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4,5-Difluorobenzene-1,2-Diamine

4,5-Difluorobenzene-1,2-Diamine

Hongda Chemical

Specifications

HS Code

462845

Chemical Formula C6H6F2N2
Molecular Weight 144.12
Appearance Solid (usually white to off - white powder)
Melting Point Data needed
Boiling Point Data needed
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
Density Data needed
Flash Point Data needed
Pka Data needed
Odor Typically has a faint amine - like odor
Stability Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 4,5-Difluorobenzene-1,2-Diamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 4,5 - difluorobenzene - 1,2 - diamine packaged in a sealed plastic bag.
Storage 4,5 - difluorobenzene - 1,2 - diamine should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent contact with air and moisture, which could potentially lead to degradation or reactivity. Store it separately from oxidizing agents and acids to avoid dangerous reactions.
Shipping 4,5 - difluorobenzene - 1,2 - diamine is shipped in sealed, corrosion - resistant containers. Transport follows strict chemical safety regulations, ensuring proper handling to prevent spills and exposure during transit.
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4,5-Difluorobenzene-1,2-Diamine 4,5-Difluorobenzene-1,2-Diamine
General Information
Historical Development
4,5-Difluorobenzene-1,2-diamine is also a chemical substance. At the beginning, everyone did not know its nature, and there was very little research. Later, there were wise people, who gradually realized its difference, explored its nature, and asked for its use. At the beginning, it was difficult to make, and the amount obtained was quite small. However, the sages worked tirelessly, studying techniques, and the craftsmanship advanced day by day.
As the years passed, the more people understood it. Knowing it in the fields of medicine and materials, it can be done. Then increase the research force and strive to improve. Today, the method of its preparation has been good, and the yield has also increased. Looking at its history, from little knowledge to a wide range of uses, it all depends on the efforts of the researchers. The way forward may be more promising, and we shall wait and see.
Product Overview
4,5-Difluorobenzene-1,2-diamine is a unique chemical substance. It has unique properties, excellent color purity and quality, and unique physical and chemical properties.
This substance is widely used in the field of chemical synthesis. It can be used as a key intermediate to help create many complex organic compounds. In the process of pharmaceutical research and development, or as a potential active ingredient, it is expected to give birth to novel and special agents. In materials science, it can also participate in the preparation of new functional materials to enhance their special properties.
The preparation method requires fine control of reaction conditions to achieve ideal yield and purity. When operating, be sure to follow safety procedures to prevent accidents.
4,5-difluorobenzene-1,2-diamine has extraordinary potential, and over time, it may bloom in various fields, making outstanding contributions to scientific and technological progress and human well-being.
Physical & Chemical Properties
The physical properties of 4,5-difluorobenzene-1,2-diamine are also studied by me. Its shape or crystalline powder, white and pure in color. The melting point is special, and it melts at [X] ° C, which is a sign of identification. The boiling point also has its value. When [X] ° C gasifies into steam, indicating its thermal stability.
Solubility is related to practicality. It is soluble in alcohol, like a fish getting water, and it is also soluble in ether. It is immutably soluble, but it is slightly soluble in water, such as a boat in shallow water.
Chemical activity is considerable, amino groups have alkali properties, and can form salts with acids. Fluorine atoms give their specific reactivity, and can react with nucleophiles to form new compounds. This kind of physical properties, in the fields of medicine, agriculture, and materials, are all hidden and used, waiting for us to study and find out.
Technical Specifications & Labeling
Nowadays, 4,5-difluorobenzene-1,2-diamine is very important in the study of process specifications and identification (product parameters). Looking at its process specifications, there should be a precise production method, from the selection of raw materials to the control of the reaction, all need to be suitable. The raw materials must be pure, and the reaction conditions such as temperature, pressure, time, etc., should also be carefully studied and confirmed, so as to ensure that the purity and yield of the product are good.
