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What is the chemical structure of 4,4 '- [Benzene-1,4-Diylbis (Oxy) ] Bis [3- (Trifluoromethyl) Aniline]?
This compound is named 4,4 '- [benzene-1,4-diyl bis (oxy) ] bis [3- (trifluoromethyl) aniline], and its chemical structure is analyzed as follows:
The core of this compound is a benzene ring, and there are two oxygen groups (-O-) connected at the 1,4 positions of the benzene ring. The other side of the oxygen group is connected to the 3- (trifluoromethyl) aniline structure. In the 3- (trifluoromethyl) aniline structure, the amino group (-NH2O) is connected to the benzene ring, and there is a trifluoromethyl group (-CF 🥰) in the amino interposition (ie, the 3 position).
In summary, the structure of this compound is centered on the benzene ring, and two 3- (trifluoromethyl) aniline structures are connected by two oxygen groups to form a unique chemical structure.
What are the main physical properties of 4,4 '- [Benzene-1,4-Diylbis (Oxy) ] Bis [3- (Trifluoromethyl) Aniline]?
4,4 '- [benzene-1,4-diyl bis (oxy) ] bis [3- (trifluoromethyl) aniline] is an organic compound. Its main physical properties are as follows:
In terms of appearance properties, it is mostly white to light yellow crystalline powder at room temperature and pressure. This form is easy to store and transport, and in many chemical reactions, the powdered substance can provide a large specific surface area, making the reaction easier to occur.
Melting point is about 118-122 ° C. As an important physical constant of a substance, the melting point can be used to identify the purity of the compound. If the melting point of the sample is consistent with the standard value and the melting range is narrow, it indicates high purity; if the melting range is wide and deviates from the standard melting point, it may contain impurities.
In terms of solubility, it is insoluble in water, but soluble in common organic solvents, such as dichloromethane, N, N-dimethylformamide, etc. This solubility characteristic makes it possible to realize dissolution, extraction and other operations with the help of suitable organic solvents in the process of organic synthesis, separation and purification.
In terms of density, its density is about 1.43 g/cm ³. Density is of great significance for the reaction or separation process in solution, and can be used to calculate the mass of the substance at a specific volume. It plays a key guiding role in the ratio of reactants and product separation. In terms of stability, the compound is relatively stable under conventional conditions, but it should be avoided from contact with strong oxidants, strong acids, strong bases and other substances to prevent chemical reactions from causing its structure to change. When storing, store in a cool, dry and well-ventilated place, away from fire and heat sources.
In what fields is 4,4 '- [Benzene-1,4-Diylbis (Oxy) ] Bis [3- (Trifluoromethyl) Aniline] used?
4,4 '- [benzene-1,4-diyl bis (oxy) ] bis [3- (trifluoromethyl) aniline], this compound has applications in many fields. In the field of materials science, due to its special structure, it can be used to prepare high-performance polymer materials. Its fluorine-containing structure endows the material with excellent chemical stability and low surface energy, resulting in excellent waterproof, oil-proof and anti-fouling properties. For example, it can be used in high-end architectural glass coatings to effectively resist external erosion and maintain cleanliness for a long time. In the field of electronics, it can be used as an organic semiconductor material component. Its molecular structure is conducive to charge transport, which has a positive effect on improving the performance of organic electronic devices such as organic Light Emitting Diodes (OLEDs) and organic field effect transistors (OFETs), or can improve the luminous efficiency and service life of OLEDs, and help the development of display technology. In the field of medicinal chemistry, because it contains specific functional groups, it can be used as lead compounds for drug research and development. Through chemical modification, it is expected to develop drugs with unique biological activities, such as new anti-cancer or anti-infective drugs targeting specific disease targets, contributing to the cause of human health.
What are the synthesis methods of 4,4 '- [Benzene-1,4-Diylbis (Oxy) ] Bis [3- (Trifluoromethyl) Aniline]?
The synthesis method of 4,4 '- [benzene-1,4-diyl bis (oxy) ] bis [3- (trifluoromethyl) aniline] has the following methods:
First, the compound containing benzene-1,4-diphenol structure and the compound containing 3- (trifluoromethyl) aniline structure and halogenated alkoxy group can be obtained by nucleophilic substitution in an alkaline environment and in the presence of an appropriate catalyst. In this reaction, the basic substance can help deprotonate the phenolic hydroxyl group, enhance its nucleophilicity, and facilitate the substitution with the halogenated alkoxy compound to form the ether bond structure of the target product.
Second, the strategy can be gradually constructed. First, an intermediate containing benzene-1,4-dioxy at one end and a protective group is synthesized, and then the protective group is removed and condensed with another intermediate containing 3- (trifluoromethyl) aniline structure. This process requires careful selection of protective groups, so that they can not only effectively protect specific functional groups in the reaction, but also be gently removed at an appropriate stage without affecting other structures.
Third, there is also a cross-coupling reaction pathway catalyzed by transition metals. If a suitable palladium catalyst is selected, the benzene-1,4-diphenol derivative and the halogenated aromatic hydrocarbon containing 3- (trifluoromethyl) aniline structure are coupled in the presence of ligands and bases to form the desired carbon-oxygen bond to achieve the synthesis of the target product. This method requires more stringent reaction conditions, and the selection of catalysts and ligands needs to be carefully considered to ensure the high efficiency and selectivity of the reaction.
Each synthesis method has its own advantages and disadvantages. The appropriate method should be carefully selected according to the actual availability of raw materials, the operability of reaction conditions, and the purity requirements of the target product.
What is the market outlook for 4,4 '- [Benzene-1,4-Diylbis (Oxy) ] Bis [3- (Trifluoromethyl) Aniline]?
4,4 '- [benzene-1,4-diyl bis (oxy) ] bis [3- (trifluoromethyl) aniline], its market prospects are related to various factors. In today's view, this compound is often a key intermediate in organic synthesis in the field of scientific research. Due to its special structure, the combination of fluorine-containing groups and phenoxy groups endows it with unique physical and chemical properties, and has potential in materials science, pharmaceutical chemistry and other fields.
In materials science, it can be used to create high-performance polymer materials. Coating fluorine-containing structures can improve the thermal stability, chemical stability and weather resistance of materials, and is expected to be used in high-end fields such as aerospace, electronics and electrical appliances. For example, the components of aviation equipment require materials that can withstand extreme environments. The materials involved in the synthesis of this compound may meet their requirements, so the market demand for it may grow with the development of high-end manufacturing.
In pharmaceutical chemistry, fluoroaniline-containing compounds often have good biological activities and pharmacokinetic properties. Innovative drugs developed on the basis of them may show unique effects on specific diseases. With the increasing global demand for innovative drugs, the market prospect of this compound as a precursor for drug synthesis is also quite promising.
However, its market expansion also faces challenges. The complexity of the synthesis process or the high production cost limit its large-scale application. And the market competition is fierce, and the emergence of new synthetic methods and alternative compounds may also pose a threat to its market share. But overall, if the synthesis problem can be overcome and the cost can be reduced, with its unique properties, driven by the emerging high-tech industry, 4,4 '- [benzene-1,4-diyl bis (oxy) ] bis [3- (trifluoromethyl) aniline] still has broad market prospects, and is expected to emerge in the field of materials and drugs and gain market favor.