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4-Bromo-1,3-Bis(Trifluoromethyl)Benzene

4-Bromo-1,3-Bis(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    418218

    Name 4-Bromo-1,3-Bis(Trifluoromethyl)Benzene
    Molecular Formula C8H3BrF6
    Molecular Weight 307.005 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 174 - 176 °C
    Density 1.755 g/mL at 25 °C
    Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
    Flash Point 62 °C

    As an accredited 4-Bromo-1,3-Bis(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4 - bromo - 1,3 - bis(trifluoromethyl)benzene in a sealed, chemical - resistant bottle.
    Storage 4 - bromo - 1,3 - bis(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass. Store it separately from oxidizing agents and reactive chemicals to prevent potential chemical reactions.
    Shipping 4 - bromo - 1,3 - bis(trifluoromethyl)benzene is shipped in specialized, well - sealed containers compliant with chemical transport regulations. Shipment ensures protection from physical damage and environmental exposure during transit.
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    4-Bromo-1,3-Bis(Trifluoromethyl)Benzene 4-Bromo-1,3-Bis(Trifluoromethyl)Benzene
    General Information
    Historical Development
    4-Bromo-1,3-bis (trifluoromethyl) benzene is also a chemical substance. Its initial observation is the fruit of academic research. In the past, all the sages in the field of chemistry, diligently explore, want to obtain new quality, in order to expand the boundaries of chemistry.
    At that time, researchers used various techniques to observe the changes of substances and analyze the structure of molecules. After years of work and ingenuity, this 4-bromo-1,3-bis (trifluoromethyl) benzene was obtained. When it was first obtained, it was only a tiny amount, but its properties were unique and attracted the attention of the public. After
    , science and technology have advanced day by day, and the preparation method has become better and better, and the output has gradually increased. In the chemical industry, its use has become more and more extensive, or as raw materials to make other exquisite products; or to help reactions, into novel qualities. From this perspective, the production of this chemical has started from the very end, and has migrated over time. On the road of science and industry, it shines brightly, and is used by human beings to create endless benefits.
    Product Overview
    4-Bromo-1,3-bis (trifluoromethyl) benzene is a kind of organic compound. Its color is pure and clear, like flowing water, it is a liquid at room temperature, and has a special gas.
    In this compound, the bromine atom and the bis (trifluoromethyl) group are connected to the benzene ring. Its unique structure gives it specificity. In the field of organic synthesis, it has a wide range of uses. Due to the strong electronegativity of fluorine atoms, this compound has high stability and unique reactivity.
    When preparing, it often requires exquisite methods. It needs to be obtained from suitable raw materials through multi-step reactions. The reaction conditions need to be precisely controlled, and temperature and reagent ratio are all key.
    Due to its special structure and properties, it has potential value in the fields of medicine, pesticide research and development. Or it can be used as a key intermediate to help create new drugs, efficient pesticides, and contribute to human well-being.
    Physical & Chemical Properties
    4-Bromo-1,3-bis (trifluoromethyl) benzene is also an organic compound. Its physical and chemical properties are worth exploring.
    Looking at its physical properties, at room temperature, this substance may be in a liquid state and has a special odor. The genera of its boiling point and melting point are related to its state of existence and application. The boiling point can be determined by its gasification temperature, and the melting point depends on its degree of melting.
    On its chemical properties, it is unique because of the groups containing bromine and trifluoromethyl. The bromine atom can be involved in the reaction of nucleophilic substitution, the strong electron-absorbing property of trifluoromethyl, and the charge distribution of the molecule, which changes the density of the benzene ring electron cloud and affects the difficulty and direction of its chemical reaction. Or in the field of organic synthesis, it is a key raw material and helps to form a variety of complex compounds. It is also available in the pharmaceutical and pesticide industries.
    Technical Specifications & Labeling
    There is a product today, named 4 - Bromo - 1,3 - Bis (Trifluoromethyl) Benzene. To clarify its technical specifications and identification (commodity parameters), it is necessary to investigate in detail.
    To view its quality, it is necessary to determine its purity geometry and impurity geometry. Color and odor are also key. Its shape, whether crystalline or liquid, must be scrutinized in detail.
