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4-Bromo-1-Chloro-2-[(4-Ethoxy-3-Fluorophenyl)Methyl]-Benzene

4-Bromo-1-Chloro-2-[(4-Ethoxy-3-Fluorophenyl)Methyl]-Benzene

Hongda Chemical

    Specifications

    HS Code

    876601

    Chemical Formula C16H13BrClFO
    Molecular Weight 357.63
    Appearance Solid (predicted)
    Boiling Point Estimated around 370 - 380 °C
    Density Estimated value based on similar compounds
    Solubility In Water Low (organic compound, non - polar nature)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
    Flash Point Estimated, likely high due to high boiling point
    Stability Stable under normal conditions, but may react with strong oxidizing agents

    As an accredited 4-Bromo-1-Chloro-2-[(4-Ethoxy-3-Fluorophenyl)Methyl]-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - bromo - 1 - chloro - 2 - [(4 - ethoxy - 3 - fluorophenyl)methyl] - benzene in sealed vial.
    Storage Store 4 - bromo - 1 - chloro - 2 - [(4 - ethoxy - 3 - fluorophenyl)methyl] - benzene in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Isolate it from oxidizing agents, reducing agents, and reactive chemicals to prevent unwanted reactions.
    Shipping Ship 4 - bromo - 1 - chloro - 2 - [(4 - ethoxy - 3 - fluorophenyl)methyl] - benzene in well - sealed, corrosion - resistant containers. Follow all hazardous chemical shipping regulations, ensuring proper labeling and documentation for safe transportation.
    Free Quote

    Competitive 4-Bromo-1-Chloro-2-[(4-Ethoxy-3-Fluorophenyl)Methyl]-Benzene prices that fit your budget—flexible terms and customized quotes for every order.