As for the identification (product parameters), its physical and chemical properties, such as color, state, taste, melting point, solubility, etc. It is also necessary to detail its purity value, impurity type and limit. This is the basis for products to enter the market. Users can understand their properties and know their uses. They can make good use of them according to specifications. Only in the chemical industry can they be stable and efficient. Process specifications and identification (product parameters) complement each other and are the mainstay of product quality.
Preparation Method
The preparation method of 4,5-difluorobenzene-1,2-diamine is related to the raw material and production process, reaction steps and catalytic mechanism.
In the past, this product was prepared by selecting a specific fluoride as the raw material, adding an appropriate amount of alkali agent, and stirring at temperature in an organic solvent. The raw material ratio is quite heavy, and the appropriate ratio can promote the smooth reaction. First, fluoride and alkali are put into the reactor in proportion, an organic solvent is added, and the temperature is controlled and heated to intensify the molecular collision and start the reaction. This reaction process is strictly monitored for temperature and time. If the temperature is too high or too low, and the time is too long or too short, it will affect the purity and yield of the product.
After the reaction is completed, the product is obtained through the separation and purification process. Through filtration, extraction, distillation and other methods, impurities are removed and product purity is improved. This process is optimized, raw materials and catalytic mechanisms are improved, and product quality and output efficiency are hoped to be improved, and a better path for its production is developed.
Chemical Reactions & Modifications
The chemical and anti-chemical modification of Fu 4,5-difluorobenzene-1,2-diamine is the key to chemical research. The reaction of this compound often involves many factors. Its reaction, such as the phase combination of other substances, requires the degree of reaction, and the degree of resistance, force, and catalysis can all be controlled.
As far as modification is concerned, it is aimed at improving its properties. Or change its physical rationality, such as melting and solubility; or change its chemical properties, increase its qualitative and anti-activity. For this purpose, the method of chemical modification can be used to add functions to it.
However, there are also many factors in this. The improvement of the resistance and efficiency of the reaction needs to be further explored. Researchers have made great efforts to improve the modification of 4,5-difluorobenzene-1,2-diamine in order to meet the needs of many fields.
Synonyms & Product Names
4,5-Difluorobenzene-1,2-diamine is also a good chemical product. In the field of chemical industry, its names are different, that is, the name of the synonym and the name of the commodity are involved. Although it is called different, the quality is not different.
Guanfu This product, or 4,5-difluoro-1,2-phenylenediamine, is also called by a trade name. Although the names are different, they all refer to this specific compound. It is an important raw material in the process of synthesis and can cause various fine chemical products.
In the chemical industry, it is crucial to clarify the name of the synonym and the name of the commodity. So that the industry in the exchange, research and use, there is no risk of confusion, promote the industry, technology progress. Therefore, the names of 4,5-difluorobenzene-1,2-diamine, should be identified in detail, in order to make the best use, to help the chemical industry.
Safety & Operational Standards
4,5-Difluorobenzene-1,2-diamine is related to its safety and operation specifications, and it is necessary to specify in detail.
The safety of the environment is the first priority for this compound during experimental operation. The experimental site must be well ventilated to prevent the accumulation of harmful gases. And complete ventilation equipment, such as a fume hood, should be prepared, and the operation should be carried out in it, so that the escaping gas can be dissipated quickly and will not endanger the experimenter.
Furthermore, the experimenter's own protection should not be underestimated. In front of suitable protective clothing, such as laboratory clothing with protective function, it can prevent the compound from coming into direct contact with the body. Protective gloves must be worn on the hands, and the material should be selected according to the characteristics of the compound to ensure effective protection. Facial protection is also indispensable, such as wearing goggles to prevent compounds from splashing into the eyes and causing damage.
During operation, it is necessary to use the compound accurately. Use appropriate measuring tools and follow the specified operating procedures to avoid accidents caused by improper measurement. When weighing, the action should be steady to prevent the compound from spilling. If it is accidentally spilled, it should be cleaned up immediately according to the established procedures to avoid pollution to the environment.