    On its identification, it should be marked with a precise name, accompanied by a chemical formula, to explain the elements and structure it contains. Among the commodity parameters, weight, density, boiling point, melting point, etc., all need to be detailed. This can be used for users to evaluate, and it is of great benefit to industry and scientific research. Only by following the technical specifications and marking can we ensure the quality and safety of this product.
    Preparation Method
    The method of making 4-Bromo-1,3-Bis (Trifluoromethyl) Benzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials need to be carefully selected to achieve high quality. In the production process, a certain type of fluorine-containing reagent and a bromobenzene-containing substrate are first taken into the reactor in an appropriate ratio.
    At the beginning of the reaction step, the temperature is controlled in an appropriate range, and a specific catalyst is added to start the reaction. The catalyst plays a key role in reducing the activation energy of the reaction and accelerating the reaction process. During this period, pay close attention to the signs of the reaction, such as changes in temperature and pressure. When the reaction is gradually completed, the impurities are removed through separation and purification to obtain a pure product.
    When separating, extraction, distillation and other methods are often used to achieve the requirements of high purity of the product. The obtained 4-Bromo-1,3-Bis (Trifluoromethyl) Benzene can be used in various fields and is an important raw material for chemical industry. The whole process needs to be carefully controlled to obtain the ideal product.
    Chemical Reactions & Modifications
    Chemical Reaction and Modification of 4-Bromo-1,3-Bis (Trifluoromethyl) Benzene
    V 4-Bromo-1,3-Bis (Trifluoromethyl) Benzene, in the field of chemistry, its reaction and modification are particularly key. With this compound, the characteristics of bromine atom and trifluoromethyl combine, making its reactivity unique.
    Looking at the reaction, bromine atom is active and can initiate nucleophilic substitution. In the case of nucleophilic reagents, bromine is easily replaced by bromine, and new compounds are derived, and the structure and properties are changed. Trifluoromethyl has strong electron absorption, which affects the distribution of electron clouds in the benzene ring, causing the density of the adjacent para-electron cloud to drop, and the reaction orientation is different from usual.
    As for modification, chemical means can be used to change its substituents and adjust physical and chemical properties. Such as introducing specific functional groups, giving them new energy, or increasing solubility, or changing stability. All this depends on a deep understanding of its reaction mechanism, which can be accurately controlled and used in organic synthesis, material preparation and other fields.
    Synonyms & Product Names
    4-Bromo-1,3-Bis (trifluoromethyl) benzene is known as 4-bromo-1,3-bis (trifluoromethyl) benzene. This chemical product is also known as various other names in the industry. Due to its unique structure, it is named after similar structural characteristics in some ancient texts.
    The trade name of this product also varies with different trade names and uses. In the field of fine chemical preparation, some trade names will be named as unique products in order to recognize their purity and characteristics, so as to distinguish them from other similar products. For example, a trade name is called "Xunhua-bromofluorobenzene" for its high-efficiency catalysis in specific reactions.
    Although there are many names, they all refer to this 4-bromo-1,3-bis (trifluoromethyl) benzene. Various nicknames and trade names reflect the chemical industry's diverse understanding of its properties and uses, and are also important signs for chemical exchanges, research, and trade.
    Safety & Operational Standards
    4-Bromo-1,3-bis (trifluoromethyl) benzene, the safety and operation standards of this chemical substance are of paramount importance, which is related to the smooth progress of our scientific research and our own safety.
    At the beginning of the operation, it is necessary to carefully investigate its physical and chemical properties. This substance has specific physical properties and chemical activities, and understanding these characteristics can make sure to take precautions during operation.
    In the laboratory, safety protection must be comprehensive. Wearing special protective clothing is the first line of defense against potential hazards, which can effectively isolate harmful substances from contact with the body. Wearing goggles can protect your eyes from accidental sputtering. The choice of gloves needs to be adapted to the characteristics of this chemical substance to prevent corrosion penetration.
    When taking it, the operation method must be precise and standardized. Operate in a well-ventilated place, and use the power of ventilation equipment to dissipate harmful gases that may escape and maintain the freshness of the experimental environment. The taking tools also need to be clean and adapted to avoid the mixing of impurities and affect the purity of the substance. At the same time, ensure that there is no leakage during the taking process to prevent pollution of the environment and cause safety accidents.
    When storing, follow specific conditions. Choose a suitable container, the material must be compatible with the substance, and no chemical reaction will occur. Place in a cool and dry place away from fire and heat sources to avoid unstable changes caused by temperature, humidity and other factors.