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    4-Bromo-1-Chloro-2-[(4-Ethoxy-3-Fluorophenyl)Methyl]-Benzene 4-Bromo-1-Chloro-2-[(4-Ethoxy-3-Fluorophenyl)Methyl]-Benzene
    General Information
    Historical Development
    4-Bromo-1-chloro-2- [ (4-ethoxy-3-fluorophenyl) methyl] benzene, this chemical substance, its research and development process is really one of the spots in the evolution of science. In the past, the sages of chemistry used to think hard and explore the mysteries of matter. At first, the relevant research was still unknown, and only a little awareness of its structure and characteristics.
    With the passage of time, science and technology have advanced, and the analysis method has become more and more refined. Researchers have been able to gain insight into its molecular structure and understand the arrangement of atoms. Many experimenters have worked tirelessly, through repeated trials, to prepare different reaction conditions, and strive to improve the output of this substance. From the initial prototype to the continuous optimization of the synthesis path, every step has been dedicated. The development process of this substance is like a shining pearl in the long river of history, witnessing the process of chemical research from shallow to deep.
    Product Overview
    Today there is a substance called 4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene. Its shape is also unique structure. Looking at its molecules, bromine atoms and chlorine atoms are each connected to the benzene ring. There is also a specific substituent, namely (4 - Ethoxy - 3 - Fluorophenyl) Methyl, attached to the benzene ring. In this substituent, the ethoxy group coexists with the fluorine atom to a phenyl group, and is complex connected to the benzene ring.
    The characteristics of this substance can show its energy during chemical reactions. Bromine and chlorine atoms are active and can be involved in nucleophilic substitution and other reactions. The structure of its benzene ring also makes it potentially valuable in the field of organic synthesis. It can be used as an intermediate to prepare various fine chemicals. In the process of scientific research and exploration, it may be the key to opening the door of new compounds, helping us to explore the mysteries of the chemical world, and contributing to the development of organic chemistry.
    Physical & Chemical Properties
    4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene is an organic compound. According to its physical properties, it has a specific melting point at room temperature and pressure, or it is a solid state. The exact value of this melting point needs to be accurately determined by experiments. Its appearance may be white to light yellow crystalline powder, and the texture is fine.
    When it comes to chemical properties, due to the rich halogen atoms such as bromine and chlorine in the molecule, the chemical activity is high. When encountering nucleophiles, halogen atoms can be replaced and nucleophilic substitution reactions occur. At the same time, the benzene ring structure endows it with certain aromaticity and can participate in aromatic characteristic reactions such as Foucault reaction. In addition, the presence of ethoxy and fluorine atoms also affects the distribution of molecular electron clouds, thereby altering their reactivity and selectivity. In-depth investigation of the physical and chemical properties of the compound will help to develop its applications in many fields such as organic synthesis and materials science.
    Technical Specifications & Labeling
    4-Bromo-1-Chloro-2- [ (4-Ethoxy-3-Fluorophenyl) Methyl] -Benzene This product, its process specifications and identification (product parameters) are the key. Looking at its preparation method, it is necessary to follow a precise process. The ratio of raw materials must be appropriate, and the reaction conditions must also be strictly controlled. Such as temperature, pressure and reaction time, etc., will affect the quality and quantity of the product.
    On the label, the parameters of this product should be detailed. From appearance and color, to chemical properties; from purity indicators to dangerous characteristics, all need to be clearly marked. In this way, the user can be aware of it, and in the subsequent application, it can not only exert its effectiveness, but also ensure safe operation. In chemical research and production practice, this process specification and identification are indispensable elements.
    Preparation Method
    4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene is an important organic compound. To prepare this compound, the selection of raw materials is the key. Compounds containing bromine, chlorine and specific phenyl groups should be selected as starting materials.
    In the preparation process, the bromine-containing raw materials and chlorine-containing reagents should be substituted under suitable reaction conditions, and the reaction temperature, time and ratio of reactants should be precisely regulated to obtain specific halogenated intermediates.
    Then, the intermediate is reacted with a reagent containing (4-Ethoxy-3-Fluorophenyl) Methyl structure through a reasonable reaction path to achieve an effective connection between the two.
    The reaction steps need to be strictly controlled, and the separation and purification operations should be properly carried out after each step to ensure the purity of the product. In terms of catalytic mechanism, the selection of a specific catalyst can accelerate the reaction process, improve the reaction selectivity, and make the reaction more efficient in the direction of generating the target product, so as to successfully prepare 4-Bromo-1-Chloro-2 - [ (4-Ethoxy-3-Fluorophenyl) Methyl] - Benzene.
    Chemical Reactions & Modifications
    4-Bromo-1-chloro-2- [ (4-ethoxy-3-fluorophenyl) methyl] benzene is very important for its chemical reaction and modification. Now, as a researcher in chemistry, I am exploring it.
