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4,5-Dichloro-2-Fluoronitrobenzene

4,5-Dichloro-2-Fluoronitrobenzene

Hongda Chemical

Specifications

HS Code

573372

Chemical Formula C6H2Cl2FNO2
Molar Mass 208.0 g/mol
Appearance Yellow to light brown solid
Melting Point 39 - 42 °C
Boiling Point 238 - 240 °C
Density 1.59 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low
Flash Point 101 °C
Hazard Class Irritant, harmful if swallowed

As an accredited 4,5-Dichloro-2-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4,5 - dichloro - 2 - fluoronitrobenzene in a sealed chemical - resistant container.
Storage 4,5 - dichloro - 2 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and direct sunlight. It should be kept in a tightly - sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and bases to avoid potential chemical reactions. Comply with local regulations for storing hazardous chemicals.
Shipping 4,5 - dichloro - 2 - fluoronitrobenzene, a chemical, is shipped in sealed, corrosion - resistant containers. Strict compliance with hazardous material shipping regulations ensures safe transportation to prevent leakage and environmental risks.
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4,5-Dichloro-2-Fluoronitrobenzene 4,5-Dichloro-2-Fluoronitrobenzene
General Information
Historical Development
4,5-Dichloro-2-fluoronitrobenzene is also a chemical substance. The beginning of its production is due to the research and development of many scholars, and it has improved over the years. In the past, all the workers worked hard in the room, and they tried their best to explore the way of its preparation by chemical methods. At the beginning, the results were not obvious, but many people worked tirelessly. Try it again and again, and you can get a good method.
Over the years, the technique is gradually refined. The method of preparation is improving day by day, and the yield is also increasing. Its use in industry is gradually emerging, and it is required for all kinds of products. From this perspective, the development of 4,5-dichloro-2-fluoronitrobenzene is due to the perseverance of predecessors, which has achieved today's success and occupied a place in the field of chemistry.
Product Overview
4,5-Dichloro-2-fluoronitrobenzene is an important substance in chemical research. Its form is solid, color or light yellow. This substance is unique and has a wide range of uses in the field of organic synthesis.
Its preparation method is through a specific reaction path. It needs to be strictly controlled at temperature, select the appropriate raw materials, and follow a precise ratio. The reaction mechanism is exquisite, involving halogenation, nitrification and other reactions, each step is related to the purity and yield of the product.
In terms of application, it is often a key intermediate and can be derived from a variety of high-value compounds. For example, in the pharmaceutical field, it helps to synthesize special drugs; in materials science, or as the cornerstone of the creation of novel functional materials.
However, when preparing and using, attention must be paid to safety. Because of its certain toxicity and corrosiveness, the operation should be done in a well-ventilated and well-protected environment, in accordance with standard laws, to prevent harm to people and the environment.
Physical & Chemical Properties
4,5-Dichloro-2-fluoronitrobenzene, an organic compound. Its color may be light yellow, it is crystalline, and has a specific melting boiling point. The melting point is about [X] ° C, and the boiling point is around [X] ° C. The density of this substance is related to its application. And its solubility is also particular. It is slightly soluble in organic solvents such as ethanol and ether, but it is insoluble in water.
Its chemical properties are active, and the halogen atom and nitro group on the benzene ring can initiate a series of reactions. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and makes it easier to nucleophilic substitution. Halogen atoms can participate in nucleophilic substitution, coupling and other reactions, and are widely used in the field of organic synthesis. They can be used as intermediates in the synthesis of medicines, pesticides, etc., and assist in the preparation of many organic compounds.
Technical Specifications & Labeling
For 4,5-dichloro-2-fluoronitrobenzene, it is also a chemical substance. To clarify its technical specifications and identification (product parameters), follow a certain method. When its color is pure, there is no disturbance of variegated colors, and it is solid, the shape and quality are uniform. Looking at its taste, it should have the inherent taste of this product, and there is no peculiar smell. On its purity, it must meet a specific standard, and the amount of impurities must not exceed the limit. On the label, the name of the product, the chemical formula, and the parameters of the content must be clearly identifiable, and there is no suspicion of error. In this way, meeting the requirements of technical specifications and labels can be used in various chemical industries, contributing to the prosperity of the industry, and living up to the painstaking efforts of developers. In order to comply with the prevailing regulations of the industry, it can be easily circulated in the city for all parties.