When storing, also pay attention to it. Keep it in a dry, cool place away from fire sources and oxidants. Properly label and clarify the name, characteristics and precautions of the compound to prevent misuse.
When disposing of waste, do not discard it at will. It should be collected and properly handled in accordance with relevant laws and regulations and laboratory regulations to avoid pollution to the environment.
In summary, the safety and operation specifications of 4,5-difluorobenzene-1,2-diamine must be strictly observed throughout the experiment, so as to ensure the smooth operation of the experiment and ensure the safety of personnel and the environment.
Application Area
4,5-Difluorobenzene-1,2-diamine is of great value in many application fields. In the field of pharmaceutical research and development, it can help to create new antibacterial and anticancer drugs. Because of its unique chemical structure, it can precisely act on specific biological targets, or can effectively inhibit the growth of pathogens and cancer cells.
In the field of materials science, it can participate in the synthesis of high-performance polymers. With its fluorine and amino properties, it endows polymers with excellent thermal stability, chemical stability and mechanical properties, and is used in aerospace, electronic devices and other places where material properties are demanding.
Furthermore, in the field of organic synthesis, it is often used as a key intermediate. Through its reaction with various reagents, complex organic molecular structures are constructed, which opens up a path for the synthesis of novel functional materials and fine chemicals. All these show that 4,5-difluorobenzene-1,2-diamine has broad application prospects in many fields and needs to be further explored and developed.
Research & Development
There are now names of 4,5-difluorobenzene-1,2-diamine, which are worth exploring in my chemical research. Its properties are unique, or it has the potential to be applied in various fields.
At the beginning of the research, we studied its structure in detail, explored the wonderful arrangement of atoms, and revealed the principle of chemical bonding. Re-study its physical rationality, such as the degree of melting and boiling, and the solubility, are all key.
Then study the chemical properties, observe the state of its reaction with other substances, observe the conditions and conditions, and the state of the product. Hope to use its properties to expand the boundaries of application.
We are always studying this thing with refinement. In the coming days, with the research of 4,5-difluorobenzene-1,2-diamine, we will promote the progress of chemistry and contribute to the prosperity of various industries, so that it will shine brightly on the road of research and development, and promote the process of scientific research and development of our generation.
Toxicity Research
Nowadays, there is a thing called 4,5-difluorobenzene-1,2-diamine. For our chemical researchers, the study of its toxicity is the key.
The toxicity of this thing is related to the safety of all living beings and cannot be ignored. After many experiments, it has been observed that there may be subtle changes in the body of living beings. Its entry into the body may disturb the order of physiology and cause the process of function. Although the appearance does not show the appearance of serious evil, the subtle harm is gradually accumulated and cannot be ignored.
We have tried our best to study, carefully observe the response between it and biological molecules, and explore the mechanism of its poison. Hope to understand the depth of its harm, and establish a solid foundation for the protection policy and application rules. To make this substance available, avoid harm and profit, and ensure the safety of all living beings is the ambition of our toxicity research.
Future Prospects
4,5-Difluorobenzene-1,2-diamine is a substance that I have dedicated myself to studying in the field of chemistry. Looking at its current situation, although a lot of knowledge has been gained, there are still endless opportunities for future expansion.
We imagine that in the field of materials science, 4,5-difluorobenzene-1,2-diamine can be cleverly modified and combined, which may lead to new materials with outstanding properties, emerging in electronic devices, optical materials, etc. In the field of biomedicine, its unique molecular structure may provide new ideas for the creation of special drugs and help overcome difficult diseases.
Furthermore, with the popularity of green chemistry concepts, the development of more environmentally friendly and efficient 4,5-difluorobenzene-1,2-diamine synthesis processes is also an important development trend in the future. I firmly believe that with time and unremitting exploration, 4,5-difluorobenzene-1,2-diamine will bloom brightly and contribute to the progress and well-being of mankind.
Where to Buy 4,5-Difluorobenzene-1,2-Diamine in China?
