explore its unknown nature. With unremitting efforts, I will make greater progress in the research and development of this thing and contribute to the development of chemistry.
Toxicity Research
Today there is a product called 4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene. As a chemical researcher, it is urgent to investigate its toxicity.
The toxicity study of this product is related to the health of everyone and the tranquility of the environment. After many investigations, we have observed its impact on various organisms through scientific methods. In the experiment, we took various organisms as samples to observe the changes after exposure to this product.
At first, it can be seen that some organisms have different behaviors, or slow movements, or no diet. Then, we deeply explore the mechanism in the body to observe the changes in cells and changes in biochemical indicators. It is found that this product disturbs the metabolism of some cells and affects the normal physiology of organisms.
Although the research is not complete, it is already clear that the toxicity of this product does exist. In the future, we should be more cautious, delve into it, and find ways to deal with it, so as to protect all living beings from its harm and the environment from its disturbance. I hope that with the efforts of my generation, the world will be aware of its toxicity and prevent problems before they occur.
Future Prospects
4 - Bromo - 1 - Chloro - 3,5 - Difluorobenzene is a key raw material for organic synthesis and has broad prospects in the fields of medicine and pesticides. Future development will focus on optimizing the synthesis process. We can develop more efficient and green synthesis paths to reduce energy consumption and pollution, which is in line with the needs of the times.
Furthermore, with the advancement of science and technology, the investigation of its derivatives will also be deepened. New compounds with unique properties may be obtained through structural modification and applied to emerging fields. And in the analysis and detection technology, it will become more accurate and sensitive, helping us to understand its properties and reaction mechanism in depth. In this way, 4 - Bromo - 1 - Chloro - 3, 5 - Difluorobenzene will surely shine in the future, contributing to the development of many industries.
Where to Buy 4-Bromo-1-Chloro-3,5-Difluorobenzene in China?
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Frequently Asked Questions

As a leading 4-Bromo-1-Chloro-3,5-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 4-Bromo-1-Chloro-3,5-Difluorobenzene?
4-Bromo-1-chloro-3,5-difluorobenzene is one of the organic compounds. Its chemical properties are unique and worth exploring.
In this compound, bromine, chlorine and fluorine atoms have their own characteristics, which have a profound impact on their overall properties. Bromine atoms have certain electronegativity and a large atomic radius, which makes them a good leaving group for nucleophilic substitution reactions in chemical reactions. When encountering nucleophilic reagents, bromine atoms are easily replaced, resulting in a variety of products.
Chlorine atoms also have considerable electronegativity. Although their radius is smaller than that of bromine atoms, they can also affect the distribution of electron clouds in molecules. In some reactions, chlorine atoms may participate in the reaction or affect the reactivity of neighboring atoms.
And two fluorine atoms, due to their extremely high electronegativity, cause the electron cloud of the molecule to be strongly biased towards the fluorine atom. This not only changes the polarity of the molecule, but also greatly enhances the stability of the molecule. The presence of fluorine atoms often makes compounds exhibit special selectivity in certain reactions.
In common organic reaction types, 4-bromo-1-chloro-3,5-difluorobenzene can undergo nucleophilic substitution reactions. If it interacts with nucleophiles containing nitrogen, oxygen, sulfur, etc., bromine or chlorine atoms can be replaced. Due to the presence of aromatic rings, electrophilic substitution reactions can also be carried out. However, due to the electron-withdrawing effect of fluorine atoms, the reaction check point may be slightly different from that of ordinary benzene derivatives, and most of them occur in relatively high electron cloud densities.
In terms of stability, due to the strong electron-withdrawing action of fluorine atoms, the electron cloud density of aromatic rings decreases, and the resistance to oxidation and reduction is enhanced. However, at the same time, this may also lead to more severe reaction conditions in some reactions that require activation of aromatic rings.
Its physical properties are also related to chemical properties. Due to the change of molecular polarity, the solubility in different solvents may vary. Overall, the chemical properties of 4-bromo-1-chloro-3,5-difluorobenzene are rich and colorful due to the synergistic effect of bromine, chlorine and fluorine atoms, and have potential application value in organic synthesis and other fields.
What are the common uses of 4-Bromo-1-Chloro-3,5-Difluorobenzene?
4-Bromo-1-chloro-3,5-difluorobenzene is also an organic compound. Its common uses involve a wide range of fields.
It is used in pharmaceutical chemistry and is a key intermediate. Through the wonderful method of organic synthesis, with suitable reaction reagents, it can be turned into bioactive pharmaceutical ingredients through delicate steps. Such as creating specific targeted drugs, targeting specific diseases, and assisting in the development of medicine.
It also has extraordinary functions in the field of materials science. It can be the cornerstone of the synthesis of special polymer materials. After polymerization, etc., the structure is integrated into the polymer chain, giving the material unique properties, such as improving the heat resistance and chemical corrosion resistance of the material, or changing its optical characteristics, for photoelectric materials.
In the pesticide chemical channel, it can be used as a raw material for the creation of high-efficiency pesticides. After rational molecular design and reaction construction, pesticides with insecticidal, bactericidal and other effects are produced, which contributes to agricultural plant protection.
Synthesis of this compound often follows the principle of organic halogenation reaction. Using benzene as the initial substrate, through halogenation reaction, bromine, chlorine and fluorine atoms are ingeniously introduced. Choose suitable halogenation reagents, such as brominating agents, chlorination agents, and fluorination agents, and control the reaction conditions, such as temperature, pressure, and catalyst, to achieve precise substitution and obtain the target product. However, on the road of synthesis, it is necessary to carefully observe the reaction process and product purity to prevent side reactions from disturbing it.
