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4-(5-(4-Fluorophenyl)-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Benzenesulfonamide

4-(5-(4-Fluorophenyl)-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Benzenesulfonamide

Hongda Chemical

    Specifications

    HS Code

    802072

    Chemical Formula C16H10F4N4O2S
    Molecular Weight 400.33
    Appearance Solid (usually)
    Physical State At Room Temp Solid
    Solubility In Water Low solubility
    Solubility In Organic Solvents May be soluble in some organic solvents like DMSO
    Melting Point Data may vary depending on purity
    Pka Relevant acidic/basic groups' pKa values can influence its behavior in solution
    Stability Stable under normal conditions if stored properly

    As an accredited 4-(5-(4-Fluorophenyl)-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram pack of 4-(5-(4 - fluorophenyl)-3-(trifluoromethyl)-1H - pyrazol - 1 - yl)benzenesulfonamide.
    Storage Store 4-(5-(4 - fluorophenyl)-3-(trifluoromethyl)-1H - pyrazol - 1 - yl)benzenesulfonamide in a cool, dry place away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and exposure to air, which could potentially lead to chemical degradation. Store separately from incompatible substances.
    Shipping 4-(5-(4 - fluorophenyl)-3-(trifluoromethyl)-1H - pyrazol - 1 - yl)benzenesulfonamide is shipped in sealed, corrosion - resistant containers. Special handling per chemical safety regulations ensures secure transport to prevent any leakage or damage.
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    4-(5-(4-Fluorophenyl)-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Benzenesulfonamide 4-(5-(4-Fluorophenyl)-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Benzenesulfonamide
    General Information
    Historical Development
    4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide has a long history of development. In the past, scholars devoted themselves to research and made unremitting progress on the road of chemical exploration. At first, only a brief glimpse of its properties, and the research progress was slow. However, with the passage of time, the technology has become more exquisite and the analytical methods have become more exquisite. Scholars gradually clarified its structural characteristics and gained insight into its reaction laws. After repeated experiments and unremitting improvement, the synthesis method has gradually matured and the yield has been improved. Today, this compound has emerged in many fields and has broad application prospects. Looking back at the past development path, it can be described as arduous and brilliant, and it has gathered the efforts and wisdom of countless researchers to lay a solid foundation for subsequent research and application.
    Product Overview
    Today there is a substance called 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide. This substance is also the result of our painstaking research. Its shape, either powder or crystal, varies depending on the environment.
    Looking at its structure, 4-fluorophenyl, trifluoromethyl and pyrazolyl are cleverly connected, and combined with benzenesulfonamide base, resulting in a unique structure. This structure endows it with specific physical and chemical properties. It may have certain solubility in organic solvents and can exhibit unique reactivity under specific reaction conditions.
    This material may have potential application value in the fields of medicine, materials, etc. However, in order to clarify its details, we still need to explore in depth, perfect its mechanism, observe its effectiveness, and hope to contribute to the development of related fields.
    Physical & Chemical Properties
    The physical and chemical properties of 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide are crucial. Looking at its morphology, or in the shape of a white crystalline powder, this is the characterization of its appearance. In terms of its solubility, it exhibits certain solubility in organic solvents such as methanol, ethanol, etc., while it dissolves slightly less in water, which is related to its dispersion in different media. Its melting point is in a specific range, about [X] ° C. This is an inherent physical constant of the substance, which is of great significance for its identification and purity judgment. In terms of chemical properties, because its structure contains pyrazolyl, fluorophenyl, trifluoromethyl, and benzenesulfonamide groups, it has unique reactivity and can participate in a variety of organic chemical reactions. It may have potential applications in the field of drug synthesis and materials science, and it is worth exploring in depth.
    Technical Specifications & Labeling
    There is now a product called 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide. To clarify its technical specifications and identification (product parameters), it is necessary to investigate its quality in detail.
    The quality of this product is related to technical specifications. The combination of fluorophenyl, trifluoromethyl and pyrazolyl is fixed. The fluorine position of fluorophenyl, the structure of trifluoromethyl, and the ring of pyrazolyl all need to be in accordance with the law. The chain of benzenesulfonamide should also meet the standard and should not be poor.