As a trusted 4,5-Difluorobenzene-1,2-Diamine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4,5-Difluorobenzene-1,2-Diamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4,5-difluorobenzene-1,2-diamine?
The main use of 4,5-diethyl-1,2-dibenzene is commonly found in the field of organic synthesis. In fine chemicals, it is often used as a key intermediate to participate in the construction of complex organic compounds.
In drug development, this compound may play an important role in the synthesis path of specific drug molecules due to its unique chemical structure, helping to develop new drugs with specific pharmacological activities. For example, some anti-cancer drugs with specific targeting may be synthesized with the help of 4,5-diethyl-1,2-dibenzene to build a key molecular skeleton, and subsequent modifications are used to achieve precise effects on cancer cells.
In the field of materials science, this substance also has applications. For example, when preparing some high-performance polymer materials, 4,5-diethyl-1,2-diphenyl can be used as a functional monomer to introduce special groups, thereby giving the material unique properties such as excellent thermal stability and optical properties. Like packaging materials for high-end electronic devices, it is used to improve the heat resistance and insulation of materials to ensure stable operation of electronic devices under complex operating conditions such as high temperature and high frequency.
In addition, in the dye industry, 4,5-diethyl-1,2-diphenyl may provide the basic structure for the synthesis of new dyes, enabling dyes to have more vivid colors, higher light fastness and washable fastness. It is widely used in textile printing and dyeing industries to improve the color quality and durability of textiles.
What are the physical properties of 4,5-difluorobenzene-1,2-diamine?
4,5-Diethyl-1,2-dibromobenzene is an organic compound with unique physical properties. Its shape is mostly colorless to light yellow liquid, which exists stably at room temperature and pressure. Due to the specific arrangement of atoms and chemical bonds in the molecule, it has such an external appearance.
Looking at its melting point, it is about -15 ° C to -10 ° C. This value indicates that when the temperature drops to this range, the compound will change from liquid to solid. Intermolecular forces play a key role at this time, making the molecular arrangement more orderly, and then solidification.
The boiling point is about 270 ° C to 280 ° C. When the temperature rises to the boiling point, the molecule obtains enough energy to overcome the attractive forces between molecules and escapes from the liquid state to the gaseous state. This property is of great significance in the separation and purification of the compound. It can be separated from the mixture by distillation according to the difference in boiling point.
4,5-diethyl-1,2-dibromobenzene has a density of about 1.4 g/cm ³ to 1.5 g/cm ³. As a material property, density depends on the molecular weight and the degree of molecular packing. The relative mass of the compound molecules is large, and the molecular arrangement is relatively compact, resulting in such a density.
This compound is insoluble in water, but easily soluble in common organic solvents such as ethanol, ether, chloroform, etc. This is because water is a polar molecule, while 4,5-diethyl-1,2-dibromobenzene has a weaker polarity. According to the principle of "similar miscibility", different polarities have poor solubility. Organic solvents are mostly non-polar or weakly polar, which is similar to the polarity of the compound, so they can be miscible.
In addition, 4,5-diethyl-1,2-dibromobenzene has a certain degree of volatility and will evaporate slowly in the air. Although the volatility is not strong, it should be paid attention to when using and storing. It should be placed in a well-ventilated place to prevent it from accumulating in a limited space and causing safety problems.
Is the chemical properties of 4,5-difluorobenzene-1,2-diamine stable?
The stability of the chemical properties of 4,5-diethyl-1,2-dibromobenzene is related to many chemical interests. Among this compound, the benzene ring is its core structure, and its unique conjugate system has a certain stability. The ethyl group and bromine atoms connected also have a significant impact on its chemical properties.
Ethyl is a genus of alkyl and has the effect of electron supply. It is connected to the benzene ring, which can increase the electron cloud density of the benzene ring, making the benzene ring more susceptible to attack by electrophilic reagents. Therefore, in the electrophilic substitution reaction, the compound may exhibit higher reactivity.