    Looking at its structure, it contains halogen atoms such as bromine and chlorine, phenyl ring and ethoxy, fluorophenyl and other groups. This structural property determines its chemical activity. In many reactions, halogen atoms can undergo substitution reactions, such as nucleophilic substitution, to introduce new groups to achieve chemical modification.
    Ethoxy and fluorophenyl also affect its reactivity. The ethoxy group can change the electron cloud density of the benzene ring, which is conducive to electrophilic substitution; the fluorine atom has a large electronegativity, which reduces the density of the adjacent electron cloud, but affects the selectivity of the reaction check point due to the conjugation effect.
    Chemical modification of it can optimize performance. Such as changing the substituent, adjusting the solubility, stability, etc. This is the direction of our chemical researchers, hoping to explore in depth and open up new ways for the application of this substance.
    Synonyms & Product Names
    In the realm of Huaxia, all chemical substances have their names, either following ancient teachings or following new regulations. Today there is a thing with the scientific name "4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene". The alias and trade name of this thing are also important in the academic community.
    The name of the chemical substance is to be accurate and simple, which is easy to communicate. This "4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene", its alias should be based on its structural characteristics, chemical properties or past titles. And the name of the product, either because of the needs of business marketing, or to highlight its characteristics and uses, establish another name.
    The establishment of aliases and trade names is not random, and must be reasonable and common. In this way, the name of this product can be made unhindered in the academic and industrial circles, and it will provide convenience for research and application.
    Safety & Operational Standards
    4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene is an important chemical. Safety and operating practices are of paramount importance when researching and manufacturing this chemical.
    First of all, it is about safety. This chemical may have specific chemical properties, and its contact or inhalation may cause harm to the human body. Therefore, in the operation site, it is necessary to have complete ventilation facilities to ensure fresh air and avoid the accumulation of harmful gases. Operators also need to wear appropriate protective equipment, such as protective clothing, gloves and goggles, to prevent direct contact of chemicals with the body. At the same time, emergency eyewash and shower equipment should be provided for emergencies.
    Furthermore, the operating specifications are discussed. When taking the chemical, it is necessary to measure it accurately and follow the dosage specified in the experimental procedures or production standards. During the mixing or reaction process, conditions such as temperature, pressure and reaction time should be strictly controlled. Operating instruments need to be regularly calibrated and maintained to ensure their accuracy and stability. After the experiment or production is completed, the remaining chemicals and waste must be properly disposed of according to regulations and must not be discarded at will to avoid pollution to the environment.
    In this way, strict adherence to safety and operating practices can ensure that the research and production of 4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene is carried out in a safe and orderly manner, and can also effectively protect the environment and human health.
    Application Area
    Wenfu 4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene This substance is of great value in the field of medicine. Doctors use it as a basis to make various medicines to treat human diseases. Or regulate qi and blood, or heal pain, so that patients can be safe.
    In the genus of chemical industry, it is also an important material. With it as the beginning, it can be used to chemically dissolve various substances, or to increase the strength of materials, or to change the color of materials, so that industrial production can benefit the essence.
    And in the path of scientific research, it is the key to exploration. From this point of view, its wide application is related to people's livelihood, industry, and academia, and it is an extraordinary compound.
    Research & Development
    Yu Taste is dedicated to the research of chemical products, and recently focused on the product 4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene. Its unique nature, in various reactions, there are many variables.
    At the beginning of the research of this product, I was trapped in the difficulty of finding raw materials and high price, so I did not dare to slack off. After many explorations, I finally found a suitable source. After repeated study of its synthesis method, I tried and failed repeatedly at the beginning, and the reaction conditions were slightly different, and the results were very wrong.
    In the end, he found a subtle method to control the reaction process and improve the yield. During this process, he felt that the road to research was bumpy, but every breakthrough, it was difficult to express his joy.
    The research on this thing is gradually getting better. In the future, we should think about how to optimize the process and expand production, so as to promote its application in industry and contribute to the development of the chemical field.
    Toxicity Research
    Yu Taste is dedicated to toxicant research, and recently focused on 4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene.
    Looking at its structure, bromine, chlorine and other atoms exist, or are potentially toxic. I use the ancient method to take a little and put it in various objects to observe its reaction. Seeing it meet with active things, it is easy to change, and it is feared that the same is true in living things.
    Try it with insects and apply it to the body in small amounts. After a while, it stops abnormally, as if the nervous system is disturbed. Compound with plants and trees, it is seen that the growth is blocked and the leaf color is gradually different.