In short, 4-bromo-1-chloro-3,5-difluorobenzene has important uses in many fields such as medicine, materials, and pesticides, and plays a key role in the development of chemical synthesis and related industries.
What are the synthesis methods of 4-Bromo-1-Chloro-3,5-Difluorobenzene?
The synthesis method of 4-bromo-1-chloro-3,5-difluorobenzene is an important topic in the field of organic synthesis. To make this compound, there are several common ways as follows.
First, fluorobenzene derivatives are used as starting materials. A suitable fluorobenzene can be selected first, and bromine and chlorine atoms are introduced through halogenation reaction. For example, under specific reaction conditions, fluorobenzene is reacted with brominating reagents and chlorination reagents separately. Control factors such as reaction temperature, time and reagent dosage to accurately locate bromine and chlorine atoms to the target position. This process requires fine control of the reaction conditions, because the selectivity of the halogenation reaction is extremely critical. If the reaction conditions are improper, it is easy to form polyhalogenated by-products, which affects the purity and yield of the products.
Second, fluorine, bromine and chlorine substituents can also be gradually constructed from the benzene ring. First, a halogen atom is introduced through the electrophilic substitution reaction of benzene, and then the remaining halogen atoms and fluorine atoms are introduced in turn by nucleophilic substitution or other suitable reactions. This strategy requires clever design of the reaction sequence, taking into account the influence of each substituent on the subsequent reaction. If the halogen atom has been introduced, it will change the electron cloud density of the benzene ring, which in turn affects the activity and selectivity of the subsequent substitution reaction.
Or, aromatics containing specific substituents are used as raw materials and synthesized by functional group conversion. Aromatic hydrocarbons containing suitable substituents are prepared first, and then these substituents are converted into fluorine, bromine, and chlorine atoms through a series of reactions. This process requires familiarity with various functional group conversion reactions to ensure that the reaction is efficient and selective.
There are various methods for synthesizing 4-bromo-1-chloro-3,5-difluorobenzene, and each method has its own advantages and disadvantages. In practical applications, it is necessary to comprehensively consider various factors such as the availability of raw materials, the feasibility of reaction conditions, and the requirements of product purity, and carefully choose the appropriate synthesis path.
What is the market price of 4-Bromo-1-Chloro-3,5-Difluorobenzene?
4-Bromo-1-chloro-3,5-difluorobenzene is one of the organic compounds. Its market price is difficult to say in a word, and it depends on many factors.
The first one to bear the brunt is the state of supply and demand. If there are many people in the market who want it, but there are few people who supply it, the price will rise; conversely, if the supply exceeds the demand, the price may decline. For example, if at some point, the demand for materials containing this compound in the electronics industry increases sharply, and manufacturers compete for it, the price will skyrocket.
Furthermore, the price of raw materials also has a great impact. If the price of bromine, chlorine, fluorine and other raw materials required for the synthesis of this compound is too high, the cost of 4-bromo-1-chloro-3,5-difluorobenzene will rise, and its price in the market will also rise. If bromine production decreases sharply due to changes in origin, and the price is high, the price of this compound as raw material will also rise.
The simplicity and cost of the process are also key. If the synthesis method is complicated, special equipment is required, many steps are required, and the yield is not high, the cost will be high, and the market price will also be high. On the contrary, if a new process with convenience and efficiency comes out, the cost will be reduced, and the price will also drop.
In addition, the state of market competition cannot be ignored. If there are many competitors competing for profits, there may be price cuts to seek the market; if there are few competitors and they dominate, the price can be determined independently.
In summary, the market price of 4-bromo-1-chloro-3,5-difluorobenzene, such as the changing situation, is affected by various factors such as supply and demand, raw materials, processes, and competition. To determine its price, we must carefully consider the current market conditions.
What to pay attention to when storing and transporting 4-Bromo-1-Chloro-3,5-Difluorobenzene
4-Bromo-1-chloro-3,5-difluorobenzene is an organic compound, and its storage and transportation should be handled with caution.
When storing, choose the first environment. It should be placed in a cool, dry and well-ventilated place. This compound is quite sensitive to heat, and high temperature can easily cause it to decompose or cause dangerous reactions, so it should be kept away from fire and heat sources. If stored in a place with direct sunlight, light may induce photochemical reactions and cause it to deteriorate, so it should be stored in a place protected from light.
Furthermore, the choice of container is also crucial. It is advisable to use a container with good sealing performance to prevent the compound from coming into contact with air. It may react with oxygen, water vapor and other components in the air. It is also essential to choose a container with suitable materials to avoid chemical reactions between compounds and container materials, damage to the container, and even leakage.
When transporting, safety protection is the top priority. Be sure to ensure that the packaging is tight and stable to prevent package damage due to collision and vibration during transportation. The handling process should be handled with care and should not be handled brutally.
The environment of the transportation vehicle should also be controlled. Appropriate temperature and humidity should be maintained, and other potentially dangerous chemicals should be kept away to prevent mutual reaction. Transportation personnel should also be familiar with the characteristics of this compound and emergency treatment methods. In case of leakage and other accidents, they can be properly disposed of in time to avoid the expansion of harm.
Only by strictly following the specifications during storage and transportation can the safety of 4-bromo-1-chloro-3,5-difluorobenzene be ensured and potential risks and hazards be avoided.