    As for the logo, it is necessary to show its name, mark its nature, and show its danger. For those who are famous, 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide is also. Those who are sexual, related to their chemical properties and physical properties, must be clearly identified in the logo. Those who are dangerous, if there is any harm, should also show it to warn everyone. In this way, the technical specifications and labels of this thing can be used by researchers.
    Preparation Method
    In order to prepare 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide, the method of preparation is related to the raw materials and production process, reaction steps and catalytic mechanism, which must be carefully investigated.
    First take an appropriate amount of 4-fluorobenzaldehyde and trifluorobenzaldehyde acetoacetate ethyl ester as the starting material, add an appropriate amount of basic catalyst in a suitable reaction vessel, control the temperature and duration, and promote the condensation reaction to obtain the key intermediate. This step requires careful observation of the reaction process and timely adjustment.
    Then, the intermediate reacts with hydrazine hydrate to form 5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole. This reaction also needs to control its conditions to ensure that the reaction is complete.
    The end reacts with benzenesulfonyl chloride to obtain the target product. The ratio of raw materials, the temperature, duration of the reaction and the catalyst are all related to the quality and quantity of the product. It needs to be carefully controlled to obtain high-quality 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide.
    Chemical Reactions & Modifications
    The chemical reaction and modification of 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide compounds are the focus of our chemical researchers. Looking at the reaction, it may involve nucleophilic substitution, or it is related to the change of electron clouds. The introduction of fluorophenyl and trifluoromethyl groups makes the electronic properties of molecules easier and affects the reactivity.
    The control of reaction conditions is crucial. Temperature, solvent, and catalyst all affect the reaction path and yield. If a suitable solvent is selected, the solubility of the reactants can be increased and the reaction speed can be promoted. The catalyst can reduce the reaction energy barrier and lead the reaction to the desired product.
    As for modification, the functional group can be increased in the benzene ring or pyrazole ring to adjust its physicochemical and biological activity. Or introduce polar groups to change its solubility; or add conjugated structures to change its optical properties. All these are the way for chemical researchers to create more effective compounds through reaction and modification.
    Synonyms & Product Names
    4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide, its synonymous name and the name of the commodity, are related to our chemical research. Although its name is long and complex, in the field of research, the synonymous name can help communication, and the name of the commodity is related to the circulation of the market.
    In the past, the names of chemical substances all had their origins. Either according to its structure or according to its nature. This 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide, its name is derived from the structure. However, in order to make it easy for everyone to remember and use, there are also synonymous names, or simply called, or named from their nature. The name of a commodity is related to production and sales, and it also needs to attract attention and comply with regulations.
    For our researchers, being familiar with its synonymous name and commodity name can be unimpeded in the literature and market, and it is more convenient for the study of chemistry.
    Safety & Operational Standards
    Today there is a thing called 4- (5- (4 - Fluorophenyl) -3- (Trifluoromethyl) -1H - Pyrazol - 1 - Yl) Benzenesulfonamide. In our pursuit of chemical research, its safety and operating standards are of paramount importance.
    The handling of this substance is the first priority for the safety of the environment. It must be done in a well-ventilated place to prevent harmful gas from accumulating. If it is in a secret room, the gas cannot be dissipated, it will harm the person.
    Those who handle it also need protective gear. Wear corrosion-resistant gloves on your hands to prevent touching your hands; your eyes must be equipped with protective mirrors to prevent it from splashing into your eyes. Wear protective clothing and protect yourself from accidental harm.
    When taking it, use the exact amount. More is expensive, and it is easy to take risks; less is not what you want. The measuring device must be clean and accurate before it can be correct.
    When storing it, choose the adapter to hide it. Seal tightly to avoid contact with foreign objects and change. Place in a cool and dry place, away from fire sources and heat sources, to prevent accidents.
    If there is any carelessness, touch the body or enter the eye, and rinse with water as soon as possible. If something spills, don't panic, clean it up quickly according to the standard, so as not to pollute the environment and harm everyone.
    In short, the safety and operation specifications of 4- (5- (4 - Fluorophenyl) -3- (Trifluoromethyl) -1H - Pyrazol - 1 - Yl) Benzenesulfonamide are related to our safety, and it is also a smooth research.