Preparation Method
The method of preparing 4,5-dichloro-2-fluoronitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism.
To make this product, specific raw materials can be used. First take an appropriate amount of the initial reactants containing chlorine, fluorine and nitro groups, and mix them according to the precise ratio. The production process needs to be carried out under a specific temperature and pressure environment. At the beginning of the reaction, in a closed reactor, heat the mixture at a moderate temperature to activate the molecules and promote the reaction.
The reaction steps are gradual. In the first step, the raw materials initiate a substitution reaction, and the chlorine atoms and fluorine atoms occupy the corresponding positions in the benzene ring according to specific rules. In the next step, the nitro group is ingeniously connected to achieve the required molecular structure. In this process, the catalytic mechanism is crucial. Using high-efficiency catalyst can greatly improve the reaction rate and product purity. The catalyst reduces the activation energy of the reaction and promotes the molecule to collide and combine more easily. After such operations, 4,5-dichloro-2-fluoronitrobenzene products can be obtained.
Chemical Reactions & Modifications
The chemical reaction and modification of 4,5-dichloro-2-fluoronitrobenzene are related to many wonders.
In the past, the way of reaction of this compound was investigated, or according to the conventional method, sometimes it did not reach the state of refinement. If the reaction conditions are slightly poor, the quality and quantity of the product will be affected.
Now I want to change the method to improve the environment. Observe its structure, think about what kind of reagent and what kind of conditions can promote the reaction smoothly, and the product is pure. Or adjust the temperature, or change the type of solvent, hoping to be able to react in the reaction, and get better results. Taking into account the effectiveness of the catalyst, if the catalyst can be selected, the reaction may be accelerated and its efficiency increased, and the characteristics of the product may be changed accordingly to meet different needs. In this way, unremitting research will surely be able to obtain more new gains in the chemical reaction and modification of 4,5-dichloro-2-fluoronitrobenzene, opening up new avenues for its practical application.
Synonyms & Product Names
4,5-Dichloro-2-fluoronitrobenzene is also a chemical substance. Its synonymous name and the name of the commodity are quite important in the industry.
In the field of Guanfu chemistry, the same substance may be called by different methods, uses, and origins. 4,5-Dichloro-2-fluoronitrobenzene is no exception. Its synonymous name is ordered by chemists according to its structure and properties. It is precise and professional, and is the basis for academic communication. The name of the commodity is more concerned with the needs of marketing and marketing, and strives to be concise and easy to remember for promotion.
Although the two refer to the same thing, they have their own uses in different situations. Scholars discuss and document describe, and take more synonymous names to show rigor; merchants trade and product promotion, and use the names of commodities to attract attention. In the process of chemical research and industrial development, clarify the synonymous names and trade names of 4,5-dichloro-2-fluoronitrobenzene, so as to promote the prosperity of chemistry.
Safety & Operational Standards
Specifications for safety and operation of 4,5-dichloro-2-fluoronitrobenzene
For 4,5-dichloro-2-fluoronitrobenzene, chemical products are also different in nature, which are related to safety and operation standards and cannot be ignored.
As far as safety is concerned, this product is toxic or causes human damage. In contact with it, protective equipment must be worn, such as protective clothing, gloves, and goggles, to prevent it from contacting the eyes. And its gas may be harmful, it is suitable to operate it in a well-ventilated place, and prepare ventilation devices to avoid the accumulation of toxic gases. When storing, it must be in a cool, dry and ventilated place, avoiding fire and heat sources, and away from incompatible things to prevent accidents.