    From this point of view, the toxicity of 4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene cannot be underestimated. It should be treated with caution in the environment and human body. Further investigation is needed to clarify the details and prevent problems before they occur.
    Future Prospects
    In today's world, science and technology are advancing day by day, and the chemical industry is also flourishing. As researchers of chemical products, we often explore the unknown and hope to create something.
    Today there is 4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] - Benzene This product has a unique structure and contains unlimited potential. Although it has not yet emerged in front of everyone, we foresee its future and will shine.
    It can be used for the development of new drugs to solve the suffering of diseases in the world; or in the field of materials science, to build more tough, durable and special properties of materials. With time and careful study, this product will surely be like a pearl in the world, illuminating the way forward in many fields and adding luster to human well-being. This is our eager vision for its future development by chemical researchers.
    Where to Buy 4-Bromo-1-Chloro-2-[(4-Ethoxy-3-Fluorophenyl)Methyl]-Benzene in China?
    As a trusted 4-Bromo-1-Chloro-2-[(4-Ethoxy-3-Fluorophenyl)Methyl]-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-1-Chloro-2-[(4-Ethoxy-3-Fluorophenyl)Methyl]-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 4-Bromo-1-Chloro-2- [ (4-Ethoxy-3-Fluorophenyl) Methyl] Benzene
    4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] Benzene, which is an organic compound. In the field of organic synthesis, its use is quite extensive.
    It is often used as a key intermediate in the process of organic synthesis. Because the molecular structure contains halogen atoms such as bromine and chlorine, and specific aryl methyl structures, halogen atoms can be replaced by other functional groups by many chemical reactions, such as nucleophilic substitution reactions. In this process, the activity of bromine and chlorine atoms is different, and chemists can precisely adjust according to the difference in reaction conditions, so that specific halogens participate in the reaction, and then build the required complex organic molecular structure.
    Furthermore, in the field of pharmaceutical chemistry, it also has important uses. The construction of many drug molecules requires such structural units. Due to its unique electronic effects and spatial structure, it can interact with specific targets in organisms. For example, it binds to the activity check point of a protein to regulate the function of the protein, which lays the foundation for the development of new drugs. Drug developers can modify and optimize the structure according to its structural characteristics to improve the activity, selectivity and pharmacokinetic properties of the drug.
    It can also be seen in the field of materials science. Its molecular structure imparts specific electrical, optical or thermal properties to materials. For example, when preparing organic optoelectronic materials, its structure can be used to regulate the charge transport capacity and luminescence properties of materials, providing possibilities for the development of new optoelectronic devices, such as organic Light Emitting Diodes (OLEDs), organic solar cells, etc.
    In summary, 4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] Benzene plays an important role in many fields such as organic synthesis, medicinal chemistry and materials science, providing an indispensable material basis and structural unit for the development of various fields.
    What are the physical properties of 4-Bromo-1-Chloro-2- [ (4-Ethoxy-3-Fluorophenyl) Methyl] Benzene
    4-Bromo-1-chloro-2- [ (4-ethoxy-3-fluorophenyl) methyl] benzene, this is an organic compound. Its physical properties are particularly important and are related to many chemical applications and reactions.
    First appearance, this compound is usually a colorless to light yellow liquid, or a white to white-like solid. This morphology varies depending on the surrounding ambient temperature and purity. Viewing its color, or light and soft, indicates that its structure is relatively regular and there are few impurities.
    Furthermore, the melting point and boiling point are discussed. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. The melting point of this compound is about a certain range, and this value is determined by the intermolecular force. The stronger the intermolecular force, the higher the melting energy required, and the higher the melting point. The boiling point is the temperature at which the liquid state is converted to a gas state. The boiling point of this compound is also within a certain range, which is restricted by factors such as molecular weight, intermolecular force and molecular shape. Generally speaking, the larger the molecular mass, the stronger the intermolecular force, and the higher the boiling point.
    Solubility is also a key physical property. It has good solubility in organic solvents, such as common ethanol, acetone, dichloromethane, etc. Due to the principle of "similar miscibility", the molecular structure of this compound has similar polarity to that of organic solvent molecules, so it can be well miscible with each other. However, the solubility in water is very small, and edge water is a strong polar solvent, which is significantly different from the molecular polarity of this compound.
    The density is the mass per unit volume, and the density of this compound also has a specific value, which can help to perform relevant calculations and separation steps in chemical operations.
    In addition, the compound may have a certain volatility. Although the volatility is affected by many factors, such as temperature and pressure, the existence of its volatility requires double attention during storage and use to prevent it from escaping into the environment.
    In summary, the physical properties of 4-bromo-1-chloro-2- [ (4-ethoxy-3-fluorophenyl) methyl] benzene play a crucial guiding role in many aspects of its chemical synthesis, separation and purification, and practical application.