    Application Area
    In the rise of modern chemistry, all kinds of substances have to be studied in detail. Today there is a thing called 4- (5- (4 - Fluorophenyl) -3- (Trifluoromethyl) -1H - Pyrazol - 1 - Yl) Benzenesulfonamide. This substance has many possibilities in the field of application.
    To observe the way of medicine, it may be an aid to cure diseases. The cover has a unique structure, or it can interact with the source of diseases in the body to cure various diseases. It can also be used between agriculture and plants, or it can be made as a seedling protection agent. It can control diseases and pests, ensure the safety of crops, and help farmers get a rich harvest. Furthermore, in the context of material science, it can endow materials with specificity. Make the material tough and have other wonders, used in the manufacture of equipment and utensils, increase its quality, and benefit people's livelihood. From this point of view, this chemical substance has endless potential in the application fields of medicine, agriculture and plants, and materials. It should be deeply studied to make the best use of it.
    Research & Development
    Recently, in the field of chemistry, I have focused on analyzing the compound 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide. At the beginning, the structure of its molecule was carefully examined, and the bonding formula of each atom was studied to reveal the arrangement of its space. Then, its physical properties were explored, its melting point and boiling point were measured, and its dissolution state in various solvents was observed.
    Re-study its chemical properties and observe its reaction under different conditions. After many attempts, we know where its activity check point is, what reagents are easy to react with, and what is the mechanism of the reaction. Looking at the rate at which it participates in the reaction, we can think of ways to optimize it.
    I hope to use all kinds of research to make this compound good for use in medicine, materials and other fields. Or to contribute to the creation of new drugs, or to show performance in the preparation of new materials, I hope to promote its self-research to practical use, for the development of chemistry and the well-being of mankind.
    Toxicity Research
    The industry of chemical industry is related to people's livelihood, but the study of poisons should not be careless. Today there is a product called 4- (5- (4-Fluorophenyl) -3- (Trifluoromethyl) -1H-Pyrazol-1-Yl) Benzenesulfonamide.
    We have devoted ourselves to the study of toxicity. This product has a unique chemical structure, and its fluoride and trifluoromethyl groups may affect biological activity and toxicity. After various experiments, observe its effects on organisms. Take small animals as a test to observe their behavior and physiological characteristics after ingesting this product. It may appear to be slow to move and waste diet, and the organs are also abnormal. From this perspective, the study of the toxicity of 4- (5- (4-Fluorophenyl) -3- (Trifluoromethyl) -1H-Pyrazol-1-Yl) Benzenesulfonamide should not be ignored. It should be investigated in detail to ensure the safety of people's lives and the peace of the environment.
    Future Prospects
    Fu Jin has a product named 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide. Looking at this compound, it has a delicate structure and contains fluorine and trifluoromethyl groups, giving it unique physicochemical properties.
    Looking forward to the future, it may have made extraordinary achievements in the field of medicine. With its structural characteristics, it may be able to precisely act on specific targets, develop new types of special drugs, cure various diseases, and relieve the pain of patients. In materials science, it may be able to use its unique chemical properties to produce high-performance materials, which can be used in frontier fields such as aerospace and electronics, and help make progress in science and technology.
    Our chemical researchers should diligently study and explore its potential, with the hope of opening up new horizons in the future, contributing to human well-being, and making this compound shine in the future.
    Where to Buy 4-(5-(4-Fluorophenyl)-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Benzenesulfonamide in China?
    As a trusted 4-(5-(4-Fluorophenyl)-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Benzenesulfonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-(5-(4-Fluorophenyl)-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide
    The main use of 4- (5- (4-propargyl) -3- (triethylamino) -1H-pyrazole-1-yl) phenylsulfonamide is to play a key role in many chemical synthesis and drug development fields.
    In the field of chemical synthesis, it can be used as an important intermediate in organic synthesis. With its unique chemical structure, functional groups such as propargyl, triethylamino and pyrazolyl give them special reactivity and selectivity. It can interact with other organic compounds through various chemical reactions, such as nucleophilic substitution, electrophilic addition, etc., to build more complex organic molecular structures and help synthesize organic compounds with specific structures and functions, such as new materials, natural product analogs, etc.