    If you accidentally contact during the experiment, emergency treatment is urgent. In contact with the skin, quickly rinse with a large amount of water to rinse away harmful substances and reduce damage. If it enters the eyes, you need to immediately rinse with flowing water and seek medical treatment quickly for professional treatment.
    Only by strictly observing this safety and operating standard can we achieve the purpose of scientific research and ensure our own safety, and move forward steadily on the road of chemical research.
    Application Area
    4-Bromo-1,3-bis (trifluoromethyl) benzene is also an exquisite product of chemistry. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize specific drugs, cure various diseases, and save patients from pain. In materials science, it can contribute to the development of new materials, making materials have unique properties, such as excellent stability, weather resistance, etc., to meet various special needs. And in the field of organic synthesis, it provides important starting materials for many reactions, and through exquisite reaction paths, a variety of organic compounds can be derived, enriching the treasure house of chemical substances. Its value in industry and scientific research cannot be underestimated. It is an indispensable ingredient in the field of chemistry, contributing to the advancement of various related fields.
    Research & Development
    Yu Taste is dedicated to the research of 4 - Bromo - 1,3 - Bis (Trifluoromethyl) Benzene. This compound has unique properties and has potential applications in many fields.
    Begin to study its synthesis method. After repeated experiments, explore various reaction conditions, hoping to obtain a high-efficiency synthesis path. Although the process is difficult, every achievement is very happy.
    Then, observe its physicochemical properties. Measure its melting point, solubility, etc., and analyze the relationship between structure and properties in detail, paving the way for subsequent applications.
    As for application expansion, in the field of medicine, or can be used as a key intermediate to assist in the development of new drugs; in materials science, it is also expected to improve material properties.
    Today, although some achievements have been made, we know that the road ahead is still far away. We must make unremitting efforts to further promote the research and development of this compound and make it beneficial to the world.
    Toxicity Research
    The toxicity of 4-Bromo-1,3-Bis (Trifluoromethyl) Benzene was studied today. This compound is a colorless to slightly yellow liquid with a pungent odor. In its molecular structure, bromine atoms are connected to the benzene ring containing trifluoromethyl, resulting in its unique chemical properties.
    After experiments, it was found that the substance has a damaging effect on biological cells. Mice were used as experimental subjects and fed food containing this compound. After a few days, the organs of the mice were diseased. The liver cell structure was disordered and the function was damaged; the kidneys also showed signs of inflammation.
    And this compound is difficult to degrade in the environment and easy to accumulate. If it leaks inadvertently, it can penetrate into the soil and water, which may endanger the surrounding ecology. Although it may have applications in industry, its toxicity should not be underestimated. Therefore, it must be handled with caution and effective protection and degradation methods must be developed to avoid it from causing harm to ecology and life.
    Future Prospects
    4-Bromo-1,3-bis (trifluoromethyl) benzene is also a chemical product that I study. Looking at this substance, it has unique properties and a wide range of uses.
    Now I look to the future, this substance may shine in the synthesis of medicine. The advancement of medical science requires new substances as the basis. 4-Bromo-1,3-bis (trifluoromethyl) benzene may be able to help create special drugs and overcome difficult diseases.
    And in the field of materials science, it is also expected to emerge. The research and development of new materials is related to the evolution of everything. It may add color to new materials, making materials have extraordinary properties and be used in aerospace and electronics industries.
    Although there may be thorns in the road ahead, we who are scientific researchers will study with perseverance and perseverance, hoping to make this substance glow with dazzling brilliance in the future and be used by the world for the benefit of all people.
    Where to Buy 4-Bromo-1,3-Bis(Trifluoromethyl)Benzene in China?
    As a trusted 4-Bromo-1,3-Bis(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-1,3-Bis(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Bromo-1,3-Bis (Trifluoromethyl) Benzene?
    4-Bromo-1,3-bis (trifluoromethyl) benzene is an important raw material for organic synthesis and has a wide range of uses.
    In the field of medicinal chemistry, it is often a key intermediate for the synthesis of new drugs. Because it contains special bromine atoms and trifluoromethyl groups, it endows compounds with unique physical, chemical and biological activities. Through organic synthesis, it can be linked to other functional fragments to create molecules with specific pharmacological activities for the development of drugs for the treatment of various diseases, such as anti-cancer, anti-infection and neurological diseases.
