4-Bromo-1,2 - [ (difluoromethylene) dioxy] benzene, an organic compound. It has a wide range of uses and is very important in the field of organic synthesis.
In the field of medicinal chemistry, it is often used as a key intermediate. Due to its unique structure, it can participate in many chemical reactions and help build complex drug molecular structures. By reacting with other reagents, specific functional groups can be precisely introduced, thus laying the foundation for the synthesis of drugs with specific biological activities. For example, when developing new antimicrobial drugs or anticancer drugs, the compound can be used as a starting material and can be reacted in multiple steps to eventually obtain the target drug molecule.
It is also useful in the field of materials science. Due to its fluorine and bromine atoms, the material is endowed with unique properties. If it is introduced into polymer materials, the thermal stability, chemical stability and weather resistance of the material can be improved. When preparing high-performance coatings, plastics or fibers, the addition of this compound can optimize the performance of the material and make it more suitable for special environmental needs, such as aerospace, automotive industry and other fields that require strict material properties.
In addition, in pesticide chemistry, it can be used as an important raw material for the synthesis of new pesticides. With its structural characteristics, the synthetic pesticide may have the advantages of high efficiency, low toxicity and environmental friendliness, which can help to improve the yield and quality of crops while reducing the negative impact on the environment. Overall, 4-bromo-1,2-[ (difluoromethylene) dioxy] benzene plays an important role in many fields and is of great significance to promoting the development of related industries.

4-Bromo-1,2-[ (difluoromethylene) dioxy] benzene has various physical properties. The properties of this substance, whether it is a solid or a liquid at room temperature, depend on the specific conditions. Looking at its color, it is generally colorless to slightly yellow, and its appearance may appear crystal clear.
On its melting point, due to the interaction of bromine atoms, difluoromethylene dioxy and other groups in the molecular structure, the melting point value should be within a specific range. The introduction of bromine atoms increases the intermolecular force, which increases the melting point; and the existence of difluoromethylene dioxy has an impact on the way of molecular accumulation, which in turn fine-tunes the melting point. The boiling point is also affected by the structure. Many groups cooperate to make the energy required for the molecule to leave the liquid state different, resulting in a boiling point in the corresponding range.
The density of this substance depends on its molecular weight and the degree of close arrangement between molecules. The relative atomic weight of bromine atoms is larger, which gives the molecule a larger weight, and the regularity of the molecular structure also plays a role in the density. Overall, the density shows a specific value.
In terms of solubility, the solubility of this substance in organic solvents may be different. Because its structure contains aromatic rings, halogen atoms, fluoroxy groups, etc., it may have good solubility with some organic solvents such as aromatics and halogenated hydrocarbons due to similar miscibility principles. However, in water, due to its dominant hydrophobic groups, the solubility should be poor.
In addition, its volatility is also related to the intermolecular force. The intermolecular force is moderate, and the volatility may be at a certain level. Under appropriate temperatures and environments, it may evaporate slowly. And its optical properties such as refractive index also vary due to the distribution of electron clouds and group characteristics in the molecular structure, presenting unique physical constants, which are of great significance for identification and analysis in related fields.

The synthesis method of 4-bromo-1,2-dioxy-benzene follows a number of paths. First, catechol is used as the starting material, and ethyl difluorobromoacetate is catalyzed by a base. The base, such as potassium carbonate and sodium hydroxide, reacts in suitable solvents, such as N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), and the temperature is controlled at a certain range, or 40-80 degrees Celsius. After a few times, the intermediate product is obtained. This intermediate product is then hydrolyzed and decarboxylated. Hydrolysis is promoted by acid or base. Hydrochloric acid and sulfuric acid can be used for acids, and potassium hydroxide and sodium hydroxide are feasible for bases. The decarboxylation reaction may require heating at an appropriate temperature, such as 150-200 degrees Celsius, to obtain the target product 4-bromo-1,2-[ (difluoromethyl) dioxy] benzene.
Second, 4-bromocatechol is used as a raw material to react with dichloromethane under specific conditions. This reaction may require a catalyst, such as some metal salts, and is carried out under specific pressure and temperature environments. The target product can also be obtained in suitable organic solvents such as toluene and chlorobenzene at a pressure of 1-5 atmospheres and a temperature of 80-120 degrees Celsius.
Or an aryl halide containing difluoromethylene dioxy is prepared first, and then the halogen atom is substituted. For example, a suitable halogenated aromatic hydrocarbon is reacted in a solvent with a difluoromethylene dioxy reagent, catalyzed by a metal such as palladium, in the presence of a base. The base can be sodium carbonate, potassium tert-butanol, solvents such as 1,4-dioxane, tetrahydrofuran, and the reaction temperature can be 60-100 degrees Celsius, and the synthesis of 4-bromo-1,2-[ (difluoromethylene) dioxy] benzene can be achieved. All methods have advantages and disadvantages, and the practical application needs to be weighed according to factors such as the availability of raw materials, cost, and difficulty of reaction conditions.

I don't know the price range of 4 - Bromo - 1,2 - [ (Difluoromethylene) Dioxy] Benzene on the market. This is a relatively uncommon chemical substance, and its price often varies due to many factors. Such as the complexity of the production process, if the preparation requires exquisite and high-cost processes, the price will be high; furthermore, the market supply and demand situation, if there are many people who want it and there are few people who supply it, the price will also rise; in addition, the purity requirement is also the key, and the price of high purity is naturally higher than that of low purity.
To know the exact price range, when visiting a professional chemical reagent supplier, ask for its price list. You can also explore it on the chemical product trading platform, which often lists the prices of various chemical products for reference. Or consult with industry experts and chemical company personnel, who may know the approximate price range due to their rich experience. Unfortunately, it is difficult for me to determine the price geometry at the moment, and it needs to be studied carefully through the above channels.

4-Bromo-1,2 - [ (difluoromethylene) dioxy] benzene, this is a chemical substance. Its storage conditions are crucial to the stability and safety of this substance.
This substance should be stored in a cool, dry and well-ventilated place. A cool environment can avoid chemical reactions caused by high temperature. High temperature can often accelerate the movement of molecules, or cause changes such as chemical bond breaking and rearrangement, which can cause the substance to deteriorate. A dry environment is also indispensable, because moisture or water vapor can interact with the substance. Or cause hydrolysis reactions, which can damage its chemical structure and affect its quality and performance. Good ventilation can disperse harmful gases that may be generated in time, and avoid potential safety hazards caused by gas accumulation, such as explosion, poisoning, etc.
Furthermore, when storing, keep away from fire and heat sources. Both fire and heat sources are potential sources of ignition. This chemical substance may be flammable. In case of open flames and hot topics, it is easy to cause combustion or even explosion, endangering the safety of personnel and facilities. And it must be stored separately from oxidants and edible chemicals, and mixed storage should not be avoided. Because oxidants are highly oxidizing or react violently with the substance, edible chemicals are mixed with it, or cause accidental ingestion, causing serious consequences.
At the same time, the storage area should be equipped with suitable materials to contain leaks. In the unfortunate event of leakage, measures can be taken to collect it in time to prevent its spread, reduce pollution to the environment and harm to human health. In short, the above storage conditions can be followed to ensure the safe storage and quality stability of 4-bromo-1,2-[ (difluoromethylene) dioxy] benzene.