    In the field of drug research and development, the structural properties of this compound may make it have potential biological activity. Or it can be used as a lead compound for pharmaceutical chemists to study its interaction mechanism with biological targets in depth. Through structural modification and optimization, its pharmacological activity can be improved, and toxic and side effects can be reduced. It is expected to develop new therapeutic drugs, such as anti-tumor, anti-viral, anti-inflammatory drugs, etc., and contribute to human health. In medicinal chemistry, the in-depth study of the relationship between its structure and activity can provide an important basis for the design of more efficient and safe drugs.
    What are the chemical properties of 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide
    4- (5- (4-furyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) furanothiazolinone, which is a complex organic compound. Its chemical properties are unique, and it is related to many reaction characteristics and activity performances.
    In terms of stability, specific groups such as furyl, trifluoromethyl and pyrazolyl interact with each other in this compound, which affects its stability to a certain extent. Furan rings are aromatic, but they are also different from conventional aromatic rings due to the presence of oxygen atoms on the ring and the unique distribution of electron clouds. Trifluoromethyl is a strong electron-absorbing group, which can enhance molecular polarity, affect intermolecular forces, and then have an effect on overall stability. The pyrazole ring contains two adjacent nitrogen atoms, and its electronic structure endows pyrazolyl with unique chemical activity and stability. These groups work synergistically to determine the stability of the compound.
    On reactivity, the strong electron-absorbing properties of trifluoromethyl make the electron cloud density of the carbon atoms connected to it decrease, making it vulnerable to attack by nucleophiles and triggering nucleophilic substitution reactions. Pyrazole ring nitrogen atoms contain lone pair electrons, which can participate in reactions as electron donors, such as forming complexes with metal ions or acting as nucleophiles in organic synthesis. In addition, the furan ring, as an electron-rich aromatic ring, is prone to electrophilic substitution reactions, especially under suitable conditions, the introduction of substituents at specific positions on the ring.
    In terms of solubility, the compound contains multiple polar groups, which makes it more soluble in polar organic solvents such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), but it has poor solubility in non-polar solvents such as n-hexane and toluene. This solubility characteristic needs to be taken into account when separating, purifying compounds and selecting reaction solvents.
    In terms of acidity and alkalinity, the nitrogen atom of the pyrazole ring can accept protons and presents a certain alkalinity, but its alkalinity changes due to the influence of electronic effects of other groups in the molecule. The groups such as furan ring and trifluoromethyl also have indirect effects on acidity and alkalinity, and the overall acidity and alkalinity determine the form and reactivity of the compound in different pH environments.
    What is the synthesis method of 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide
    To prepare 4- (5- (4-thiophenyl) -3- (trithiophenyl) -1H-pyrrole-1-yl) thiopheno [2,3-b] pyridine, the following ancient methods can be used.
    First take appropriate starting materials, such as compounds containing thiophenyl and pyridine structures, both of which need to have reactive activity check points to facilitate subsequent bonding reactions. It is better to modify thiophene and pyridine derivatives with halogen atoms or active functional groups, such as chlorine, bromine, etc., and active functional groups such as aldehyde, carboxyl, and amino groups.
    First, the pyridine derivative and the thiophene derivative are reacted under specific reaction conditions. Metal catalytic coupling reaction is often used as the main method, such as palladium, nickel and other metal catalysts. In an inert gas-protected environment, the reactants, catalysts, ligands and bases are placed in a suitable organic solvent and heated and stirred. The organic solvent can be selected from dichloromethane, N, N-dimethylformamide, etc., depending on the solubility of the reactants. The base can be selected from an inorganic base such as potassium carbonate and sodium carbonate, or an organic base such as triethylamine. This reaction aims to form a connection structure between pyridine and thiophene and build a basic skeleton of the target molecule.
    After the initial skeleton is formed, the specific sites in it are functionally converted or modified. If other thiophenyl groups need to be introduced, the above metal catalytic coupling steps can be repeated, or the nucleophilic substitution reaction can be selected, depending on the characteristics of the existing functional groups in the molecule. For example, if a halogen atom is in place, it can react with a nucleophilic reagent containing thiophenyl groups.
    During the reaction process, thin-layer chromatography, nuclear magnetic resonance and other means need to be monitored. TLC can detect the changes of each component in the reaction mixture in real time to determine whether the reaction is carried out and whether it is complete. After the reaction is completed, NMR can accurately analyze the structure of the product and confirm that it is the target product.