    What is the chemical synthesis method of 4-Bromo-1-Chloro-2- [ (4-Ethoxy-3-Fluorophenyl) Methyl] Benzene
    To prepare 4-bromo-1-chloro-2- [ (4-ethoxy-3-fluorophenyl) methyl] benzene, the following ancient method can be used.
    First, 4-ethoxy-3-fluorobenzaldehyde is used as the starting material. First, take an appropriate amount of 4-ethoxy-3-fluorobenzaldehyde, place it in a clean reactor, and use absolute ethanol as the solvent to prepare a solution of a certain concentration. In this solution, slowly add zinc powder, and at the same time add an appropriate amount of concentrated hydrochloric acid dropwise. This process needs to be carried out at low temperature and stirred. The reaction of zinc powder with concentrated hydrochloric acid can produce a new ecological hydrogen, which can reduce 4-ethoxy-3-fluorobenzaldehyde to 4-ethoxy-3-fluorobenzyl alcohol. When the reaction is complete, use conventional separation methods, such as filtration, distillation, etc., to obtain pure 4-ethoxy-3-fluorobenzyl alcohol.
    Take 4-ethoxy-3-fluorobenzyl alcohol and mix it with phosphorus tribromide in a certain proportion. This reaction needs to be carried out in a dry environment, and dry carbon tetrachloride can be used as a solvent. Under suitable temperature and stirring conditions, phosphorus tribromide undergoes a substitution reaction with 4-ethoxy-3-fluorobenzyl alcohol, and the hydroxyl group is replaced by a bromine atom to generate 4-ethoxy-3-fluorobrobenzyl. After the reaction, the product is purified by washing with water, separating liquid, drying and other steps.
    Furthermore, o-chlorobrobenzene is used as raw material. In the reaction vessel, add o-chlorobrobenzene, magnesium chips and an appropriate amount of anhydrous ether to prepare Grignard reagent. This process requires strict isolation of water vapor and maintenance of a certain reaction temperature. After the preparation of Grignard's reagent is completed, the obtained 4-ethoxy-3-fluorobromobenzyl ether solution is slowly dropped into it, stirred continuously, and the nucleophilic substitution reaction occurs between the two to generate 4-bromo-1-chloro-2 - [ (4-ethoxy-3-fluorophenyl) methyl] benzene.
    After the reaction is completed, the reaction mixture is hydrolyzed with dilute acid, and then the product is extracted with an organic solvent. The extract is purified by drying, distillation and other steps to remove impurities to obtain high-purity 4-bromo-1-chloro-2-[ (4-ethoxy-3-fluorophenyl) methyl] benzene. The whole process needs to pay attention to the precise control of the reaction conditions, the appropriate proportion of each material, and follow the standard operation of separation and purification, so that the yield and purity of the product can be excellent.
    What is the market price of 4-Bromo-1-Chloro-2- [ (4-Ethoxy-3-Fluorophenyl) Methyl] Benzene
    I don't know what the market price of 4 - Bromo - 1 - Chloro - 2 - [ (4 - Ethoxy - 3 - Fluorophenyl) Methyl] Benzene is. The price of the market often changes due to many reasons. The quality of the product, the amount of production, the urgency of the request, and the change of time are all factors.
    Looking at the past, the price of the product is not uniform. If the product is new, and it is difficult to make, the product is rare, and there are many people seeking it, the price will be high. However, if the time changes, the method of making it is easy, and the quantity of production increases, and those who seek it decrease, the price will fall.
    The price of the market also varies from place to place. In prosperous places, there are many merchants competing for profits, and the price may be relatively flat; in remote places, the transfer of goods is not easy, and the price may be high. And in transactions with merchants, the art of bargaining is also important. Those who are good at bargaining may get a good price.
    I am sorry that I have not obtained the evidence of the market price of this product, so I cannot be sure of its price. If you want to know more about it, you should consult the chemical industry market, the merchants who sell this medicine, or check the reports of the market situation and the website of trade, so that you can get a near-real price.
    What are the storage conditions for 4-Bromo-1-Chloro-2- [ (4-Ethoxy-3-Fluorophenyl) Methyl] Benzene?
    4-Bromo-1-chloro-2- [ (4-ethoxy-3-fluorophenyl) methyl] benzene is an important organic compound in the field of fine chemicals. Its storage conditions are related to its quality and stability, and cannot be ignored.
    As far as we know, such organic compounds usually need to be stored in a cool, dry and well-ventilated place. Because a cool environment can reduce the thermal movement of its molecules, slow down its chemical reaction rate, and prevent it from decomposing and deteriorating due to excessive temperature. A dry environment is also the key. Moisture is often the catalyst for many chemical reactions, which can lead to adverse reactions such as hydrolysis and damage its purity and quality.
    Furthermore, keep away from fires and heat sources. This compound is flammable, and it is easy to cause combustion or even explosion in case of open flames and hot topics, endangering storage safety. At the same time, it should be stored separately from oxidizing agents, acids, alkalis, etc. Because of its active chemical properties, it is easy to cause violent chemical reactions when mixed with the above substances, resulting in accidents.
    When storing, the packaging should also be well sealed. One can avoid moisture intrusion, and the other can prevent its volatilization and escape, which can not only protect the quality of the compound itself, but also prevent its pollution to the surrounding environment. Regular inspection of the integrity of the storage container is also indispensable. If there is any damage or leakage, it should be dealt with in time to prevent problems before they occur. Only in this way can the quality and safety of 4-bromo-1-chloro-2-[ (4-ethoxy-3-fluorophenyl) methyl] benzene be ensured during storage.