As for the operating specifications, know the nature and risks before use, and follow the procedures. The measurement is accurate, the equipment is clean, and impurities are prevented from mixing and causing abnormal reactions. The reaction conditions are strictly controlled, and the temperature, pressure and time must be appropriate, and no deviations should be made. Diet and smoking are prohibited in the operation room. After completion, clean your hands and face, except for protective equipment. Waste is disposed of in accordance with regulations, and cannot be discarded at will, so as not to pollute the environment.
Anyone who handles this object should be in awe and strictly abide by safety and operating standards. In this way, personal safety, the environment is clean, and the experimental production is smooth.
Application Area
4,5-Dichloro-2-fluoronitrobenzene is also a chemical product. Its application field is quite extensive. In the field of medicinal chemistry, it can be a key intermediary for synthesizing various specific drugs and curing various diseases. In the field of pesticide creation, it also plays an important role in assisting in the research of efficient and low-toxic pesticides to protect the abundance of agricultural production. In the field of material science, or participating in the preparation of special materials, giving materials specific properties.
Looking at its application, in pharmaceutical research and development, it can use its unique chemical structure to build a new molecular structure of drugs and expand treatment methods. In the development of pesticides, it can accurately target the characteristics of pests and improve the effectiveness of pesticides. In the synthesis of materials, it can add its characteristics and open up new frontiers for materials science. This highlights the extraordinary value of 4,5-dichloro-2-fluoronitrobenzene in the application field and promotes the progress and development of related industries.
Research & Development
There is a chemical substance today, named 4,5-dichloro-2-fluoronitrobenzene. Our generation is a chemical researcher, and it is quite laborious to explore it.
At the beginning, I wanted to obtain the pure product of this compound, and went through various attempts. From the selection of raw materials to the fine adjustment of reaction conditions, it is all done with caution. The temperature of the reaction, the length of time, and the ratio of reagents are all related to the quality of the product.
During this period, there are many difficulties. For example, the reaction rate is slow, or there are too many impurities in the product. However, we have not given up, we have thought about it repeatedly, consulted ancient books and classics, learned from the methods of predecessors, and combined with today's new techniques.
Finally, it has achieved success, not only can it obtain high-purity 4,5-dichloro-2-fluoronitrobenzene stably, but also progress in mass production. In the future, we hope to use this as a basis to further explore its application in medicine, materials and other fields, promote its development, and contribute to the progress of chemistry.
Toxicity Research
4,5-Dichloro-2-fluoronitrobenzene is also an important substance in chemical research. We must be cautious about toxicity studies. Looking at its structure, chlorine, fluorine and nitro coexist, and these groups may cause them to have special toxicity.
After various experiments, it can be known that this substance may be potentially harmful to organisms. Its entry into the body may disturb the normal order of physiology and damage the function of organs. At the cell level, it may also affect the processes of metabolism and division.
Although it has a wide range of uses in the chemical industry, the risk of toxicity should not be ignored. It is necessary to conduct in-depth research to clarify its mechanism of action, toxicity intensity and transmission route, so as to determine proper protection policies and rules for rational use, so as to avoid the harm of life and protect the environment and personal safety.
Future Prospects
Today there is a thing called 4,5-dichloro-2-fluoronitrobenzene. We study it, and we have great ambitions for its future development. This material is very different and has a wide range of uses.
Looking at today's world, science and technology are changing day by day, and industry is booming. 4,5-dichloro-2-fluoronitrobenzene can be used in various fields, either as a raw material or as an adjuvant. In the field of medicine, or in the creation of new drugs, to treat human diseases; in the study of materials, or into novel things, in response to the needs of the times.
Our generation should study it diligently, explore its subtlety, and expand its use. Over time, make this substance shine and be a blessing to future generations. Make the future world more prosperous because of the good use of 4,5-dichloro-2-fluoronitrobenzene.
Where to Buy 4,5-Dichloro-2-Fluoronitrobenzene in China?
As a trusted 4,5-Dichloro-2-Fluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4,5-Dichloro-2-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4,5-dichloro-2-fluoronitrobenzene?
4,5-Difluoro-2-methoxybenzaldehyde is a crucial intermediate in the field of organic synthesis, and is widely used in the pharmaceutical, pesticide and materials industries.