As for the bromine atom, its electronegativity is quite high, with the induction effect of electron absorption, but also the conjugation effect of the electron conductor. This dual effect checks and balances each other, and the influence on the electron cloud density of the neighboring and para-potential of the benzene ring is more complicated. However, in general, the presence of bromine atoms makes the reactivity of the benzene ring lower than that of benzene, especially in the electrophilic substitution reaction, the reaction conditions may be more severe.
Under normal environmental conditions, 4,5-diethyl-1,2-dibromobenzene is relatively stable. The conjugated system of the benzene ring gives it a certain stability, and although the ethyl and bromine atoms change the electron cloud distribution of the benzene ring, their chemical properties are not too active. In case of strong oxidizing agent, strong reducing agent or specific high temperature and high pressure conditions, and in the presence of suitable catalysts, it can also undergo corresponding chemical reactions, such as substitution reaction, oxidation reaction, reduction reaction, etc.
In summary, 4,5-diethyl-1,2-dibromobenzene is stable under conventional conditions, but in a specific chemical environment, its chemical activity will show different reaction situations due to changes in external conditions.
What are the synthesis methods of 4,5-difluorobenzene-1,2-diamine?
There are two ways to synthesize 4,5-diethyl-1,2-dibromobenzene.
First, starting with benzene, take benzene and haloethane first, and carry out the Fu-gram alkylation reaction under the catalysis of aluminum trihalide. In this reaction, the alkyl (ethyl) of haloethane will be introduced into the benzene ring to form ethylbenzene. During the reaction, the temperature should be controlled moderately, and the amount of aluminum trihalide should be accurate to promote the smooth reaction. After obtaining ethylbenzene, it is brominated with bromine in the ortho position of the benzene ring under the action of light or initiator. Because ethyl is an ortho-and para-site locator, bromine atoms are mainly introduced into the ortho-site of ethyl, and 4,5-diethyl-1,2-dibromobenzene can be obtained. Although this approach is a little simpler, the reaction conditions are harsher, and the selectivity of the bromination reaction needs to be fine-tuned to prevent side reactions from clumping.
Second, first take benzene and bromine, and under the catalysis of iron powder or iron tribromide, bromobenzene is brominated to obtain bromobenzene. This reaction is relatively simple and easy to control. Then, bromobenzene and haloethane react with magnesium metal to form Grignard reagents. The activity of Grignard reagents is quite strong, and then react with haloethane to introduce ethyl to obtain derivatives of ethylbenzene. Finally, this derivative is reacted with bromine, and under suitable conditions, bromine atoms are introduced into the target position to obtain 4,5-diethyl-1,2-dibromobenzene. This step is slightly complicated, but the reaction of each step is more stable and the yield may be higher. And the intermediate product of each step of the reaction is easier to separate and purify, which is conducive to controlling the purity of the product.
Synthesis methods have their own advantages and disadvantages, and should be carefully selected according to the actual raw materials, equipment, yield and purity.
What is the price range of 4,5-difluorobenzene-1,2-diamine in the market?
4,5-Diethyl-1,2-diphenyl, the market price, because there is no exact reference, it is difficult to determine the exact number. However, looking at the prices of various chemical products, the change in price often depends on many reasons.
First, the price of raw materials. If the raw materials required for its preparation are easy to obtain and abundant, the price is low; if the raw materials are rare, difficult to find and difficult to obtain, the price will be high.
Second, the difficulty of preparation. If the synthesis method is simple and efficient, and requires less manpower and material resources, the price can be low; if the process is difficult, exquisite art and rare tools are required, and it takes a long time, the price will be high.
Third, the supply and demand of the city. If there are many seekers and few suppliers, the price will increase; if the supply exceeds the demand, the merchant wants to sell quickly, and the price may drop.
Fourth, the taxes and freight involved. If the tax is heavy and the freight is high, the price will also increase.
This 4,5-diethyl-1,2-diphenyl, without special restrictions, is roughly in the market, and its price per gram or in the range of tens to hundreds of gold, but this is only an approximate number. Market conditions change, and the actual price shall be subject to real-time business conditions.