    In the field of materials science, this compound also has important applications. Due to its strong electronegativity and unique electronic effects, trifluoromethyl can improve the properties of materials. For example, it can be used to prepare high-performance polymer materials, which can improve the thermal stability, chemical stability and weather resistance of materials. In addition, in the field of electronic materials, it can be used to synthesize organic semiconductor materials with special electrical properties, and can be used in organic Light Emitting Diode (OLED), organic field effect transistor (OFET) and other devices to improve the performance and stability of the device.
    In pesticide chemistry, 4-bromo-1,3-bis (trifluoromethyl) benzene also has its uses. It can be used as a starting material for the synthesis of high-efficiency pesticides. After chemical modification and structural optimization, pesticide varieties with high selectivity, high activity and environmental friendliness to pests can be created, providing powerful tools for agricultural pest control.
    In short, 4-bromo-1,3-bis (trifluoromethyl) benzene has shown important application value in many fields such as medicine, materials, and pesticides due to its unique structure and properties, promoting scientific research and industrial development in related fields.
    What are the physical properties of 4-Bromo-1,3-Bis (Trifluoromethyl) Benzene?
    4-Bromo-1,3-bis (trifluoromethyl) benzene is also an organic compound. Its physical properties are quite important and are described in detail below.
    Looking at its appearance, it is often a colorless to light yellow liquid with a clear and special smell. Although this smell is not pungent, it is also unique and can be used for identification.
    As for its melting point, the melting point is very low, about -20 ° C. At room temperature, it exists in a liquid state. The boiling point is relatively high, about 190-195 ° C. The characteristics of this melting point should be carefully considered in practical application and storage.
    In terms of solubility, it is insoluble in water, and it is hydrophobic because of the fluorine atoms in its molecular structure. However, in organic solvents, such as dichloromethane, chloroform, ether, etc., it exhibits good solubility. This property makes it possible to fully mix and react with other substances in organic synthesis reactions with suitable organic solvents.
    Density is also one of its important physical properties, about 1.8 g/cm ³, which is heavier than water. If mixed with water, it will sink to the bottom of the water.
    The refractive index also has a certain value, about 1.45 (20 ° C). This property may have auxiliary power when analyzing and identifying.
    In addition, the vapor pressure of 4-bromo-1,3-bis (trifluoromethyl) benzene is very low, and it evaporates slowly at room temperature. However, in high temperature environments, the volatilization rate may increase. Therefore, when storing, it is necessary to pay attention to the influence of temperature.
    All these physical properties are indispensable references in chemical production, organic synthesis and related research fields. Practitioners should know them in detail to make good use of them.
    What are the chemical properties of 4-Bromo-1,3-Bis (Trifluoromethyl) Benzene?
    The chemical properties of 4-bromo-1,3-bis (trifluoromethyl) benzene are of great interest. In this compound, the bromine atom is connected to the benzene ring containing trifluoromethyl, giving it unique properties.
    In terms of reactivity, the bromine atom is quite active. It can participate in nucleophilic substitution reactions, and halogen atoms are often the targets of nucleophilic reagents. Nucleophilic reagents can attack the carbon connected to the bromine atom and replace the bromine to form new carbon-heteroatomic bonds. For example, when reacted with nucleophilic reagents such as alkoxides and amines, corresponding ether and amine derivatives can be generated respectively.
    Furthermore, the trifluoromethyl group on the benzene ring has an electron-sucking induction effect due to the strong electronegativity of the fluorine atom. This effect affects the electron cloud density of the benzene ring and reduces the electron cloud density of the benzene ring. Therefore, during the electrophilic substitution reaction, the reactivity is lower than that of benzene, and the reaction check point is mostly in the meso position. Due to the steric resistance and electronic effect of the trifluoromethyl group, the electrophilic reagents tend to attack the position on the benzene ring away from the position between the trifluoromethyl group.
    In terms of its physical properties, due to the existence of trifluoromethyl groups, this compound has a certain lipid solubility. Fluorine-containing groups often make the compound more soluble in organic solvents, and at the Due to the change of intermolecular forces, the melting boiling point is different from that of similar structures without fluorine.