In the field of medicine, it is a key starting material for the synthesis of a variety of drugs. For example, a specific chemical structure can be constructed through a series of chemical reactions to develop compounds with specific biological activities, which can play a therapeutic role in various diseases such as cardiovascular diseases and neurological diseases. With its unique chemical structure, it can precisely regulate the interaction between drugs and biological targets, and improve drug efficacy and selectivity.
In terms of pesticides, pesticides synthesized on this basis have efficient killing or repelling effects on pests, and are relatively friendly to the environment. Due to its active chemical properties, it can participate in the synthesis of novel pesticide molecules, enhance the specificity of pesticides to specific pests or diseases, reduce the impact on beneficial organisms, and meet the needs of modern green agriculture development.
In the field of materials, 4,5-difluoro-2-methoxybenzaldehyde can be used as an important building block for the synthesis of functional materials. By reacting with other compounds, materials with special optical and electrical properties can be prepared, such as functional materials for organic Light Emitting Diode (OLED), solar cells and other devices, contributing to the development of materials science. Due to the presence of fluorine atoms and methoxy groups in the structure, the material has unique physical and chemical properties, which can optimize material properties and expand the application range of materials.
What are the physical properties of 4,5-dichloro-2-fluoronitrobenzene?
4,5-Difluoro-2-methoxybenzophenone is a genus of organic compounds. Its physical properties are unique, let me tell them one by one.
Under normal conditions, this compound is mostly in a solid state. Looking at its color, it is often white or almost white powder. This feature is easy to identify with the naked eye. In many chemical experiments and industrial production, it can be regarded as the basis for preliminary judgment of its purity and state.
The melting point is about a specific range. The melting point is the critical temperature at which the substance changes from solid to liquid, and the melting point of 4,5-difluoro-2-methoxybenzophenone, so that when the corresponding temperature is controlled, the physical state change can be accurately grasped, which is of great significance for chemical operations such as separation and purification.
Speaking of solubility, it has a certain solubility in common organic solvents such as ethanol, ether, etc. This characteristic determines that in the chemical reaction, a suitable solvent can be selected to promote the reaction, so that the reactants can be fully contacted, and the reaction rate and yield can be improved. And because of its solubility characteristics, in the subsequent product treatment and separation process, it can also be selected according to this method.
The density is also a specific value. The physical quantity of density is related to the compactness of a substance. When storing, transporting, and participating in specific chemical processes, the characteristics of density affect the selection of containers, the measurement of materials, and other practical operations.
The physical properties of 4,5-difluoro-2-methoxybenzophenone, from appearance, melting point, solubility to density, play a key role in its research, production, and application in the field of chemistry, providing an important reference for relevant workers, enabling them to use this substance more scientifically and accurately.
What is the production method of 4,5-dichloro-2-fluoronitrobenzene?
The preparation of 4,5-difluoro-2-cyanobenzyl is a delicate chemical process. The method usually follows the following steps:
First, take suitable starting materials, such as aromatic compounds with specific substituents. In this case, aromatic hydrocarbons containing appropriate halogens and cyanyl precursors can be selected. After halogenation, fluorine atoms are precisely introduced at specific positions. This step requires careful selection of halogenating reagents and reaction conditions. When the halogenating reagents used have high selectivity and reactivity, such as specific fluorinated halogenating agents, the reaction conditions depend on the choice of temperature, solvent and catalyst. The appropriate temperature and solvent can promote the reaction in the desired direction, and the catalyst can effectively improve the reaction rate and yield.
Next, cyanylation reaction is carried out. The cyanyl group is substituted with the appropriate functional group to construct the cyanyl structure of the target molecule. This process requires the selection of suitable cyanide reagents, such as inorganic cyanides such as potassium cyanide and sodium cyanide, or organic cyanide reagents with specific activities. During the reaction, the reaction environment needs to be strictly controlled to ensure that the cyanylation reaction is efficient and there are few side reactions.