    After the reaction is completed, the purified product is obtained by conventional separation and purification methods. First, the product is extracted and separated from the reaction mixture with organic solvents of different polarities. Then column chromatography is performed, appropriate silica gel or other fillers are selected, and rinsed with different proportions of eluent to obtain high purity 4- (5- (4-thiophenyl) -3- (trithiophenyl) -1H-pyrrole-1-yl) thiopheno [2,3-b] pyridine.
    What is the market outlook for 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide?
    4- (5- (4-furyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) furanothiophene formaldehyde, which is a class of organic compounds. Looking at its market prospects, it can be analyzed from the following aspects.
    In the field of medicine, such compounds containing specific groups may have unique biological activities. Furyl, trifluoromethyl and pyrazolyl, etc., often endow molecules with unique physical, chemical and biological properties. For example, some compounds containing furan groups perform well in antibacterial and anti-inflammatory aspects; the introduction of trifluoromethyl can enhance the lipophilicity of compounds, improve their absorption and distribution in vivo, and then affect their pharmacological activity. Therefore, if the compound is further researched and developed, it may become a lead compound for new drugs, and find a place in the field of innovative drug research and development, and the market potential should not be underestimated.
    In the field of materials science, such compounds may have unique optical and electrical properties due to their special structures. For example, some compounds containing heterocyclic structures can be used to prepare organic Light Emitting Diode (OLED) materials because they can effectively transport charges and emit photons. If this compound is optimized, it may have applications in OLED display technology, organic photovoltaic cells and other fields. With the vigorous development of display technology and new energy industries, its market demand may gradually increase.
    However, its market development also faces challenges. First, the synthesis of such complex compounds may require cumbersome steps and expensive raw materials, and the production cost is high, which is not conducive to large-scale production and marketing activities. Second, new compounds enter the market and need to go through strict testing and approval processes, especially in the pharmaceutical field. Pre-clinical and clinical trials are time-consuming and costly, and there is a risk of R & D failure.
    Overall, 4- (5- (4-furyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) furanothiophene formaldehyde has potential application value and market prospects, but to achieve its commercial success, it is necessary to overcome many problems such as synthesis cost and research and development risk.
    What are the side effects of 4- (5- (4-fluorophenyl) -3- (trifluoromethyl) -1H-pyrazole-1-yl) benzenesulfonamide
    4- (5- (4-tritium) -3- (trideuteromethyl) -1H-pyrrole-1-yl) pyridine-2-formaldehyde, this compound has a variety of potential side effects, and is now described in ancient form.
    If this substance is used in the human body, it should be the root of its impact, or disturb the movement of people. If it is disturbed by it, it will not be smooth. Stagnation will cause blood stasis, which can cause pain in various parts of the body. The pain may be like a needle, and it will not move. For example, "Lingshu · Meridians" says: "The meridians are connected, but you can walk." Under the disturbance of this thing, the meridians may be blocked, and it is difficult to smooth.
    Furthermore, it may damage the function of people's internal organs. The internal organs, each performing its own duties, coordinate their operation, and everyone is healthy. Then this object enters the body, or hurts the spleen and stomach. Those with the spleen and stomach are the foundation of the day after tomorrow, and the source of the birth and transformation. If the spleen and stomach are damaged, the transportation and transformation will be abnormal, and people may experience narcolepsy, abdominal distension, loose stools, etc. As stated in "Suwen · Yin and Yang should be like a great theory": "The spleen governs the transportation and transformation, and the stomach governs the acceptance." If the spleen and stomach are discordant, it
    Or it has an effect on people's spiritual mind. The main god, the brain is the palace of the primordial spirit. This thing may disturb the mind, make people upset, unable to sleep at night, and even maniac. "Lingshu · Benshen" says: "The heart hides the gods, and the pulse gives up the gods." This thing or the heart is chaotic, causing the mind to be unable to give up, and the mind is chaotic.
    And this thing is metabolized in the body, or produces toxic intermediates. These products can further damage the body's tissue cells, involving multiple systems, such as the respiratory system, which can cause asthma and cough; the urinary system, which can cause frequent urination, urgency, etc.
    All these side effects must be observed carefully, and their advantages and disadvantages must be carefully examined to ensure people's health.