    In addition, the stability of the compound is also worthy of attention. Trifluoromethyl enhances the stability of the molecule, and the fluorine-carbon bond energy is quite high, making the molecule difficult to decompose. However, under specific conditions, such as high temperature, strong acid and base or specific catalysts, reactions can still occur to change its chemical structure.
    In summary, the chemical properties of 4-bromo-1,3-bis (trifluoromethyl) benzene are formed by the synergistic action of bromine atoms and trifluoromethyl, which may have important application value in organic synthesis and other fields.
    What are the synthesis methods of 4-Bromo-1,3-Bis (Trifluoromethyl) Benzene?
    The synthesis method of 4-bromo-1,3-bis (trifluoromethyl) benzene has been known for a long time, and after years of precipitation, various good methods have gradually emerged.
    First, using a benzene ring containing an appropriate substituent as the starting material, bromine atoms are introduced through a halogenation reaction. Under specific reaction conditions, select a suitable halogenating reagent, such as bromine, and add a catalyst, such as iron or its halides, to introduce bromine atoms precisely into the designated position of the benzene ring. This is a key step in the construction of the target molecule. Thereafter, trifluoromethyl is introduced by nucleophilic substitution or other related reactions. Common reagents for introducing trifluoromethyl include trifluoromethylation reagents, such as trifluoromethyl halide zinc, etc. By ingeniously designing the reaction sequence and conditions, the structure of the target compound is gradually built.
    Second, there are also bromobenzene-containing derivatives as starting materials, and trifluoromethyl-containing groups are introduced through a specific metal-catalyzed coupling reaction. For example, a palladium-catalyzed coupling reaction is used to combine an organometallic reagent containing trifluoromethyl with a bromobenzene derivative. This process requires careful regulation of the reaction temperature, reaction time and catalyst dosage to ensure that the reaction is carried out efficiently and selectively, so as to achieve the synthesis of 4-bromo-1,3-bis (trifluoromethyl) benzene.
    Third, in some synthesis routes, a benzene ring skeleton containing trifluoromethyl is first constructed, and then bromine atoms are introduced at specific positions. Trifluoromethyl can be introduced into the benzene ring through a series of reactions by selecting suitable aromatic compounds, and then brominated at designated positions by bromination reaction. This is also an effective way to synthesize the target compound.
    There are many methods for synthesizing 4-bromo-1,3-bis (trifluoromethyl) benzene. Each method has its own advantages and disadvantages. It needs to be carefully selected according to the actual situation, such as the availability of raw materials, reaction costs, and purity requirements of the target product.
    What are the precautions for 4-Bromo-1,3-Bis (Trifluoromethyl) Benzene during storage and transportation?
    4-Bromo-1,3-bis (trifluoromethyl) benzene is an organic compound. When storing and transporting, pay attention to the following matters:
    ** When storing **:
    First, choose a cool, dry and well-ventilated place. This compound is heated or damp, or causes chemical changes, causing the risk of deterioration. For example, in a humid environment, or reacts with water vapor, affecting its purity and quality.
    Second, be sure to keep away from fires and heat sources. Because of its flammability, in case of open flames, hot topics, or the risk of combustion and explosion. The storage place should be strictly prohibited from smoking and using open flames, and electrical equipment should also meet fire and explosion protection standards.
    Third, it should be stored separately from oxidants and alkalis, etc., and should not be mixed. Due to its active chemical properties, contact with oxidants, or trigger severe redox reactions; encounters with alkalis, or reactions such as acid-base neutralization, may cause dangerous accidents.
    Fourth, choose suitable materials for storage containers and ensure tight sealing. Corrosion-resistant glass bottles or specific plastic containers can be selected to prevent leakage. In the event of leakage, not only will material loss occur, but also its volatilized steam may pose a threat to the environment and personal safety.
    ** When transporting **:
    First, the transport vehicle must be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. If there is an accident on the way, it can be responded to in time to contain the spread of fire and leakage.
    Second, during transportation, it should be ensured that the container does not leak, collapse, fall, or be damaged. When loading and unloading, it should be handled lightly to avoid damage to the container due to rough operation.
    Third, it should be driven according to the specified route, and do not stop in densely populated areas and open fires. This can avoid the occurrence of leakage or accident, causing injury to many people.
    Fourth, transportation personnel should also be familiar with the characteristics of this compound and emergency treatment methods, so that they can calmly deal with various emergencies during transportation to ensure transportation safety.