Furthermore, a series of post-processing steps such as extraction, washing, drying, distillation or column chromatography are used to separate and purify the product of 4,5-difluoro-2-cyanobenzyl with high purity. Extraction can separate the organic phase and the aqueous phase to remove impurities; washing further washes the residual reagents and by-products in the product; drying to remove the moisture contained in the product; distillation or column chromatography can achieve high purification of the product according to the physical and chemical properties of the product and impurities.
The whole production method requires fine control of each step of the reaction, and a deep understanding of chemical principles and operation skills to obtain high-quality 4,5-difluoro-2-cyanobenzyl products.
What are the precautions for storing and transporting 4,5-dichloro-2-fluoronitrobenzene?
4,5-Difluoro-2-fluorobenzylpyridine is a particularly critical chemical substance in the field of fine chemicals. During storage and transportation, special attention should be paid to the following:
First, the storage environment should be used with caution. This substance should be stored in a cool, dry and well-ventilated place, and must not be exposed to high temperature or humidity. High temperature can easily cause chemical reactions to occur and cause it to deteriorate; while humid environment may cause adverse reactions such as hydrolysis, which will damage its quality. I still remember that in the past, a workshop placed such chemicals in a humid warehouse, and it was not long before the quality deteriorated. The lesson was a painful one. Furthermore, be sure to store it separately from oxidants, acids, alkalis, etc., because contact with it is very likely to trigger violent chemical reactions, and even cause serious accidents such as combustion and explosion.
Second, the transportation process should not be sloppy at all. Be sure to ensure that the packaging is complete and tightly sealed before transportation. If the packaging is damaged, it is very likely to cause material leakage, which will not only cause pollution to the environment, but also threaten the safety of transporters. When choosing a transportation tool, it is necessary to consider whether it has corresponding protective measures and emergency equipment. If it encounters a leak during transportation, it should be able to respond effectively immediately. During transportation, avoid vibration, impact and friction, and cause danger due to excessive vibration or damage to material stability.
Third, whether it is storage or transportation, relevant personnel must undergo professional training and be familiar with the characteristics, hazards and emergency treatment methods of the substance. In the event of an emergency such as a leak or fire, they should be able to act quickly and accurately according to the plan to minimize losses and hazards. Such as wearing appropriate protective equipment and following established procedures to clean up leaks.
Storage and transportation of 4,5-difluoro-2-fluorobenzylpyridine requires comprehensive consideration from various aspects such as the environment, packaging, and personnel. There must be no slack, so as to ensure the safety of the process.
What is the market price range for 4,5-dichloro-2-fluoronitrobenzene?
4,5-Difluoro-2-methoxyphenylboronic acid, this substance is in the market, and its price range is wide, making it difficult to determine the exact value. The price of the cover varies due to many reasons, including the price of raw materials, the simplicity of the production method, the supply and demand of the market, and the quality.
On the price of raw materials, if the price of raw materials required for preparation is high, or due to rarity, low production, or difficulty in production, the cost will increase, and the price will also be high. If the production of raw materials is affected by weather, geography, and politics, the supply will change, and the price will fluctuate.
The simplicity of the production method is also important. If the system requires a multi-step reaction, or a special instrument, test, or a strict reaction, such as temperature, pressure, lazy atmosphere, etc., the cost will be high and the price will also rise. And the efficient and simple production method can reduce costs and control the price.
The supply and demand of the city is the key. If there are many people, there are few suppliers, and the supply does not offset the demand, and the price will rise. On the contrary, if the market supply exceeds the demand, the merchant will sell its goods, or reduce the price to promote.
The quality of the quality also affects the price. High quality, pure high, less miscellaneous, in scientific research, pharmaceutical and other demanding fields, more favored, the price can also be viewed. And those with inferior quality, the price must be low.
Generally speaking, the price per gram may range from tens to hundreds of yuan. For small quantities, such as scientific research, new sample preparation, and more high quality, the price may be high. And industrial mass production, strict cost control, or moderate quality, the price is also appropriate. For real-time price confirmation, you can consult a chemical dealer, a reagent company, or refer to the price of an online chemical trading platform to get a price close to the market.